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ONTOLOGY REPORT - ANNOTATIONS

Term:RNA endonuclease activity
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Accession:GO:0004521 term browser browse the term
Definition:Catalysis of the hydrolysis of ester linkages within ribonucleic acid by creating internal breaks.
Synonyms:exact_synonym: endoribonuclease activity
 related_synonym: endonuclease G activity
 xref: Reactome:R-HSA-9708327 "ANG cleaves tRNA to yield tRNA halves";   Reactome:R-HSA-9708812 "ELAC2 cleaves pre-tRNA to yield 3' trailer (type II tRF or tRF-1)";   reactome:R-HSA-425923 "IRE1alpha hydrolyzes Xbp1 mRNA and Xbp1 mRNA is spliced";   reactome:R-HSA-426520 "Endonucleolytic RISC hydrolyzes target RNAs";   reactome:R-HSA-5601887 "PLD6 dimer cleaves primary piRNA transcript to pre-piRNA";   reactome:R-HSA-5601910 "Complexed PIWIL2:2'-O-methyl-piRNA cleaves transposon RNA";   reactome:R-HSA-6791223 "18SE pre-rRNA in pre-40S particles is nucleolytically processed during translocation from the nucleus to the cytosol";   reactome:R-HSA-6814555 "Integrator complex processes the 3' end of snRNA";   reactome:R-HSA-9009936 "RNASEL cleaves cellular ssRNA";   reactome:R-HSA-9009941 "RNASEL cleaves viral ssRNA";   reactome:R-HSA-9023909 "C3PO hydrolyzes cleaved passenger strand";   reactome:R-HSA-9023912 "AGO2 cleaves passenger strand of duplex siRNA";   reactome:R-HSA-927836 "SMG6 hydrolyzes mRNA with premature termination codon"


show annotations for term's descendants           Sort by:
RNA endonuclease activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AGO1 argonaute RISC component 1 NOT|enables IDA (PMID:23809764) UniProt PMID:23809764 NCBI chr 1:35,869,761...35,930,532
Ensembl chr 1:35,869,808...35,930,532 		JBrowse link
G AGO2 argonaute RISC catalytic component 2 enables IDA
IBA
IEA
TAS		 (PMID:18178619) BHF-UCL
GO_Central
Ensembl
Reactome		 PMID:18178619 GO_REF:0000033 GO_REF:0000107 Reactome:R-HSA-426520 NCBI chr 8:140,520,156...140,642,313
Ensembl chr 8:140,520,156...140,635,633 		JBrowse link
G AGO3 argonaute RISC catalytic component 3 enables IMP
IBA		 (PMID:29040713) UniProt
GO_Central		 PMID:29040713 GO_REF:0000033 NCBI chr 1:35,930,718...36,072,500
Ensembl chr 1:35,930,718...36,072,500 		JBrowse link
G AGO4 argonaute RISC component 4 enables IBA GO_Central GO_REF:0000033 NCBI chr 1:35,807,636...35,857,890
Ensembl chr 1:35,808,016...35,857,890 		JBrowse link
G ANG angiogenin enables TAS Reactome Reactome:R-HSA-9708327 NCBI chr14:20,684,177...20,694,186
Ensembl chr14:20,684,177...20,698,971 		JBrowse link
G ANKZF1 ankyrin repeat and zinc finger peptidyl tRNA hydrolase 1 enables IDA (PMID:30244831), (PMID:31011209) UniProt PMID:30244831 PMID:31011209 NCBI chr 2:219,229,806...219,236,679
Ensembl chr 2:219,229,783...219,236,679 		JBrowse link
G APEX1 apurinic/apyrimidinic endodeoxyribonuclease 1 ISO RGD PMID:19401441 RGD:2315668 NCBI chr14:20,455,226...20,457,767
Ensembl chr14:20,455,191...20,457,772 		JBrowse link
G CPSF3 cleavage and polyadenylation specific factor 3 enables IMP
IBA
ISS
IEA		 (PMID:30507380) UniProt
GO_Central
Ensembl		 PMID:30507380 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr 2:9,423,654...9,473,101
Ensembl chr 2:9,423,651...9,473,101 		JBrowse link
G DICER1 dicer 1, ribonuclease III enables IDA
TAS
IMP		 (PMID:25549615)
(PMID:19820710)
(PMID:18325616), (PMID:19701182)		 BHF-UCL
AgBase		 PMID:18325616 PMID:19701182 PMID:19820710 PMID:25549615 NCBI chr14:95,086,228...95,158,010
Ensembl chr14:95,086,228...95,158,010 		JBrowse link
G DROSHA drosha ribonuclease III enables IEA Ensembl
UniProt		 GO_REF:0000107 GO_REF:0000117 NCBI chr 5:31,400,494...31,532,093
Ensembl chr 5:31,400,494...31,532,196 		JBrowse link
G ELAC2 elaC ribonuclease Z 2 enables TAS Reactome Reactome:R-HSA-9708812 NCBI chr17:12,991,612...13,018,027
Ensembl chr17:12,991,612...13,018,065 		JBrowse link
G ENDOG endonuclease G enables IBA GO_Central GO_REF:0000033 NCBI chr 9:128,818,500...128,822,676
Ensembl chr 9:128,818,500...128,822,676 		JBrowse link
G ENDOU endonuclease, poly(U) specific enables IDA
IBA
IGI
IEA		 (PMID:18936097)
(PMID:37803019)		 UniProt
GO_Central
FlyBase
InterPro		 PMID:18936097 PMID:37803019 GO_REF:0000002 GO_REF:0000033 NCBI chr12:47,709,734...47,725,490
Ensembl chr12:47,709,734...47,725,567 		JBrowse link
G ERN1 endoplasmic reticulum to nucleus signaling 1 enables IEA
IBA
IDA		 (PMID:11779465), (PMID:19328063), (PMID:21317875), (PMID:9637683) InterPro
GO_Central
UniProt
Ensembl		 PMID:9637683 PMID:11779465 PMID:19328063 PMID:21317875 GO_REF:0000002 GO_REF:0000033 GO_REF:0000107 NCBI chr17:64,039,142...64,130,144
Ensembl chr17:64,039,080...64,130,819 		JBrowse link
G ERN2 endoplasmic reticulum to nucleus signaling 2 enables IEA
IBA		 InterPro
GO_Central		 GO_REF:0000002 GO_REF:0000033 NCBI chr16:23,690,310...23,713,222
Ensembl chr16:23,690,310...23,713,226 		JBrowse link
G EXOG exo/endonuclease G enables IBA GO_Central GO_REF:0000033 NCBI chr 3:38,496,340...38,526,303
Ensembl chr 3:38,496,127...38,542,161 		JBrowse link
G INTS11 integrator complex subunit 11 enables IMP
IBA		 (PMID:16239144) FlyBase
GO_Central		 PMID:16239144 GO_REF:0000033 NCBI chr 1:1,311,600...1,324,660
Ensembl chr 1:1,311,585...1,324,687 		JBrowse link
G KHNYN KH and NYN domain containing enables IBA GO_Central GO_REF:0000033 NCBI chr14:24,423,165...24,441,843
Ensembl chr14:24,429,286...24,441,843 		JBrowse link
G LACTB2 lactamase beta 2 enables IDA
IBA		 (PMID:26826708) UniProt
GO_Central		 PMID:26826708 GO_REF:0000033 NCBI chr 8:70,637,266...70,669,185
Ensembl chr 8:70,635,318...70,669,185 		JBrowse link
G MBLAC1 metallo-beta-lactamase domain containing 1 enables IMP (PMID:30507380) UniProt PMID:30507380 NCBI chr 7:100,126,967...100,128,495
Ensembl chr 7:100,126,785...100,128,495 		JBrowse link
G NOB1 NIN1 (RPN12) binding protein 1 homolog enables IEA
IBA
EXP		 (PMID:23439679), (PMID:23482395) InterPro
GO_Central
UniProt
Reactome		 PMID:23439679 PMID:23482395 GO_REF:0000002 GO_REF:0000033 GO_REF:0000104 NCBI chr16:69,741,871...69,754,926
Ensembl chr16:69,741,871...69,754,926 		JBrowse link
G NYNRIN NYN domain and retroviral integrase containing enables IBA GO_Central GO_REF:0000033 NCBI chr14:24,399,003...24,419,283
Ensembl chr14:24,399,003...24,419,283 		JBrowse link
G PIWIL1 piwi like RNA-mediated gene silencing 1 enables ISS
IBA
IEA		 UniProt
GO_Central
Ensembl		 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr12:130,337,887...130,426,260
Ensembl chr12:130,337,887...130,372,637 		JBrowse link
G PIWIL2 piwi like RNA-mediated gene silencing 2 enables ISS
IBA
IEA		 UniProt
GO_Central
Ensembl		 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr 8:22,275,316...22,357,568
Ensembl chr 8:22,275,316...22,357,568 		JBrowse link
G PIWIL3 piwi like RNA-mediated gene silencing 3 enables IBA GO_Central GO_REF:0000033 NCBI chr22:24,719,034...24,774,720
Ensembl chr22:24,719,034...24,774,720 		JBrowse link
G PIWIL4 piwi like RNA-mediated gene silencing 4 NOT|enables ISS
IBA		 UniProt
GO_Central		 GO_REF:0000024 GO_REF:0000033 NCBI chr11:94,567,368...94,621,421
Ensembl chr11:94,543,840...94,621,421 		JBrowse link
G RCL1 RNA terminal phosphate cyclase like 1 enables IBA GO_Central GO_REF:0000033 NCBI chr 9:4,792,944...4,861,066
Ensembl chr 9:4,792,944...4,885,917 		JBrowse link
G RNASEK ribonuclease K enables IEA
IBA
IDA		 (PMID:17881363) InterPro
GO_Central
UniProt		 PMID:17881363 GO_REF:0000002 GO_REF:0000033 NCBI chr17:7,012,624...7,014,532
Ensembl chr17:7,012,417...7,014,532 		JBrowse link
G RNASEL ribonuclease L enables NAS (PMID:7514601) UniProt PMID:7514601 NCBI chr 1:182,573,634...182,589,256
Ensembl chr 1:182,573,634...182,589,256 		JBrowse link
G RNASET2 ribonuclease T2 enables IBA GO_Central GO_REF:0000033 NCBI chr 6:166,922,113...166,956,550
Ensembl chr 6:166,922,113...166,957,191 		JBrowse link
G SLFN11 schlafen family member 11 enables ISO PMID:29563550 UniProt PMID:29563550 RGD:13601999 NCBI chr17:35,350,305...35,373,621
Ensembl chr17:35,350,305...35,373,701 		JBrowse link
G SLFN13 schlafen family member 13 enables IDA (PMID:29563550) UniProt PMID:29563550 NCBI chr17:35,435,096...35,449,766
Ensembl chr17:35,435,096...35,448,837 		JBrowse link
G SLFN14 schlafen family member 14 enables IEA
IBA
IDA		 (PMID:25996083) Ensembl
GO_Central
UniProt		 PMID:25996083 GO_REF:0000033 GO_REF:0000107 NCBI chr17:35,543,985...35,560,819
Ensembl chr17:35,543,985...35,560,819 		JBrowse link
G SMG6 SMG6 nonsense mediated mRNA decay factor enables IMP
TAS
IDA		 (PMID:18974281)
(PMID:19060897)		 UniProt
Reactome		 PMID:18974281 PMID:19060897 Reactome:R-HSA-927836 NCBI chr17:2,059,839...2,303,785
Ensembl chr17:2,059,839...2,303,785 		JBrowse link
G SND1 staphylococcal nuclease and tudor domain containing 1 enables IDA
IEA		 (PMID:28546213) UniProt PMID:28546213 GO_REF:0000104 NCBI chr 7:127,652,194...128,092,593
Ensembl chr 7:127,652,194...128,092,609 		JBrowse link
G TSNAX translin associated factor X enables IBA GO_Central GO_REF:0000033 NCBI chr 1:231,528,669...231,566,524
Ensembl chr 1:231,528,541...231,566,524 		JBrowse link
G YBEY ybeY metalloendoribonuclease enables IDA (PMID:28153719) UniProt PMID:28153719 NCBI chr21:46,286,342...46,313,225
Ensembl chr21:46,286,342...46,297,751 		JBrowse link
G ZC3H12A zinc finger CCCH-type containing 12A enables IEA
IBA
ISS		 Ensembl
GO_Central
UniProt		 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr 1:37,474,580...37,484,377
Ensembl chr 1:37,474,580...37,484,377 		JBrowse link
G ZC3H12B zinc finger CCCH-type containing 12B enables IBA GO_Central GO_REF:0000033 NCBI chr  X:65,034,826...65,507,887
Ensembl chr  X:65,034,788...65,507,887 		JBrowse link
G ZC3H12C zinc finger CCCH-type containing 12C enables IBA GO_Central GO_REF:0000033 NCBI chr11:110,093,392...110,171,841
Ensembl chr11:110,093,392...110,171,841 		JBrowse link
G ZC3H12D zinc finger CCCH-type containing 12D enables IBA GO_Central GO_REF:0000033 NCBI chr 6:149,446,795...149,485,014
Ensembl chr 6:149,446,795...149,485,014 		JBrowse link
3'-tRNA processing endoribonuclease activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ELAC1 elaC ribonuclease Z 1 enables IEA
IBA		 UniProt
GO_Central		 GO_REF:0000003 GO_REF:0000033 NCBI chr18:50,968,040...50,988,121
Ensembl chr18:50,967,991...50,988,121 		JBrowse link
G ELAC2 elaC ribonuclease Z 2 enables IEA
IBA		 UniProt
GO_Central
InterPro		 GO_REF:0000002 GO_REF:0000003 GO_REF:0000033 NCBI chr17:12,991,612...13,018,027
Ensembl chr17:12,991,612...13,018,065 		JBrowse link
endoribonuclease activity, cleaving miRNA-paired mRNA term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AGO2 argonaute RISC catalytic component 2 enables IMP
IDA		 (PMID:22795694)
(PMID:15260970)		 BHF-UCL PMID:15260970 PMID:22795694 NCBI chr 8:140,520,156...140,642,313
Ensembl chr 8:140,520,156...140,635,633 		JBrowse link
G AGO3 argonaute RISC catalytic component 3 enables IMP (PMID:29040713) UniProt PMID:29040713 NCBI chr 1:35,930,718...36,072,500
Ensembl chr 1:35,930,718...36,072,500 		JBrowse link
endoribonuclease activity, cleaving siRNA-paired mRNA term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AGO2 argonaute RISC catalytic component 2 enables IDA
IEA		 (PMID:15260970), (PMID:17524464) BHF-UCL
InterPro		 PMID:15260970 PMID:17524464 GO_REF:0000002 NCBI chr 8:140,520,156...140,642,313
Ensembl chr 8:140,520,156...140,635,633 		JBrowse link
phosphodiesterase decapping endonuclease activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NUDT12 nudix hydrolase 12 enables IMP (PMID:31875550) UniProt PMID:31875550 NCBI chr 5:103,548,855...103,562,789
Ensembl chr 5:103,548,855...103,562,790 		JBrowse link
G NUDT16 nudix hydrolase 16 enables IDA
IBA		 (PMID:29483298) UniProt
GO_Central		 PMID:29483298 GO_REF:0000033 NCBI chr 3:131,381,671...131,388,830
Ensembl chr 3:131,381,671...131,388,830 		JBrowse link
G NUDT16L1 nudix hydrolase 16 like 1 NOT|enables IBA GO_Central GO_REF:0000033 NCBI chr16:4,693,562...4,695,859
Ensembl chr16:4,693,562...4,695,859 		JBrowse link
ribonuclease A activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G RNASE1 ribonuclease A family member 1, pancreatic enables TAS
IEA		 (PMID:8049276) PINC
UniProt		 PMID:8049276 GO_REF:0000003 NCBI chr14:20,801,228...20,802,844
Ensembl chr14:20,801,228...20,802,855 		JBrowse link
G RNASE2 ribonuclease A family member 2 enables IEA UniProt GO_REF:0000003 NCBI chr14:20,955,487...20,956,436
Ensembl chr14:20,955,487...20,956,436 		JBrowse link
G RNASE4 ribonuclease A family member 4 enables NAS (PMID:7742370) UniProt PMID:7742370 NCBI chr14:20,684,560...20,701,216
Ensembl chr14:20,684,560...20,701,216 		JBrowse link
G RNASE8 ribonuclease A family member 8 enables IDA (PMID:11861908) UniProt PMID:11861908 NCBI chr14:21,057,822...21,058,455
Ensembl chr14:21,057,822...21,058,455 		JBrowse link
ribonuclease III activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DICER1 dicer 1, ribonuclease III enables IDA
IBA
IEA
TAS
EXP		 (PMID:21753850)
(PMID:12411504), (PMID:12411505)		 BHF-UCL
GO_Central
InterPro
Reactome
UniProt		 PMID:12411504 PMID:12411505 PMID:21753850 GO_REF:0000002 GO_REF:0000003 GO_REF:0000033 Reactome:R-HSA-9708408 NCBI chr14:95,086,228...95,158,010
Ensembl chr14:95,086,228...95,158,010 		JBrowse link
G DROSHA drosha ribonuclease III enables IDA
IBA
IEA		 (PMID:14508493), (PMID:15574589) WB
GO_Central
InterPro
UniProt		 PMID:14508493 PMID:15574589 GO_REF:0000002 GO_REF:0000003 GO_REF:0000033 NCBI chr 5:31,400,494...31,532,093
Ensembl chr 5:31,400,494...31,532,196 		JBrowse link
G MRPL44 mitochondrial ribosomal protein L44 NOT|enables IKR (PMID:11551941) FlyBase PMID:11551941 NCBI chr 2:223,950,854...223,967,714
Ensembl chr 2:223,957,463...223,967,714 		JBrowse link
ribonuclease MRP activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G RMRP RNA component of mitochondrial RNA processing endoribonuclease enables IEA RNAcentral GO_REF:0000115 NCBI chr 9:35,657,750...35,658,019
Ensembl chr 9:35,657,754...35,658,017 		JBrowse link
G RPP40 ribonuclease P/MRP subunit p40 contributes_to IBA GO_Central GO_REF:0000033 NCBI chr 6:4,988,426...5,004,037
Ensembl chr 6:4,994,717...5,004,063 		JBrowse link
ribonuclease P activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G POP1 POP1 homolog, ribonuclease P/MRP subunit contributes_to
enables		 IDA
IEA		 (PMID:30454648), (PMID:8918471) UniProt PMID:8918471 PMID:30454648 GO_REF:0000003 NCBI chr 8:98,117,293...98,159,835
Ensembl chr 8:98,117,293...98,159,835 		JBrowse link
G POP4 POP4 homolog, ribonuclease P/MRP subunit enables
contributes_to		 IEA
IDA		 (PMID:30454648) UniProt PMID:30454648 GO_REF:0000003 NCBI chr19:29,606,283...29,617,237
Ensembl chr19:29,606,283...29,617,237 		JBrowse link
G POP5 POP5 homolog, ribonuclease P/MRP subunit contributes_to
enables		 IDA
IEA		 (PMID:30454648) UniProt
Ensembl		 PMID:30454648 GO_REF:0000003 GO_REF:0000107 NCBI chr12:120,578,764...120,581,402
Ensembl chr12:120,578,764...120,581,402 		JBrowse link
G POP7 POP7 homolog, ribonuclease P/MRP subunit enables
contributes_to		 IEA
IDA		 (PMID:30454648) UniProt PMID:30454648 GO_REF:0000003 NCBI chr 7:100,706,121...100,707,486
Ensembl chr 7:100,706,121...100,707,486 		JBrowse link
G PRORP protein only RNase P catalytic subunit enables IDA
IBA
IEA		 (PMID:25953853) UniProt
GO_Central		 PMID:25953853 GO_REF:0000003 GO_REF:0000033 NCBI chr14:35,121,839...35,277,622
Ensembl chr14:35,121,846...35,277,622 		JBrowse link
G RPP14 ribonuclease P/MRP subunit p14 enables
contributes_to		 IEA
IDA		 (PMID:30454648) UniProt PMID:30454648 GO_REF:0000003 NCBI chr 3:58,306,245...58,320,193
Ensembl chr 3:58,306,245...58,324,695 		JBrowse link
G RPP21 ribonuclease P/MRP subunit p21 enables
contributes_to		 IEA
IDA		 (PMID:30454648) UniProt PMID:30454648 GO_REF:0000003 NCBI chr 6:30,345,156...30,346,857
Ensembl chr 6:30,345,131...30,346,884 		JBrowse link
G RPP25 ribonuclease P and MRP subunit p25 contributes_to
enables		 IDA
IEA		 (PMID:30454648) UniProt PMID:30454648 GO_REF:0000003 NCBI chr15:74,954,418...74,956,772
Ensembl chr15:74,954,418...74,956,772 		JBrowse link
G RPP30 ribonuclease P/MRP subunit p30 enables
contributes_to		 TAS
IEA
IDA		 (PMID:9630247)
(PMID:30454648)		 PINC
UniProt		 PMID:9630247 PMID:30454648 GO_REF:0000003 NCBI chr10:90,871,974...90,908,556
Ensembl chr10:90,871,952...90,908,553 		JBrowse link
G RPP38 ribonuclease P/MRP subunit p38 enables
contributes_to		 IEA
IBA
IDA		 (PMID:30454648) UniProt
GO_Central		 PMID:30454648 GO_REF:0000003 GO_REF:0000033 NCBI chr10:15,097,355...15,104,257
Ensembl chr10:15,097,180...15,139,818 		JBrowse link
G RPP40 ribonuclease P/MRP subunit p40 enables
contributes_to		 IEA
IBA
TAS
IDA		 (PMID:9630247)
(PMID:30454648)		 UniProt
GO_Central
PINC		 PMID:9630247 PMID:30454648 GO_REF:0000003 GO_REF:0000033 NCBI chr 6:4,988,426...5,004,037
Ensembl chr 6:4,994,717...5,004,063 		JBrowse link
G RPPH1 ribonuclease P RNA component H1 enables IEA RNAcentral GO_REF:0000115 NCBI chr14:20,343,071...20,343,411
Ensembl chr14:20,343,075...20,343,407 		JBrowse link
ribonuclease T2 activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AL159163.1 novel protein enables IEA InterPro GO_REF:0000002 Ensembl chr 6:166,858,094...166,956,124 JBrowse link
G RNASET2 ribonuclease T2 enables IEA InterPro
UniProt		 GO_REF:0000002 GO_REF:0000003 NCBI chr 6:166,922,113...166,956,550
Ensembl chr 6:166,922,113...166,957,191 		JBrowse link
RNA endonuclease activity, producing 3'-phosphomonoesters term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G RIDA reactive intermediate imine deaminase A homolog enables ISO
ISS		 RGD
UniProt		 PMID:10400702 GO_REF:0000024 RGD:9685547 NCBI chr 8:98,102,344...98,117,171
Ensembl chr 8:98,102,344...98,117,171 		JBrowse link
RNA endonuclease activity, producing 5'-phosphomonoesters term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AGO2 argonaute RISC catalytic component 2 enables IEA UniProt GO_REF:0000104 NCBI chr 8:140,520,156...140,642,313
Ensembl chr 8:140,520,156...140,635,633 		JBrowse link
G DICER1 dicer 1, ribonuclease III enables IEA InterPro GO_REF:0000002 NCBI chr14:95,086,228...95,158,010
Ensembl chr14:95,086,228...95,158,010 		JBrowse link
G ELAC1 elaC ribonuclease Z 1 enables IEA InterPro GO_REF:0000002 NCBI chr18:50,968,040...50,988,121
Ensembl chr18:50,967,991...50,988,121 		JBrowse link
G ENDOV endonuclease V enables IDA
IBA		 (PMID:23912683), (PMID:23912718), (PMID:27573237), (PMID:3170309) UniProt
GO_Central		 PMID:3170309 PMID:23912683 PMID:23912718 PMID:27573237 GO_REF:0000033 NCBI chr17:80,415,167...80,438,086
Ensembl chr17:80,415,165...80,438,086 		JBrowse link
G PLD6 phospholipase D family member 6 enables IBA GO_Central GO_REF:0000033 NCBI chr17:17,200,995...17,206,333
Ensembl chr17:17,200,995...17,206,333 		JBrowse link
RNA lariat debranching enzyme activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DBR1 debranching RNA lariats 1 enables IEA
IBA
IMP		 (PMID:10982890), (PMID:29474921) Ensembl
GO_Central
UniProt		 PMID:10982890 PMID:29474921 GO_REF:0000033 GO_REF:0000107 GO_REF:0000117 NCBI chr 3:138,160,988...138,174,921
Ensembl chr 3:138,160,988...138,174,949 		JBrowse link
RNA-DNA hybrid ribonuclease activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APEX1 apurinic/apyrimidinic endodeoxyribonuclease 1 enables TAS (PMID:11286553) UniProt PMID:11286553 NCBI chr14:20,455,226...20,457,767
Ensembl chr14:20,455,191...20,457,772 		JBrowse link
G ERVK-6 endogenous retrovirus group K member 6, envelope enables IEA UniProt
InterPro		 GO_REF:0000002 GO_REF:0000003
G ERVK-7 endogenous retrovirus group K member 7 enables IEA UniProt
InterPro		 GO_REF:0000002 GO_REF:0000003
G EXO1 exonuclease 1 enables TAS (PMID:10364235) PINC PMID:10364235 NCBI chr 1:241,847,986...241,889,939
Ensembl chr 1:241,847,967...241,895,148 		JBrowse link
G FEN1 flap structure-specific endonuclease 1 enables IDA
IBA		 (PMID:7961795) UniProt
GO_Central		 PMID:7961795 GO_REF:0000033 NCBI chr11:61,792,911...61,797,238
Ensembl chr11:61,792,911...61,797,238 		JBrowse link
G NYNRIN NYN domain and retroviral integrase containing enables IEA InterPro GO_REF:0000002 NCBI chr14:24,399,003...24,419,283
Ensembl chr14:24,399,003...24,419,283 		JBrowse link
G RNASEH1 ribonuclease H1 enables IDA
IBA
IEA		 (PMID:21700224) UniProt
GO_Central
InterPro		 PMID:21700224 GO_REF:0000002 GO_REF:0000003 GO_REF:0000033 GO_REF:0000104 GO_REF:0000117 NCBI chr 2:3,531,813...3,558,333
Ensembl chr 2:3,541,430...3,558,333 		JBrowse link
G RNASEH2A ribonuclease H2 subunit A enables IEA
IBA
IDA		 (PMID:21177858) UniProt
GO_Central
InterPro		 PMID:21177858 GO_REF:0000002 GO_REF:0000003 GO_REF:0000033 GO_REF:0000104 NCBI chr19:12,806,584...12,813,640
Ensembl chr19:12,806,584...12,813,640 		JBrowse link
G UBXN8 UBX domain protein 8 enables IEA InterPro GO_REF:0000002 NCBI chr 8:30,729,135...30,767,006
Ensembl chr 8:30,729,131...30,767,006 		JBrowse link
tRNA-intron endonuclease activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TSEN2 tRNA splicing endonuclease subunit 2 enables IEA
IBA		 InterPro
GO_Central
UniProt		 GO_REF:0000002 GO_REF:0000003 GO_REF:0000033 GO_REF:0000104 NCBI chr 3:12,480,231...12,539,624
Ensembl chr 3:12,484,421...12,541,549 		JBrowse link
G TSEN34 tRNA splicing endonuclease subunit 34 enables IEA
IBA		 InterPro
GO_Central
UniProt		 GO_REF:0000002 GO_REF:0000003 GO_REF:0000033 GO_REF:0000104 NCBI chr19:54,189,441...54,194,532
Ensembl chr19:54,189,938...54,194,536 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 19587
    catalytic activity 6011
      catalytic activity, acting on a nucleic acid 653
        catalytic activity, acting on RNA 419
          RNA nuclease activity 134
            RNA endonuclease activity 77
              RNA endonuclease activity, producing 3'-phosphomonoesters + 7
              RNA endonuclease activity, producing 5'-phosphomonoesters + 34
              ribonuclease MRP activity 2
              ribonuclease T2 activity 2
Path 2
Term Annotations click to browse term
  molecular_function 19587
    catalytic activity 6011
      hydrolase activity 2631
        hydrolase activity, acting on ester bonds 840
          nuclease activity 251
            endonuclease activity 138
              RNA endonuclease activity 77
                RNA endonuclease activity, producing 3'-phosphomonoesters + 7
                RNA endonuclease activity, producing 5'-phosphomonoesters + 34
                ribonuclease MRP activity 2
                ribonuclease T2 activity 2
paths to the root