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ONTOLOGY REPORT - ANNOTATIONS

Term:lactoylglutathione lyase activity
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Accession:GO:0004462 term browser browse the term
Definition:Catalysis of the reaction: (R)-S-lactoylglutathione = glutathione + methylglyoxal.
Synonyms:related_synonym: (R)-S-lactoylglutathione methylglyoxal-lyase (isomerizing) activity;   (R)-S-lactoylglutathione methylglyoxal-lyase (isomerizing; glutathione-forming);   aldoketomutase activity;   glyoxalase I activity;   glyoxylase I;   ketone-aldehyde mutase activity;   methylglyoxalase activity
 xref: EC:4.4.1.5;   KEGG_REACTION:R02530;   MetaCyc:GLYOXI-RXN;   RHEA:19069;   reactome:R-HSA-5694071 "GLO1 dimer:2xZn2+ transforms MGXL and GSH to (R)-S-LGSH"


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lactoylglutathione lyase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BTBD9 BTB domain containing 9 enables IEA UniProt GO_REF:0000003 NCBI chr 7:33,723,077...34,122,673
Ensembl chr 7:33,720,014...34,124,458 		JBrowse link
G GLO1 glyoxalase I enables ISO
IEA		 RGD
UniProt
InterPro
Ensembl		 PMID:8719777 PMID:8903102 PMID:10712823 GO_REF:0000002 GO_REF:0000104 GO_REF:0000107 RGD:1627641 RGD:1641958 RGD:1641959 NCBI chr 7:34,156,194...34,183,560
Ensembl chr 7:34,157,535...34,183,528 		JBrowse link
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  molecular_function 18689
    catalytic activity 5662
      lyase activity 202
        carbon-sulfur lyase activity 15
          lactoylglutathione lyase activity 2
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