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ONTOLOGY REPORT - ANNOTATIONS


Term:ferrochelatase activity
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Accession:GO:0004325 term browser browse the term
Definition:Catalysis of the reaction: heme B (protoheme) + H+ = Fe(2+) + protoporphyrin IX.
Synonyms:related_synonym: ferro-protoporphyrin chelatase activity;   heme synthase activity;   heme synthetase activity;   iron chelatase activity;   protoheme ferro-lyase (protoporphyrin-forming);   protoheme ferro-lyase activity;   protoheme ferrolyase activity
 xref: EC:4.98.1.1;   KEGG_REACTION:R00310;   MetaCyc:PROTOHEMEFERROCHELAT-RXN;   RHEA:22584;   reactome:R-HSA-189465 "FECH binds Fe2+ to PRIN9 to form heme"



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ferrochelatase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FECH ferrochelatase enables ISO
IEA
IBA
RGD
InterPro
UniProt
Ensembl
TreeGrafter
GO_Central
PMID:1316128 GO_REF:0000002 GO_REF:0000033 GO_REF:0000104 GO_REF:0000107 GO_REF:0000118 RGD:1598931 NCBI chr 1:106,861,628...106,898,407
Ensembl chr 1:106,854,011...106,898,591
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  molecular_function 18689
    catalytic activity 5662
      lyase activity 202
        ferrochelatase activity 1
          sirohydrochlorin ferrochelatase activity 0
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