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ONTOLOGY REPORT - ANNOTATIONS


Term:GTPase activity
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Accession:GO:0003924 term browser browse the term
Definition:Catalysis of the reaction: GTP + H2O = GDP + phosphate.
Synonyms:narrow_synonym: ARF small monomeric GTPase activity;   RHEB small monomeric GTPase activity;   Rab small monomeric GTPase activity;   Ran small monomeric GTPase activity;   Ras small monomeric GTPase activity;   Rho small monomeric GTPase activity;   Sar small monomeric GTPase activity;   dynamin GTPase activity;   heterotrimeric G-protein GTPase activity;   protein-synthesizing GTPase activity;   protein-synthesizing GTPase activity, elongation;   protein-synthesizing GTPase activity, initiation;   protein-synthesizing GTPase activity, termination;   signal-recognition-particle GTPase activity;   small monomeric GTPase activity;   tubulin GTPase activity
 broad_synonym: hydrolase activity, acting on acid anhydrides, acting on GTP, involved in cellular and subcellular movement
 related_synonym: GTPase activity, coupled;   heterotrimeric G-protein GTPase, alpha-subunit;   heterotrimeric G-protein GTPase, beta-subunit;   heterotrimeric G-protein GTPase, gamma-subunit
 alt_id: GO:0061745
 xref: RHEA:19669;   reactome:R-HSA-1445143 "RAB8A,10,13,14 hydrolyze GTP";   reactome:R-HSA-1458485 "RALA hydrolyzes GTP";   reactome:R-HSA-156923 "Hydrolysis of eEF1A:GTP";   reactome:R-HSA-164381 "G alpha (s) auto-inactivates by hydrolysing GTP to GDP";   reactome:R-HSA-165055 "Hydrolysis of Ran:GTP to Ran:GDP";   reactome:R-HSA-167415 "G-protein alpha subunit is inactivated";   reactome:R-HSA-170666 "Adenylate cyclase increases the GTPase activity of G alpha-olf";   reactome:R-HSA-170685 "Adenylaye cyclase increases the GTPase activity of G alpha-olf";   reactome:R-HSA-170686 "Adenylate cyclase increases the GTPase activity of Gi alpha";   reactome:R-HSA-177501 "Endocytosis (internalization) of clathrin-coated vesicle";   reactome:R-HSA-203973 "Vesicle budding";   reactome:R-HSA-2130641 "Translocation of TGN-lysosome vesicle to lysosome";   reactome:R-HSA-2130725 "Internalization of MHC II:Ii clathrin coated vesicle";   reactome:R-HSA-2584246 "GNAT1-GTP hydrolyses its bound GTP to GDP";   reactome:R-HSA-380979 "RHEB in mTORC1:RHEB:GTP hydrolyses GTP";   reactome:R-HSA-392133 "G alpha (z) auto-inactivates by hydrolysing GTP to GDP";   reactome:R-HSA-392212 "G alpha (i) auto-inactivates by hydrolysing GTP to GDP";   reactome:R-HSA-418574 "G alpha (12/13) auto-inactivates by hydrolysing GTP to GDP";   reactome:R-HSA-418582 "G alpha (q) auto-inactivates by hydrolysing GTP to GDP";   reactome:R-HSA-421835 "trans-Golgi Network Vesicle Scission";   reactome:R-HSA-428941 "P2Y purinoceptor 1 activates MAP kinase p38 alpha";   reactome:R-HSA-432707 "trans-Golgi Network Lysosomal Vesicle Scission";   reactome:R-HSA-5333615 "80S:Met-tRNAi:mRNA:SECISBP2:Sec-tRNA(Sec):EEFSEC:GTP is hydrolysed to 80S:Met-tRNAi:mRNA:SECISBP2:Sec and EEFSEC:GDP by EEFSEC";   reactome:R-HSA-5389839 "39S subunit binds 28S subunit:mRNA:fMet-tRNA";   reactome:R-HSA-5389842 "TUFM hydrolyzes GTP and TUFM:GDP dissociates from 55S ribosome";   reactome:R-HSA-5419273 "Hydrolysis of GTP and dissociation of 28S and 39S subunits";   reactome:R-HSA-5419279 "Translocation of peptidyl-tRNA from A-site to P-site (and translocation of 55S ribosome by 3 bases along mRNA)";   reactome:R-HSA-555065 "Formation of clathrin coated vesicle";   reactome:R-HSA-5623513 "ASAP1 stimulates GTPase activity of ARF4";   reactome:R-HSA-5638006 "ARL3 hydrolyzes GTP";   reactome:R-HSA-5658231 "RAS GAPs stimulate RAS GTPase activity";   reactome:R-HSA-5665809 "SRGAP2 stimulates RAC1 GTP-ase activity and ends FMNL1-mediated elongation of actin filaments";   reactome:R-HSA-5672017 "Rheb in the mTORC1 complex hydrolyses GTP";   reactome:R-HSA-5694527 "Loss of SAR1B GTPase";   reactome:R-HSA-6807877 "ARFGAPs stimulate ARF GTPase activity";   reactome:R-HSA-6814833 "TBC1D20 stimulates GTPase activity of RAB1, resulting in hydrolysis of GTP";   reactome:R-HSA-8847534 "RAB43 hydrolyses GTP";   reactome:R-HSA-8847883 "CYTH proteins stimulate ARF1 GTPase activity";   reactome:R-HSA-8849082 "ARHGAP35 stimulates RHOA GTPase activity";   reactome:R-HSA-8854173 "TBC RabGAPs accelerate GTP hydrolysis by RAB35";   reactome:R-HSA-8854255 "TBC1D2A accelerates GTP hydrolysis by RAB7";   reactome:R-HSA-8854329 "TBC1D15 accelerates GTP hydrolysis by RAB7";   reactome:R-HSA-8854604 "TBC1D16 accelerates GTP hydrolysis by RAB4A";   reactome:R-HSA-8854612 "TBC1D25 accelerates GTP hydrolysis by RAB33B";   reactome:R-HSA-8868661 "Dynamin-mediated GTP hydrolysis promotes vesicle scission";   reactome:R-HSA-8981353 "RASA1 stimulates RAS GTPase activity";   reactome:R-HSA-8982020 "G alpha (i)i1/i2/i3 in G (i):RGS complex is inactivated";   reactome:R-HSA-8982021 "G alpha (z) in G alpha (z):RGS complex is inactivated";   reactome:R-HSA-8982025 "G alpha (q) in G (q):RGS complex is inactivated";   reactome:R-HSA-983422 "Disassembly of COPII coated vesicle"


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GTPase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ADSS1 adenylosuccinate synthase 1 JBrowse link 8 72,288,246 72,305,479 RGD:9068941
G AGAP1 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 JBrowse link 25 46,449,668 46,980,358 RGD:13508589
G AGAP2 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 JBrowse link 10 1,791,273 1,807,710 RGD:13508589
G AGAP3 ArfGAP with GTPase domain, ankyrin repeat and PH domain 3 JBrowse link 16 15,163,705 15,193,053 RGD:13508589
G ARHGAP35 Rho GTPase activating protein 35 JBrowse link 1 108,952,836 109,034,329 RGD:13508589
G ARHGAP5 Rho GTPase activating protein 5 JBrowse link 8 11,190,663 11,269,353 RGD:13508589
G ARHGDIB Rho GDP dissociation inhibitor beta JBrowse link 27 31,662,817 31,681,951 RGD:13508589
G ARL1 ADP ribosylation factor like GTPase 1 JBrowse link 15 40,390,091 40,401,043 RGD:13508589
G ARL2 ADP ribosylation factor like GTPase 2 JBrowse link 18 52,169,225 52,175,782 RGD:9068941
G ARL3 ADP ribosylation factor like GTPase 3 JBrowse link 28 15,152,762 15,189,043 RGD:9068941
G ARL6 ADP ribosylation factor like GTPase 6 JBrowse link 33 4,797,944 4,857,566 RGD:13508589
G ATL1 atlastin GTPase 1 JBrowse link 8 26,959,697 27,034,190 RGD:13508589
G ATL2 atlastin GTPase 2 JBrowse link 17 30,437,657 30,493,784 RGD:13508589
G ATL3 atlastin GTPase 3 JBrowse link 18 53,306,544 53,364,012 RGD:13508589
G BMS1 BMS1 ribosome biogenesis factor JBrowse link 28 4,178,625 4,235,749 RGD:13508589
G CDC42 cell division cycle 42 JBrowse link 2 77,153,276 77,169,947 RGD:13508589
G CPLANE2 ciliogenesis and planar polarity effector 2 JBrowse link 2 81,468,095 81,473,646 RGD:13508589
G CRACR2A calcium release activated channel regulator 2A JBrowse link 27 41,090,906 41,228,677 RGD:13508589
G DDX3X DEAD-box helicase 3 X-linked JBrowse link X 35,759,367 35,789,759 RGD:9068941
G DIRAS1 DIRAS family GTPase 1 JBrowse link 20 56,469,283 56,477,314 RGD:13508589
G DNAJC27 DnaJ heat shock protein family (Hsp40) member C27 JBrowse link 17 19,256,483 19,287,938 RGD:13508589
G DNM1 dynamin 1 JBrowse link 9 55,252,802 55,298,244 RGD:13508589
G DNM1L dynamin 1 like JBrowse link 27 16,161,855 16,211,983 RGD:13508589
G DNM2 dynamin 2 JBrowse link 20 50,398,866 50,487,303 RGD:13508589
G DNM3 dynamin 3 JBrowse link 7 26,569,708 27,024,939 RGD:13508589
G DRG1 developmentally regulated GTP binding protein 1 JBrowse link 26 24,327,714 24,350,782 RGD:13508589
G DRG2 developmentally regulated GTP binding protein 2 JBrowse link 5 41,428,233 41,445,706 RGD:13508589
G EEF1A1 eukaryotic translation elongation factor 1 alpha 1 JBrowse link 12 35,576,576 35,581,339 RGD:13508589
G EEF2 eukaryotic translation elongation factor 2 JBrowse link 20 55,577,413 55,586,422 RGD:13508589
G EEFSEC eukaryotic elongation factor, selenocysteine-tRNA specific JBrowse link 20 2,138,475 2,405,420 RGD:13508589
G EFL1 elongation factor like GTPase 1 JBrowse link 3 55,720,949 55,840,873 RGD:13508589
G EFTUD2 elongation factor Tu GTP binding domain containing 2 JBrowse link 9 18,585,918 18,631,743 RGD:13508589
G EIF2S3 eukaryotic translation initiation factor 2 subunit gamma JBrowse link X 19,662,132 19,680,223 RGD:13508589
G EIF5B eukaryotic translation initiation factor 5B JBrowse link 10 43,247,536 43,342,754 RGD:13508589
G ERAS ES cell expressed Ras JBrowse link X 42,024,867 42,029,649 RGD:13508589
G GBP1 guanylate binding protein 1 JBrowse link 6 59,378,069 59,393,388 RGD:13508589
G GBP5 guanylate binding protein 5 JBrowse link 6 59,273,699 59,292,563 RGD:13508589
G GBP6 guanylate binding protein family member 6 JBrowse link 6 59,150,665 59,170,070 RGD:13508589
G GCH1 GTP cyclohydrolase 1 JBrowse link 8 30,733,422 30,784,067 RGD:13508589
G GEM GTP binding protein overexpressed in skeletal muscle JBrowse link 29 39,016,543 39,037,761 RGD:13508589
G GFM1 G elongation factor mitochondrial 1 JBrowse link 23 51,940,307 51,983,196 RGD:13508589
G GFM2 GTP dependent ribosome recycling factor mitochondrial 2 JBrowse link 2 57,248,610 57,304,148 RGD:13508589
G GIMAP7 GTPase, IMAP family member 7 JBrowse link 16 14,811,427 14,820,441 RGD:9068941
G GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class) RGD:13508589
G GNA12 G protein subunit alpha 12 JBrowse link 6 14,375,144 14,476,018 RGD:13508589
G GNA13 G protein subunit alpha 13 JBrowse link 9 14,932,341 14,972,857 RGD:13508589
G GNA14 G protein subunit alpha 14 JBrowse link 1 80,992,992 81,178,362 RGD:13508589
G GNA15 G protein subunit alpha 15 JBrowse link 20 56,117,398 56,129,251 RGD:13508589
G GNAI1 G protein subunit alpha i1 JBrowse link 18 19,924,381 19,952,956 RGD:13508589
G GNAI2 G protein subunit alpha i2 JBrowse link 20 39,075,085 39,094,697 RGD:13508589
G GNAI3 G protein subunit alpha i3 JBrowse link 6 42,275,060 42,315,545 RGD:13508589
G GNAL G protein subunit alpha L JBrowse link 7 77,378,134 77,521,215 RGD:13508589
G GNAO1 G protein subunit alpha o1 JBrowse link 2 59,805,675 59,980,782 RGD:13508589
G GNAQ G protein subunit alpha q JBrowse link 1 80,733,530 80,928,065 RGD:13508589
G GNAS GNAS complex locus JBrowse link 24 43,643,409 43,658,641 RGD:13508589
G GNAT1 G protein subunit alpha transducin 1 JBrowse link 20 39,128,244 39,133,280 RGD:13508589
G GNAT2 G protein subunit alpha transducin 2 JBrowse link 6 42,259,404 42,271,197 RGD:13508589
G GNAT3 G protein subunit alpha transducin 3 JBrowse link 18 20,174,210 20,230,228 RGD:13508589
G GNAZ G protein subunit alpha z JBrowse link 26 27,780,598 27,811,688 RGD:13508589
G GNB1 G protein subunit beta 1 JBrowse link 5 56,777,854 56,879,619 RGD:13508589
G GNG10 G protein subunit gamma 10 JBrowse link 9 47,283,272 47,284,375 RGD:13508589
G GNG11 G protein subunit gamma 11 JBrowse link 14 19,426,916 19,431,232 RGD:13508589
G GNG12 G protein subunit gamma 12 JBrowse link 6 77,316,649 77,378,356 RGD:13508589
G GNG13 G protein subunit gamma 13 JBrowse link 6 39,800,092 39,806,959 RGD:13508589
G GNG14 G protein subunit gamma 14 JBrowse link 20 49,431,212 49,435,947 RGD:13508589
G GNG2 G protein subunit gamma 2 JBrowse link 8 28,080,699 28,194,464 RGD:13508589
G GNG3 G protein subunit gamma 3 JBrowse link 18 53,958,798 53,960,363 RGD:13508589
G GNG4 G protein subunit gamma 4 JBrowse link 4 4,308,892 4,389,812 RGD:13508589
G GNG5 G protein subunit gamma 5 JBrowse link 6 63,389,991 63,398,797 RGD:13508589
G GNG8 G protein subunit gamma 8 JBrowse link 1 109,266,884 109,268,515 RGD:13508589
G GNGT1 G protein subunit gamma transducin 1 JBrowse link 14 19,081,676 19,420,261 RGD:13508589
G GNGT2 G protein subunit gamma transducin 2 JBrowse link 9 25,369,751 25,374,812 RGD:13508589
G GNL1 G protein nucleolar 1 (putative) JBrowse link 12 375,485 383,713 RGD:13508589
G GPN2 GPN-loop GTPase 2 JBrowse link 2 73,251,139 73,261,806 RGD:13508589
G GPN3 GPN-loop GTPase 3 JBrowse link 26 8,279,100 8,291,584 RGD:13508589
G GSPT1 G1 to S phase transition 1 JBrowse link 6 30,931,937 30,971,699 RGD:13508589
G GSPT2 G1 to S phase transition 2 JBrowse link X 44,319,042 44,321,615 RGD:13508589
G GTPBP1 GTP binding protein 1 JBrowse link 10 26,074,969 26,103,520 RGD:13508589
G GTPBP2 GTP binding protein 2 JBrowse link 12 12,073,233 12,082,630 RGD:13508589
G GTPBP3 GTP binding protein 3, mitochondrial JBrowse link 20 45,422,653 45,427,434 RGD:13508589
G GTPBP4 GTP binding protein 4 JBrowse link 2 33,936,629 33,955,947 RGD:13508589
G GUF1 GUF1 homolog, GTPase JBrowse link 13 41,183,708 41,208,203 RGD:13508589
G HBS1L HBS1 like translational GTPase JBrowse link 1 27,704,375 27,791,376 RGD:13508589
G HRAS HRas proto-oncogene, GTPase JBrowse link 18 25,642,844 25,644,717 RGD:13508589
G IFGGC1 interferon-inducible GTPase 1-like JBrowse link 11 829,191 840,342 RGD:13508589
G IFT22 intraflagellar transport 22 JBrowse link 6 8,578,374 8,602,659 RGD:13508589
G IFT27 intraflagellar transport 27 JBrowse link 10 27,688,742 27,707,343 RGD:13508589
G KRAS KRAS proto-oncogene, GTPase JBrowse link 27 22,261,753 22,296,704 RGD:13508589
G LOC100684769 immunity-related GTPase family M protein 1 JBrowse link 11 920,516 957,869 RGD:13508589
G LOC100686305 GTP-binding nuclear protein Ran-like JBrowse link 35 26,048,567 26,049,642 RGD:13508589
G LOC100686869 ras-related protein Rab-13-like JBrowse link 5 22,405,665 22,406,278 RGD:13508589
G LOC100855995 tubulin alpha-8 chain-like JBrowse link 7 295,513 308,542 RGD:13508589
G LOC100856176 tubulin gamma-2 chain JBrowse link 9 20,322,054 20,326,696 RGD:13508589
G LOC100856405 tubulin alpha-1C chain JBrowse link 27 5,333,706 5,340,363 RGD:13508589
G LOC102153873 putative elongation factor 1-alpha-like 3 JBrowse link 14 51,518,300 51,520,960 RGD:13508589
G LOC102155289 elongation factor 1-alpha 1 JBrowse link 3 60,899,797 60,901,258 RGD:13508589
G LOC106557476 tubulin alpha-1A chain JBrowse link 27 5,407,906 5,412,265 RGD:13508589
G LOC106559713 elongation factor 1-alpha 1 pseudogene JBrowse link 14 11,504,986 11,506,577 RGD:13508589
G LOC111094220 elongation factor 1-alpha 1 pseudogene JBrowse link 36 11,753,538 11,754,932 RGD:13508589
G LOC475707 GPN-loop GTPase 1 JBrowse link 17 21,654,516 21,678,435 RGD:13508589
G LOC477570 tubulin alpha-3 chain-like JBrowse link 26 30,485,958 30,497,638 RGD:13508589
G LOC478701 tubulin beta-2A chain JBrowse link 35 3,448,402 3,450,783 RGD:13508589
G LOC485916 ras homolog gene family, member C pseudogene JBrowse link 24 35,234,250 35,234,861 RGD:13508589
G LOC487375 elongation factor 1-alpha 1-like JBrowse link 2 75,787,450 75,797,662 RGD:13508589
G LOC607762 GPN-loop GTPase 1-like RGD:13508589
G LOC608051 tubulin alpha-3 chain JBrowse link 26 30,428,955 30,437,431 RGD:13508589
G LOC608308 GPN-loop GTPase 1-like JBrowse link 17 21,545,586 21,564,681 RGD:13508589
G LOC610048 pre-rRNA-processing protein TSR1 homolog JBrowse link 12 16,856,138 16,860,100 RGD:13508589
G LOC610636 tubulin alpha-1B chain JBrowse link 37 25,811,491 25,818,838 RGD:13508589
G LRP10 LDL receptor related protein 10 JBrowse link 8 3,208,710 3,214,888 RGD:13508589
G LRRK2 leucine rich repeat kinase 2 JBrowse link 27 13,282,824 13,420,917 RGD:13508589
G LSG1 large 60S subunit nuclear export GTPase 1 JBrowse link 33 31,078,384 31,117,093 RGD:13508589
G MFN1 mitofusin 1 JBrowse link 34 12,785,799 12,816,881 RGD:13508589
G MFN2 mitofusin 2 JBrowse link 2 84,284,719 84,310,715 RGD:13508589
G MMAA metabolism of cobalamin associated A JBrowse link 15 44,221,082 44,243,530 RGD:13508589
G MMUT methylmalonyl-CoA mutase JBrowse link 12 17,306,074 17,339,921 RGD:13508589
G MRAS muscle RAS oncogene homolog JBrowse link 23 34,558,278 34,613,987 RGD:13508589
G MTFMT mitochondrial methionyl-tRNA formyltransferase JBrowse link 30 29,388,600 29,415,578 RGD:13508589
G MTG1 mitochondrial ribosome associated GTPase 1 RGD:13508589
G MTG2 mitochondrial ribosome associated GTPase 2 JBrowse link 24 46,216,653 46,229,400 RGD:13508589
G MTIF2 mitochondrial translational initiation factor 2 JBrowse link 10 56,136,231 56,157,940 RGD:13508589
G MX1 MX dynamin like GTPase 1 JBrowse link 31 35,898,206 35,929,802 RGD:13508589
G MX2 MX dynamin like GTPase 2 JBrowse link 31 35,860,596 35,883,607 RGD:13508589
G NKIRAS1 NFKB inhibitor interacting Ras like 1 JBrowse link 23 19,829,764 19,861,462 RGD:13508589
G NKIRAS2 NFKB inhibitor interacting Ras like 2 JBrowse link 9 20,851,014 20,854,953 RGD:13508589
G NLRP10 NLR family pyrin domain containing 10 JBrowse link 21 31,500,718 31,518,337 RGD:13508589
G NRAS NRAS proto-oncogene, GTPase JBrowse link 17 52,411,733 52,418,788 RGD:13508589
G NUDT1 nudix hydrolase 1 JBrowse link 6 14,874,459 14,881,517 RGD:13508589
G NUGGC nuclear GTPase, germinal center associated JBrowse link 25 29,507,198 29,561,565 RGD:13508589
G OPA1 OPA1 mitochondrial dynamin like GTPase JBrowse link 23 52,068,123 52,154,410 RGD:13508589
G PEX26 peroxisomal biogenesis factor 26 JBrowse link 27 45,675,537 45,688,026 RGD:13508589
G PVALB parvalbumin JBrowse link 10 27,655,896 27,674,309 RGD:13508589
G RAB10 RAB10, member RAS oncogene family JBrowse link 17 20,181,363 20,264,927 RGD:13508589
G RAB11A RAB11A, member RAS oncogene family JBrowse link 30 30,200,831 30,218,412 RGD:13508589
G RAB11B RAB11B, member RAS oncogene family JBrowse link 20 52,955,949 52,966,279 RGD:13508589
G RAB12 RAB12, member RAS oncogene family JBrowse link 7 74,752,697 74,791,872 RGD:13508589
G RAB13 RAB13, member RAS oncogene family JBrowse link 7 43,152,903 43,156,720 RGD:13508589
G RAB14 RAB14, member RAS oncogene family JBrowse link 11 74,157,497 74,172,817 RGD:13508589
G RAB15 RAB15, member RAS oncogene family JBrowse link 8 39,329,754 39,364,000 RGD:13508589
G RAB17 RAB17, member RAS oncogene family JBrowse link 25 48,181,557 48,220,729 RGD:13508589
G RAB18 RAB18, member RAS oncogene family JBrowse link 2 6,071,944 6,112,064 RGD:13508589
G RAB19 RAB19, member RAS oncogene family JBrowse link 16 8,544,353 8,562,714 RGD:13508589
G RAB1A RAB1A, member RAS oncogene family JBrowse link 10 64,564,351 64,590,654 RGD:13508589
G RAB1B RAB1B, member RAS oncogene family JBrowse link 18 51,026,975 51,034,356 RGD:13508589
G RAB20 RAB20, member RAS oncogene family JBrowse link 22 58,825,147 58,853,921 RGD:13508589
G RAB21 RAB21, member RAS oncogene family JBrowse link 10 13,288,103 13,328,246 RGD:13508589
G RAB22A RAB22A, member RAS oncogene family JBrowse link 24 43,109,489 43,157,932 RGD:13508589
G RAB23 RAB23, member RAS oncogene family JBrowse link 12 24,388,530 24,438,956 RGD:13508589
G RAB24 RAB24, member RAS oncogene family JBrowse link 4 36,055,190 36,059,945 RGD:13508589
G RAB25 RAB25, member RAS oncogene family JBrowse link 7 41,752,975 41,758,954 RGD:13508589
G RAB26 RAB26, member RAS oncogene family JBrowse link 6 38,806,750 38,812,541 RGD:13508589
G RAB27A RAB27A, member RAS oncogene family JBrowse link 30 20,633,576 20,706,240 RGD:13508589
G RAB27B RAB27B, member RAS oncogene family JBrowse link 1 20,695,100 20,832,745 RGD:13508589
G RAB28 RAB28, member RAS oncogene family JBrowse link 3 66,601,543 66,738,055 RGD:13508589
G RAB29 RAB29, member RAS oncogene family JBrowse link 38 2,196,618 2,204,150 RGD:13508589
G RAB2A RAB2A, member RAS oncogene family JBrowse link 29 10,953,425 11,042,789 RGD:13508589
G RAB2B RAB2B, member RAS oncogene family JBrowse link 15 18,494,417 18,512,144 RGD:13508589
G RAB30 RAB30, member RAS oncogene family JBrowse link 21 16,097,726 16,187,910 RGD:13508589
G RAB31 RAB31, member RAS oncogene family JBrowse link 7 75,678,896 75,807,716 RGD:13508589
G RAB32 RAB32, member RAS oncogene family JBrowse link 1 37,706,809 37,719,044 RGD:13508589
G RAB33A RAB33A, member RAS oncogene family JBrowse link X 101,311,752 101,322,825 RGD:13508589
G RAB33B RAB33B, member RAS oncogene family JBrowse link 19 3,256,790 3,273,198 RGD:13508589
G RAB34 RAB34, member RAS oncogene family JBrowse link 9 42,909,843 42,913,935 RGD:13508589
G RAB35 RAB35, member RAS oncogene family JBrowse link 26 16,061,872 16,078,489 RGD:13508589
G RAB36 RAB36, member RAS oncogene family JBrowse link 26 27,831,256 27,845,918 RGD:13508589
G RAB37 RAB37, member RAS oncogene family JBrowse link 9 5,680,927 5,736,037 RGD:13508589
G RAB38 RAB38, member RAS oncogene family JBrowse link 21 11,769,924 11,823,546 RGD:13508589
G RAB39A RAB39A, member RAS oncogene family JBrowse link 5 24,516,541 24,546,743 RGD:13508589
G RAB39B RAB39B, member RAS oncogene family JBrowse link X 123,245,227 123,251,283 RGD:13508589
G RAB3A RAB3A, member RAS oncogene family JBrowse link 20 44,796,740 44,802,224 RGD:13508589
G RAB3B RAB3B, member RAS oncogene family JBrowse link 15 9,305,495 9,378,003 RGD:13508589
G RAB3C RAB3C, member RAS oncogene family JBrowse link 2 45,459,068 45,731,994 RGD:13508589
G RAB3D RAB3D, member RAS oncogene family JBrowse link 20 49,974,592 49,985,362 RGD:13508589
G RAB40B RAB40B, member RAS oncogene family RGD:13508589
G RAB40C RAB40C, member RAS oncogene family JBrowse link 6 39,937,858 39,968,042 RGD:13508589
G RAB42 RAB42, member RAS oncogene family JBrowse link 2 71,906,453 71,908,072 RGD:13508589
G RAB43 RAB43, member RAS oncogene family JBrowse link 20 2,979,094 3,020,496 RGD:13508589
G RAB44 RAB44, member RAS oncogene family JBrowse link 12 5,769,056 5,804,963 RGD:13508589
G RAB4A RAB4A, member RAS oncogene family JBrowse link 4 9,914,681 9,965,468 RGD:13508589
G RAB4B RAB4B, member RAS oncogene family JBrowse link 1 113,003,317 113,011,978 RGD:13508589
G RAB5A RAB5A, member RAS oncogene family JBrowse link 23 23,303,650 23,333,571 RGD:13508589
G RAB5B RAB5B, member RAS oncogene family JBrowse link 10 307,693 325,766 RGD:13508589
G RAB5C RAB5C, member RAS oncogene family JBrowse link 9 20,754,264 20,776,941 RGD:13508589
G RAB6A RAB6A, member RAS oncogene family JBrowse link 21 24,489,653 24,578,212 RGD:13508589
G RAB6B RAB6B, member RAS oncogene family JBrowse link 23 30,714,723 30,754,765 RGD:13508589
G RAB7A RAB7A, member RAS oncogene family JBrowse link 20 2,704,716 2,776,518 RGD:13508589
G RAB7B RAB7B, member RAS oncogene family JBrowse link 38 2,333,939 2,359,531 RGD:13508589
G RAB8A RAB8A, member RAS oncogene family JBrowse link 20 46,334,601 46,351,907 RGD:13508589
G RAB8B RAB8B, member RAS oncogene family JBrowse link 30 27,784,298 27,845,901 RGD:13508589
G RAB9A RAB9A, member RAS oncogene family JBrowse link X 10,072,764 10,124,620 RGD:13508589
G RAB9B RAB9B, member RAS oncogene family JBrowse link X 77,228,609 77,238,344 RGD:13508589
G RABL2B RAB, member of RAS oncogene family like 2B JBrowse link 10 16,555,009 16,571,207 RGD:13508589
G RABL3 RAB, member of RAS oncogene family like 3 JBrowse link 33 24,107,754 24,151,378 RGD:13508589
G RAC1 Rac family small GTPase 1 JBrowse link 6 11,726,259 11,758,532 RGD:13508589
G RAC2 Rac family small GTPase 2 JBrowse link 10 27,295,597 27,311,864 RGD:13508589
G RAC3 Rac family small GTPase 3 JBrowse link 9 293,260 295,990 RGD:9068941
G RALA RAS like proto-oncogene A JBrowse link 18 10,022,490 10,047,583 RGD:13508589
G RALB RAS like proto-oncogene B JBrowse link 19 29,820,006 29,868,345 RGD:13508589
G RAN RAN, member RAS oncogene family JBrowse link 26 1,435,077 1,436,893 RGD:13508589
G RAN RAN, member RAS oncogene family JBrowse link 30 22,170,896 22,171,572 RGD:13508589
G RAP1A RAP1A, member of RAS oncogene family JBrowse link 17 63,725,812 63,795,359 RGD:13508589
G RAP1B RAP1B, member of RAS oncogene family JBrowse link 10 10,805,359 10,816,839 RGD:13508589
G RAP2A RAP2A, member of RAS oncogene family JBrowse link 22 47,777,621 47,814,061 RGD:13508589
G RAP2B RAP2B, member of RAS oncogene family JBrowse link 23 47,503,382 47,508,900 RGD:13508589
G RAP2C RAP2C, member of RAS oncogene family JBrowse link X 103,134,752 103,150,900 RGD:13508589
G RASD1 ras related dexamethasone induced 1 JBrowse link 5 41,965,091 41,966,812 RGD:13508589
G RASD2 RASD family member 2 JBrowse link 10 28,626,761 28,637,861 RGD:13508589
G RASEF RAS and EF-hand domain containing JBrowse link 1 76,257,108 76,468,515 RGD:13508589
G RASL10A RAS like family 10 member A JBrowse link 26 22,620,755 22,623,251 RGD:13508589
G RASL10B RAS like family 10 member B JBrowse link 9 37,926,974 37,938,474 RGD:13508589
G RASL11A RAS like family 11 member A JBrowse link 25 12,316,034 12,318,740 RGD:13508589
G RASL11B RAS like family 11 member B JBrowse link 13 45,579,587 45,583,945 RGD:13508589
G REM1 RRAD and GEM like GTPase 1 JBrowse link 24 20,991,166 21,000,019 RGD:13508589
G REM2 RRAD and GEM like GTPase 2 JBrowse link 8 3,215,023 3,223,470 RGD:13508589
G RERG RAS like estrogen regulated growth inhibitor JBrowse link 27 31,413,464 31,526,838 RGD:13508589
G RERGL RERG like JBrowse link 27 28,943,933 28,959,374 RGD:13508589
G RHEB Ras homolog, mTORC1 binding JBrowse link 16 15,439,910 15,483,489 RGD:13508589
G RHEBL1 RHEB like 1 JBrowse link 27 5,509,640 5,512,893 RGD:13508589
G RHOA ras homolog family member A JBrowse link 20 39,824,552 39,888,089 RGD:13508589
G RHOB ras homolog family member B JBrowse link 17 15,438,744 15,439,793 RGD:13508589
G RHOBTB1 Rho related BTB domain containing 1 JBrowse link 4 12,971,624 13,089,520 RGD:13508589
G RHOBTB2 Rho related BTB domain containing 2 JBrowse link 25 34,299,363 34,329,052 RGD:13508589
G RHOBTB3 Rho related BTB domain containing 3 JBrowse link 3 13,823,607 13,879,663 RGD:13508589
G RHOC ras homolog family member C JBrowse link 17 62,868,373 62,872,322 RGD:13508589
G RHOD ras homolog family member D JBrowse link 18 50,320,428 50,330,108 RGD:13508589
G RHOF ras homolog family member F, filopodia associated JBrowse link 26 7,476,753 7,489,427 RGD:13508589
G RHOG ras homolog family member G JBrowse link 21 26,371,868 26,373,395 RGD:13508589
G RHOG2 RHOG family member 2 JBrowse link X 55,679,373 55,689,161 RGD:13508589
G RHOH ras homolog family member H JBrowse link 3 72,272,446 72,277,015 RGD:13508589
G RHOJ ras homolog family member J JBrowse link 8 37,803,460 37,880,411 RGD:13508589
G RHOQ ras homolog family member Q JBrowse link 10 48,766,623 48,807,198 RGD:13508589
G RHOT1 ras homolog family member T1 JBrowse link 9 40,715,713 40,779,551 RGD:13508589
G RHOT2 ras homolog family member T2 JBrowse link 6 39,900,889 39,905,624 RGD:13508589
G RHOU ras homolog family member U JBrowse link 4 10,395,033 10,406,239 RGD:13508589
G RHOV ras homolog family member V JBrowse link 30 8,003,279 8,005,366 RGD:13508589
G RIT1 Ras like without CAAX 1 JBrowse link 7 41,894,726 41,903,450 RGD:13508589
G RIT2 Ras like without CAAX 2 JBrowse link 7 47,597,746 48,064,202 RGD:13508589
G RND1 Rho family GTPase 1 JBrowse link 27 5,679,629 5,686,657 RGD:13508589
G RND2 Rho family GTPase 2 JBrowse link 9 20,037,469 20,041,044 RGD:13508589
G RND3 Rho family GTPase 3 JBrowse link 19 51,889,693 51,909,028 RGD:13508589
G RNF112 ring finger protein 112 JBrowse link 5 40,792,049 40,798,534 RGD:13508589
G RRAD RRAD, Ras related glycolysis inhibitor and calcium channel regulator JBrowse link 5 82,392,608 82,395,574 RGD:13508589
G RRAGA Ras related GTP binding A JBrowse link 11 38,886,990 38,888,634 RGD:9068941
G RRAGB Ras related GTP binding B JBrowse link X 47,323,427 47,361,551 RGD:13508589
G RRAGC Ras related GTP binding C JBrowse link 15 3,875,193 3,892,501 RGD:13508589
G RRAGD Ras related GTP binding D JBrowse link 12 48,583,350 48,625,032 RGD:13508589
G RRAS RAS related JBrowse link 1 106,895,413 106,899,265 RGD:13508589
G RRAS2 RAS related 2 JBrowse link 21 37,037,576 37,119,733 RGD:13508589
G SAR1B secretion associated Ras related GTPase 1B JBrowse link 11 22,713,459 22,743,190 RGD:13508589
G SEPTIN1 septin 1 JBrowse link 6 17,714,929 17,718,972 RGD:13508589
G SEPTIN10 septin 10 JBrowse link 10 34,248,173 34,304,888 RGD:13508589
G SEPTIN11 septin 11 JBrowse link 32 1,553,208 1,608,132 RGD:13508589
G SEPTIN12 septin 12 JBrowse link 6 36,630,038 36,641,920 RGD:13508589
G SEPTIN14 septin 14 JBrowse link 18 25,103,092 25,201,880 RGD:13508589
G SEPTIN2 septin 2 JBrowse link 25 51,296,486 51,330,508 RGD:13508589
G SEPTIN3 septin 3 JBrowse link 10 23,370,393 23,396,922 RGD:13508589
G SEPTIN4 septin 4 JBrowse link 9 33,138,167 33,162,212 RGD:13508589
G SEPTIN5 septin 5 JBrowse link 26 29,568,776 29,573,837 RGD:13508589
G SEPTIN6 septin 6 JBrowse link X 91,647,293 91,714,379 RGD:13508589
G SEPTIN7 septin 7 JBrowse link 14 47,395,704 47,494,873 RGD:13508589
G SEPTIN8 septin 8 JBrowse link 11 21,052,833 21,078,721 RGD:13508589
G SEPTIN9 septin 9 JBrowse link 9 3,495,764 3,571,755 RGD:13508589
G SRP54 signal recognition particle 54 JBrowse link 8 13,800,275 13,837,799 RGD:13508589
G SRPRA SRP receptor subunit alpha JBrowse link 5 8,247,608 8,253,411 RGD:13508589
G TBCC tubulin folding cofactor C JBrowse link 12 11,332,736 11,334,799 RGD:13508589
G TCF25 transcription factor 25 JBrowse link 5 63,697,627 63,729,780 RGD:13508589
G TMEM250 transmembrane protein 250 JBrowse link 9 49,308,397 49,311,360 RGD:13508589
G TPPP tubulin polymerization promoting protein JBrowse link 34 11,633,054 11,645,585 RGD:9068941
G TRIM23 tripartite motif containing 23 JBrowse link 2 51,323,341 51,360,193 RGD:13508589
G TSR1 TSR1 ribosome maturation factor JBrowse link 9 46,421,656 46,432,938 RGD:13508589
G TUBA4A tubulin alpha 4a JBrowse link 37 25,799,075 25,803,257 RGD:13508589
G TUBA8 tubulin alpha 8 JBrowse link 27 45,706,576 45,725,679 RGD:13508589
G TUBAL3 tubulin alpha like 3 JBrowse link 2 30,523,678 30,531,909 RGD:13508589
G TUBB tubulin beta class I JBrowse link 12 512,738 517,154 RGD:13508589
G TUBB1 tubulin beta 1 class VI JBrowse link 24 43,759,078 43,768,556 RGD:13508589
G TUBB2B tubulin beta 2B class IIb JBrowse link 35 3,494,982 3,498,274 RGD:13508589
G TUBB3 tubulin beta 3 class III JBrowse link 5 63,681,765 63,690,898 RGD:13508589
G TUBB4A tubulin beta 4A class IVa JBrowse link 20 53,697,643 53,702,671 RGD:13508589
G TUBB4B tubulin beta 4B class IVb JBrowse link 9 48,432,114 48,434,626 RGD:13508589
G TUBB6 tubulin beta 6 class V JBrowse link 7 77,728,876 77,746,759 RGD:13508589
G TUBD1 tubulin delta 1 JBrowse link 9 34,355,285 34,387,084 RGD:13508589
G TUBE1 tubulin epsilon 1 JBrowse link 12 68,499,435 68,514,127 RGD:13508589
G TUBG1 tubulin, gamma 1 JBrowse link 9 20,358,683 20,363,455 RGD:13508589
G TUFM Tu translation elongation factor, mitochondrial JBrowse link 6 18,357,223 18,360,929 RGD:13508589
G WDR90 WD repeat domain 90 JBrowse link 6 39,906,403 39,921,516 RGD:13508589

Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 16929
    catalytic activity 5372
      hydrolase activity 2314
        hydrolase activity, acting on acid anhydrides 777
          hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 775
            pyrophosphatase activity 773
              nucleoside-triphosphatase activity 718
                GTPase activity 285
                  GTPase motor activity + 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.