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ONTOLOGY REPORT - ANNOTATIONS

Term:serine-type endopeptidase activity
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Accession:GO:0004252 term browser browse the term
Definition:Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a catalytic mechanism that involves a catalytic triad consisting of a serine nucleophile that is activated by a proton relay involving an acidic residue (e.g. aspartate or glutamate) and a basic residue (usually histidine).
Synonyms:related_synonym: blood coagulation factor activity;   serine elastase activity
 xref: EC:3.4.21;   Reactome:R-HSA-114697 "Activated thrombin (factor IIa) cleaves PAR3,4, activating them";   Reactome:R-HSA-1454843 "E-cadherin degradation by MMP3, MMP7 and plasmin";   Reactome:R-HSA-5210912 "Furin cleaves ANTXR2-bound pagA to yield pagA(197-794)";   Reactome:R-HSA-5210935 "Furin cleaves ANTXR1-bound pagA to yield pagA(197-794)";   Reactome:R-HSA-8874145 "MBTPS1 (S1P) cleaves ATF6B (ATF6-beta)";   Reactome:R-HSA-9653249 "Cleavage of factor XII variant by activated thrombin";   Reactome:R-HSA-9655046 "Cleavage of FXII variant by KLKB1";   Reactome:R-HSA-9662786 "FURIN cleaves ADAM17";   Reactome:R-HSA-9666383 "F8 variant is not cleaved by thrombin";   Reactome:R-HSA-9668253 "Hyperactivation of factor X by FVIIIa:FIXa R384L";   Reactome:R-HSA-9668365 "FVIIIa variant:FIXa does not convert FX to the active FXa";   Reactome:R-HSA-9670874 "FIXa variant:FVIIIa does not convert FX to the active FXa";   Reactome:R-HSA-9673223 "FIX(29-461) variant is not activated (factor XIa catalyst)";   Reactome:R-HSA-9686710 "Cleavage of S protein into S1:S2";   Reactome:R-HSA-9686731 "TMPRSS2 Mediated SARS-CoV-1 Spike Protein Cleavage and Endocytosis";   Reactome:R-HSA-9694287 "Cleavage of S protein into S1:S2";   Reactome:R-HSA-9694661 "TMPRSS2 Mediated SARS-CoV-2 Spike Protein Cleavage and Endocytosis";   Reactome:R-HSA-9698988 "Direct Host Cell Membrane Membrane Fusion and Release of SARS-CoV-2 Nucleocapsid";   Reactome:R-HSA-9699007 "FURIN Mediated SARS-CoV-2 Spike Protein Cleavage and Endocytosis";   Reactome:R-HSA-9708859 "Activated thrombin (factor IIa) cleaves F2R (PAR1), activating it";   Reactome:R-HSA-9710106 "ELANE cleaves GSDMD";   Reactome:R-HSA-9710263 "GZMB cleaves GSDME";   Reactome:R-HSA-9769949 "FURIN Mediated SARS-CoV-2 Spike Protein Cleavage";   Reactome:R-HSA-9770187 "S2 Cleavage by TMPRSS2 Exposes S2' Initiating Cell-Cell Fusion";   Reactome:R-HSA-9829030 "Nascent F signal peptide is cleaved at ER membrane";   Reactome:R-HSA-9829200 "F0 is cleaved, releasing F1, F2, F(110-136)";   Reactome:R-HSA-9830805 "Nascent sG localizes to ER lumen, gets glycosylated";   Reactome:R-HSA-9830882 "Nascent G signal peptide is cleaved at ER membrane";   Reactome:R-HSA-9839367 "TGFBR3_mem cleavage by MMPs";   reactome:R-HSA-1181152 "Cleavage of NODAL proprotein";   reactome:R-HSA-139893 "Granzyme-B activates BID by cleavage";   reactome:R-HSA-140599 "factor XIII -> factor XIII cleaved tetramer + 2 factor XIII A activation peptides";   reactome:R-HSA-140664 "prothrombin -> activated thrombin (factor IIa) + thrombin activation peptide (prothrombinase catalyst)";   reactome:R-HSA-140696 "factor V -> factor Va + factor V activation peptide";   reactome:R-HSA-140700 "prothrombin -> activated thrombin (factor IIa) + thrombin activation peptide (Xa catalyst)";   reactome:R-HSA-140736 "factor X -> factor Xa + factor X activation peptide (TF:F7a catalyst)";   reactome:R-HSA-140769 "factor VII -> factor VIIa";   reactome:R-HSA-140777 "factor X -> factor Xa + factor X activation peptide (TF:F7 catalyst)";   reactome:R-HSA-140823 "factor IX -> factor IXa + factor IX activation peptide (TF:F7a catalyst)";   reactome:R-HSA-140840 "fibrinogen -> fibrin monomer + 2 fibrinopeptide A + 2 fibrinopeptide B";   reactome:R-HSA-140870 "thrombin:antithrombin III:heparin -> thrombin:cleaved antithrombin III:heparin";   reactome:R-HSA-141026 "Activated protein C cleaves factor Va to factor Vi intermediate form";   reactome:R-HSA-141040 "Activated thrombin:thrombomodulin cleaves PROCR:Protein C to PROCR:Activated protein C";   reactome:R-HSA-1474197 "Collagen type II degradation by MMP1,3,8,13,PRSS2";   reactome:R-HSA-1566962 "Elastin degradation by elastin-degrading extracellular proteinases";   reactome:R-HSA-1566979 "Laminin-332 degradation by laminin-322 degrading extracellular proteinases";   reactome:R-HSA-1566981 "Fibronectin degradation by MMP1, 3, 7, 12, 13, 19, CTSS";   reactome:R-HSA-158137 "factor VIII:von Willibrand factor multimer -> factor VIIIa + factor VIIIa B A3 acidic polypeptide + von Willibrand factor multimer";   reactome:R-HSA-158164 "factor X -> factor Xa + factor X activation peptide (VIIIa:IXa catalyst)";   reactome:R-HSA-158300 "factor XI:platelet glycoprotein (GP) Ib:IX:V complex -> factor XIa:platelet glycoprotein (GP) Ib:IX:V complex (XIIa catalyst)";   reactome:R-HSA-158311 "kallikrein:kininogen:C1q binding protein tetramer -> kallikrein + activated kininogen:C1q binding protein tetramer + bradykinin";   reactome:R-HSA-158313 "factor XII -> factor XIIa";   reactome:R-HSA-158333 "factor IX -> factor IXa + factor IX activation peptide (factor XIa catalyst)";   reactome:R-HSA-158419 "factor XI:platelet glycoprotein (GP) Ib:IX:V complex -> factor XIa:platelet glycoprotein (GP) Ib:IX:V complex (thrombin catalyst)";   reactome:R-HSA-158744 "crosslinked fibrin multimer:tissue plasminogen activator (two-chain):plasminogen -> crosslinked fibrin multimer:tissue plasminogen activator (two-chain) + plasmin";   reactome:R-HSA-158747 "crosslinked fibrin multimer:tissue plasminogen activator (one-chain) -> crosslinked fibrin multimer:tissue plasminogen activator (two-chain)";   reactome:R-HSA-158750 "crosslinked fibrin multimer:tissue plasminogen activator (one-chain):plasminogen -> crosslinked fibrin multimer:tissue plasminogen activator (one-chain) + plasmin";   reactome:R-HSA-158766 "fibrin multimer, crosslinked -> fibrin digestion products (plasmin)";   reactome:R-HSA-158925 "plasminogen:histidine-rich glycoprotein -> plasmin + histidine-rich glycoprotein (uPA [two-chain] catalyst)";   reactome:R-HSA-158942 "urokinase plasminogen activator (one-chain):uPAR -> urokinase plasminogen activator (two-chain):uPAR";   reactome:R-HSA-158982 "plasminogen:histidine-rich glycoprotein -> plasmin + histidine-rich glycoprotein (uPA [one-chain] catalyst)";   reactome:R-HSA-1592270 "NID1 degradation by MMP1, 9, 12, ELANE";   reactome:R-HSA-1592278 "Autocatalytic activation of proMMP2";   reactome:R-HSA-1592297 "Full activation of MMP1";   reactome:R-HSA-1592314 "HSPG2 (perlecan) degradation by MMP3, plasmin, (MMP12)";   reactome:R-HSA-1592316 "Initial activation of proMMP1";   reactome:R-HSA-1592362 "Activation of proMMP7 by MMP3";   reactome:R-HSA-1592371 "Initial activation of proMMP3";   reactome:R-HSA-1592398 "Activation of proMMP8";   reactome:R-HSA-1592436 "Initial activation of proMMP9 by MMPs";   reactome:R-HSA-159728 "Furin cleaves pro-prothrombin to prothrombin";   reactome:R-HSA-159733 "Furin cleaves pro-factor X to factor X";   reactome:R-HSA-159771 "Furin cleaves pro-protein C to protein C";   reactome:R-HSA-159773 "Furin cleaves pro-protein S to protein S";   reactome:R-HSA-159796 "Furin cleaves pro-factor IX to factor IX";   reactome:R-HSA-159868 "Furin cleaves pro-factor VII to factor VII";   reactome:R-HSA-1602458 "Activation of proMMP10";   reactome:R-HSA-1602466 "Activation of MT-MMPs by FURIN";   reactome:R-HSA-1602473 "Autocatalytic activation of MMP1";   reactome:R-HSA-1602484 "Activation of proMMP11 by FURIN";   reactome:R-HSA-1602488 "Initial activation of proMMP13 by plasmin and trypsin";   reactome:R-HSA-1604359 "Initial activation of proMMP2 by MMP1, 7";   reactome:R-HSA-1604360 "Initial activation of proMMP2 by MMP14";   reactome:R-HSA-1604368 "Autocatalytic activation of bound proMMP2";   reactome:R-HSA-1604690 "Activation of MMP9 intermediate form by MMPs";   reactome:R-HSA-1604712 "Initial activation of proMMP7 by trypsin";   reactome:R-HSA-1604722 "Activation of proMMP9 by proteases";   reactome:R-HSA-1604731 "Autocatalytic activation of MMP3";   reactome:R-HSA-1604732 "Autocatalytic activation of proMMP13";   reactome:R-HSA-1604741 "Initial activation of proMMP13 by MMP14 (MT1-MMP)";   reactome:R-HSA-1604752 "Initial activation of proMMP13 by MMP3";   reactome:R-HSA-1604763 "Autocatalytic activation of MMP7";   reactome:R-HSA-163798 "Furin cleaves pro-protein Z to protein Z";   reactome:R-HSA-163843 "Furin cleaves pro-GAS6 to GAS6";   reactome:R-HSA-1655842 "S1P hydrolyzes SREBP1A,1C,2";   reactome:R-HSA-166753 "Conversion of C4 into C4a and C4b";   reactome:R-HSA-166792 "Conversion of C2 into C2a and C2b";   reactome:R-HSA-166817 "Cleavage of C3 by C3 convertases";   reactome:R-HSA-170844 "Latent TGF-beta-1 is cleaved by furin";   reactome:R-HSA-171288 "Cleavage of the viral Env gp160 precursor polyprotein";   reactome:R-HSA-173626 "Activation of C1r";   reactome:R-HSA-173631 "Activation of C1s";   reactome:R-HSA-173680 "Activation of C5";   reactome:R-HSA-173745 "Factor D cleaves C3(H2O)-bound Factor B";   reactome:R-HSA-174551 "Formation of alternative pathway C5 convertase";   reactome:R-HSA-1799329 "Signal peptidase hydrolyzes signal peptide from ribosome-associated nascent protein";   reactome:R-HSA-183122 "Factor D cleaves C3b-bound Factor B";   reactome:R-HSA-183130 "C3(H2O):Factor Bb cleaves C3 to C3b and C3a";   reactome:R-HSA-186785 "PDGF-AA clevage by Furin";   reactome:R-HSA-187020 "Part of pro-beta-NGF is processed to mature beta-NGF";   reactome:R-HSA-1912369 "NOTCH precursor cleaved to form mature NOTCH";   reactome:R-HSA-1912372 "Fringe-modified Pre-NOTCH is cleaved by FURIN";   reactome:R-HSA-2022411 "Cathepsin G hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8)";   reactome:R-HSA-2129357 "Fibrillin C-terminal processing";   reactome:R-HSA-2168923 "Collagen type XVIII endostatin release";   reactome:R-HSA-2168960 "Collagen type XVII ectodomain shedding";   reactome:R-HSA-2172405 "Collagen type XXIII ectodomain shedding";   reactome:R-HSA-2214330 "Cleavage of collagen VII NC2 region by BMP1";   reactome:R-HSA-2471621 "Endostatin degradation by cathepsins";   reactome:R-HSA-2471842 "Collagen type XXV ectomain shedding";   reactome:R-HSA-2482180 "Collagen type VIII degradation by ELANE";   reactome:R-HSA-2514772 "Fibrillin-1 degradation by MMP3, CTSK, CTSL2";   reactome:R-HSA-2514823 "Fibrillin-1 degradation by ELANE";   reactome:R-HSA-2534160 "HSPG2 (perlecan) degradation by MMP13, CTSS";   reactome:R-HSA-2534206 "E-cadherin degradation by PS1:NCSTN (Gamma-secretase)";   reactome:R-HSA-2534260 "E-cadherin degradation by caspase-3 and calpain-1";   reactome:R-HSA-265301 "Corticotropin cleavage from POMC";   reactome:R-HSA-3266557 "Factor I cleaves iC3b";   reactome:R-HSA-3785684 "Fibronectin degradation by CTSG";   reactome:R-HSA-3788061 "Fibronectin degradation by ADAM8";   reactome:R-HSA-381135 "MBTPS1 (S1P) cleaves ATF6 (ATF6-alpha)";   reactome:R-HSA-381446 "Thrombin proteolyzes IGF:IGFBP3:ALS";   reactome:R-HSA-381461 "Plasmin proteolyzes IGF:IGFBP-3:ALS";   reactome:R-HSA-381466 "Prostate-specific Antigen proteolyzes IGF:IGFBP3:ALS";   reactome:R-HSA-3814820 "HSPG2 (perlecan) is cleaved by BMP1, TLL1, TLL2, Cathepsin L1";   reactome:R-HSA-381500 "Cathepsin G proteolyzes IGF:IGFBP3:ALS";   reactome:R-HSA-381798 "PCSK1 hydrolyzes Proglucagon to Glucagon-like Peptide-1";   reactome:R-HSA-382061 "Extracellular processing of novel PDGFs";   reactome:R-HSA-3928657 "MMP2,9 cleave EPHB";   reactome:R-HSA-400459 "Signal peptidase hydrolyzes preproGLP-1 to proGLP-1";   reactome:R-HSA-400492 "PCSK1 hydrolyzes proGIP to GIP";   reactome:R-HSA-400496 "Signal peptidase hydrolyzes preproGIP to proGIP";   reactome:R-HSA-422021 "PCSK1 hydrolyzes acyl Proghrelin to acyl Ghrelin";   reactome:R-HSA-422051 "Cleavage of the signal peptide of Preproghrelin";   reactome:R-HSA-5578783 "CORIN(802-1042) hydrolyses NPPA to form NPPA(124-151)";   reactome:R-HSA-5591040 "Activated protein C cleaves Factor Va intermediate form for Factor Va";   reactome:R-HSA-5607002 "Activated protein C cleaves factor VIIIa";   reactome:R-HSA-5691512 "APEH hydrolyses NAc-Ser-protein";   reactome:R-HSA-6800198 "HPN heterodimer cleaves pro-MST1 to form MST1 dimer";   reactome:R-HSA-6800200 "HPN heterodimer cleaves pro-HGF to form HGF dimer";   reactome:R-HSA-6800299 "HGFAC cleaves pro-HGF to form HGF dimer";   reactome:R-HSA-6801687 "PRTN3 cleaves CAMP(31-170) to generate CAMP(134-170)";   reactome:R-HSA-6807224 "Furin cleaves pro-BGLAP to BGLAP";   reactome:R-HSA-8849826 "ST14 hydrolyzes and activates KLK5";   reactome:R-HSA-8849857 "KLK5 cleaves and activates CELA2";   reactome:R-HSA-8850831 "KLK5 cleaves and activates KLK8";   reactome:R-HSA-8852716 "Thrombin, ELANE cleave C5";   reactome:R-HSA-8855825 "HTRA1 hydrolyzes ACAN (Aggrecan)";   reactome:R-HSA-8865275 "PDGF-BB clevage by Furin";   reactome:R-HSA-8865276 "PDGF-AB clevage by Furin";   reactome:R-HSA-8874186 "MBTPS1 (S1P) cleaves CREB3L4";   reactome:R-HSA-8874204 "MBTPS1 (S1P) cleaves CREB3";   reactome:R-HSA-8874205 "MBTPS1 (S1P) cleaves CREB3L2";   reactome:R-HSA-8874206 "MBTPS1 (S1P) cleaves CREB3L3";   reactome:R-HSA-8874212 "MBTPS1 (S1P) cleaves CREB3L1";   reactome:R-HSA-9023178 "PCSK2 cleaves Insulin(57-110) to yield Insulin(90-110) and C-peptide (Insulin(57-89))";   reactome:R-HSA-9023196 "PCSK1 cleaves proinsulin to yield Insulin(25-56) and Insulin(57-110)";   reactome:R-HSA-9023626 "DPP4(39-766) hydrolyzes Glucose-dependent Insulinotropic Polypeptide (GIP)";   reactome:R-HSA-9023627 "DPP4(1-766) hydrolyzes Glucose-dependent Insulinotropic Polypeptide (GIP)";   reactome:R-HSA-9023632 "DPP4(39-766) hydrolyzes Glucagon-like Peptide-1 (GLP-1)";   reactome:R-HSA-9023633 "DPP4(1-766) hydrolyzes Glucagon-like Peptide-1 (GLP-1)";   reactome:R-HSA-9033490 "TYSND1 cleaves PHYH";   reactome:R-HSA-9033506 "TYSND1 cleaves AGPS";   reactome:R-HSA-9033515 "TYSND1 cleaves ACOX1";   reactome:R-HSA-9033520 "TYSND1 cleaves TYSND1";   reactome:R-HSA-9033524 "TYSND1 cleaves SCP2";   reactome:R-HSA-9033529 "TYSND1 cleaves ACAA1";   reactome:R-HSA-9033530 "TYSND1 cleaves HSD17B4";   reactome:R-HSA-976743 "Factor I inactivates plasma Factor H-bound C3b";   reactome:R-HSA-977371 "Factor I inactivates Factor H-boundC3b";   reactome:R-HSA-977615 "Factor I inactivates MCP/CR1-bound C4b/C3b"


show annotations for term's descendants           Sort by:
serine-type endopeptidase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G 1810009J06Rikl RIKEN cDNA 1810009J06 gene like enables IEA
IBA 		GO_REF:0000002
GO_REF:0000033
GO_REF:0000003 		InterPro
GO_Central
UniProt		 GO_REF:0000002 GO_REF:0000003 GO_REF:0000033 NCBI chr 4:69,815,107...69,826,206
Ensembl chr 4:69,815,108...69,818,851 		JBrowse link
G 4930519F16Rikl RIKEN cDNA 4930519F16 gene like enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr  X:68,187,517...68,220,029
Ensembl chr  X:68,187,704...68,219,986 		JBrowse link
G AABR07018028.1 enables IBA
IEA 		GO_REF:0000033
GO_REF:0000002 		GO_Central
InterPro		 GO_REF:0000002 GO_REF:0000033 Ensembl chr15:30,289,611...30,291,562 JBrowse link
G Acr acrosin enables TAS
ISS
ISO
IBA
IEA 		PMID:12398221
GO_REF:0000024
(PMID:6802470)
GO_REF:0000033
GO_REF:0000003
GO_REF:0000107
GO_REF:0000002 		UniProt
RGD
GO_Central
Ensembl
InterPro		 PMID:6802470 PMID:12398221 GO_REF:0000002 GO_REF:0000003 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107, RGD:8553887 NCBI chr 7:120,636,581...120,644,474
Ensembl chr 7:120,638,321...120,644,474 		JBrowse link
G Apeh acylaminoacyl-peptide hydrolase enables ISO
IEA
IBA 		(PMID:17241160)
GO_REF:0000107
GO_REF:0000002
GO_REF:0000033 		RGD
Ensembl
InterPro
GO_Central		 PMID:17241160 GO_REF:0000002 GO_REF:0000033 GO_REF:0000107 NCBI chr 8:108,773,791...108,782,903
Ensembl chr 8:108,773,794...108,782,933 		JBrowse link
G Bin2 bridging integrator 2 enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 7:131,742,001...131,768,208
Ensembl chr 7:131,742,002...131,786,285 		JBrowse link
G C1r complement C1r enables ISO
IBA
IEA 		(PMID:11823416)
GO_REF:0000033
GO_REF:0000003
GO_REF:0000002 		RGD
GO_Central
UniProt
InterPro		 PMID:11823416 GO_REF:0000002 GO_REF:0000003 GO_REF:0000033 NCBI chr 4:157,412,718...157,423,483
Ensembl chr 4:157,412,692...157,423,484 		JBrowse link
G C1rl complement C1r subcomponent like enables IEA
IBA 		GO_REF:0000002
GO_REF:0000033 		InterPro
GO_Central		 GO_REF:0000002 GO_REF:0000033 NCBI chr 4:157,394,183...157,410,771
Ensembl chr 4:157,394,200...157,410,134 		JBrowse link
G C1s complement C1s enables ISO
IEA
IBA 		(PMID:11527969)
GO_REF:0000107
GO_REF:0000002
GO_REF:0000033
GO_REF:0000003 		RGD
Ensembl
InterPro
GO_Central
UniProt		 PMID:11527969 GO_REF:0000002 GO_REF:0000003 GO_REF:0000033 GO_REF:0000107 NCBI chr 4:157,430,249...157,442,438
Ensembl chr 4:157,430,117...157,442,303 		JBrowse link
G C2 complement C2 enables IEA GO_REF:0000003
GO_REF:0000002 		UniProt
InterPro		 GO_REF:0000002 GO_REF:0000003 NCBI chr20:3,951,474...3,970,376
Ensembl chr20:3,951,474...3,976,505 		JBrowse link
G Cela1 chymotrypsin like elastase 1 enables IEA
ISS
IBA
ISO 		GO_REF:0000002
GO_REF:0000024
GO_REF:0000033
(PMID:35749514)
GO_REF:0000003
GO_REF:0000107 		InterPro
UniProt
GO_Central
RGD
Ensembl		 PMID:35749514 GO_REF:0000002 GO_REF:0000003 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr 7:131,773,161...131,786,300
Ensembl chr 7:131,742,002...131,786,285 		JBrowse link
G Cela2a chymotrypsin like elastase 2A enables IBA
IEA 		GO_REF:0000033
GO_REF:0000003
GO_REF:0000002 		GO_Central
UniProt
InterPro		 GO_REF:0000002 GO_REF:0000003 GO_REF:0000033 NCBI chr 5:154,126,879...154,136,630
Ensembl chr 5:154,126,878...154,136,632 		JBrowse link
G Cela3b chymotrypsin like elastase 3B enables IBA
IEA 		GO_REF:0000033
GO_REF:0000002 		GO_Central
InterPro		 GO_REF:0000002 GO_REF:0000033 NCBI chr 5:149,628,773...149,636,937
Ensembl chr 5:149,628,773...149,636,937 		JBrowse link
G Cfb complement factor B enables IEA GO_REF:0000003
GO_REF:0000002 		UniProt
InterPro		 GO_REF:0000002 GO_REF:0000003 NCBI chr20:3,970,643...3,976,510
Ensembl chr20:3,951,474...3,976,505 		JBrowse link
G Cfd complement factor D enables TAS
IEA
IBA 		GO_REF:0000003
GO_REF:0000033
GO_REF:0000002 		UniProt
GO_Central
InterPro
RGD		 PMID:12949072 GO_REF:0000002 GO_REF:0000003 GO_REF:0000033, RGD:1298875 NCBI chr 7:9,813,148...9,814,871
Ensembl chr 7:9,813,150...9,815,053 		JBrowse link
G Cfi complement factor I enables IEA GO_REF:0000003
GO_REF:0000002 		UniProt
InterPro		 GO_REF:0000002 GO_REF:0000003 NCBI chr 2:218,389,079...218,430,565
Ensembl chr 2:218,387,990...218,430,561 		JBrowse link
G Clpp caseinolytic mitochondrial matrix peptidase proteolytic subunit enables ISO
IBA
IEA 		(PMID:11923310)
GO_REF:0000033
GO_REF:0000002
GO_REF:0000107
GO_REF:0000003 		RGD
GO_Central
InterPro
Ensembl
UniProt		 PMID:11923310 GO_REF:0000002 GO_REF:0000003 GO_REF:0000033 GO_REF:0000107 NCBI chr 9:1,831,680...1,837,700
Ensembl chr 9:1,830,311...1,837,693 		JBrowse link
G Cma1 chymase 1 enables IDA
IMP
ISO
IBA
IEA 		(PMID:1919436)
GO_REF:0000033
GO_REF:0000003
GO_REF:0000002
GO_REF:0000107 		RGD
GO_Central
UniProt
InterPro
Ensembl		 PMID:1919436 PMID:12444981 PMID:15869764 GO_REF:0000002 GO_REF:0000003 GO_REF:0000033 GO_REF:0000107, RGD:5115549, RGD:1581745 NCBI chr15:29,417,451...29,420,233
Ensembl chr15:29,417,451...29,420,233 		JBrowse link
G Corin corin, serine peptidase enables IEA
ISO 		GO_REF:0000107
(PMID:10880574), (PMID:21763278)
(PMID:21518754)
GO_REF:0000002
(PMID:11884416) 		Ensembl
RGD
InterPro		 PMID:10880574 PMID:11884416 PMID:21518754 PMID:21763278 GO_REF:0000002 GO_REF:0000107 NCBI chr14:35,680,601...35,910,703
Ensembl chr14:35,681,304...35,909,503 		JBrowse link
G Csmd1 CUB and Sushi multiple domains 1 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr16:72,218,189...73,818,380
Ensembl chr16:72,218,503...73,817,614 		JBrowse link
G Csmd3 CUB and Sushi multiple domains 3 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 7:78,747,322...80,066,466
Ensembl chr 7:78,748,480...80,066,369 		JBrowse link
G Ctrb1 chymotrypsinogen B1 enables IDA
IEA
IBA
ISO 		GO_REF:0000002
GO_REF:0000033
(PMID:23814066)
GO_REF:0000003 		InterPro
GO_Central
RGD
UniProt		 PMID:23814066 PMID:8635580 GO_REF:0000002 GO_REF:0000003 GO_REF:0000033, RGD:2303361 NCBI chr19:39,652,931...39,657,689
Ensembl chr19:39,652,933...39,657,688 		JBrowse link
G Ctrc chymotrypsin C enables IEA
IBA
ISO 		GO_REF:0000002
GO_REF:0000033
(PMID:23814066) 		InterPro
GO_Central
RGD		 PMID:23814066 GO_REF:0000002 GO_REF:0000033 NCBI chr 5:154,147,314...154,156,540
Ensembl chr 5:154,147,316...154,156,528 		JBrowse link
G Ctrl chymotrypsin-like enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr19:33,827,279...33,829,129
Ensembl chr19:33,827,229...33,833,626 		JBrowse link
G Ctsc cathepsin C enables ISO
IEA 		(PMID:20435891)
GO_REF:0000107 		RGD
Ensembl		 PMID:20435891 GO_REF:0000107 NCBI chr 1:142,028,386...142,059,841
Ensembl chr 1:142,028,392...142,060,387 		JBrowse link
G Ctsg cathepsin G enables ISO
ISS
IEA
IBA 		(PMID:10512690), (PMID:12504904), (PMID:15100291), (PMID:8194606)
GO_REF:0000024
GO_REF:0000107
GO_REF:0000033
GO_REF:0000003
GO_REF:0000002 		RGD
UniProt
Ensembl
GO_Central
InterPro		 PMID:8194606 PMID:10512690 PMID:12504904 PMID:15100291 GO_REF:0000002 GO_REF:0000003 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr15:29,930,988...29,937,353
Ensembl chr15:29,931,003...29,937,353 		JBrowse link
G Ctsh cathepsin H enables ISS
ISO
IEA 		GO_REF:0000024
(PMID:20435891)
GO_REF:0000107 		UniProt
RGD
Ensembl		 PMID:20435891 GO_REF:0000024 GO_REF:0000107 NCBI chr 8:90,608,941...90,627,824
Ensembl chr 8:90,608,941...90,627,824 		JBrowse link
G Ctss cathepsin S enables TAS Reactome:R-NUL-2534170 Reactome Reactome:R-NUL-2534170 NCBI chr 2:183,086,437...183,114,483
Ensembl chr 2:183,086,437...183,114,483 		JBrowse link
G Dag1 dystroglycan 1 enables ISO (PMID:17905726) RGD PMID:17905726 NCBI chr 8:108,890,926...108,955,611
Ensembl chr 8:108,890,929...108,952,325 		JBrowse link
G Dpp4 dipeptidylpeptidase 4 enables IEA
ISO 		GO_REF:0000002
(PMID:8100523), (PMID:8798518) 		InterPro
RGD		 PMID:8100523 PMID:8798518 GO_REF:0000002 NCBI chr 3:46,962,233...47,043,870
Ensembl chr 3:46,962,243...47,043,901 		JBrowse link
G Elane elastase, neutrophil expressed enables ISO
IBA
IEA 		(PMID:29539421), (PMID:36899106)
GO_REF:0000033
(PMID:17878334)
GO_REF:0000107
GO_REF:0000002 		RGD
GO_Central
Ensembl
InterPro		 PMID:17878334 PMID:29539421 PMID:36899106 GO_REF:0000002 GO_REF:0000033 GO_REF:0000107 NCBI chr 7:9,817,251...9,819,174
Ensembl chr 7:9,817,252...9,819,100 		JBrowse link
G ENSRNOG00000063491 enables IEA GO_REF:0000104
GO_REF:0000002 		UniProt
InterPro		 GO_REF:0000002 GO_REF:0000104 Ensembl chr16:35,225,583...35,226,806 JBrowse link
G ENSRNOG00000065143 enables IEA GO_REF:0000002 InterPro GO_REF:0000002 Ensembl chr 1:94,542,790...94,544,544 JBrowse link
G ENSRNOG00000066085 enables IEA GO_REF:0000002 InterPro GO_REF:0000002 Ensembl chr 1:183,970,898...183,971,787 JBrowse link
G ENSRNOG00000066632 enables IEA GO_REF:0000002 InterPro GO_REF:0000002 Ensembl chr 1:109,429,008...109,430,103 JBrowse link
G ENSRNOG00000066972 enables IBA
IEA 		GO_REF:0000033
GO_REF:0000002 		GO_Central
InterPro		 GO_REF:0000002 GO_REF:0000033 Ensembl chr 1:94,518,965...94,532,051 JBrowse link
G ENSRNOG00000067174 enables IBA
IEA 		GO_REF:0000033
GO_REF:0000002 		GO_Central
InterPro		 GO_REF:0000002 GO_REF:0000033 Ensembl chr 1:94,557,968...94,568,968 JBrowse link
G ENSRNOG00000067591 enables IBA
IEA 		GO_REF:0000033
GO_REF:0000002 		GO_Central
InterPro		 GO_REF:0000002 GO_REF:0000033 Ensembl chr 4:70,320,043...70,320,752 JBrowse link
G ENSRNOG00000068507 enables IBA
IEA 		GO_REF:0000033
GO_REF:0000002 		GO_Central
InterPro		 GO_REF:0000002 GO_REF:0000033 Ensembl chr 1:94,635,889...94,640,675 JBrowse link
G ENSRNOG00000068886 enables IEA GO_REF:0000002 InterPro GO_REF:0000002 Ensembl chr 1:94,651,856...94,654,712 JBrowse link
G ENSRNOG00000069479 enables IBA
IEA 		GO_REF:0000033
GO_REF:0000002 		GO_Central
InterPro		 GO_REF:0000002 GO_REF:0000033 Ensembl chr 1:94,459,406...94,464,664 JBrowse link
G ENSRNOG00000071144 enables IBA
IEA 		GO_REF:0000033
GO_REF:0000002 		GO_Central
InterPro		 GO_REF:0000002 GO_REF:0000033 Ensembl chr 1:94,395,534...94,397,417 JBrowse link
G F10 coagulation factor X enables ISO
IEA
IBA 		(PMID:12574802), (PMID:17469850)
GO_REF:0000117
GO_REF:0000033
GO_REF:0000002
GO_REF:0000003
GO_REF:0000107 		RGD
UniProt
GO_Central
InterPro
Ensembl		 PMID:12574802 PMID:17469850 GO_REF:0000002 GO_REF:0000003 GO_REF:0000033 GO_REF:0000107 GO_REF:0000117 NCBI chr16:76,468,834...76,488,141
Ensembl chr16:76,468,838...76,488,141 		JBrowse link
G F11 coagulation factor XI enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr16:46,987,988...47,009,015
Ensembl chr16:46,986,107...47,008,437 		JBrowse link
G F12 coagulation factor XII enables IEA
ISO
IBA 		GO_REF:0000107
(PMID:18725990), (PMID:6793628)
GO_REF:0000002
GO_REF:0000033
GO_REF:0000003 		Ensembl
RGD
InterPro
GO_Central
UniProt		 PMID:6793628 PMID:18725990 GO_REF:0000002 GO_REF:0000003 GO_REF:0000033 GO_REF:0000107 NCBI chr17:9,207,683...9,215,530
Ensembl chr17:9,207,683...9,215,530 		JBrowse link
G F2 coagulation factor II, thrombin enables ISO
IEA
IBA 		(PMID:12855810), (PMID:1672265)
GO_REF:0000003
GO_REF:0000002
GO_REF:0000033
(PMID:18398001)
GO_REF:0000107 		RGD
UniProt
InterPro
GO_Central
Ensembl		 PMID:1672265 PMID:12855810 PMID:18398001 GO_REF:0000002 GO_REF:0000003 GO_REF:0000033 GO_REF:0000107 NCBI chr 3:77,596,196...77,609,486
Ensembl chr 3:77,596,198...77,609,486 		JBrowse link
G F3 coagulation factor III, tissue factor contributes_to ISO
IEA 		(PMID:24998411)
GO_REF:0000107 		RGD
Ensembl		 PMID:24998411 GO_REF:0000107 NCBI chr 2:209,827,061...209,838,666
Ensembl chr 2:209,826,959...209,838,668 		JBrowse link
G F7 coagulation factor VII contributes_to
enables 		ISO
IEA
IBA 		(PMID:24998411)
GO_REF:0000002
GO_REF:0000033
GO_REF:0000107
GO_REF:0000003 		RGD
InterPro
GO_Central
Ensembl
UniProt		 PMID:24998411 GO_REF:0000002 GO_REF:0000003 GO_REF:0000033 GO_REF:0000107 NCBI chr16:76,489,775...76,500,636
Ensembl chr16:76,489,717...76,500,610 		JBrowse link
G F9 coagulation factor IX enables IEA
IBA 		GO_REF:0000002
GO_REF:0000033
GO_REF:0000003 		InterPro
GO_Central
UniProt		 GO_REF:0000002 GO_REF:0000003 GO_REF:0000033 NCBI chr  X:138,352,334...138,396,835
Ensembl chr  X:138,352,298...138,396,835 		JBrowse link
G Fap fibroblast activation protein, alpha enables ISO
IEA 		(PMID:10593948)
GO_REF:0000002
GO_REF:0000107 		RGD
InterPro
Ensembl		 PMID:10593948 GO_REF:0000002 GO_REF:0000107 NCBI chr 3:47,138,823...47,207,671
Ensembl chr 3:47,138,813...47,225,545 		JBrowse link
G Furin furin (paired basic amino acid cleaving enzyme) enables IMP
ISS
ISO
IEA
IBA 		GO_REF:0000024
(PMID:10567353), (PMID:11799113), (PMID:1438214), (PMID:1644824), (PMID:21763278), (PMID:7737999), (PMID:8615794), (PMID:9130696)
GO_REF:0000104
GO_REF:0000033
(PMID:12447384), (PMID:26416966)
GO_REF:0000002
GO_REF:0000107
GO_REF:0000003 		UniProt
RGD
GO_Central
InterPro
Ensembl		 PMID:1438214 PMID:1644824 PMID:7737999 PMID:8615794 PMID:9130696 More... GO_REF:0000002 GO_REF:0000003 GO_REF:0000024 GO_REF:0000033 GO_REF:0000104 GO_REF:0000107, RGD:1582619 NCBI chr 1:134,348,142...134,361,182
Ensembl chr 1:134,348,144...134,364,314 		JBrowse link
G Gzma granzyme A enables ISO
IBA
IEA 		(PMID:11331782), (PMID:12819770), (PMID:32299851), (PMID:34022140), (PMID:36899106)
GO_REF:0000033
GO_REF:0000107
GO_REF:0000002 		RGD
GO_Central
Ensembl
InterPro		 PMID:11331782 PMID:12819770 PMID:32299851 PMID:34022140 PMID:36899106 GO_REF:0000002 GO_REF:0000033 GO_REF:0000107 NCBI chr 2:44,740,569...44,752,502
Ensembl chr 2:44,740,569...44,752,493 		JBrowse link
G Gzmb granzyme B enables IDA
ISO
IEA
IBA 		(PMID:11331782), (PMID:20038786), (PMID:31953257), (PMID:32188940), (PMID:9852092)
GO_REF:0000002
(PMID:35705808)
GO_REF:0000033
GO_REF:0000003 		RGD
InterPro
GO_Central
UniProt		 PMID:9852092 PMID:11331782 PMID:20038786 PMID:31953257 PMID:32188940 More... GO_REF:0000002 GO_REF:0000003 GO_REF:0000033, RGD:2325279 NCBI chr15:30,343,352...30,346,814
Ensembl chr15:30,173,603...30,346,814 		JBrowse link
G Gzmbl1 Granzyme B-like 1 enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr15:30,086,674...30,090,455
Ensembl chr15:30,087,130...30,090,037 		JBrowse link
G Gzmbl3 Granzyme B-like 3 enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr15:30,173,712...30,176,441
Ensembl chr15:30,087,127...30,206,702 		JBrowse link
G Gzmc granzyme C enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr15:30,321,653...30,324,347
Ensembl chr15:30,173,603...30,346,814
Ensembl chr15:30,173,603...30,346,814
Ensembl chr15:30,173,603...30,346,814 		JBrowse link
G Gzmc-ps2 granzyme C, pseudogene 2 enables IBA
IEA 		GO_REF:0000033
GO_REF:0000002 		GO_Central
InterPro		 GO_REF:0000002 GO_REF:0000033 NCBI chr15:30,240,621...30,251,275
Ensembl chr15:30,240,621...30,251,349
Ensembl chr15:30,240,621...30,251,349 		JBrowse link
G Gzmf granzyme F enables IBA
IEA 		GO_REF:0000033
GO_REF:0000002 		GO_Central
InterPro		 GO_REF:0000002 GO_REF:0000033 NCBI chr15:30,005,361...30,018,649
Ensembl chr15:30,007,267...30,018,649 		JBrowse link
G Gzmfl1 Granzyme F like 1 enables IBA
IEA 		GO_REF:0000033
GO_REF:0000002 		GO_Central
InterPro		 GO_REF:0000002 GO_REF:0000033 NCBI chr15:29,986,103...29,988,926
Ensembl chr15:29,986,103...29,988,926 		JBrowse link
G Gzmk granzyme K enables ISO
IEA
IBA 		(PMID:10480954)
GO_REF:0000107
GO_REF:0000002
GO_REF:0000033 		RGD
Ensembl
InterPro
GO_Central		 PMID:10480954 GO_REF:0000002 GO_REF:0000033 GO_REF:0000107 NCBI chr 2:44,840,811...44,848,829
Ensembl chr 2:44,840,811...44,848,894 		JBrowse link
G Gzmm granzyme M enables ISO
IEA
IBA 		(PMID:21857942)
GO_REF:0000107
GO_REF:0000002
GO_REF:0000033 		RGD
Ensembl
InterPro
GO_Central		 PMID:21857942 GO_REF:0000002 GO_REF:0000033 GO_REF:0000107 NCBI chr 7:10,011,065...10,016,841
Ensembl chr 7:10,011,066...10,016,665 		JBrowse link
G Gzmn granzyme N enables IBA
IEA 		GO_REF:0000033
GO_REF:0000002 		GO_Central
InterPro		 GO_REF:0000002 GO_REF:0000033 NCBI chr15:29,953,113...29,983,018
Ensembl chr15:29,953,123...29,983,009 		JBrowse link
G Habp2 hyaluronan binding protein 2 enables IEA
IBA 		GO_REF:0000002
GO_REF:0000033 		InterPro
GO_Central		 GO_REF:0000002 GO_REF:0000033 NCBI chr 1:255,315,870...255,350,161
Ensembl chr 1:255,315,915...255,350,160 		JBrowse link
G Hgf hepatocyte growth factor enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 4:18,673,736...18,745,582
Ensembl chr 4:18,677,101...18,745,409 		JBrowse link
G Hgfac HGF activator enables IBA
IEA 		GO_REF:0000033
GO_REF:0000002 		GO_Central
InterPro		 GO_REF:0000002 GO_REF:0000033 NCBI chr14:75,707,588...75,714,182
Ensembl chr14:75,707,591...75,714,278 		JBrowse link
G Hp haptoglobin enables IEA
IBA 		GO_REF:0000002
GO_REF:0000033 		InterPro
GO_Central		 GO_REF:0000002 GO_REF:0000033 NCBI chr19:37,539,626...37,544,178
Ensembl chr19:37,539,627...37,544,523 		JBrowse link
G Hpn hepsin enables ISO
IEA 		(PMID:16908524)
GO_REF:0000107
GO_REF:0000002 		RGD
Ensembl
InterPro		 PMID:16908524 GO_REF:0000002 GO_REF:0000107 NCBI chr 1:86,337,085...86,352,785
Ensembl chr 1:86,337,087...86,352,811 		JBrowse link
G Htra1 HtrA serine peptidase 1 enables IEA
IBA 		GO_REF:0000002
GO_REF:0000033 		InterPro
GO_Central		 GO_REF:0000002 GO_REF:0000033 NCBI chr 1:185,497,815...185,547,380
Ensembl chr 1:185,497,735...185,547,379 		JBrowse link
G Htra2 HtrA serine peptidase 2 enables ISO
IBA
IEA 		(PMID:10971580), (PMID:11602612), (PMID:11967569), (PMID:17297443), (PMID:25118933)
GO_REF:0000033
GO_REF:0000002
GO_REF:0000107 		RGD
GO_Central
InterPro
Ensembl		 PMID:10971580 PMID:11602612 PMID:11967569 PMID:17297443 PMID:25118933 GO_REF:0000002 GO_REF:0000033 GO_REF:0000107 NCBI chr 4:115,556,914...115,560,202
Ensembl chr 4:115,556,916...115,560,095 		JBrowse link
G Htra3 HtrA serine peptidase 3 enables IBA
IEA 		GO_REF:0000033
GO_REF:0000002 		GO_Central
InterPro		 GO_REF:0000002 GO_REF:0000033 NCBI chr14:75,068,917...75,097,315
Ensembl chr14:75,068,917...75,097,315 		JBrowse link
G Htra4 HtrA serine peptidase 4 enables IEA
IBA 		GO_REF:0000002
GO_REF:0000033 		InterPro
GO_Central		 GO_REF:0000002 GO_REF:0000033 NCBI chr16:67,001,605...67,015,074
Ensembl chr16:67,001,605...67,015,074 		JBrowse link
G Immp1l inner mitochondrial membrane peptidase subunit 1 enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 3:92,385,329...92,449,559
Ensembl chr 3:92,385,379...92,452,313 		JBrowse link
G Immp2l inner mitochondrial membrane peptidase subunit 2 enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 6:63,797,189...64,696,906
Ensembl chr 6:58,070,283...58,969,840 		JBrowse link
G Klk1 kallikrein 1 enables IBA
IEA 		GO_REF:0000033
GO_REF:0000003
GO_REF:0000002 		GO_Central
UniProt
InterPro		 GO_REF:0000002 GO_REF:0000003 GO_REF:0000033 NCBI chr 1:94,642,644...94,646,760
Ensembl chr 1:94,642,687...94,646,754 		JBrowse link
G Klk10 kallikrein related-peptidase 10 enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 1:94,234,536...94,239,369
Ensembl chr 1:94,235,096...94,239,376 		JBrowse link
G Klk11 kallikrein related-peptidase 11 enables IBA
IEA 		GO_REF:0000033
GO_REF:0000002 		GO_Central
InterPro		 GO_REF:0000002 GO_REF:0000033 NCBI chr 1:94,228,741...94,233,281
Ensembl chr 1:94,228,741...94,233,281 		JBrowse link
G Klk12 kallikrein related-peptidase 12 enables IBA
IEA 		GO_REF:0000033
GO_REF:0000002 		GO_Central
InterPro		 GO_REF:0000002 GO_REF:0000033 NCBI chr 1:94,222,778...94,227,637
Ensembl chr 1:94,223,045...94,227,637 		JBrowse link
G Klk13 kallikrein related-peptidase 13 enables IBA
IEA 		GO_REF:0000033
GO_REF:0000002 		GO_Central
InterPro		 GO_REF:0000002 GO_REF:0000033 NCBI chr 1:94,165,381...94,177,002
Ensembl chr 1:94,165,381...94,177,002 		JBrowse link
G Klk14 kallikrein related-peptidase 14 enables ISO
IBA
IEA 		(PMID:15654974), (PMID:16885167), (PMID:17110383), (PMID:17158887)
GO_REF:0000033
GO_REF:0000002 		RGD
GO_Central
InterPro		 PMID:15654974 PMID:16885167 PMID:17110383 PMID:17158887 GO_REF:0000002 GO_REF:0000033 NCBI chr 1:94,123,131...94,137,239
Ensembl chr 1:94,131,998...94,137,240 		JBrowse link
G Klk15 kallikrein-related peptidase 15 enables IBA
IEA 		GO_REF:0000033
GO_REF:0000002 		GO_Central
InterPro		 GO_REF:0000002 GO_REF:0000033 NCBI chr 1:94,699,422...94,706,626
Ensembl chr 1:94,703,158...94,706,329
Ensembl chr 1:94,703,158...94,706,329 		JBrowse link
G Klk1b3 kallikrein 1-related peptidase B3 enables IEA
IBA 		GO_REF:0000002
GO_REF:0000033
GO_REF:0000003 		InterPro
GO_Central
UniProt		 GO_REF:0000002 GO_REF:0000003 GO_REF:0000033 NCBI chr 1:94,709,105...94,713,308
Ensembl chr 1:94,709,105...94,713,308 		JBrowse link
G Klk1c10 kallikrein 1-related peptidase C10 enables ISO
IBA
IEA 		(PMID:15563730)
GO_REF:0000033
GO_REF:0000003
GO_REF:0000002 		RGD
GO_Central
UniProt
InterPro		 PMID:15563730 GO_REF:0000002 GO_REF:0000003 GO_REF:0000033 NCBI chr 1:103,539,527...103,543,586
Ensembl chr 1:94,402,993...94,407,052 		JBrowse link
G Klk1c12 kallikrein 1-related peptidase C12 enables TAS
IEA
IBA 		GO_REF:0000002
GO_REF:0000033
GO_REF:0000003 		InterPro
GO_Central
UniProt
RGD		 PMID:15203212 PMID:8662704 GO_REF:0000002 GO_REF:0000003 GO_REF:0000033, RGD:1304003, RGD:1304014 NCBI chr 1:94,378,103...94,382,140
Ensembl chr 1:94,378,054...94,382,176 		JBrowse link
G Klk1c2 kallikrein 1-related peptidase C2 enables IEA
IBA 		GO_REF:0000002
GO_REF:0000033
GO_REF:0000003 		InterPro
GO_Central
UniProt		 GO_REF:0000002 GO_REF:0000003 GO_REF:0000033 NCBI chr 1:94,492,332...94,496,480
Ensembl chr 1:94,492,332...94,496,481 		JBrowse link
G Klk1c3 kallikrein 1-related peptidase C3 enables IBA
IEA 		GO_REF:0000033
GO_REF:0000002
GO_REF:0000003 		GO_Central
InterPro
UniProt		 GO_REF:0000002 GO_REF:0000003 GO_REF:0000033 NCBI chr 1:94,671,636...94,675,417
Ensembl chr 1:94,671,618...94,675,417 		JBrowse link
G Klk1c4 kallikrein 1-related peptidase C4 enables IBA
IEA 		GO_REF:0000033
GO_REF:0000002 		GO_Central
InterPro		 GO_REF:0000002 GO_REF:0000033 NCBI chr 1:94,434,574...94,438,678
Ensembl chr 1:94,434,534...94,438,709 		JBrowse link
G Klk1c6 kallikrein 1-related peptidase C6 enables IBA
IEA 		GO_REF:0000033
GO_REF:0000002 		GO_Central
InterPro		 GO_REF:0000002 GO_REF:0000033 NCBI chr 1:94,467,626...94,475,842
Ensembl chr 1:94,467,672...94,475,806 		JBrowse link
G Klk1c8 kallikrein 1-related peptidase C8 enables IEA
IBA 		GO_REF:0000002
GO_REF:0000033
GO_REF:0000003 		InterPro
GO_Central
UniProt		 GO_REF:0000002 GO_REF:0000003 GO_REF:0000033 NCBI chr 1:94,547,774...94,552,287
Ensembl chr 1:94,547,774...94,551,636 		JBrowse link
G Klk1c9 kallikrein 1-related peptidase C9 enables IEA
IBA 		GO_REF:0000002
GO_REF:0000033
GO_REF:0000003 		InterPro
GO_Central
UniProt		 GO_REF:0000002 GO_REF:0000003 GO_REF:0000033 NCBI chr 1:94,597,359...94,601,245
Ensembl chr 1:94,597,359...94,601,245 		JBrowse link
G Klk4 kallikrein-related peptidase 4 enables IBA
IEA 		GO_REF:0000033
GO_REF:0000002 		GO_Central
InterPro		 GO_REF:0000002 GO_REF:0000033 NCBI chr 1:94,344,195...94,349,425
Ensembl chr 1:94,344,195...94,349,424 		JBrowse link
G Klk5 kallikrein related-peptidase 5 enables ISO
IBA
IEA 		(PMID:16885167)
GO_REF:0000033
GO_REF:0000002
GO_REF:0000107 		RGD
GO_Central
InterPro
Ensembl		 PMID:16885167 GO_REF:0000002 GO_REF:0000033 GO_REF:0000107 NCBI chr 1:94,296,574...94,304,768
Ensembl chr 1:94,296,168...94,304,666 		JBrowse link
G Klk6 kallikrein related-peptidase 6 enables ISO
IBA
IEA 		(PMID:16885167)
GO_REF:0000033
GO_REF:0000002
GO_REF:0000107 		RGD
GO_Central
InterPro
Ensembl		 PMID:16885167 GO_REF:0000002 GO_REF:0000033 GO_REF:0000107 NCBI chr 1:94,278,863...94,286,136
Ensembl chr 1:94,280,340...94,286,121 		JBrowse link
G Klk7 kallikrein-related peptidase 7 enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 1:94,267,170...94,271,361
Ensembl chr 1:94,266,605...94,271,332 		JBrowse link
G Klk8 kallikrein related-peptidase 8 enables ISO
ISS
IEA
IBA 		(PMID:16337200)
GO_REF:0000024
GO_REF:0000107
(PMID:12944500), (PMID:9556608)
GO_REF:0000033
GO_REF:0000002 		RGD
UniProt
Ensembl
GO_Central
InterPro		 PMID:9556608 PMID:12944500 PMID:16337200 GO_REF:0000002 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr 1:94,251,803...94,258,646
Ensembl chr 1:94,251,803...94,258,646 		JBrowse link
G Klk9 kallikrein related-peptidase 9 enables IBA
IEA 		GO_REF:0000033
GO_REF:0000002 		GO_Central
InterPro		 GO_REF:0000002 GO_REF:0000033 NCBI chr 1:94,246,339...94,250,631
Ensembl chr 1:94,246,339...94,250,631 		JBrowse link
G Klkb1 kallikrein B1 enables IEA GO_REF:0000003
GO_REF:0000002 		UniProt
InterPro		 GO_REF:0000002 GO_REF:0000003 NCBI chr16:46,958,634...46,982,054
Ensembl chr16:46,958,707...46,982,053 		JBrowse link
G LOC100361261 uncharacterized LOC100361261 enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr15:30,173,597...30,176,533
Ensembl chr15:30,087,127...30,206,702 		JBrowse link
G LOC100912724 mast cell protease 8-like enables IEA GO_REF:0000002 InterPro GO_REF:0000002
G LOC102553861 granzyme-like protein 1-like enables IEA
IBA 		GO_REF:0000002
GO_REF:0000033 		InterPro
GO_Central		 GO_REF:0000002 GO_REF:0000033 NCBI chr15:30,218,338...30,220,571
Ensembl chr15:30,173,603...30,346,814 		JBrowse link
G LOC102554637 anionic trypsin-2-like enables IBA
IEA 		GO_REF:0000033
GO_REF:0000002 		GO_Central
InterPro		 GO_REF:0000002 GO_REF:0000033 NCBI chr 4:70,331,673...70,335,768
Ensembl chr 4:70,331,673...70,335,933 		JBrowse link
G LOC103690372 granzyme B-like enables IEA GO_REF:0000002 InterPro GO_REF:0000002
G LOC134481969 granzyme-like protein 2 enables IEA GO_REF:0000002 InterPro GO_REF:0000002
G LOC134481973 mast cell protease 1-like enables IBA
IEA 		GO_REF:0000033
GO_REF:0000002 		GO_Central
InterPro		 GO_REF:0000002 GO_REF:0000033
G LOC134482223 mast cell protease 4-like enables IBA
IEA 		GO_REF:0000033
GO_REF:0000002 		GO_Central
InterPro		 GO_REF:0000002 GO_REF:0000033
G Lonp1 lon peptidase 1, mitochondrial enables IEA GO_REF:0000003
GO_REF:0000104
GO_REF:0000002 		UniProt
InterPro		 GO_REF:0000002 GO_REF:0000003 GO_REF:0000104 NCBI chr 9:1,447,444...1,459,771
Ensembl chr 9:1,447,447...1,459,771 		JBrowse link
G Lonp2 lon peptidase 2, peroxisomal enables IEA GO_REF:0000002
GO_REF:0000003
GO_REF:0000104 		InterPro
UniProt		 GO_REF:0000002 GO_REF:0000003 GO_REF:0000104 NCBI chr19:20,407,475...20,498,985
Ensembl chr19:20,407,477...20,499,014 		JBrowse link
G Masp1 MBL associated serine protease 1 enables ISO
IDA
IBA
IEA 		(PMID:11527969)
PMID:15060079
GO_REF:0000033
(PMID:18424734)
GO_REF:0000002
GO_REF:0000107 		RGD
GO_Central
InterPro
Ensembl		 PMID:11527969 PMID:18424734 PMID:15060079 GO_REF:0000002 GO_REF:0000033 GO_REF:0000107, RGD:1600552 NCBI chr11:77,334,794...77,405,271
Ensembl chr11:77,334,859...77,402,974 		JBrowse link
G Masp2 MBL associated serine protease 2 enables ISO
IDA
IBA
IEA 		(PMID:9087411)
PMID:15060079
GO_REF:0000033
GO_REF:0000107
GO_REF:0000002 		RGD
GO_Central
Ensembl
InterPro		 PMID:9087411 PMID:15060079 GO_REF:0000002 GO_REF:0000033 GO_REF:0000107, RGD:1600552 NCBI chr 5:159,035,892...159,049,561
Ensembl chr 5:159,035,911...159,049,580 		JBrowse link
G Mbtps1 membrane-bound transcription factor peptidase, site 1 enables IDA
ISO
IEA
IBA 		(PMID:11163209), (PMID:21719679), (PMID:34349020)
GO_REF:0000104
GO_REF:0000033
(PMID:9990022)
GO_REF:0000107
GO_REF:0000002 		RGD
UniProt
GO_Central
Ensembl
InterPro		 PMID:9990022 PMID:11163209 PMID:21719679 PMID:34349020 PMID:9990022 GO_REF:0000002 GO_REF:0000033 GO_REF:0000104 GO_REF:0000107, RGD:70790 NCBI chr19:47,561,598...47,612,769
Ensembl chr19:47,561,598...47,612,791 		JBrowse link
G Mcpt1 mast cell protease 1 enables IBA
IEA 		GO_REF:0000033
GO_REF:0000002 		GO_Central
InterPro		 GO_REF:0000002 GO_REF:0000033 NCBI chr15:29,871,360...29,873,928
Ensembl chr15:29,871,335...29,873,926 		JBrowse link
G Mcpt10 mast cell protease 10 enables IEA
IBA 		GO_REF:0000002
GO_REF:0000033 		InterPro
GO_Central		 GO_REF:0000002 GO_REF:0000033 NCBI chr15:29,915,483...29,918,540
Ensembl chr15:29,915,483...29,918,511 		JBrowse link
G Mcpt1l1 mast cell protease 1-like 1 enables IBA
IEA 		GO_REF:0000033
GO_REF:0000002
GO_REF:0000003 		GO_Central
InterPro
UniProt		 GO_REF:0000002 GO_REF:0000003 GO_REF:0000033 NCBI chr15:29,903,993...29,906,649
Ensembl chr15:29,903,980...29,906,645 		JBrowse link
G Mcpt1l3 mast cell protease 1-like 3 enables IBA
IEA 		GO_REF:0000033
GO_REF:0000002 		GO_Central
InterPro		 GO_REF:0000002 GO_REF:0000033 NCBI chr15:29,836,398...29,841,731
Ensembl chr15:29,532,079...29,873,922 		JBrowse link
G Mcpt3 mast cell peptidase 3 enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr15:29,532,053...29,534,684
Ensembl chr15:29,532,079...29,873,922 		JBrowse link
G Mcpt4 mast cell protease 4 enables IDA
IBA
IEA 		GO_REF:0000033
GO_REF:0000002 		GO_Central
InterPro
RGD		 PMID:11896050 GO_REF:0000002 GO_REF:0000033, RGD:633287 NCBI chr15:29,501,595...29,504,216
Ensembl chr15:29,501,595...29,504,214 		JBrowse link
G Mcpt4l1 mast cell protease 4-like 1 enables IBA
IEA 		GO_REF:0000033
GO_REF:0000002 		GO_Central
InterPro		 GO_REF:0000002 GO_REF:0000033 NCBI chr15:29,450,677...29,453,073
Ensembl chr15:29,427,552...29,453,073 		JBrowse link
G Mcpt8 mast cell protease 8 enables IEA
IBA 		GO_REF:0000002
GO_REF:0000033 		InterPro
GO_Central		 GO_REF:0000002 GO_REF:0000033 NCBI chr15:29,799,328...29,802,387
Ensembl chr15:29,799,357...29,860,148 		JBrowse link
G Mcpt9 mast cell protease 9 enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr15:29,857,182...29,860,145
Ensembl chr15:29,799,357...29,860,148 		JBrowse link
G Mmp13 matrix metallopeptidase 13 enables TAS Reactome:R-NUL-2534170 Reactome Reactome:R-NUL-2534170 NCBI chr 8:4,497,960...4,508,239
Ensembl chr 8:4,497,960...4,508,239 		JBrowse link
G Mmp2 matrix metallopeptidase 2 enables ISO (PMID:17428795) RGD PMID:17428795 NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870 		JBrowse link
G Mmp8 matrix metallopeptidase 8 enables ISO
ISS
IEA 		(PMID:16192646), (PMID:2164002)
GO_REF:0000024
GO_REF:0000107 		RGD
UniProt
Ensembl		 PMID:2164002 PMID:16192646 GO_REF:0000024 GO_REF:0000107 NCBI chr 8:4,724,009...4,733,864
Ensembl chr 8:4,724,029...4,733,520 		JBrowse link
G Mmp9 matrix metallopeptidase 9 enables ISO (PMID:17428795) RGD PMID:17428795 NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120 		JBrowse link
G Ovch2 ovochymase 2 enables ISO
IEA 		(PMID:32499443)
GO_REF:0000002 		RGD
InterPro		 PMID:32499443 GO_REF:0000002 NCBI chr 1:161,693,619...161,713,952
Ensembl chr 1:161,693,647...161,713,952 		JBrowse link
G Pamr1 peptidase domain containing associated with muscle regeneration 1 enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 3:88,889,061...88,988,615
Ensembl chr 3:88,889,046...88,988,606 		JBrowse link
G Parl presenilin associated, rhomboid-like enables IEA
ISO
ISS
IBA 		GO_REF:0000002
(PMID:22915595)
GO_REF:0000024
GO_REF:0000033
GO_REF:0000107 		InterPro
RGD
UniProt
GO_Central
Ensembl		 PMID:22915595 GO_REF:0000002 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr11:80,594,059...80,620,506
Ensembl chr11:80,593,192...80,620,506 		JBrowse link
G Pcsk1 proprotein convertase subtilisin/kexin type 1 enables IBA
ISO
IEA 		GO_REF:0000033
MGI:2384741 (PMID:12136131), (PMID:8262946)
GO_REF:0000002
GO_REF:0000003 		GO_Central
RGD
InterPro
UniProt		 PMID:8262946 PMID:12136131 GO_REF:0000002 GO_REF:0000003 GO_REF:0000033 NCBI chr 2:4,395,543...4,442,434
Ensembl chr 2:4,395,543...4,442,434 		JBrowse link
G Pcsk2 proprotein convertase subtilisin/kexin type 2 enables IMP
EXP
ISO
IEA
IBA 		PMID:15983213
PMID:3283564
(PMID:7626024)
PMID:1429623
GO_REF:0000002
GO_REF:0000033
MGI:1857445 (PMID:8262946), (PMID:9452465)
GO_REF:0000003 		RGD
InterPro
GO_Central
UniProt		 PMID:7626024 PMID:8262946 PMID:9452465 PMID:15983213 PMID:3283564 More... GO_REF:0000002 GO_REF:0000003 GO_REF:0000033, RGD:8554260, RGD:13506270, RGD:13506272 NCBI chr 3:130,880,422...131,183,127
Ensembl chr 3:130,880,422...131,183,127 		JBrowse link
G Pcsk4 proprotein convertase subtilisin/kexin type 4 enables IEA
IBA 		GO_REF:0000104
GO_REF:0000033
GO_REF:0000002 		UniProt
GO_Central
InterPro		 GO_REF:0000002 GO_REF:0000033 GO_REF:0000104 NCBI chr 7:9,381,366...9,389,589
Ensembl chr 7:9,381,361...9,389,585 		JBrowse link
G Pcsk5 proprotein convertase subtilisin/kexin type 5 enables ISO
IEA
IBA 		(PMID:8901832)
GO_REF:0000104
GO_REF:0000033
(PMID:8468318)
GO_REF:0000002
GO_REF:0000107 		RGD
UniProt
GO_Central
InterPro
Ensembl		 PMID:8468318 PMID:8901832 GO_REF:0000002 GO_REF:0000033 GO_REF:0000104 GO_REF:0000107 NCBI chr 1:214,837,847...215,267,626
Ensembl chr 1:214,837,927...215,267,600 		JBrowse link
G Pcsk6 proprotein convertase subtilisin/kexin type 6 enables ISO
IEA
IBA 		(PMID:8218226), (PMID:8615794), (PMID:8906861)
GO_REF:0000104
GO_REF:0000033
GO_REF:0000107
GO_REF:0000002 		RGD
UniProt
GO_Central
Ensembl
InterPro		 PMID:8218226 PMID:8615794 PMID:8906861 GO_REF:0000002 GO_REF:0000033 GO_REF:0000104 GO_REF:0000107 NCBI chr 1:128,839,742...129,038,087
Ensembl chr 1:119,429,265...119,627,596 		JBrowse link
G Pcsk7 proprotein convertase subtilisin/kexin type 7 enables IBA
IEA 		GO_REF:0000033
GO_REF:0000002 		GO_Central
InterPro		 GO_REF:0000002 GO_REF:0000033 NCBI chr 8:46,202,079...46,224,699
Ensembl chr 8:46,202,131...46,224,705 		JBrowse link
G Pcsk9 proprotein convertase subtilisin/kexin type 9 enables ISO
ISS
IBA
IEA 		(PMID:12552133)
GO_REF:0000033
GO_REF:0000002
GO_REF:0000107 		RGD
GO_Central
InterPro
Ensembl		 PMID:12552133 PMID:12552133 GO_REF:0000002 GO_REF:0000033 GO_REF:0000107, RGD:629554 NCBI chr 5:121,211,278...121,233,688
Ensembl chr 5:121,211,278...121,233,688 		JBrowse link
G Plat plasminogen activator, tissue type enables ISO
IEA
IBA 		(PMID:1695900), (PMID:8508955)
GO_REF:0000104
GO_REF:0000107
GO_REF:0000033
(PMID:15372073)
GO_REF:0000002
GO_REF:0000003 		RGD
UniProt
Ensembl
GO_Central
InterPro		 PMID:1695900 PMID:8508955 PMID:15372073 GO_REF:0000002 GO_REF:0000003 GO_REF:0000033 GO_REF:0000104 GO_REF:0000107 NCBI chr16:69,240,582...69,265,177
Ensembl chr16:69,240,585...69,268,223 		JBrowse link
G Plau plasminogen activator, urokinase enables IEA
IBA 		GO_REF:0000002
GO_REF:0000033
GO_REF:0000003 		InterPro
GO_Central
UniProt		 GO_REF:0000002 GO_REF:0000003 GO_REF:0000033 NCBI chr15:3,456,230...3,462,732
Ensembl chr15:3,456,232...3,462,775 		JBrowse link
G Plg plasminogen enables ISO
IEA 		(PMID:14688145), (PMID:14699093), (PMID:17307854), (PMID:18070902), (PMID:19270100), (PMID:20727989)
GO_REF:0000104
GO_REF:0000002
GO_REF:0000003 		RGD
UniProt
InterPro		 PMID:14688145 PMID:14699093 PMID:17307854 PMID:18070902 PMID:19270100 More... GO_REF:0000002 GO_REF:0000003 GO_REF:0000104 NCBI chr 1:48,325,186...48,367,643
Ensembl chr 1:48,325,185...48,367,786 		JBrowse link
G Prep prolyl endopeptidase enables IEA GO_REF:0000003
GO_REF:0000104
GO_REF:0000002 		UniProt
InterPro		 GO_REF:0000002 GO_REF:0000003 GO_REF:0000104 NCBI chr20:48,556,211...48,653,165
Ensembl chr20:48,556,280...48,654,466 		JBrowse link
G Prepl prolyl endopeptidase-like enables IEA GO_REF:0000002
GO_REF:0000104 		InterPro
UniProt		 GO_REF:0000002 GO_REF:0000104 NCBI chr 6:9,580,367...9,609,957
Ensembl chr 6:9,580,217...9,607,772 		JBrowse link
G Proc protein C, inactivator of coagulation factors Va and VIIIa enables ISS
ISO
IBA
IEA 		GO_REF:0000024
(PMID:25748729)
GO_REF:0000033
GO_REF:0000002
GO_REF:0000003 		UniProt
RGD
GO_Central
InterPro		 PMID:25748729 GO_REF:0000002 GO_REF:0000003 GO_REF:0000024 GO_REF:0000033 NCBI chr18:23,764,367...23,774,816
Ensembl chr18:23,764,368...23,775,133 		JBrowse link
G Proz protein Z, vitamin K-dependent plasma glycoprotein enables IBA
IEA 		GO_REF:0000033
GO_REF:0000002 		GO_Central
InterPro		 GO_REF:0000002 GO_REF:0000033 NCBI chr16:76,450,013...76,463,558
Ensembl chr16:76,450,013...76,463,480 		JBrowse link
G Prrg1 proline rich and Gla domain 1 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr  X:42,494,256...42,606,612
Ensembl chr  X:42,494,256...42,606,588 		JBrowse link
G Prrg2 proline rich and Gla domain 2 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:95,534,276...95,543,364
Ensembl chr 1:95,534,290...95,543,425 		JBrowse link
G Prrg3 proline rich and Gla domain 3 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr  X:149,666,498...149,689,353
Ensembl chr  X:149,670,257...149,677,373 		JBrowse link
G Prrg4 proline rich and Gla domain 4 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 3:91,214,646...91,243,347
Ensembl chr 3:91,214,653...91,243,273 		JBrowse link
G Prss1 serine protease 1 enables IBA
IEA 		GO_REF:0000033
GO_REF:0000107
GO_REF:0000002
GO_REF:0000003 		GO_Central
Ensembl
InterPro
UniProt		 GO_REF:0000002 GO_REF:0000003 GO_REF:0000033 GO_REF:0000107 NCBI chr 4:70,364,589...70,367,792
Ensembl chr 4:70,364,586...70,367,792 		JBrowse link
G Prss12 serine protease 12 enables ISO
IEA 		(PMID:17223089)
GO_REF:0000002 		RGD
InterPro		 PMID:17223089 GO_REF:0000002 NCBI chr 2:211,624,134...211,684,126
Ensembl chr 2:211,624,134...211,684,126 		JBrowse link
G Prss2 protease, serine, 2 enables ISS
IBA
IEA 		GO_REF:0000024
GO_REF:0000033
GO_REF:0000002
GO_REF:0000003 		UniProt
GO_Central
InterPro		 GO_REF:0000002 GO_REF:0000003 GO_REF:0000024 GO_REF:0000033 NCBI chr 4:70,278,304...70,283,385
Ensembl chr 4:70,278,304...70,283,385 		JBrowse link
G Prss21 serine protease 21 enables ISO
IBA
IEA 		(PMID:11861648)
GO_REF:0000033
GO_REF:0000107
GO_REF:0000002 		RGD
GO_Central
Ensembl
InterPro		 PMID:11861648 GO_REF:0000002 GO_REF:0000033 GO_REF:0000107 NCBI chr10:12,899,820...12,905,612
Ensembl chr10:12,900,535...12,905,618 		JBrowse link
G Prss22 serine protease 22 enables ISO
IEA 		(PMID:11602603)
GO_REF:0000002 		RGD
InterPro		 PMID:11602603 GO_REF:0000002 NCBI chr10:13,029,153...13,033,863
Ensembl chr10:13,029,153...13,033,863 		JBrowse link
G Prss23 serine protease 23 enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 1:143,402,725...143,422,182
Ensembl chr 1:143,401,396...143,422,091 		JBrowse link
G Prss27 serine protease 27 enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr10:13,069,959...13,077,322
Ensembl chr10:13,069,959...13,077,322 		JBrowse link
G Prss28l-ps1 protease, serine 28 like, pseudogene 1 enables IBA
IEA 		GO_REF:0000033
GO_REF:0000002 		GO_Central
InterPro		 GO_REF:0000002 GO_REF:0000033 NCBI chr10:14,327,441...14,329,741
Ensembl chr10:14,327,462...14,329,741 		JBrowse link
G Prss29 serine protease 29 enables IBA
IEA 		GO_REF:0000033
GO_REF:0000002 		GO_Central
InterPro		 GO_REF:0000002 GO_REF:0000033 NCBI chr10:14,337,315...14,341,038
Ensembl chr10:14,339,036...14,341,038 		JBrowse link
G Prss29-ps1 serine protease 29, pseudogene 1 enables IBA
IEA 		GO_REF:0000033
GO_REF:0000002 		GO_Central
InterPro		 GO_REF:0000002 GO_REF:0000033 NCBI chr10:14,347,744...14,350,247
Ensembl chr10:14,347,327...14,350,598 		JBrowse link
G Prss2l1 protease, serine, 2 like 1 enables IBA
IEA 		GO_REF:0000033
GO_REF:0000002 		GO_Central
InterPro		 GO_REF:0000002 GO_REF:0000033 NCBI chr 4:70,344,338...70,348,069
Ensembl chr 4:70,344,338...70,348,006 		JBrowse link
G Prss3 serine protease 3 enables ISO
IBA
IEA 		(PMID:11827488), (PMID:14507909), (PMID:25301953), (PMID:6698368)
GO_REF:0000033
(PMID:23814066)
GO_REF:0000002 		RGD
GO_Central
InterPro		 PMID:6698368 PMID:11827488 PMID:14507909 PMID:23814066 PMID:25301953 GO_REF:0000002 GO_REF:0000033 NCBI chr 4:70,203,088...70,206,562
Ensembl chr 4:70,203,088...70,206,562 		JBrowse link
G Prss30 protease, serine, 30 enables IDA
IEA
IBA 		PMID:14669991
GO_REF:0000002
GO_REF:0000033 		InterPro
GO_Central		 PMID:14669991 GO_REF:0000002 GO_REF:0000033, RGD:8554420 NCBI chr10:13,007,341...13,014,827
Ensembl chr10:13,007,341...13,011,030 		JBrowse link
G Prss32 protease, serine, 32 enables IBA
IEA 		GO_REF:0000033
GO_REF:0000002 		GO_Central
InterPro		 GO_REF:0000002 GO_REF:0000033 NCBI chr10:12,882,504...12,888,600
Ensembl chr10:12,882,504...12,888,600 		JBrowse link
G Prss33 serine protease 33 enables IBA
IEA 		GO_REF:0000033
GO_REF:0000002 		GO_Central
InterPro		 GO_REF:0000002 GO_REF:0000033 NCBI chr10:12,858,941...12,861,281
Ensembl chr10:12,858,941...12,861,281 		JBrowse link
G Prss34 protease, serine, 34 enables IBA
IEA 		GO_REF:0000033
GO_REF:0000002 		GO_Central
InterPro		 GO_REF:0000002 GO_REF:0000033 NCBI chr10:14,315,913...14,317,712
Ensembl chr10:14,315,955...14,317,712 		JBrowse link
G Prss35 serine protease 35 enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 8:87,714,449...87,731,009
Ensembl chr 8:87,714,966...87,731,009 		JBrowse link
G Prss36 serine protease 36 enables IEA
ISO
IBA 		GO_REF:0000104
(PMID:15536082)
GO_REF:0000002
GO_REF:0000033 		UniProt
RGD
InterPro
GO_Central		 PMID:15536082 GO_REF:0000002 GO_REF:0000033 GO_REF:0000104 NCBI chr 1:182,543,085...182,561,141
Ensembl chr 1:182,543,085...182,559,280 		JBrowse link
G Prss37 serine protease 37 NOT|enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 4:69,322,977...69,334,555
Ensembl chr 4:69,322,977...69,334,555 		JBrowse link
G Prss38 serine protease 38 enables IBA
IEA 		GO_REF:0000033
GO_REF:0000002 		GO_Central
InterPro		 GO_REF:0000002 GO_REF:0000033 NCBI chr10:44,159,339...44,163,019
Ensembl chr10:44,159,346...44,162,488 		JBrowse link
G Prss39 protease, serine, 39 enables IBA
IEA 		GO_REF:0000033
GO_REF:0000002 		GO_Central
InterPro		 GO_REF:0000002 GO_REF:0000033 NCBI chr 9:36,695,037...36,713,004
Ensembl chr 9:36,707,328...36,713,001 		JBrowse link
G Prss3b protease, serine, 3B enables IBA
IEA 		GO_REF:0000033
GO_REF:0000107
GO_REF:0000002
GO_REF:0000003 		GO_Central
Ensembl
InterPro
UniProt		 GO_REF:0000002 GO_REF:0000003 GO_REF:0000033 GO_REF:0000107 NCBI chr 4:69,871,810...69,875,518
Ensembl chr 4:69,871,797...69,875,549 		JBrowse link
G Prss3bl1 protease, serine, 3B like 1 enables IBA
IEA 		GO_REF:0000033
GO_REF:0000002
GO_REF:0000003 		GO_Central
InterPro
UniProt		 GO_REF:0000002 GO_REF:0000003 GO_REF:0000033 NCBI chr 4:69,797,661...69,803,606
Ensembl chr 4:69,797,661...69,803,606 		JBrowse link
G Prss40 protease, serine, 40 enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 9:36,762,170...36,770,979
Ensembl chr 9:36,762,173...36,770,979 		JBrowse link
G Prss41 serine protease 41 enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr10:12,865,872...12,873,552
Ensembl chr10:12,865,872...12,873,552 		JBrowse link
G Prss42 serine protease 42 enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 8:110,772,748...110,777,947
Ensembl chr 8:110,772,625...110,777,947 		JBrowse link
G Prss44 serine protease 44 enables IBA
IEA 		GO_REF:0000033
GO_REF:0000002 		GO_Central
InterPro		 GO_REF:0000002 GO_REF:0000033 NCBI chr 8:110,791,698...110,805,303
Ensembl chr 8:110,791,698...110,805,303 		JBrowse link
G Prss45 serine protease 45 enables TAS
IEA
IBA 		GO_REF:0000002
GO_REF:0000033 		InterPro
GO_Central
RGD		 PMID:15060002 GO_REF:0000002 GO_REF:0000033, RGD:1303943 NCBI chr 8:110,820,301...110,826,080
Ensembl chr 8:110,820,273...110,826,120 		JBrowse link
G Prss46 protease, serine, 46 enables IBA
IEA 		GO_REF:0000033
GO_REF:0000002 		GO_Central
InterPro		 GO_REF:0000002 GO_REF:0000033 NCBI chr 8:110,829,275...110,841,049
Ensembl chr 8:110,829,266...110,841,123 		JBrowse link
G Prss47 serine protease 47 enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr17:139,835...154,263
Ensembl chr17:140,603...154,261 		JBrowse link
G Prss48 serine protease 48 enables IBA
IEA 		GO_REF:0000033
GO_REF:0000002 		GO_Central
InterPro		 GO_REF:0000002 GO_REF:0000033 NCBI chr 2:171,358,946...171,387,051
Ensembl chr 2:171,377,970...171,387,020 		JBrowse link
G Prss50 serine protease 50 enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 8:110,842,525...110,848,855
Ensembl chr 8:110,842,671...110,848,802 		JBrowse link
G Prss51 serine protease 51 enables IBA
IEA 		GO_REF:0000033
GO_REF:0000002 		GO_Central
InterPro		 GO_REF:0000002 GO_REF:0000033 NCBI chr15:38,331,545...38,337,878
Ensembl chr15:38,333,963...38,337,883 		JBrowse link
G Prss52 protease, serine 52 enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr15:38,344,486...38,353,316
Ensembl chr15:38,344,513...38,353,325 		JBrowse link
G Prss53 serine protease 53 enables IBA
IEA 		GO_REF:0000033
GO_REF:0000002 		GO_Central
InterPro		 GO_REF:0000002 GO_REF:0000033 NCBI chr 1:182,494,944...182,501,607
Ensembl chr 1:182,494,955...182,500,115 		JBrowse link
G Prss54 serine protease 54 enables IEA
IBA 		GO_REF:0000002
GO_REF:0000033 		InterPro
GO_Central		 GO_REF:0000002 GO_REF:0000033 NCBI chr19:9,479,995...9,496,838
Ensembl chr19:9,479,995...9,496,835 		JBrowse link
G Prss55 serine protease 55 enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr15:38,297,674...38,345,059
Ensembl chr15:38,312,982...38,323,103 		JBrowse link
G Prss56 serine protease 56 enables ISO
IBA
IEA 		(PMID:21532570)
GO_REF:0000033
GO_REF:0000107
GO_REF:0000002 		RGD
GO_Central
Ensembl
InterPro		 PMID:21532570 GO_REF:0000002 GO_REF:0000033 GO_REF:0000107 NCBI chr 9:87,842,806...87,859,978
Ensembl chr 9:87,854,805...87,859,978 		JBrowse link
G Prss57 serine protease 57 enables IEA
IBA 		GO_REF:0000002
GO_REF:0000033 		InterPro
GO_Central		 GO_REF:0000002 GO_REF:0000033 NCBI chr 7:9,915,667...9,922,996
Ensembl chr 7:9,917,484...9,922,922 		JBrowse link
G Prss58 serine protease 58 enables IBA
IEA 		GO_REF:0000033
GO_REF:0000002
GO_REF:0000003 		GO_Central
InterPro
UniProt		 GO_REF:0000002 GO_REF:0000003 GO_REF:0000033 NCBI chr 4:69,752,646...69,757,306
Ensembl chr 4:69,752,573...69,756,962 		JBrowse link
G Prss59 protease, serine 59 enables IBA
IEA 		GO_REF:0000033
GO_REF:0000002 		GO_Central
InterPro		 GO_REF:0000002 GO_REF:0000033 NCBI chr 4:69,764,206...69,785,111
Ensembl chr 4:69,764,193...69,782,159 		JBrowse link
G Prss8 serine protease 8 enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 1:182,536,229...182,540,745
Ensembl chr 1:182,536,229...182,540,815 		JBrowse link
G Prtn3 proteinase 3 enables ISO
IBA
IEA 		(PMID:11389039), (PMID:22266279), (PMID:23202369), (PMID:28240246)
GO_REF:0000033
GO_REF:0000002 		RGD
GO_Central
InterPro		 PMID:11389039 PMID:22266279 PMID:23202369 PMID:28240246 GO_REF:0000002 GO_REF:0000033 NCBI chr 7:9,822,123...9,831,300
Ensembl chr 7:9,822,122...9,831,944 		JBrowse link
G Psmb10 proteasome 20S subunit beta 10 enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr19:33,830,958...33,833,442
Ensembl chr19:33,827,229...33,833,626 		JBrowse link
G Rhbdd1 rhomboid domain containing 1 enables ISO
ISS
IEA
IBA 		(PMID:18953687)
GO_REF:0000002
GO_REF:0000033 		RGD
InterPro
GO_Central		 PMID:18953687 PMID:18953687 GO_REF:0000002 GO_REF:0000033, RGD:8554435 NCBI chr 9:83,630,037...83,748,690
Ensembl chr 9:83,630,063...83,748,689 		JBrowse link
G Rhbdd2 rhomboid domain containing 2 enables IBA
IEA 		GO_REF:0000033
GO_REF:0000002 		GO_Central
InterPro		 GO_REF:0000002 GO_REF:0000033 NCBI chr12:21,043,605...21,054,305
Ensembl chr12:21,043,608...21,054,289 		JBrowse link
G Rhbdd3 rhomboid domain containing 3 enables IBA
IEA 		GO_REF:0000033
GO_REF:0000002 		GO_Central
InterPro		 GO_REF:0000002 GO_REF:0000033 NCBI chr14:79,994,111...80,000,294
Ensembl chr14:79,994,158...80,000,175 		JBrowse link
G Rhbdf1 rhomboid 5 homolog 1 NOT|enables ISO
IBA 		(PMID:21439629)
GO_REF:0000033 		RGD
GO_Central		 PMID:21439629 GO_REF:0000033 NCBI chr10:15,406,832...15,419,765
Ensembl chr10:15,406,859...15,419,763 		JBrowse link
G Rhbdf2 rhomboid 5 homolog 2 NOT|enables ISO
IBA 		(PMID:21439629)
GO_REF:0000033 		RGD
GO_Central		 PMID:21439629 GO_REF:0000033 NCBI chr10:101,833,157...101,860,283
Ensembl chr10:101,833,157...101,860,283 		JBrowse link
G Rhbdl1 rhomboid like 1 enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr10:14,854,514...14,858,848
Ensembl chr10:14,854,514...14,857,430 		JBrowse link
G Rhbdl2 rhomboid like 2 enables ISO
IBA
IEA 		(PMID:19850051)
(PMID:21439629)
GO_REF:0000033
GO_REF:0000104
GO_REF:0000002 		RGD
GO_Central
UniProt
InterPro		 PMID:19850051 PMID:21439629 GO_REF:0000002 GO_REF:0000033 GO_REF:0000104 NCBI chr 5:136,037,560...136,081,970
Ensembl chr 5:136,037,305...136,081,969 		JBrowse link
G Rhbdl3 rhomboid like 3 enables IBA
IEA 		GO_REF:0000033
GO_REF:0000104
GO_REF:0000002 		GO_Central
UniProt
InterPro		 GO_REF:0000002 GO_REF:0000033 GO_REF:0000104 NCBI chr10:65,299,250...65,354,099
Ensembl chr10:65,299,194...65,354,099 		JBrowse link
G Sec11a SEC11 homolog A, signal peptidase complex subunit enables ISO
ISS
IEA 		(PMID:34388369)
GO_REF:0000024
GO_REF:0000002
GO_REF:0000107
GO_REF:0000003 		RGD
UniProt
InterPro
Ensembl		 PMID:34388369 GO_REF:0000002 GO_REF:0000003 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:134,881,448...134,909,427
Ensembl chr 1:134,875,265...134,915,069 		JBrowse link
G Sec11c SEC11 homolog C, signal peptidase complex subunit enables IEA
ISO
ISS 		GO_REF:0000003
(PMID:34388369)
GO_REF:0000024
GO_REF:0000002
GO_REF:0000107 		UniProt
RGD
InterPro
Ensembl		 PMID:34388369 GO_REF:0000002 GO_REF:0000003 GO_REF:0000024 GO_REF:0000107 NCBI chr18:59,320,932...59,337,272
Ensembl chr18:59,320,884...59,337,364 		JBrowse link
G St14 ST14 transmembrane serine protease matriptase enables ISO
IEA 		(PMID:20657595)
GO_REF:0000002 		RGD
InterPro		 PMID:20657595 GO_REF:0000002 NCBI chr 8:29,540,805...29,581,704
Ensembl chr 8:29,540,811...29,581,517 		JBrowse link
G Tmprss11a transmembrane serine protease 11A enables IEA GO_REF:0000104
GO_REF:0000002 		UniProt
InterPro		 GO_REF:0000002 GO_REF:0000104 NCBI chr14:21,624,881...21,665,284
Ensembl chr14:21,606,547...21,665,279 		JBrowse link
G Tmprss11b transmembrane serine protease 11B enables IEA GO_REF:0000104
GO_REF:0000002 		UniProt
InterPro		 GO_REF:0000002 GO_REF:0000104 NCBI chr14:21,383,936...21,407,283
Ensembl chr14:21,383,862...21,408,817 		JBrowse link
G Tmprss11c transmembrane protease, serine 11C enables ISO
IEA 		(PMID:18215125)
GO_REF:0000107
GO_REF:0000002
GO_REF:0000104 		RGD
Ensembl
InterPro
UniProt		 PMID:18215125 GO_REF:0000002 GO_REF:0000104 GO_REF:0000107 NCBI chr14:21,782,076...21,840,517
Ensembl chr14:21,782,124...21,837,793 		JBrowse link
G Tmprss11d transmembrane serine protease 11D enables IEA GO_REF:0000104
GO_REF:0000002 		UniProt
InterPro		 GO_REF:0000002 GO_REF:0000104 NCBI chr14:21,707,336...21,769,398
Ensembl chr14:21,707,336...21,769,396 		JBrowse link
G Tmprss11e transmembrane serine protease 11E enables IEA GO_REF:0000104
GO_REF:0000002 		UniProt
InterPro		 GO_REF:0000002 GO_REF:0000104 NCBI chr14:21,283,587...21,328,203
Ensembl chr14:21,282,823...21,327,184 		JBrowse link
G Tmprss11f transmembrane serine protease 11F enables IEA GO_REF:0000104
GO_REF:0000002 		UniProt
InterPro		 GO_REF:0000002 GO_REF:0000104 NCBI chr14:21,492,896...21,534,792
Ensembl chr14:21,429,418...21,534,809 		JBrowse link
G Tmprss11g transmembrane protease, serine 11G enables IEA GO_REF:0000104
GO_REF:0000002 		UniProt
InterPro		 GO_REF:0000002 GO_REF:0000104 NCBI chr14:21,546,087...21,587,258
Ensembl chr14:21,546,189...21,587,258 		JBrowse link
G Tmprss12 transmembrane serine protease 12 enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 7:131,433,158...131,445,806
Ensembl chr 7:131,433,484...131,445,791 		JBrowse link
G Tmprss13 transmembrane serine protease 13 enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 8:45,625,759...45,653,943
Ensembl chr 8:45,625,626...45,653,938 		JBrowse link
G Tmprss15 transmembrane serine protease 15 enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr11:17,677,741...17,802,255
Ensembl chr11:17,677,741...17,802,255 		JBrowse link
G Tmprss2 transmembrane serine protease 2 enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr11:36,934,306...36,973,779
Ensembl chr11:36,934,306...36,973,715 		JBrowse link
G Tmprss3 transmembrane serine protease 3 enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr20:9,254,102...9,273,808
Ensembl chr20:9,254,109...9,274,363 		JBrowse link
G Tmprss4 transmembrane serine protease 4 enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 8:45,475,819...45,508,409
Ensembl chr 8:45,476,053...45,508,409 		JBrowse link
G Tmprss5 transmembrane serine protease 5 enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 8:49,437,321...49,461,395
Ensembl chr 8:49,441,984...49,460,071 		JBrowse link
G Tmprss6 transmembrane serine protease 6 enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 7:109,991,008...110,021,626
Ensembl chr 7:109,985,931...110,021,624 		JBrowse link
G Tmprss7 transmembrane serine protease 7 enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr11:55,127,992...55,166,597
Ensembl chr11:55,128,998...55,164,882 		JBrowse link
G Tmprss9 transmembrane serine protease 9 enables IEA GO_REF:0000104
GO_REF:0000002 		UniProt
InterPro		 GO_REF:0000002 GO_REF:0000104 NCBI chr 7:8,810,321...8,831,177
Ensembl chr 7:8,810,320...8,831,177 		JBrowse link
G Tmprss9l1 transmembrane serine protease 9 like 1 enables IBA
IEA 		GO_REF:0000033
GO_REF:0000002 		GO_Central
InterPro		 GO_REF:0000002 GO_REF:0000033 NCBI chr14:41,360...54,088
Ensembl chr14:22,243...54,217 		JBrowse link
G Tpp1 tripeptidyl peptidase 1 enables IEA GO_REF:0000002
GO_REF:0000104 		InterPro
UniProt		 GO_REF:0000002 GO_REF:0000104 NCBI chr 1:160,097,984...160,104,108
Ensembl chr 1:160,096,833...160,104,129 		JBrowse link
G Tpp2 tripeptidyl peptidase 2 enables IEA GO_REF:0000002
GO_REF:0000104 		InterPro
UniProt		 GO_REF:0000002 GO_REF:0000104 NCBI chr 9:46,046,712...46,128,157
Ensembl chr 9:46,046,632...46,128,157 		JBrowse link
G Tpsab1 tryptase alpha/beta 1 enables IEA
IBA 		GO_REF:0000002
GO_REF:0000033
GO_REF:0000003 		InterPro
GO_Central
UniProt		 GO_REF:0000002 GO_REF:0000003 GO_REF:0000033 NCBI chr10:14,360,396...14,362,811
Ensembl chr10:14,360,396...14,362,811 		JBrowse link
G Tpsb2 tryptase beta 2 enables IEA
IBA 		GO_REF:0000002
GO_REF:0000033
GO_REF:0000003 		InterPro
GO_Central
UniProt		 GO_REF:0000002 GO_REF:0000003 GO_REF:0000033 NCBI chr10:14,381,779...14,383,571
Ensembl chr10:14,382,013...14,383,569 		JBrowse link
G Tpsg1 tryptase gamma 1 enables IBA
IEA 		GO_REF:0000033
GO_REF:0000002 		GO_Central
InterPro		 GO_REF:0000002 GO_REF:0000033 NCBI chr10:14,386,352...14,390,258
Ensembl chr10:14,386,352...14,390,258 		JBrowse link
G Try10 trypsin 10 enables IBA
IEA 		GO_REF:0000033
GO_REF:0000002 		GO_Central
InterPro		 GO_REF:0000002 GO_REF:0000033 NCBI chr 4:70,244,314...70,247,819
Ensembl chr 4:70,244,260...70,247,819 		JBrowse link
G Try5 trypsin 5 enables IBA
ISO
IEA 		GO_REF:0000033
(PMID:23814066)
GO_REF:0000002 		GO_Central
RGD
InterPro		 PMID:23814066 GO_REF:0000002 GO_REF:0000033 NCBI chr 4:70,213,760...70,217,034
Ensembl chr 4:70,213,756...70,217,051 		JBrowse link
G Tysnd1 trypsin like peroxisomal matrix peptidase 1 enables ISO
ISS
IBA
IEA 		(PMID:22002062)
GO_REF:0000024
GO_REF:0000033
(PMID:17255948)
GO_REF:0000107
GO_REF:0000002 		RGD
UniProt
GO_Central
Ensembl
InterPro		 PMID:17255948 PMID:22002062 GO_REF:0000002 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr20:29,637,942...29,646,492
Ensembl chr20:29,638,277...29,643,995 		JBrowse link
G Ubac2 UBA domain containing 2 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr15:98,960,139...99,107,795
Ensembl chr15:98,960,139...99,107,787 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 21102
    catalytic activity 6213
      hydrolase activity 2572
        peptidase activity 706
          endopeptidase activity 469
            serine-type endopeptidase activity 225
paths to the root