ONTOLOGY REPORT - ANNOTATIONS |
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Term: | DNA (cytosine-5-)-methyltransferase activity |
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Accession: | GO:0003886
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browse the term
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Definition: | Catalysis of the reaction: a 2'-deoxycytidine in DNA + S-adenosyl-L-methionine = a 5-methyl-2'-deoxycytidine in DNA + H+ + S-adenosyl-L-homocysteine. |
Synonyms: | narrow_synonym: | site-specific DNA-methyltransferase (cytosine-specific) activity |
| broad_synonym: | cytosine DNA methylase activity; cytosine DNA methyltransferase activity; deoxyribonucleic methylase activity |
| related_synonym: | DNA 5-cytosine methylase activity; DNA cytosine C(5) methylase activity; DNA cytosine C5 methylase activity; S-adenosyl-L-methionine:DNA (cytosine-5-)-methyltransferase activity; cytosine 5-methyltransferase activity; cytosine-specific DNA methyltransferase activity; deoxyribonucleic (cytosine-5-)-methyltransferase activity; deoxyribonucleic acid (cytosine-5-)-methyltransferase activity; methylphosphotriester-DNA methyltransferase activity; modification methylase activity; restriction-modification system activity; type II DNA methylase activity |
| alt_id: | GO:0008326 |
| xref: | EC:2.1.1.37; MetaCyc:DNA-CYTOSINE-5--METHYLTRANSFERASE-RXN; RHEA:13681 |
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DNMT1 |
DNA methyltransferase 1 |
enables |
ISO IBA IEA TAS IDA |
(PMID:8940105) (PMID:21745816) |
RGD GO_Central InterPro PINC UniProt RHEA Ensembl |
PMID:8940105 PMID:12473678 PMID:21745816 |
GO_REF:0000002 GO_REF:0000033 GO_REF:0000104 GO_REF:0000107 GO_REF:0000116 RGD:1359078 |
NCBI chr19:10,133,346...10,194,953
Ensembl chr19:10,133,342...10,231,286
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DNMT3A |
DNA methyltransferase 3 alpha |
enables |
IDA IEA IBA |
(PMID:12138111), (PMID:19786833) |
ARUK-UCL Ensembl RHEA GO_Central |
PMID:12138111 PMID:19786833 |
GO_REF:0000033 GO_REF:0000107 GO_REF:0000116 |
NCBI chr 2:25,227,874...25,342,590
Ensembl chr 2:25,227,855...25,342,590
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DNMT3B |
DNA methyltransferase 3 beta |
enables |
IEA TAS IDA NAS |
(PMID:10433969) (PMID:16543361) (PMID:10647011) |
RHEA UniProt MGI |
PMID:10433969 PMID:10647011 PMID:16543361 |
GO_REF:0000116 |
NCBI chr20:32,762,385...32,809,356
Ensembl chr20:32,762,385...32,809,359
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DNMT3L |
DNA methyltransferase 3 like |
NOT|enables |
ISO |
(PMID:11934864) |
MGI |
PMID:11934864 |
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NCBI chr21:44,246,339...44,261,897
Ensembl chr21:44,246,339...44,262,216
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DNMT3B |
DNA methyltransferase 3 beta |
enables |
IBA |
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GO_Central |
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GO_REF:0000033 |
NCBI chr20:32,762,385...32,809,356
Ensembl chr20:32,762,385...32,809,359
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G |
DNMT1 |
DNA methyltransferase 1 |
enables |
IEA |
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UniProt |
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GO_REF:0000003 |
NCBI chr19:10,133,346...10,194,953
Ensembl chr19:10,133,342...10,231,286
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G |
DNMT3A |
DNA methyltransferase 3 alpha |
enables |
IEA |
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UniProt |
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GO_REF:0000003 |
NCBI chr 2:25,227,874...25,342,590
Ensembl chr 2:25,227,855...25,342,590
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G |
DNMT3B |
DNA methyltransferase 3 beta |
enables |
IEA |
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UniProt |
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GO_REF:0000003 |
NCBI chr20:32,762,385...32,809,356
Ensembl chr20:32,762,385...32,809,359
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G |
DNMT1 |
DNA methyltransferase 1 |
enables |
IEA |
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UniProt |
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GO_REF:0000003 |
NCBI chr19:10,133,346...10,194,953
Ensembl chr19:10,133,342...10,231,286
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G |
DNMT3A |
DNA methyltransferase 3 alpha |
enables |
IEA |
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UniProt |
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GO_REF:0000003 |
NCBI chr 2:25,227,874...25,342,590
Ensembl chr 2:25,227,855...25,342,590
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G |
DNMT3B |
DNA methyltransferase 3 beta |
enables |
IEA |
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UniProt |
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GO_REF:0000003 |
NCBI chr20:32,762,385...32,809,356
Ensembl chr20:32,762,385...32,809,359
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