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ONTOLOGY REPORT - ANNOTATIONS

Term:methionyl-tRNA formyltransferase activity
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Accession:GO:0004479 term browser browse the term
Definition:Catalysis of the reaction: 10-formyltetrahydrofolate + L-methionyl-tRNA + H2O = tetrahydrofolate + N-formylmethionyl-tRNA.
Synonyms:related_synonym: 10-formyltetrahydrofolate:L-methionyl-tRNA N-formyltransferase activity;   N(10)-formyltetrahydrofolic-methionyl-transfer ribonucleic transformylase activity;   N-terminal peptidyl-methionine N-formylation;   N10-formyltetrahydrofolic-methionyl-transfer ribonucleic transformylase activity;   conversion of met-tRNAf to fmet-tRNA;   conversion of mitochondrial met-tRNAf to fmet-tRNA;   formylmethionyl-transfer ribonucleic synthetase activity;   methionyl ribonucleic formyltransferase activity;   methionyl-tRNA Met formyltransferase activity;   methionyl-tRNA transformylase activity;   methionyl-transfer RNA transformylase activity;   methionyl-transfer ribonucleate methyltransferase activity;   methionyl-transfer ribonucleic transformylase activity;   mitochondrial N-terminal peptidyl-methionine N-formylation
 alt_id: GO:0001718;   GO:0070128
 xref: EC:2.1.2.9;   MetaCyc:METHIONYL-TRNA-FORMYLTRANSFERASE-RXN;   RHEA:24380;   reactome:R-HSA-5389841 "MTFMT formylates methionyl-tRNA"


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methionyl-tRNA formyltransferase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mtfmt mitochondrial methionyl-tRNA formyltransferase enables ISO
ISS
IEA
IBA		 (PMID:25288793)
GO_REF:0000024
GO_REF:0000107
GO_REF:0000033		 RGD
UniProt
Ensembl
GO_Central		 PMID:25288793 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr 8:74,848,936...74,866,987
Ensembl chr 8:65,953,767...65,971,841 		JBrowse link
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  molecular_function 21090
    catalytic activity 6125
      catalytic activity, acting on a nucleic acid 632
        catalytic activity, acting on RNA 391
          catalytic activity, acting on a tRNA 136
            methionyl-tRNA formyltransferase activity 1
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