Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)

ONTOLOGY REPORT - ANNOTATIONS

Term:cytochrome-c oxidase activity
go back to main search page
Accession:GO:0004129 term browser browse the term
Definition:Catalysis of the reaction: 4 ferrocytochrome c + O2 + 4 H+ = 4 ferricytochrome c + 2 H2O.
Comment:The reduction of O2 to water is accompanied by the extrusion of four protons from the intramitochondrial compartment.
Synonyms:narrow_synonym: aa3-type cytochrome c oxidase;   ba3-type cytochrome c oxidase;   caa3-type cytochrome c oxidase;   cbb3-type cytochrome c oxidase;   cytochrome a3 activity;   cytochrome aa3 activity;   indophenol oxidase;   indophenolase
 related_synonym: complex IV (mitochondrial electron transport) activity;   cytochrome oxidase activity;   warburg's respiratory enzyme activity
 xref: EC:7.1.1.9;   MetaCyc:CYTOCHROME-C-OXIDASE-RXN;   RHEA:11436;   reactome:R-HSA-163214 "Electron transfer from reduced cytochrome c to molecular oxygen"

GViewer not supported for the selected species.

show annotations for term's descendants           Sort by:
cytochrome-c oxidase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G COX1 enables IEA UniProt
RHEA
InterPro
Ensembl
TreeGrafter		 GO_REF:0000002 GO_REF:0000003 GO_REF:0000107 GO_REF:0000116 GO_REF:0000118 NCBI chr MT:5,347...6,888 JBrowse link
G COX2 enables IEA Ensembl
UniProt
InterPro
TreeGrafter		 GO_REF:0000002 GO_REF:0000003 GO_REF:0000107 GO_REF:0000118 NCBI chr MT:7,032...7,715 JBrowse link
G COX3 enables IEA UniProt
InterPro
TreeGrafter		 GO_REF:0000002 GO_REF:0000003 GO_REF:0000118 NCBI chr MT:8,627...9,410 JBrowse link
G COX4I2 cytochrome c oxidase subunit 4I2 enables IEA Ensembl GO_REF:0000107 Ensembl chrNW_004936485:18,631,322...18,644,593 JBrowse link
G LOC101965810 cytochrome c oxidase subunit 7A1, mitochondrial contributes_to ISO (PMID:22119795), (PMID:22869013) UniProt PMID:22119795 PMID:22869013 NCBI chrNW_004936922:162,282...163,864
Ensembl chrNW_004936922:162,286...163,839 		JBrowse link
G LOC101971648 cytochrome c oxidase subunit 5A, mitochondrial ISO RGD PMID:7601105 RGD:727762 NCBI chrNW_004936471:33,874,638...33,887,377
Ensembl chrNW_004936471:33,872,842...33,887,400 		JBrowse link
G LOC101971854 surfeit locus protein 1 enables IEA Ensembl GO_REF:0000107 NCBI chrNW_004936669:3,527,741...3,532,087
Ensembl chrNW_004936669:3,527,761...3,534,586 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 17135
    electron transfer activity 52
      cytochrome-c oxidase activity 7
Path 2
Term Annotations click to browse term
  molecular_function 17135
    transporter activity 1151
      transmembrane transporter activity 1051
        active transmembrane transporter activity 388
          primary active transmembrane transporter activity 136
            oxidoreduction-driven active transmembrane transporter activity 31
              cytochrome-c oxidase activity 7
paths to the root