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ONTOLOGY REPORT - ANNOTATIONS


Term:fumarylacetoacetase activity
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Accession:GO:0004334 term browser browse the term
Definition:Catalysis of the reaction: 4-fumarylacetoacetate + H(2)O = acetoacetate + fumarate + H(+).
Synonyms:related_synonym: 4-fumarylacetoacetate fumarylhydrolase activity;   beta-diketonase activity;   fumarylacetoacetate hydrolase activity
 xref: EC:3.7.1.2;   KEGG_REACTION:R01364;   MetaCyc:FUMARYLACETOACETASE-RXN;   RHEA:10244;   UM-BBD_reactionID:r0107;   reactome:R-HSA-71181 "fumarylacetoacetate => fumarate + acetoacetate"



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fumarylacetoacetase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fah fumarylacetoacetate hydrolase enables TAS
IEA
IBA
ISO
GO_REF:0000116
GO_REF:0000003
PMID:21873635
MGI:2155424|MGI:2155425 (MGI:1929783|PMID:11209059)
RHEA
UniProt
RGD
PMID:11209059 PMID:1916290 PMID:21873635 GO_REF:0000003 GO_REF:0000116 MGI:1929783, RGD:61580, RGD:13792537 NCBI chr 1:138,548,830...138,571,599
Ensembl chr 1:138,548,834...138,571,505
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  molecular_function 19437
    catalytic activity 5609
      hydrolase activity 2343
        hydrolase activity, acting on acid carbon-carbon bonds 3
          hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances 3
            fumarylacetoacetase activity 1
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