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ONTOLOGY REPORT - ANNOTATIONS

Term:RNA endonuclease activity
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Accession:GO:0004521 term browser browse the term
Definition:Catalysis of the hydrolysis of ester linkages within ribonucleic acid by creating internal breaks.
Synonyms:exact_synonym: endoribonuclease activity
 related_synonym: endonuclease G activity
 xref: Reactome:R-HSA-9708327 "ANG cleaves tRNA to yield tRNA halves";   Reactome:R-HSA-9708812 "ELAC2 cleaves pre-tRNA to yield 3' trailer (type II tRF or tRF-1)";   reactome:R-HSA-425923 "IRE1alpha hydrolyzes Xbp1 mRNA and Xbp1 mRNA is spliced";   reactome:R-HSA-426520 "Endonucleolytic RISC hydrolyzes target RNAs";   reactome:R-HSA-5601887 "PLD6 dimer cleaves primary piRNA transcript to pre-piRNA";   reactome:R-HSA-5601910 "Complexed PIWIL2:2'-O-methyl-piRNA cleaves transposon RNA";   reactome:R-HSA-6791223 "18SE pre-rRNA in pre-40S particles is nucleolytically processed during translocation from the nucleus to the cytosol";   reactome:R-HSA-6814555 "Integrator complex processes the 3' end of snRNA";   reactome:R-HSA-9009936 "RNASEL cleaves cellular ssRNA";   reactome:R-HSA-9009941 "RNASEL cleaves viral ssRNA";   reactome:R-HSA-9023909 "C3PO hydrolyzes cleaved passenger strand";   reactome:R-HSA-9023912 "AGO2 cleaves passenger strand of duplex siRNA";   reactome:R-HSA-927836 "SMG6 hydrolyzes mRNA with premature termination codon"


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RNA endonuclease activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ago1 argonaute RISC catalytic subunit 1 NOT|enables ISO (PMID:23809764) UniProt PMID:23809764 NCBI chr 4:126,328,805...126,362,500
Ensembl chr 4:126,328,805...126,362,376 		JBrowse link
G Ago2 argonaute RISC catalytic subunit 2 enables ISO
IBA
IDA		 (PMID:20424607) MGI
GO_Central		 PMID:20424607 GO_REF:0000033 GO_REF:0000119 MGI:4834177 NCBI chr15:72,967,693...73,056,777
Ensembl chr15:72,967,693...73,056,784 		JBrowse link
G Ago3 argonaute RISC catalytic subunit 3 enables ISO
ISS
IBA		 MGI
UniProt
GO_Central		 GO_REF:0000024 GO_REF:0000033 GO_REF:0000119 MGI:4834177 NCBI chr 4:126,220,797...126,323,360
Ensembl chr 4:126,225,497...126,323,349 		JBrowse link
G Ago4 argonaute RISC catalytic subunit 4 enables IBA GO_Central GO_REF:0000033 NCBI chr 4:126,383,280...126,427,379
Ensembl chr 4:126,383,334...126,427,265 		JBrowse link
G Ankzf1 ankyrin repeat and zinc finger domain containing 1 enables ISO
ISS		 MGI
UniProt
GO_Central		 GO_REF:0000024 GO_REF:0000119 MGI:4834177 NCBI chr 1:75,168,794...75,176,031
Ensembl chr 1:75,168,795...75,176,031 		JBrowse link
G Apex1 apurinic/apyrimidinic endonuclease 1 enables ISO MGI
RGD		 PMID:19401441 GO_REF:0000096 MGI:4417868 RGD:2315668 NCBI chr14:51,162,406...51,164,645
Ensembl chr14:51,162,425...51,164,596 		JBrowse link
G Cpsf3 cleavage and polyadenylation specificity factor 3 enables IDA
IBA
ISO		 (MGI:4418605|PMID:18955505) UniProt
GO_Central
MGI		 PMID:18955505 GO_REF:0000033 GO_REF:0000119 MGI:4418605 MGI:4834177 NCBI chr12:21,336,298...21,365,057
Ensembl chr12:21,335,392...21,365,057 		JBrowse link
G Dicer1 dicer 1, ribonuclease type III enables ISO MGI
GO_Central		 GO_REF:0000119 MGI:4834177 NCBI chr12:104,654,001...104,718,331
Ensembl chr12:104,654,001...104,718,211 		JBrowse link
G Drosha drosha, ribonuclease type III enables IDA (PMID:20424607) MGI PMID:20424607 NCBI chr15:12,824,893...12,935,377
Ensembl chr15:12,824,901...12,935,377 		JBrowse link
G Endog endonuclease G enables IBA GO_Central GO_REF:0000033 NCBI chr 2:30,061,525...30,064,057
Ensembl chr 2:30,061,505...30,064,081 		JBrowse link
G Endou endonuclease, polyU-specific enables ISO
ISS
IBA		 MGI
GO_Central
UniProt		 GO_REF:0000024 GO_REF:0000033 GO_REF:0000119 MGI:4834177 NCBI chr15:97,608,896...97,629,286
Ensembl chr15:97,608,896...97,629,220 		JBrowse link
G Ern1 endoplasmic reticulum to nucleus signalling 1 enables ISO
IBA
IDA		 (PMID:15601821), (PMID:25164867) MGI
GO_Central
WB		 PMID:15601821 PMID:25164867 GO_REF:0000033 GO_REF:0000119 MGI:4834177 NCBI chr11:106,285,474...106,378,701
Ensembl chr11:106,285,476...106,378,678 		JBrowse link
G Ern2 endoplasmic reticulum to nucleus signalling 2 enables IBA
IEA		 GO_Central
InterPro		 GO_REF:0000002 GO_REF:0000033 NCBI chr 7:121,769,116...121,785,454
Ensembl chr 7:121,769,116...121,785,430 		JBrowse link
G Exog exo/endonuclease G enables IBA GO_Central GO_REF:0000033 NCBI chr 9:119,274,026...119,294,584
Ensembl chr 9:119,274,009...119,294,583 		JBrowse link
G Ints11 integrator complex subunit 11 enables ISO
IBA		 MGI
GO_Central		 GO_REF:0000033 GO_REF:0000119 MGI:4834177 NCBI chr 4:155,954,006...155,973,561
Ensembl chr 4:155,954,003...155,973,560 		JBrowse link
G Khnyn KH and NYN domain containing enables IBA GO_Central GO_REF:0000033 NCBI chr14:56,122,269...56,136,237
Ensembl chr14:56,122,404...56,136,232
Ensembl chr14:56,122,404...56,136,232 		JBrowse link
G Lactb2 lactamase, beta 2 enables ISO
IBA		 MGI
GO_Central		 GO_REF:0000033 GO_REF:0000119 MGI:4834177 NCBI chr 1:13,695,069...13,730,749
Ensembl chr 1:13,693,554...13,730,770 		JBrowse link
G Mblac1 metallo-beta-lactamase domain containing 1 enables ISO
ISS		 MGI
UniProt
GO_Central		 GO_REF:0000024 GO_REF:0000119 MGI:4834177 NCBI chr 5:138,192,576...138,193,883
Ensembl chr 5:138,192,576...138,193,883 		JBrowse link
G Nob1 NIN1/RPN12 binding protein 1 homolog enables ISO
IEA
IBA		 MGI
InterPro
GO_Central		 GO_REF:0000002 GO_REF:0000033 GO_REF:0000119 MGI:4834177 NCBI chr 8:108,139,121...108,151,670
Ensembl chr 8:108,139,118...108,151,683 		JBrowse link
G Nynrin NYN domain and retroviral integrase containing enables IBA GO_Central GO_REF:0000033 NCBI chr14:56,091,572...56,112,193
Ensembl chr14:56,091,467...56,112,193 		JBrowse link
G Piwil1 piwi-like RNA-mediated gene silencing 1 enables IMP
IBA		 (MGI:5316869|PMID:22121019) UniProt
GO_Central		 PMID:22121019 GO_REF:0000033 MGI:5316869 NCBI chr 5:128,813,135...128,832,538
Ensembl chr 5:128,779,588...128,832,538 		JBrowse link
G Piwil2 piwi-like RNA-mediated gene silencing 2 enables IMP
IDA
IBA		 (MGI:5319753|PMID:22020280), (MGI:5501381|PMID:23706823)
(PMID:22020280), (PMID:23706823)
(PMID:28633017)
(MGI:5908740|PMID:28633017)		 UniProt
GO_Central		 PMID:22020280 PMID:23706823 PMID:28633017 GO_REF:0000033 MGI:5319753 MGI:5501381 MGI:5908740 NCBI chr14:70,609,926...70,674,338
Ensembl chr14:70,609,926...70,666,832 		JBrowse link
G Piwil4 piwi-like RNA-mediated gene silencing 4 NOT|enables IMP (MGI:5319753|PMID:22020280) UniProt PMID:22020280 MGI:5319753 NCBI chr 9:14,613,072...14,651,968
Ensembl chr 9:14,607,526...14,652,036 		JBrowse link
G Rcl1 RNA terminal phosphate cyclase-like 1 enables IBA GO_Central GO_REF:0000033 NCBI chr19:29,078,761...29,121,251
Ensembl chr19:29,078,775...29,121,329 		JBrowse link
G Rnasek ribonuclease, RNase K enables ISO
IBA		 MGI
GO_Central		 GO_REF:0000033 GO_REF:0000119 MGI:4834177 NCBI chr11:70,128,949...70,130,678
Ensembl chr11:70,126,032...70,130,656
Ensembl chr11:70,126,032...70,130,656 		JBrowse link
G Rnaset2a ribonuclease T2A enables IBA GO_Central GO_REF:0000033 NCBI chr17:8,347,412...8,367,078
Ensembl chr17:8,334,277...8,366,929 		JBrowse link
G Rnaset2b ribonuclease T2B enables IBA GO_Central GO_REF:0000033 NCBI chr17:7,246,259...7,265,592
Ensembl chr17:7,238,033...7,278,698 		JBrowse link
G Slfn14 schlafen 14 enables IDA
IBA
ISO		 (MGI:5705207|PMID:25996083)
(PMID:25996083)		 UniProt
GO_Central
MGI		 PMID:25996083 GO_REF:0000033 GO_REF:0000119 MGI:4834177 MGI:5705207 NCBI chr11:83,165,936...83,177,552
Ensembl chr11:83,165,936...83,177,552 		JBrowse link
G Slfn8 schlafen 8 enables ISO
IDA		 (PMID:29563550)
(MGI:6149438|PMID:29563550)		 MGI
UniProt
GO_Central		 PMID:29563550 GO_REF:0000096 GO_REF:0000119 MGI:4417868 MGI:4834177 MGI:6149438 NCBI chr11:82,892,984...82,911,636
Ensembl chr11:82,892,984...82,911,636 		JBrowse link
G Slfn9 schlafen 9 enables ISO MGI GO_REF:0000096 GO_REF:0000119 MGI:4417868 MGI:4834177 NCBI chr11:82,865,142...82,883,041
Ensembl chr11:82,869,216...82,882,656 		JBrowse link
G Smg6 SMG6 nonsense mediated mRNA decay factor enables ISO
ISS		 MGI
UniProt
GO_Central		 GO_REF:0000024 GO_REF:0000119 MGI:4834177 NCBI chr11:74,816,665...75,055,274
Ensembl chr11:74,816,649...75,055,274 		JBrowse link
G Snd1 staphylococcal nuclease and tudor domain containing 1 enables ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 6:28,480,332...28,935,161
Ensembl chr 6:28,475,138...28,935,161 		JBrowse link
G Tsnax translin-associated factor X enables IBA GO_Central GO_REF:0000033 NCBI chr 8:125,739,780...125,760,947
Ensembl chr 8:125,739,736...125,760,931 		JBrowse link
G Ybey ybeY metallopeptidase enables ISO MGI
GO_Central		 GO_REF:0000119 MGI:4834177 NCBI chr10:76,295,401...76,304,948
Ensembl chr10:76,295,401...76,304,948 		JBrowse link
G Zc3h12a zinc finger CCCH type containing 12A enables IDA
IBA		 (MGI:5706859|PMID:26000482), (MGI:5706911|PMID:22055188), (MGI:5751631|PMID:26255671)
(PMID:22055188), (PMID:26000482), (PMID:26255671)		 UniProt
GO_Central		 PMID:22055188 PMID:26000482 PMID:26255671 GO_REF:0000033 MGI:5706859 MGI:5706911 MGI:5751631 NCBI chr 4:125,012,207...125,021,674
Ensembl chr 4:125,012,216...125,021,633 		JBrowse link
G Zc3h12b zinc finger CCCH-type containing 12B enables IBA GO_Central GO_REF:0000033 NCBI chr  X:94,755,206...94,976,262
Ensembl chr  X:94,755,284...94,976,243 		JBrowse link
G Zc3h12c zinc finger CCCH type containing 12C enables IBA GO_Central GO_REF:0000033 NCBI chr 9:52,020,869...52,080,028
Ensembl chr 9:52,022,644...52,079,872 		JBrowse link
G Zc3h12d zinc finger CCCH type containing 12D enables IBA GO_Central GO_REF:0000033 NCBI chr10:7,708,087...7,746,161
Ensembl chr10:7,708,234...7,746,160 		JBrowse link
3'-tRNA processing endoribonuclease activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Elac1 elaC ribonuclease Z 1 enables IBA GO_Central GO_REF:0000033 NCBI chr18:73,868,109...73,887,589
Ensembl chr18:73,868,109...73,887,550 		JBrowse link
G Elac2 elaC ribonuclease Z 2 enables IBA
IEA		 GO_Central
UniProt		 GO_REF:0000003 GO_REF:0000033 NCBI chr11:64,869,856...64,892,906
Ensembl chr11:64,869,864...64,892,895 		JBrowse link
endoribonuclease activity, cleaving miRNA-paired mRNA term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ago2 argonaute RISC catalytic subunit 2 enables ISO
IEA		 MGI
Ensembl		 GO_REF:0000107 GO_REF:0000119 MGI:4834177 NCBI chr15:72,967,693...73,056,777
Ensembl chr15:72,967,693...73,056,784 		JBrowse link
G Ago3 argonaute RISC catalytic subunit 3 enables ISO
ISS		 MGI
GO_Central
UniProt		 GO_REF:0000024 GO_REF:0000119 MGI:4834177 NCBI chr 4:126,220,797...126,323,360
Ensembl chr 4:126,225,497...126,323,349 		JBrowse link
endoribonuclease activity, cleaving siRNA-paired mRNA term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ago2 argonaute RISC catalytic subunit 2 enables TAS
ISS
ISO		 Reactome
UniProt
MGI		 GO_REF:0000024 GO_REF:0000119 MGI:4834177 Reactome:R-MMU-9820863 NCBI chr15:72,967,693...73,056,777
Ensembl chr15:72,967,693...73,056,784 		JBrowse link
phosphodiesterase decapping endonuclease activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nudt12 nudix hydrolase 12 enables ISO MGI
GO_Central		 GO_REF:0000119 MGI:4834177 NCBI chr17:59,307,104...59,320,317
Ensembl chr17:59,306,613...59,320,367 		JBrowse link
G Nudt16 nudix hydrolase 16 enables ISO
IBA		 MGI
GO_Central		 GO_REF:0000033 GO_REF:0000119 MGI:4834177 NCBI chr 9:105,006,531...105,010,332
Ensembl chr 9:105,006,102...105,009,023 		JBrowse link
G Nudt16l1 nudix hydrolase 16 like 1 NOT|enables IBA GO_Central GO_REF:0000033 NCBI chr16:4,756,975...4,758,892
Ensembl chr16:4,756,625...4,758,896 		JBrowse link
G Nudt16l2 nudix hydrolase 16 like 2 enables IBA GO_Central GO_REF:0000033 NCBI chr 9:105,020,543...105,022,281
Ensembl chr 9:105,020,541...105,022,291 		JBrowse link
ribonuclease A activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ear4 eosinophil-associated, ribonuclease A family, member 4 enables IEA UniProt GO_REF:0000003 MGI:2152096
G Rnase1 ribonuclease, RNase A family, 1 (pancreatic) enables IEA UniProt GO_REF:0000003 MGI:2152096 NCBI chr14:51,382,459...51,384,224
Ensembl chr14:51,382,455...51,384,242 		JBrowse link
G Rnase2b ribonuclease, RNase A family, 2B (liver, eosinophil-derived neurotoxin) enables IEA UniProt GO_REF:0000003 MGI:2152096 NCBI chr14:51,399,717...51,400,475
Ensembl chr14:51,399,717...51,400,475 		JBrowse link
ribonuclease III activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dicer1 dicer 1, ribonuclease type III enables TAS
IBA
ISO		 Reactome
GO_Central
MGI		 GO_REF:0000033 GO_REF:0000119 MGI:4834177 Reactome:R-MMU-9709033 Reactome:R-MMU-9820882 NCBI chr12:104,654,001...104,718,331
Ensembl chr12:104,654,001...104,718,211 		JBrowse link
G Drosha drosha, ribonuclease type III enables ISO
IEA
IBA		 MGI
UniProt
GO_Central		 GO_REF:0000003 GO_REF:0000033 GO_REF:0000119 MGI:4834177 NCBI chr15:12,824,893...12,935,377
Ensembl chr15:12,824,901...12,935,377 		JBrowse link
G Mrpl44 mitochondrial ribosomal protein L44 enables IEA UniProt
InterPro		 GO_REF:0000002 MGI:2152098 NCBI chr 1:79,753,735...79,759,162
Ensembl chr 1:79,753,735...79,759,162 		JBrowse link
ribonuclease MRP activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pop5 processing of precursor 5, ribonuclease P/MRP family (S. cerevisiae) enables ISA (PMID:11413139) MGI PMID:11413139 NCBI chr 5:115,373,505...115,379,031
Ensembl chr 5:115,373,895...115,383,410 		JBrowse link
G Rpp40 ribonuclease P 40 subunit contributes_to IBA GO_Central GO_REF:0000033 NCBI chr13:36,080,685...36,095,548
Ensembl chr13:36,077,455...36,090,342 		JBrowse link
ribonuclease P activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pop1 processing of precursor 1, ribonuclease P/MRP family, (S. cerevisiae) contributes_to ISO MGI
GO_Central		 GO_REF:0000119 MGI:4834177 NCBI chr15:34,495,457...34,530,799
Ensembl chr15:34,495,450...34,530,794 		JBrowse link
G Pop4 processing of precursor 4, ribonuclease P/MRP family, (S. cerevisiae) contributes_to ISO
ISS		 MGI
UniProt
GO_Central		 GO_REF:0000024 GO_REF:0000119 MGI:4834177 NCBI chr 7:37,962,239...37,970,803
Ensembl chr 7:37,961,420...37,970,847 		JBrowse link
G Pop5 processing of precursor 5, ribonuclease P/MRP family (S. cerevisiae) contributes_to
enables		 ISO
IDA		 (PMID:11413139) MGI
GO_Central		 PMID:11413139 GO_REF:0000119 MGI:4834177 NCBI chr 5:115,373,505...115,379,031
Ensembl chr 5:115,373,895...115,383,410 		JBrowse link
G Pop7 processing of precursor 7, ribonuclease P family, (S. cerevisiae) contributes_to ISO MGI
GO_Central		 GO_REF:0000119 MGI:4834177 NCBI chr 5:137,499,701...137,500,682
Ensembl chr 5:137,499,700...137,500,780 		JBrowse link
G Prorp protein only RNase P catalytic subunit enables ISO
ISS
IBA		 MGI
UniProt
GO_Central		 GO_REF:0000024 GO_REF:0000033 GO_REF:0000119 MGI:4834177 NCBI chr12:55,349,422...55,429,276
Ensembl chr12:55,346,362...55,429,318 		JBrowse link
G Rpp14 ribonuclease P 14 subunit contributes_to ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr14:14,377,927...14,389,460
Ensembl chr14:14,377,939...14,389,406 		JBrowse link
G Rpp21 ribonuclease P 21 subunit contributes_to
enables		 ISO
IEA		 MGI
UniProt		 GO_REF:0000003 GO_REF:0000119 MGI:4834177 NCBI chr17:36,566,565...36,568,738
Ensembl chr17:36,566,537...36,568,961 		JBrowse link
G Rpp25 ribonuclease P/MRP 25 subunit contributes_to ISO
ISS		 MGI
GO_Central
UniProt		 GO_REF:0000024 GO_REF:0000119 MGI:4834177 NCBI chr 9:57,411,385...57,412,730
Ensembl chr 9:57,411,309...57,412,731 		JBrowse link
G Rpp30 ribonuclease P/MRP 30 subunit contributes_to
enables		 ISO
IEA		 MGI
UniProt
GO_Central		 GO_REF:0000003 GO_REF:0000119 MGI:4834177 NCBI chr19:36,061,118...36,082,173
Ensembl chr19:36,061,116...36,082,177 		JBrowse link
G Rpp38 ribonuclease P/MRP 38 subunit contributes_to ISO
IBA		 MGI
GO_Central		 GO_REF:0000033 GO_REF:0000119 MGI:4834177 NCBI chr 2:3,328,305...3,334,023
Ensembl chr 2:3,329,986...3,333,680 		JBrowse link
G Rpp40 ribonuclease P 40 subunit contributes_to
enables		 ISO
IBA		 (PMID:9630247) MGI
GO_Central		 PMID:9630247 GO_REF:0000033 GO_REF:0000119 MGI:4834177 NCBI chr13:36,080,685...36,095,548
Ensembl chr13:36,077,455...36,090,342 		JBrowse link
ribonuclease T2 activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rnaset2a ribonuclease T2A enables IEA UniProt GO_REF:0000003 NCBI chr17:8,347,412...8,367,078
Ensembl chr17:8,334,277...8,366,929 		JBrowse link
G Rnaset2b ribonuclease T2B enables IEA UniProt GO_REF:0000003 NCBI chr17:7,246,259...7,265,592
Ensembl chr17:7,238,033...7,278,698 		JBrowse link
RNA endonuclease activity, producing 3'-phosphomonoesters term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rida reactive intermediate imine deaminase A homolog enables ISO
ISS		 MGI
UniProt
RGD		 PMID:10400702 GO_REF:0000024 GO_REF:0000096 MGI:4417868 RGD:9685547 NCBI chr15:34,484,168...34,495,392
Ensembl chr15:34,484,167...34,495,401 		JBrowse link
RNA endonuclease activity, producing 5'-phosphomonoesters term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dicer1 dicer 1, ribonuclease type III enables IEA UniProt GO_REF:0000002 MGI:2152098 NCBI chr12:104,654,001...104,718,331
Ensembl chr12:104,654,001...104,718,211 		JBrowse link
G Elac1 elaC ribonuclease Z 1 enables IEA UniProt GO_REF:0000002 MGI:2152098 NCBI chr18:73,868,109...73,887,589
Ensembl chr18:73,868,109...73,887,550 		JBrowse link
G Endov endonuclease V enables ISO
ISS
IBA		 MGI
UniProt
GO_Central		 GO_REF:0000024 GO_REF:0000033 GO_REF:0000119 MGI:4834177 NCBI chr11:119,382,173...119,402,291
Ensembl chr11:119,382,173...119,402,263 		JBrowse link
G Pld6 phospholipase D family member 6 enables IBA GO_Central GO_REF:0000033 NCBI chr11:59,674,719...59,678,483
Ensembl chr11:59,674,723...59,678,471 		JBrowse link
RNA lariat debranching enzyme activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dbr1 debranching RNA lariats 1 enables ISO
ISS
IBA
IDA		 (PMID:10982890) MGI
GO_Central
UniProt		 PMID:10982890 GO_REF:0000024 GO_REF:0000033 GO_REF:0000119 MGI:4834177 NCBI chr 9:99,457,839...99,467,060
Ensembl chr 9:99,457,852...99,466,554 		JBrowse link
RNA-DNA hybrid ribonuclease activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fen1 flap structure specific endonuclease 1 enables ISO
IBA		 MGI
GO_Central		 GO_REF:0000033 GO_REF:0000119 MGI:4834177 NCBI chr19:10,176,496...10,181,757
Ensembl chr19:10,176,496...10,181,533 		JBrowse link
G Nynrin NYN domain and retroviral integrase containing enables IEA UniProt GO_REF:0000002 MGI:2152098 NCBI chr14:56,091,572...56,112,193
Ensembl chr14:56,091,467...56,112,193 		JBrowse link
G Rnaseh1 ribonuclease H1 enables ISO
IBA
IDA
ISS		 (PMID:15831789)
(PMID:9799596)		 MGI
GO_Central		 PMID:9799596 PMID:15831789 GO_REF:0000033 GO_REF:0000119 MGI:4834177 NCBI chr12:28,699,600...28,709,591
Ensembl chr12:28,699,601...28,709,588 		JBrowse link
G Rnaseh2a ribonuclease H2, large subunit enables ISO
IBA
ISS		 MGI
GO_Central
UniProt		 GO_REF:0000024 GO_REF:0000033 GO_REF:0000119 MGI:4834177 NCBI chr 8:85,683,239...85,694,498
Ensembl chr 8:85,683,239...85,696,396 		JBrowse link
tRNA-intron endonuclease activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tsen2 tRNA splicing endonuclease subunit 2 enables IBA GO_Central GO_REF:0000033 NCBI chr 6:115,521,652...115,555,297
Ensembl chr 6:115,521,625...115,555,589 		JBrowse link
G Tsen34 tRNA splicing endonuclease subunit 34 enables IBA GO_Central GO_REF:0000033 NCBI chr 7:3,696,300...3,704,033
Ensembl chr 7:3,695,862...3,704,023 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 28853
    catalytic activity 5741
      catalytic activity, acting on a nucleic acid 618
        catalytic activity, acting on RNA 398
          RNA nuclease activity 139
            RNA endonuclease activity 68
              RNA endonuclease activity, producing 3'-phosphomonoesters + 6
              RNA endonuclease activity, producing 5'-phosphomonoesters + 29
              ribonuclease MRP activity 2
              ribonuclease T2 activity 2
Path 2
Term Annotations click to browse term
  molecular_function 28853
    catalytic activity 5741
      hydrolase activity 2470
        hydrolase activity, acting on ester bonds 790
          nuclease activity 226
            endonuclease activity 127
              RNA endonuclease activity 68
                RNA endonuclease activity, producing 3'-phosphomonoesters + 6
                RNA endonuclease activity, producing 5'-phosphomonoesters + 29
                ribonuclease MRP activity 2
                ribonuclease T2 activity 2
paths to the root