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ONTOLOGY REPORT - ANNOTATIONS

Term:dolichyl-phosphate-mannose-protein mannosyltransferase activity
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Accession:GO:0004169 term browser browse the term
Definition:Catalysis of the reaction: dolichyl phosphate D-mannose + protein = dolichyl phosphate + O-D-mannosylprotein.
Comment:Note that this activity has never been observed in green plants. However, N- and C-mannosylation may occur in these species; see figure 1 in PMID:21558543.
Synonyms:exact_synonym: dolichyl-phosphate-mannose-protein O-mannosyltransferase activity;   protein O-mannosyltransferase activity
 broad_synonym: O-glycoside mannosyltransferase
 related_synonym: dolichol phosphomannose-protein mannosyltransferase activity;   dolichyl-phosphate-D-mannose:protein O-D-mannosyltransferase activity;   protein O-D-mannosyltransferase activity
 xref: EC:2.4.1.109;   MetaCyc:2.4.1.109-RXN;   Reactome:R-HSA-5615556 "Defective POMT2 does not transfer Man from Dol-P-Man to DAG1";   Reactome:R-HSA-5615604 "Defective POMT1 does not transfer Man from Dol-P-Man to DAG1";   reactome:R-HSA-5615637 "POMT1:POMT2 transfers Man from Dol-P-Man to DAG1(30-653)"
 never_in_taxon: NCBITaxon:33090 ! Viridiplantae


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dolichyl-phosphate-mannose-protein mannosyltransferase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dpm1 dolichyl-phosphate mannosyltransferase subunit 1, catalytic enables ISO (PMID:9535917) RGD PMID:9535917 NCBI chr 3:156,919,979...156,939,522
Ensembl chr 3:156,919,979...156,939,536 		JBrowse link
G Pomt1 protein-O-mannosyltransferase 1 enables IEA GO_REF:0000003
GO_REF:0000104		 UniProt GO_REF:0000003 GO_REF:0000104 NCBI chr 3:15,520,717...15,538,579
Ensembl chr 3:15,520,481...15,538,581 		JBrowse link
G Pomt2 protein-O-mannosyltransferase 2 enables IEA GO_REF:0000003 UniProt GO_REF:0000003 NCBI chr 6:106,755,462...106,794,849
Ensembl chr 6:106,755,462...106,794,849 		JBrowse link
G Tmem260 transmembrane protein 260 enables ISO (PMID:37186866) RGD PMID:37186866 NCBI chr15:21,734,119...21,804,049
Ensembl chr15:21,734,151...21,806,801 		JBrowse link
G Tmtc1 transmembrane O-mannosyltransferase targeting cadherins 1 enables ISO (PMID:28973932) RGD PMID:28973932 NCBI chr 4:181,142,937...181,357,979
Ensembl chr 4:181,146,251...181,359,289 		JBrowse link
G Tmtc2 transmembrane O-mannosyltransferase targeting cadherins 2 enables ISO (PMID:28973932) RGD PMID:28973932 NCBI chr 7:40,392,377...40,806,685
Ensembl chr 7:40,394,220...40,807,298 		JBrowse link
G Tmtc3 transmembrane O-mannosyltransferase targeting cadherins 3 enables ISO (PMID:28973932) RGD PMID:28973932 NCBI chr 7:35,264,886...35,310,010
Ensembl chr 7:35,264,892...35,310,385 		JBrowse link
G Tmtc4 transmembrane O-mannosyltransferase targeting cadherins 4 enables ISO (PMID:28973932) RGD PMID:28973932 NCBI chr15:100,000,157...100,056,573
Ensembl chr15:100,000,152...100,056,543 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 20633
    catalytic activity 6032
      catalytic activity, acting on a protein 2509
        dolichyl-phosphate-mannose-protein mannosyltransferase activity 8
Path 2
Term Annotations click to browse term
  molecular_function 20633
    catalytic activity 6032
      transferase activity 2397
        glycosyltransferase activity 284
          hexosyltransferase activity 207
            mannosyltransferase activity 25
              dolichyl-phosphate-mannose-protein mannosyltransferase activity 8
paths to the root