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ONTOLOGY REPORT - ANNOTATIONS

Term:peptidyl-prolyl cis-trans isomerase activity
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Accession:GO:0003755 term browser browse the term
Definition:Catalysis of the reaction: peptidyl-proline (omega=180) = peptidyl-proline (omega=0).
Synonyms:exact_synonym: cis-trans proline isomerase activity
 narrow_synonym: FK506-sensitive peptidyl-prolyl cis-trans isomerase;   cyclophilin-type peptidyl-prolyl cis-trans isomerase activity;   juglone-sensitive cis-trans proline isomerase activity;   juglone-sensitive peptidyl-prolyl cis-trans isomerase activity
 related_synonym: PPIase activity;   cyclophilin activity;   immunophilin;   parvulin;   peptide bond isomerase activity;   peptidyl-prolyl isomerase B reaction;   peptidylproline cis-trans-isomerase activity;   peptidylprolyl cis-trans isomerase activity;   peptidylprolyl isomerase activity;   rotamase activity
 alt_id: GO:0004752;   GO:0042028
 xref: EC:5.2.1.8;   MetaCyc:PEPTIDYLPROLYL-ISOMERASE-RXN;   RHEA:16237;   reactome:R-HSA-2022073 "Procollagen triple helix formation";   reactome:R-HSA-9626816 "PIN1 binds p-S345-NCF1"

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peptidyl-prolyl cis-trans isomerase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cwc27 CWC27 spliceosome associated cyclophilin NOT|enables ISO (PMID:20676357) UniProt PMID:20676357 NCBI chrNW_004955446:4,032,493...4,230,444
Ensembl chrNW_004955446:4,032,347...4,230,444 		JBrowse link
G Fkbp10 FKBP prolyl isomerase 10 enables ISO (PMID:7493967) MGI PMID:7493967 NCBI chrNW_004955451:16,025,008...16,031,950
Ensembl chrNW_004955451:16,025,008...16,035,976 		JBrowse link
G Fkbp15 FKBP prolyl isomerase family member 15 NOT|enables ISO (PMID:16756961) MGI PMID:16756961 NCBI chrNW_004955419:14,264,488...14,329,890
Ensembl chrNW_004955419:14,264,577...14,319,008 		JBrowse link
G Fkbp1a FKBP prolyl isomerase 1A enables ISO (PMID:1696686), (PMID:1701173), (PMID:2477715) BHF-UCL PMID:1696686 PMID:1701173 PMID:2477715 NCBI chrNW_004955596:580,106...606,210
Ensembl chrNW_004955596:580,106...603,255 		JBrowse link
G Fkbp1b FKBP prolyl isomerase 1B enables ISO (PMID:7513996), (PMID:7592869)
(PMID:16481613)		 BHF-UCL
MGI		 PMID:7513996 PMID:7592869 PMID:16481613 NCBI chrNW_004955469:6,263,271...6,274,823
Ensembl chrNW_004955469:6,263,271...6,277,767 		JBrowse link
G Fkbp4 FKBP prolyl isomerase 4 enables ISO (PMID:11350175) UniProt PMID:11350175 NCBI chrNW_004955429:18,334,939...18,344,530
Ensembl chrNW_004955429:18,334,939...18,344,530 		JBrowse link
G Fkbp5 FKBP prolyl isomerase 5 enables ISO (PMID:11350175) UniProt PMID:11350175 NCBI chrNW_004955437:3,445,515...3,548,874
Ensembl chrNW_004955437:3,447,075...3,548,564 		JBrowse link
G Fkbp6 FKBP prolyl isomerase family member 6 (inactive) NOT|enables ISO (PMID:22902560) UniProt PMID:22902560 NCBI chrNW_004955456:14,291,445...14,318,310
Ensembl chrNW_004955456:14,291,260...14,318,310 		JBrowse link
G Nktr natural killer cell triggering receptor enables ISO (PMID:20676357) UniProt PMID:20676357 NCBI chrNW_004955420:28,148,040...28,193,734
Ensembl chrNW_004955420:28,150,386...28,193,735 		JBrowse link
G Pin1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 enables ISO (PMID:20956805)
(PMID:19122240), (PMID:26942675), (PMID:29686383)
(PMID:16554819), (PMID:17548053), (PMID:29686383)		 Reactome
UniProt		 PMID:16554819 PMID:17548053 PMID:19122240 PMID:20956805 PMID:26942675 More... NCBI chrNW_004955495:1,250,557...1,261,617
Ensembl chrNW_004955495:1,250,453...1,266,235 		JBrowse link
G Ppia peptidylprolyl isomerase A enables ISO (PMID:2001362), (PMID:21245143), (PMID:21593166), (PMID:25678563)
(PMID:24429998)
(PMID:14993672), (PMID:20676357)		 UniProt PMID:2001362 PMID:14993672 PMID:20676357 PMID:21245143 PMID:21593166 More... NCBI chrNW_004955456:7,381,923...7,383,203 JBrowse link
G Ppib peptidylprolyl isomerase B enables ISO (PMID:20676357) UniProt PMID:20676357 NCBI chrNW_004955450:11,241,279...11,246,628
Ensembl chrNW_004955450:11,241,279...11,249,056 		JBrowse link
G Ppic peptidylprolyl isomerase C enables ISO (PMID:20676357)
(PMID:1652374)		 UniProt PMID:1652374 PMID:20676357 NCBI chrNW_004955521:1,138,779...1,143,345
Ensembl chrNW_004955521:1,138,779...1,143,356 		JBrowse link
G Ppid peptidylprolyl isomerase D enables ISO (PMID:11350175), (PMID:20676357) RGD
UniProt		 PMID:11350175 PMID:12077116 PMID:20676357 RGD:625503 NCBI chrNW_004955471:12,309,224...12,323,198
Ensembl chrNW_004955471:12,305,236...12,323,198 		JBrowse link
G Ppie peptidylprolyl isomerase E enables ISO (PMID:18258190), (PMID:20676357) UniProt PMID:18258190 PMID:20676357 NCBI chrNW_004955452:17,242,255...17,256,776
Ensembl chrNW_004955452:17,242,286...17,254,860 		JBrowse link
G Ppif peptidylprolyl isomerase F enables ISO (PMID:20676357) RGD
UniProt		 PMID:1599421 PMID:15233627 PMID:20676357 RGD:2303985 RGD:729430 NCBI chrNW_004955437:13,295,766...13,301,918
Ensembl chrNW_004955437:13,295,663...13,302,175 		JBrowse link
G Ppig peptidylprolyl isomerase G enables ISO (PMID:20676357) RGD
UniProt		 PMID:9525923 PMID:20676357 RGD:633708 NCBI chrNW_004955449:4,915,747...4,958,456
Ensembl chrNW_004955449:4,915,753...4,958,220 		JBrowse link
G Ppih peptidylprolyl isomerase H enables ISO (PMID:20676357), (PMID:9570313) UniProt PMID:9570313 PMID:20676357 NCBI chrNW_004955537:2,211,566...2,229,444
Ensembl chrNW_004955537:2,211,410...2,230,452 		JBrowse link
G Ppil1 peptidylprolyl isomerase like 1 enables ISO (PMID:16595688) UniProt PMID:16595688 NCBI chrNW_004955437:6,131,013...6,143,474
Ensembl chrNW_004955437:6,131,013...6,143,529 		JBrowse link
G Ppil2 peptidylprolyl isomerase like 2 NOT|enables ISO (PMID:20676357) UniProt PMID:20676357 NCBI chrNW_004955442:17,426,154...17,449,079
Ensembl chrNW_004955442:17,425,231...17,449,832 		JBrowse link
G Ppil6 peptidylprolyl isomerase like 6 NOT|enables ISO (PMID:20676357) UniProt PMID:20676357 NCBI chrNW_004955411:34,449,508...34,481,370
Ensembl chrNW_004955411:34,452,864...34,481,366 		JBrowse link
G Ppwd1 peptidylprolyl isomerase domain and WD repeat containing 1 enables ISO (PMID:20676357) UniProt PMID:20676357 NCBI chrNW_004955446:3,511,152...3,531,584
Ensembl chrNW_004955446:3,510,797...3,531,855 		JBrowse link
G Ranbp2 RAN binding protein 2 NOT|enables ISO (PMID:20676357) UniProt PMID:20676357 NCBI chrNW_004955470:12,180,426...12,247,737
Ensembl chrNW_004955470:12,180,544...12,249,555 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 14366
    catalytic activity 3755
      catalytic activity, acting on a protein 1637
        peptidyl-prolyl cis-trans isomerase activity 23
          RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity + 0
Path 2
Term Annotations click to browse term
  molecular_function 14366
    catalytic activity 3755
      isomerase activity 107
        cis-trans isomerase activity 25
          peptidyl-prolyl cis-trans isomerase activity 23
            RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity + 0
paths to the root