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Term:ferrochelatase activity
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Accession:GO:0004325 term browser browse the term
Definition:Catalysis of the reaction: heme B (protoheme) + H+ = Fe(2+) + protoporphyrin IX.
Synonyms:related_synonym: ferro-protoporphyrin chelatase activity;   heme synthase activity;   heme synthetase activity;   iron chelatase activity;   protoheme ferro-lyase (protoporphyrin-forming);   protoheme ferro-lyase activity;   protoheme ferrolyase activity
 xref: EC:;   KEGG_REACTION:R00310;   MetaCyc:PROTOHEMEFERROCHELAT-RXN;   RHEA:22584;   reactome:R-HSA-189465 "FECH binds Fe2+ to PRIN9 to form heme"

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ferrochelatase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fech ferrochelatase enables IDA
MGI:1858114|MGI:2384729 (MGI:1327758|PMID:9989256), (MGI:2384247|PMID:12149233), (MGI:3041718|PMID:14981080), (MGI:3620268|PMID:16503645), (MGI:3696634|PMID:15496139), (MGI:3794459|PMID:16306232), (MGI:3818407|PMID:17003376), (MGI:60976|PMID:8325637)
(PMID:15123683), (PMID:27599036), (PMID:8973195)
RGD PMID:8325637 PMID:8973195 PMID:9989256 PMID:12149233 PMID:14981080 More... MGI:1327758 MGI:2384247 MGI:3041718 MGI:3620268 MGI:3696634 MGI:3794459 MGI:3818407 MGI:60976, RGD:1598931, RGD:13792537 NCBI chr18:57,945,123...57,978,327
Ensembl chr18:57,945,122...57,979,348
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  molecular_function 19437
    catalytic activity 5609
      lyase activity 204
        ferrochelatase activity 1
          sirohydrochlorin ferrochelatase activity 0
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