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ONTOLOGY REPORT - ANNOTATIONS

Term:IMP dehydrogenase activity
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Accession:GO:0003938 term browser browse the term
Definition:Catalysis of the reaction: inosine 5'-phosphate + NAD+ + H2O = xanthosine 5'-phosphate + NADH + H+.
Synonyms:related_synonym: IMP oxidoreductase activity;   IMP:NAD+ oxidoreductase activity;   inosinate dehydrogenase activity;   inosine 5'-monophosphate dehydrogenase activity;   inosine monophosphate dehydrogenase activity;   inosine monophosphate oxidoreductase activity;   inosine-5'-phosphate dehydrogenase activity;   inosinic acid dehydrogenase activity
 xref: EC:1.1.1.205;   MetaCyc:IMP-DEHYDROG-RXN;   RHEA:11708;   Reactome:R-HSA-9748945 "IMPDH tetramers dehydrogenate 6TIMP to 6TXMP";   reactome:R-HSA-73794 "IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2]"


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IMP dehydrogenase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Impdh1 inosine monophosphate dehydrogenase 1 enables IBA
IDA		 (PMID:12944494), (PMID:31838626) GO_Central
MGI		 PMID:12944494 PMID:31838626 GO_REF:0000033 NCBI chr 6:29,200,435...29,216,363
Ensembl chr 6:29,200,433...29,216,363 		JBrowse link
G Impdh2 inosine monophosphate dehydrogenase 2 enables ISO
IMP
IDA
IBA		 (PMID:12944494)
(PMID:12944494), (PMID:1671845)		 MGI
RGD
GO_Central		 PMID:1671845 PMID:2897864 PMID:12944494 GO_REF:0000033 GO_REF:0000096 GO_REF:0000119 MGI:4417868 MGI:4834177 RGD:5147398 NCBI chr 9:108,437,635...108,442,776
Ensembl chr 9:108,437,485...108,442,783 		JBrowse link
G Impdh2-ps inosine monophosphate dehydrogenase 2, pseudogene enables ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 8:100,757,119...100,758,788
Ensembl chr 8:100,757,190...100,758,734 		JBrowse link
Term paths to the root
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Term Annotations click to browse term
  molecular_function 28831
    catalytic activity 5714
      oxidoreductase activity 786
        oxidoreductase activity, acting on CH-OH group of donors 161
          oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 151
            IMP dehydrogenase activity 3
paths to the root