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Term:glucose-6-phosphate dehydrogenase activity
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Accession:GO:0004345 term browser browse the term
Definition:Catalysis of the reaction: D-glucose 6-phosphate + NADP+ = D-glucono-1,5-lactone 6-phosphate + NADPH + H+.
Synonyms:exact_synonym: 6-phosphoglucose dehydrogenase activity;   D-glucose 6-phosphate dehydrogenase activity;   G6PDH;   NADP-dependent glucose 6-phosphate dehydrogenase activity;   NADP-glucose-6-phosphate dehydrogenase activity;   glucose-6-phosphate 1-dehydrogenase activity
 related_synonym: 6-phosphoglucose dehydrogenas;   D-glucose-6-phosphate:NADP+ 1-oxidoreductase activity;   Entner-doudoroff enzyme;   G6PD activity;   GDH;   zwischenferment
 xref: EC:;   MetaCyc:GLU6PDEHYDROG-RXN;   RHEA:15841;   reactome:R-HSA-70377 "alpha-D-glucose 6-phosphate + NADP+ => D-glucono-1,5-lactone 6-phosphate + NADPH + H+"

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glucose-6-phosphate dehydrogenase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G G6pd glucose-6-phosphate dehydrogenase enables IDA
MGI:2182739|MGI:2387672 (MGI:1097071|PMID:9330624), (MGI:1202104|PMID:9539108), (MGI:1261671|PMID:9627357), (MGI:1349468|PMID:3377761), (MGI:2387959|PMID:10627286), (MGI:2387962|PMID:7489710), (MGI:2449252|PMID:12521604), (MGI:3054313|PMID:15155459), (MGI:3522057|PMID:15271799), (MGI:3527298|PMID:14751857), (MGI:3607389|PMID:14757696), (MGI:3694178|PMID:15998684), (MGI:49164|PMID:1953691), (MGI:53579|PMID:5764873), (MGI:54095|PMID:943046), (MGI:54902|PMID:7439685), (MGI:58177|PMID:3243423), (MGI:61105|PMID:8491670), (MGI:85983|PMID:9067418), (MGI:87492|PMID:9169132)
(PMID:15858258), (PMID:2420826), (PMID:5643703), (PMID:743300)
RGD PMID:743300 PMID:943046 PMID:1953691 PMID:2420826 PMID:3243423 More... MGI:1097071 MGI:1202104 MGI:1261671 MGI:1349468 MGI:2387959 MGI:2387962 MGI:2449252 MGI:3054313 MGI:3522057 MGI:3527298 MGI:3607389 MGI:3694178 MGI:49164 MGI:53579 MGI:54095 MGI:54902 MGI:58177 MGI:61105 MGI:85983 MGI:87492, RGD:1599371, RGD:10047183, RGD:10047267, RGD:2317316, RGD:2317315, RGD:1599574, RGD:1624966, RGD:1624987 NCBI chr  X:152,201,081...152,220,863
Ensembl chr  X:152,201,098...152,220,801
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G H6pd hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase) enables IDA
(PMID:18628520), (PMID:23132696)
MGI:3624665 (MGI:2668276|PMID:12831846), (MGI:3793398|PMID:18222920)
RGD PMID:12831846 PMID:18222920 PMID:18628520 PMID:23132696 PMID:6813321 MGI:2668276 MGI:3793398, RGD:1641956 NCBI chr 5:160,434,499...160,470,203
Ensembl chr 5:160,438,697...160,470,171
JBrowse link

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  molecular_function 19910
    catalytic activity 5746
      oxidoreductase activity 814
        oxidoreductase activity, acting on CH-OH group of donors 148
          oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 137
            glucose-6-phosphate dehydrogenase activity 2
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