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ONTOLOGY REPORT - ANNOTATIONS

Term:cytidine deaminase activity
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Accession:GO:0004126 term browser browse the term
Definition:Catalysis of the reaction: cytidine + H2O = uridine + NH3.
Synonyms:related_synonym: cytidine aminohydrolase activity;   cytosine nucleoside deaminase activity
 xref: EC:3.5.4.5;   MetaCyc:CYTIDEAM2-RXN;   RHEA:16069;   Reactome:R-HSA-9817513 "AICDA deaminates cytidine in chromatin containing histone H3.3 and 5-methylcytidine";   reactome:R-HSA-73608 "(deoxy)cytidine + H2O => (deoxy)uridine + NH4+ (CDA)";   reactome:R-HSA-83677 "C4 deamination of cytidine"


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cytidine deaminase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aicda activation-induced cytidine deaminase enables ISO
IBA		 (PMID:18722174)
GO_REF:0000033
(MGI:2656023|PMID:12692563), (MGI:6500774|PMID:24279473), (PMID:10373455)		 RGD
GO_Central		 PMID:10373455 PMID:12692563 PMID:18722174 PMID:24279473 GO_REF:0000033 MGI:2656023 MGI:6500774 NCBI chr 4:155,774,132...155,783,972
Ensembl chr 4:155,774,132...155,783,972 		JBrowse link
G Apobec1 apolipoprotein B mRNA editing enzyme catalytic subunit 1 enables IDA
NAS
IEA
IBA		 PMID:15448152
PMID:10781591
GO_REF:0000118
GO_REF:0000033		 TreeGrafter
GO_Central
RGD		 PMID:8511591 PMID:15448152 PMID:10781591 GO_REF:0000033 GO_REF:0000118, RGD:634661, RGD:8554599, RGD:8553657 NCBI chr 4:155,800,030...155,828,515
Ensembl chr 4:155,800,887...155,827,390 		JBrowse link
G Apobec2 apolipoprotein B mRNA editing enzyme catalytic subunit 2 enables ISO
IBA		 (PMID:10403781)
GO_REF:0000033		 RGD
GO_Central		 PMID:10403781 GO_REF:0000033 NCBI chr 9:12,564,955...12,578,461
Ensembl chr 9:12,564,920...12,578,458 		JBrowse link
G Apobec3 apolipoprotein B mRNA editing enzyme catalytic subunit 3 enables ISO
IEA
IBA		 (PMID:16571802)
GO_REF:0000118
GO_REF:0000033		 RGD
TreeGrafter
GO_Central		 PMID:16571802 GO_REF:0000033 GO_REF:0000118 NCBI chr 7:111,433,789...111,453,032
Ensembl chr 7:111,433,764...111,452,922 		JBrowse link
G Cda cytidine deaminase enables IDA
ISO
IBA		 (PMID:7923172), (PMID:9596658)
GO_REF:0000033
(PMID:16784234), (PMID:5651639)		 RGD
GO_Central		 PMID:5651639 PMID:7923172 PMID:9596658 PMID:16784234 PMID:675715 GO_REF:0000033, RGD:2316616 NCBI chr 5:150,556,615...150,583,231
Ensembl chr 5:150,556,615...150,583,231 		JBrowse link
G Cdadc1 cytidine and dCMP deaminase domain containing 1 enables ISO (PMID:26945630) RGD PMID:26945630 NCBI chr15:33,726,590...33,755,611
Ensembl chr15:33,723,435...33,755,576 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 20890
    catalytic activity 6118
      hydrolase activity 2630
        hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 135
          deaminase activity 26
            cytidine deaminase activity 6
paths to the root