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ONTOLOGY REPORT - ANNOTATIONS


Term:alditol:NADP+ 1-oxidoreductase activity
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Accession:GO:0004032 term browser browse the term
Definition:Catalysis of the reaction: an alditol + NADP+ = an aldose + NADPH + H+.
Synonyms:exact_synonym: aldehyde reductase activity;   aldose reductase activity
 related_synonym: polyol dehydrogenase (NADP(+)) activity
 xref: EC:1.1.1.21;   KEGG_REACTION:R02820;   MetaCyc:ALDEHYDE-REDUCTASE-RXN;   reactome:R-HSA-196060 "Reduction of isocaproaldehyde to 4-methylpentan-1-ol";   reactome:R-HSA-5652172 "AKR1B1 reduces Glc to D-sorbitol"


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alditol:NADP+ 1-oxidoreductase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Adh4 alcohol dehydrogenase 4 (class II), pi polypeptide JBrowse link 3 138,415,456 138,432,683 RGD:2290270
G Akr1a1 aldo-keto reductase family 1, member A1 (aldehyde reductase) JBrowse link 4 116,636,510 116,651,674 RGD:2290270
G Akr1b10 aldo-keto reductase family 1, member B10 (aldose reductase) JBrowse link 6 34,384,247 34,396,949 RGD:2290270
G Akr1b3 aldo-keto reductase family 1, member B3 (aldose reductase) JBrowse link 6 34,303,930 34,317,489 RGD:2290270
G Akr1b7 aldo-keto reductase family 1, member B7 JBrowse link 6 34,412,362 34,423,137 RGD:2290270
G Akr1b8 aldo-keto reductase family 1, member B8 JBrowse link 6 34,354,146 34,368,461 RGD:2290270
G Akr1c12 aldo-keto reductase family 1, member C12 JBrowse link 13 4,268,172 4,279,399 RGD:2290270
G Akr1c13 aldo-keto reductase family 1, member C13 JBrowse link 13 4,191,168 4,205,604 RGD:2290270
G Akr1c14 aldo-keto reductase family 1, member C14 JBrowse link 13 4,048,991 4,090,560 RGD:2290270
G Akr1c18 aldo-keto reductase family 1, member C18 JBrowse link 13 4,132,615 4,150,646 RGD:2290270
G Akr1c19 aldo-keto reductase family 1, member C19 JBrowse link 13 4,233,503 4,248,361 RGD:2290270
G Akr1c20 aldo-keto reductase family 1, member C20 JBrowse link 13 4,486,856 4,523,354 RGD:2290270
G Akr1c21 aldo-keto reductase family 1, member C21 JBrowse link 13 4,574,075 4,586,543 RGD:2290270
G Akr1c6 aldo-keto reductase family 1, member C6 JBrowse link 13 4,434,311 4,457,530 RGD:2290270
G Akr1cl aldo-keto reductase family 1, member C-like JBrowse link 1 65,013,078 65,032,759 RGD:2290270
G Akr1d1 aldo-keto reductase family 1, member D1 JBrowse link 6 37,529,978 37,574,921 RGD:2290270
G Akr1e1 aldo-keto reductase family 1, member E1 JBrowse link 13 4,591,123 4,609,164 RGD:2290270
G Akr7a5 aldo-keto reductase family 7, member A5 (aflatoxin aldehyde reductase) JBrowse link 4 139,310,720 139,318,786 RGD:2290270
G Aldr2 aldehyde reductase 2 RGD:2290270
G Aldr3 aldehyde reductase 3 RGD:2290270
G Aldr4 aldehyde reductase 4 RGD:2290270

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  molecular_function 22376
    catalytic activity 5700
      oxidoreductase activity 806
        oxidoreductase activity, acting on CH-OH group of donors 153
          oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 146
            aldo-keto reductase (NADP) activity 34
              alcohol dehydrogenase (NADP+) activity 30
                alditol:NADP+ 1-oxidoreductase activity 21
                  D-xylose:NADP reductase activity 0
                  L-arabinose:NADP reductase activity 0
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.