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ONTOLOGY REPORT - ANNOTATIONS


Term:alcohol dehydrogenase (NAD+) activity
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Accession:GO:0004022 term browser browse the term
Definition:Catalysis of the reaction: an alcohol + NAD+ = an aldehyde or ketone + NADH + H+.
Synonyms:exact_synonym: aldo-keto reductase (NAD) activity
 narrow_synonym: aldehyde dehydrogenase (NAD) activity;   aliphatic alcohol dehydrogenase;   ethanol dehydrogenase;   yeast alcohol dehydrogenase
 broad_synonym: alcohol dehydrogenase activity;   primary alcohol dehydrogenase
 related_synonym: ADH;   NAD-dependent alcohol dehydrogenase;   NAD-specific aromatic alcohol dehydrogenase;   NADH-alcohol dehydrogenase;   NADH-aldehyde dehydrogenase;   alcohol:NAD+ oxidoreductase
 xref: EC:1.1.1.1;   MetaCyc:ALCOHOL-DEHYDROG-GENERIC-RXN;   RHEA:10740;   UM-BBD_enzymeID:e0023;   reactome:R-HSA-2162078 "abacavir + 2 NAD+ => abacavir 5'-carboxylate + 2 NADH + 2 H+"



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alcohol dehydrogenase (NAD+) activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adh1 alcohol dehydrogenase 1C (class I), gamma polypeptide enables TAS
IEA
ISO
IDA
GO_REF:0000107
(MGI:54726|PMID:518534), (MGI:55087|PMID:7026729), (MGI:55389|PMID:6816803), (MGI:55875|PMID:6370228), (MGI:56327|PMID:3996732)
(PMID:6391957)
Ensembl
RGD
PMID:518534 PMID:3996732 PMID:6370228 PMID:6391957 PMID:6816803 More... GO_REF:0000107 MGI:54726 MGI:55087 MGI:55389 MGI:55875 MGI:56327, RGD:631178, RGD:1642948, RGD:1642949 NCBI chr 2:226,797,303...226,808,892
Ensembl chr 2:226,797,303...226,808,892
JBrowse link
G Adh4 alcohol dehydrogenase 4 (class II), pi polypeptide enables IDA
ISO
IEA
(MGI:54726|PMID:518534)
GO_REF:0000003
(PMID:16787387), (PMID:3466164)
RGD
UniProt
PMID:518534 PMID:3466164 PMID:16787387 PMID:2774584 GO_REF:0000003 MGI:54726, RGD:1358222 NCBI chr 2:226,948,717...226,966,747
Ensembl chr 2:226,947,466...226,987,591
JBrowse link
G Adh5 alcohol dehydrogenase 5 (class III), chi polypeptide enables IDA
ISO
IEA
(MGI:56327|PMID:3996732)
GO_REF:0000003
RGD
UniProt
PMID:3996732 PMID:18207224 GO_REF:0000003 MGI:56327, RGD:5129089 NCBI chr 2:226,975,184...226,987,591
Ensembl chr 2:226,947,466...226,987,591
JBrowse link
G Adh6 alcohol dehydrogenase 6 (class V) enables ISO (PMID:1755855) RGD PMID:1755855 NCBI chr 2:226,903,208...226,934,564
Ensembl chr 2:226,903,250...226,934,534
JBrowse link
G Adh7 alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide enables TAS
IEA
ISO
IDA
GO_REF:0000107
(MGI:54726|PMID:518534), (MGI:55087|PMID:7026729), (MGI:55903|PMID:6372555)
Ensembl
RGD
PMID:518534 PMID:6372555 PMID:7026729 PMID:12631290 PMID:10829036 GO_REF:0000107 MGI:52973 MGI:54726 MGI:55087 MGI:55903, RGD:631178, RGD:631904 NCBI chr 2:226,748,724...226,763,183
Ensembl chr 2:226,741,788...226,763,182
JBrowse link
G Adhfe1 alcohol dehydrogenase, iron containing, 1 enables IBA
IEA
PMID:21873635
GO_REF:0000002
InterPro PMID:21873635 GO_REF:0000002, RGD:13792537 NCBI chr 5:9,705,966...9,732,580
Ensembl chr 5:9,705,970...9,732,517
JBrowse link
G Dhrs9 dehydrogenase/reductase 9 enables ISS
ISO
GO_REF:0000024
(PMID:11304534)
UniProt
RGD
PMID:11304534 GO_REF:0000024 NCBI chr 3:54,147,834...54,170,052
Ensembl chr 3:54,147,803...54,220,241
JBrowse link
alcohol dehydrogenase activity, zinc-dependent term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adh1 alcohol dehydrogenase 1C (class I), gamma polypeptide enables IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 2:226,797,303...226,808,892
Ensembl chr 2:226,797,303...226,808,892
JBrowse link
G Adh4 alcohol dehydrogenase 4 (class II), pi polypeptide enables ISO
IBA
(PMID:10407146)
(MGI:1346361|PMID:10514444)
PMID:21873635
RGD PMID:10407146 PMID:10514444 PMID:21873635 MGI:1346361, RGD:13792537 NCBI chr 2:226,948,717...226,966,747
Ensembl chr 2:226,947,466...226,987,591
JBrowse link
G Adh5 alcohol dehydrogenase 5 (class III), chi polypeptide enables IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 2:226,975,184...226,987,591
Ensembl chr 2:226,947,466...226,987,591
JBrowse link
G Adh6 alcohol dehydrogenase 6 (class V) enables IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 2:226,903,208...226,934,564
Ensembl chr 2:226,903,250...226,934,534
JBrowse link
G Adh6a alcohol dehydrogenase 6A (class V) enables IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 2:226,823,775...226,846,005
Ensembl chr 2:226,823,730...226,846,003
JBrowse link
G Adh7 alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide enables IBA
ISO
PMID:21873635
(PMID:7876099)
RGD PMID:7876099 PMID:21873635 RGD:13792537 NCBI chr 2:226,748,724...226,763,183
Ensembl chr 2:226,741,788...226,763,182
JBrowse link

Term paths to the root
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Term Annotations click to browse term
  molecular_function 20704
    catalytic activity 6091
      oxidoreductase activity 862
        oxidoreductase activity, acting on CH-OH group of donors 165
          oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 156
            alcohol dehydrogenase [NAD(P)+] activity 9
              alcohol dehydrogenase (NAD+) activity 8
                3-methylbutanol:NAD oxidoreductase activity 0
                alcohol dehydrogenase activity, iron-dependent 0
                alcohol dehydrogenase activity, metal ion-independent 0
                alcohol dehydrogenase activity, zinc-dependent 6
                butanol dehydrogenase activity 0
                inositol 2-dehydrogenase activity 0
                xanthoxin dehydrogenase activity 0
paths to the root