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ONTOLOGY REPORT - ANNOTATIONS
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Term:
biotin--[biotin carboxyl-carrier protein] ligase activity
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Accession:
GO:0004077
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Definition:
Catalysis of the reaction: ATP + biotin + L-lysyl-[protein] = AMP + diphosphate + H+ + N(6)-biotinyl-L-lysyl-[protein].
Synonyms:
broad_synonym:
biotin-acetyl-CoA carboxylase synthetase
related_synonym:
HCS; acetyl CoA holocarboxylase synthetase activity; acetyl coenzyme A holocarboxylase synthetase activity; acetyl-CoA carboxylase biotin holoenzyme synthetase activity; biotin holoenzyme synthetase activity; biotin--[acetyl-CoA carboxylase] synthetase activity; biotin--protein ligase activity; biotin-acetyl coenzyme A carboxylase synthetase activity; biotin-acetyl-CoA-carboxylase ligase activity; biotin:apo-acetyl-CoA:carbon-dioxide ligase (ADP-forming) ligase (AMP-forming); biotin:apocarboxylase ligase activity
xref:
EC:6.3.4.15; MetaCyc:BIOTINLIG-RXN; RHEA:11756
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Genes (1)
biotin--[biotin carboxyl-carrier protein] ligase activity
Symbol
Object Name
Qualifiers
Evidence
Notes
Source
PubMed Reference(s)
RGD Reference(s)
Position
G
Hlcs
holocarboxylase synthetase
enables
IDA
IBA
ISO
GO_REF:0000033
(PMID:14613969), (PMID:18429047), (PMID:7842009), (PMID:9630604)
MGI:6446223 (PMID:35385533)
GO_Central
RGD
PMID:7842009
PMID:9630604
PMID:14613969
PMID:18429047
PMID:35385533
PMID:7849632
More...
GO_REF:0000033,
RGD:2313679
NCBI chr11:33,455,806...33,635,197
Ensembl chr11:33,455,809...33,624,222
Term paths to the root
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one longest
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Path 1
Term
Annotations
molecular_function
20634
catalytic activity
6032
catalytic activity, acting on a protein
2509
biotin--[biotin carboxyl-carrier protein] ligase activity
1
Path 2
Term
Annotations
molecular_function
20634
catalytic activity
6032
ligase activity
178
ligase activity, forming carbon-nitrogen bonds
51
biotin--[biotin carboxyl-carrier protein] ligase activity
1