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ONTOLOGY REPORT - ANNOTATIONS

Term:aromatic-L-amino-acid decarboxylase activity
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Accession:GO:0004058 term browser browse the term
Definition:Catalysis of the reaction: L-amino acid + H+ = R-H + CO2.
Synonyms:narrow_synonym: 5-hydroxytryptophan decarboxylase activity;   DOPA decarboxylase activity;   L-DOPA decarboxylase activity;   aromatic-L-amino-acid carboxy-lyase (tryptamine-forming);   hydroxytryptophan decarboxylase activity;   tryptophan decarboxylase activity
 related_synonym: aromatic amino acid decarboxylase activity;   aromatic-L-amino-acid carboxy-lyase activity
 alt_id: GO:0016400
 xref: EC:4.1.1.28;   MetaCyc:AROMATIC-L-AMINO-ACID-DECARBOXYLASE-RXN;   reactome:R-HSA-209859 "Decarboxylation of 5-hydroxytryptophan forms serotonin";   reactome:R-HSA-209924 "Dopa is decarboxylated to dopamine"


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aromatic-L-amino-acid decarboxylase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DDC dopa decarboxylase enables ISO
IEA
IBA		 RGD
TreeGrafter
GO_Central
Ensembl
UniProt		 PMID:3379830 PMID:10569946 PMID:12047348 PMID:12703659 GO_REF:0000003 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 RGD:4139893 RGD:4139897 RGD:4139900 RGD:727571 NCBI chr 9:136,496,364...136,571,220
Ensembl chr 9:136,496,365...136,571,212 		JBrowse link
G FIGNL1 fidgetin like 1 enables IEA TreeGrafter GO_REF:0000118 NCBI chr 9:136,484,217...136,488,262
Ensembl chr 9:136,484,216...136,488,250 		JBrowse link
5-hydroxy-L-tryptophan decarboxylase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DDC dopa decarboxylase enables IEA RHEA
Ensembl		 GO_REF:0000107 GO_REF:0000116 NCBI chr 9:136,496,364...136,571,220
Ensembl chr 9:136,496,365...136,571,212 		JBrowse link
L-dopa decarboxylase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DDC dopa decarboxylase enables IEA Ensembl
RHEA		 GO_REF:0000107 GO_REF:0000116 NCBI chr 9:136,496,364...136,571,220
Ensembl chr 9:136,496,365...136,571,212 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 18689
    catalytic activity 5662
      lyase activity 202
        carbon-carbon lyase activity 54
          carboxy-lyase activity 35
            aromatic-L-amino-acid decarboxylase activity 2
              5-hydroxy-L-tryptophan decarboxylase activity 1
              L-dopa decarboxylase activity 1
              L-tryptophan decarboxylase activity 0
paths to the root