ONTOLOGY REPORT - ANNOTATIONS
Term: DNA topoisomerase activity
Accession: GO:0003916
browse the term
Definition: Catalysis of the transient cleavage and passage of individual DNA strands or double helices through one another, resulting a topological transformation in double-stranded DNA.
Synonyms: alt_id: GO:0009387
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Top2a
DNA topoisomerase II alpha
IDA
RGD
PMID:11334111
RGD:1580614
NCBI chr10:83,945,731...83,976,874
Ensembl chr10:83,945,735...83,976,874
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Top1
DNA topoisomerase I
enables
IDA ISO IBA IEA
(PMID:16261531), (PMID:7842491), (PMID:9094096) GO_REF:0000033 GO_REF:0000104 (PMID:14594810), (PMID:14654701), (PMID:17355975), (PMID:8567649), (PMID:8631793), (PMID:8631794), (PMID:9611241) GO_REF:0000003
RGD GO_Central UniProt
PMID:7842491 PMID:8567649 PMID:8631793 PMID:8631794 PMID:9094096 PMID:9611241 PMID:14594810 PMID:14654701 PMID:16261531 PMID:17355975 PMID:1332866 More...
GO_REF:0000003 GO_REF:0000033 GO_REF:0000104, RGD:1580856
NCBI chr 3:149,293,469...149,376,618
Ensembl chr 3:149,293,403...149,376,623
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Top1mt
DNA topoisomerase I mitochondrial
enables
IEA IBA
GO_REF:0000003 GO_REF:0000033 GO_REF:0000104
UniProt GO_Central
GO_REF:0000003 GO_REF:0000033 GO_REF:0000104
NCBI chr 7:107,338,092...107,368,125
Ensembl chr 7:107,342,527...107,366,049
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Top3a
DNA topoisomerase III alpha
enables
ISO IBA
(PMID:20445207) GO_REF:0000033
RGD GO_Central
PMID:20445207
GO_REF:0000033
NCBI chr10:45,419,219...45,457,356
Ensembl chr10:45,419,217...45,457,559
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Top3b
DNA topoisomerase III beta
enables
IBA
GO_REF:0000033
GO_Central
GO_REF:0000033
NCBI chr11:84,097,018...84,125,474
Ensembl chr11:84,097,026...84,125,392
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Spo11
SPO11 initiator of meiotic double strand breaks
enables
IEA
GO_REF:0000002
InterPro
GO_REF:0000002
NCBI chr 3:161,755,299...161,770,930
Ensembl chr 3:161,757,519...161,770,925
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Top2a
DNA topoisomerase II alpha
enables
IDA ISO IEA
(PMID:12711669), (PMID:16611985) GO_REF:0000003 GO_REF:0000117 SGD:S000005032 (PMID:1331984), (PMID:7842491), (PMID:7937150), (PMID:9094096)
RGD UniProt
PMID:1331984 PMID:7842491 PMID:7937150 PMID:9094096 PMID:12711669 PMID:16611985 PMID:11334111 More...
GO_REF:0000003 GO_REF:0000117, RGD:1580614
NCBI chr10:83,945,731...83,976,874
Ensembl chr10:83,945,735...83,976,874
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Top2b
DNA topoisomerase II beta
enables
ISO
(PMID:10684600), (PMID:31409799), (PMID:32128574) (MGI:6362312|PMID:31409799) (PMID:31409799)
RGD
PMID:10684600 PMID:31409799 PMID:32128574
MGI:6362312
NCBI chr15:9,051,340...9,111,721
Ensembl chr15:9,051,341...9,112,085
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