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ONTOLOGY REPORT - ANNOTATIONS

Term:glutamate decarboxylase activity
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Accession:GO:0004351 term browser browse the term
Definition:Catalysis of the reaction: L-glutamate = 4-aminobutanoate + CO2.
Synonyms:broad_synonym: aspartic alpha-decarboxylase
 related_synonym: L-aspartate-alpha-decarboxylase activity;   L-glutamate 1-carboxy-lyase (4-aminobutanoate-forming);   L-glutamate 1-carboxy-lyase activity;   L-glutamate alpha-decarboxylase activity;   L-glutamic acid decarboxylase activity;   L-glutamic decarboxylase activity;   cysteic acid decarboxylase activity;   gamma-glutamate decarboxylase activity
 xref: EC:4.1.1.15;   MetaCyc:GLUTDECARBOX-RXN;   RHEA:17785;   Reactome:R-HSA-888572 "PXLP-K405-GAD1 decarboxylates L-Glu to form GABA";   reactome:R-HSA-888577 "Synthesis of GABA by GAD2"


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glutamate decarboxylase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gad1 glutamate decarboxylase 1 enables IDA
ISS
ISO
IEA
IBA		 GO_REF:0000024
PMID:1924335
(PMID:10671565), (PMID:17384644)
(MGI:892697|PMID:9177246)
GO_REF:0000107
GO_REF:0000033		 UniProt
RGD
Ensembl
GO_Central		 PMID:9177246 PMID:10671565 PMID:17384644 PMID:1924335 PMID:17712632 More... GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 MGI:892697, RGD:728511, RGD:6480258, RGD:6480261, RGD:728511 NCBI chr 3:55,369,704...55,410,335
Ensembl chr 3:55,369,704...55,410,333 		JBrowse link
G Gad2 glutamate decarboxylase 2 enables IDA
IBA		 GO_REF:0000033 GO_Central
RGD		 PMID:8999827 PMID:10812196 GO_REF:0000033, RGD:1625237, RGD:6480261 NCBI chr17:84,763,630...84,826,155
Ensembl chr17:84,763,628...84,826,155 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 21010
    catalytic activity 6145
      lyase activity 212
        carbon-carbon lyase activity 53
          carboxy-lyase activity 33
            glutamate decarboxylase activity 2
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