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ONTOLOGY REPORT - ANNOTATIONS

Term:cytochrome-b5 reductase activity, acting on NAD(P)H
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Accession:GO:0004128 term browser browse the term
Definition:Catalysis of the reaction: NAD(P)H + H+ + 2 ferricytochrome b(5) = NAD(P)+ + 2 ferrocytochrome b(5).
Synonyms:related_synonym: NADH 5alpha-reductase activity;   NADH-cytochrome b5 reductase activity;   NADH-ferricytochrome b5 oxidoreductase activity;   cytochrome b5 reductase activity;   dihydronicotinamide adenine dinucleotide-cytochrome b5 reductase activity;   reduced nicotinamide adeninedinucleotide-cytochrome b5 reductase activity
 xref: EC:1.6.2.2;   MetaCyc:CYTOCHROME-B5-REDUCTASE-RXN;   RHEA:46680;   reactome:R-HSA-198824 "CYB5R3:FAD reduces CYB5A:ferriheme to CYB5A:heme";   reactome:R-HSA-6806831 "CYB5Rs reduce MetHb to HbA"


show annotations for term's descendants           Sort by:
cytochrome-b5 reductase activity, acting on NAD(P)H term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyb5r1 cytochrome b5 reductase 1 enables IEA GO_REF:0000003
GO_REF:0000116
GO_REF:0000117		 UniProt
RHEA		 GO_REF:0000003 GO_REF:0000116 GO_REF:0000117 NCBI chr13:45,849,017...45,855,458
Ensembl chr13:45,849,091...45,855,458 		JBrowse link
G Cyb5r2 cytochrome b5 reductase 2 enables IEA
ISO		 GO_REF:0000003
(PMID:10611283)
GO_REF:0000117
GO_REF:0000116		 UniProt
RGD
RHEA		 PMID:10611283 GO_REF:0000003 GO_REF:0000116 GO_REF:0000117 NCBI chr 1:161,655,862...161,664,359
Ensembl chr 1:161,655,864...161,664,097 		JBrowse link
G Cyb5r3 cytochrome b5 reductase 3 enables TAS
ISO
IDA
IEA		 (PMID:10807796), (PMID:1400360), (PMID:15953014), (PMID:1898726), (PMID:2019583), (PMID:8119939), (PMID:9639531)
(PMID:16814740)
(PMID:10082957), (PMID:11574067), (PMID:3967486)
PMID:11695905
PMID:8812833
PMID:8978818
GO_REF:0000117		 RGD
UniProt		 PMID:1400360 PMID:1898726 PMID:2019583 PMID:3967486 PMID:8119939 More... GO_REF:0000117, RGD:728516, RGD:153298935, RGD:153298951, RGD:153298962 NCBI chr 7:114,306,686...114,324,247
Ensembl chr 7:114,306,685...114,324,298 		JBrowse link
G Cyb5r4 cytochrome b5 reductase 4 enables ISO
IEA
IBA		 (PMID:10611283)
GO_REF:0000003
GO_REF:0000033
GO_REF:0000118
(PMID:15131110)		 RGD
UniProt
GO_Central
TreeGrafter		 PMID:10611283 PMID:15131110 GO_REF:0000003 GO_REF:0000033 GO_REF:0000118 NCBI chr 8:87,975,596...88,048,356
Ensembl chr 8:87,981,116...88,045,832 		JBrowse link
G Cyb5rl cytochrome b5 reductase-like enables IEA GO_REF:0000003
GO_REF:0000118		 UniProt
TreeGrafter		 GO_REF:0000003 GO_REF:0000118 NCBI chr 5:121,846,223...121,868,287
Ensembl chr 5:121,847,952...121,868,745 		JBrowse link
G Por cytochrome p450 oxidoreductase IDA RGD PMID:16055078 RGD:4889840 NCBI chr12:20,951,058...20,999,198
Ensembl chr12:20,951,058...20,999,245 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 20890
    catalytic activity 6118
      oxidoreductase activity 872
        oxidoreductase activity, acting on NAD(P)H 65
          oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor 11
            cytochrome-b5 reductase activity, acting on NAD(P)H 6
              cytochrome-b5 reductase activity, acting on NADH 0
              cytochrome-b5 reductase activity, acting on NADPH 0
paths to the root