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ONTOLOGY REPORT - ANNOTATIONS


Term:branched-chain-amino-acid transaminase activity
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Accession:GO:0004084 term browser browse the term
Definition:Catalysis of the reaction: a branched-chain amino acid + 2-oxoglutarate = L-glutamate + a 2-oxocarboxylate derived from the branched-chain amino acid.
Synonyms:exact_synonym: L-branched chain amino acid aminotransferase activity;   branched-chain amino acid aminotransferase activity;   branched-chain amino acid-glutamate transaminase activity;   branched-chain aminotransferase activity;   branched-chain-amino-acid:2-oxoglutarate aminotransferase activity
 related_synonym: transaminase B activity
 xref: EC:2.6.1.42;   reactome:R-HSA-508179 "a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT2]";   reactome:R-HSA-508189 "a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT1]";   reactome:R-HSA-70723 "leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT1]";   reactome:R-HSA-70724 "leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT2]"


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branched-chain-amino-acid transaminase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bcat1 branched chain amino acid transaminase 1 JBrowse link 4 179,259,305 179,340,021 RGD:631308
RGD:13792537
RGD:1624291
RGD:1599451
G Bcat2 branched chain amino acid transaminase 2 JBrowse link 1 101,553,900 101,572,103 RGD:67954
RGD:13792537
RGD:1624291
RGD:1582175
L-isoleucine transaminase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bcat1 branched chain amino acid transaminase 1 JBrowse link 4 179,259,305 179,340,021 RGD:1600115
G Bcat2 branched chain amino acid transaminase 2 JBrowse link 1 101,553,900 101,572,103 RGD:1600115
L-leucine transaminase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bcat1 branched chain amino acid transaminase 1 JBrowse link 4 179,259,305 179,340,021 RGD:1600115
G Bcat2 branched chain amino acid transaminase 2 JBrowse link 1 101,553,900 101,572,103 RGD:1600115
L-valine transaminase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bcat1 branched chain amino acid transaminase 1 JBrowse link 4 179,259,305 179,340,021 RGD:1600115
G Bcat2 branched chain amino acid transaminase 2 JBrowse link 1 101,553,900 101,572,103 RGD:1600115

Term paths to the root
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Term Annotations click to browse term
  molecular_function 19526
    catalytic activity 6039
      transferase activity 2385
        transferase activity, transferring nitrogenous groups 29
          transaminase activity 26
            branched-chain-amino-acid transaminase activity 2
              L-isoleucine transaminase activity 2
              L-leucine transaminase activity 2
              L-valine transaminase activity 2
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.