ONTOLOGY REPORT - ANNOTATIONS
Term: DNA topoisomerase activity
Accession: GO:0003916
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Definition: Catalysis of the transient cleavage and passage of individual DNA strands or double helices through one another, resulting a topological transformation in double-stranded DNA.
Synonyms: alt_id: GO:0009387
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LOC101702367
DNA topoisomerase 2-alpha
enables
IEA
UniProt
GO_REF:0000043
NCBI chrNW_004624795:2,903,686...2,927,028
Ensembl chrNW_004624795:2,898,038...2,926,049
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Spo11
SPO11 initiator of meiotic double strand breaks
enables
IEA
UniProt
GO_REF:0000043
NCBI chrNW_004624741:23,784,362...23,800,127
Ensembl chrNW_004624741:23,784,298...23,800,168
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Top1
DNA topoisomerase I
enables
IEA
UniProt
GO_REF:0000043
NCBI chrNW_004624919:1,668,712...1,756,624
Ensembl chrNW_004624919:1,668,440...1,756,629
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Top2b
DNA topoisomerase II beta
enables
IEA
UniProt
GO_REF:0000043
NCBI chrNW_004624788:3,493,188...3,590,138
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Top3a
DNA topoisomerase III alpha
enables
IEA
UniProt
GO_REF:0000043
NCBI chrNW_004624849:3,159,432...3,196,235
Ensembl chrNW_004624849:3,159,810...3,194,860
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Top3b
DNA topoisomerase III beta
enables
IEA
UniProt
GO_REF:0000043
NCBI chrNW_004624747:1,450,236...1,473,467
Ensembl chrNW_004624747:1,446,412...1,473,600
G
LOC101702367
DNA topoisomerase 2-alpha
enables
IEA
UniProt
GO_REF:0000003
NCBI chrNW_004624795:2,903,686...2,927,028
Ensembl chrNW_004624795:2,898,038...2,926,049
G
Top2b
DNA topoisomerase II beta
enables
IEA
UniProt
GO_REF:0000003
NCBI chrNW_004624788:3,493,188...3,590,138
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Top1
DNA topoisomerase I
enables
ISO IEA
RGD UniProt InterPro TreeGrafter
PMID:1332866
GO_REF:0000002 GO_REF:0000003 GO_REF:0000104 GO_REF:0000118 RGD:1580856
NCBI chrNW_004624919:1,668,712...1,756,624
Ensembl chrNW_004624919:1,668,440...1,756,629
G
Top3a
DNA topoisomerase III alpha
enables
IEA
UniProt InterPro TreeGrafter
GO_REF:0000002 GO_REF:0000003 GO_REF:0000118
NCBI chrNW_004624849:3,159,432...3,196,235
Ensembl chrNW_004624849:3,159,810...3,194,860
G
Top3b
DNA topoisomerase III beta
enables
IEA
InterPro UniProt TreeGrafter
GO_REF:0000002 GO_REF:0000003 GO_REF:0000118
NCBI chrNW_004624747:1,450,236...1,473,467
Ensembl chrNW_004624747:1,446,412...1,473,600
G
LOC101702367
DNA topoisomerase 2-alpha
enables
IEA
UniProt InterPro
GO_REF:0000002 GO_REF:0000104 GO_REF:0000117
NCBI chrNW_004624795:2,903,686...2,927,028
Ensembl chrNW_004624795:2,898,038...2,926,049
G
Spo11
SPO11 initiator of meiotic double strand breaks
enables
IEA
InterPro
GO_REF:0000002
NCBI chrNW_004624741:23,784,362...23,800,127
Ensembl chrNW_004624741:23,784,298...23,800,168
G
Top2b
DNA topoisomerase II beta
enables
IEA
UniProt InterPro
GO_REF:0000002 GO_REF:0000104 GO_REF:0000117
NCBI chrNW_004624788:3,493,188...3,590,138
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