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ONTOLOGY REPORT - ANNOTATIONS

Term:RNA helicase activity
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Accession:GO:0003724 term browser browse the term
Definition:Unwinding of an RNA helix, driven by ATP hydrolysis.
Synonyms:exact_synonym: ATP-dependent RNA helicase activity
 alt_id: GO:0004004
 xref: EC:3.6.4.13;   MetaCyc:RXN-11109;   Reactome:R-HSA-9770129 "Formation of the Spliceosomal A complex";   Reactome:R-HSA-9770131 "Formation of the Spliceosomal B* complex";   Reactome:R-HSA-9770141 "Formation of the Spliceosomal C* complex";   Reactome:R-HSA-9770142 "Formation of the Spliceosomal B complex";   Reactome:R-HSA-9770145 "Formation of the Spliceosomal Bact complex";   reactome:R-HSA-72647 "Cap-bound mRNA is activated by helicases"

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RNA helicase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DDX1 DEAD-box helicase 1 enables IEA InterPro
Ensembl
UniProt		 GO_REF:0000002 GO_REF:0000003 GO_REF:0000107 NCBI chr14:92,007,446...92,045,414
Ensembl chr14:92,007,036...92,045,190 		JBrowse link
G DDX10 DEAD-box helicase 10 enables IEA InterPro
UniProt		 GO_REF:0000002 GO_REF:0000003 NCBI chr 1:100,089,094...100,369,032
Ensembl chr 1:100,089,153...100,357,309 		JBrowse link
G DDX17 DEAD-box helicase 17 enables IEA InterPro
UniProt		 GO_REF:0000002 GO_REF:0000003 NCBI chr19:21,145,576...21,167,091
Ensembl chr19:21,145,417...21,167,543 		JBrowse link
G DDX18 DEAD-box helicase 18 enables IEA InterPro
UniProt		 GO_REF:0000002 GO_REF:0000003 NCBI chr10:12,455,877...12,473,670
Ensembl chr10:12,457,543...12,473,655 		JBrowse link
G DDX20 DEAD-box helicase 20 enables IEA InterPro
UniProt		 GO_REF:0000002 GO_REF:0000003 NCBI chr20:21,842,398...21,869,247
Ensembl chr20:21,839,223...21,853,601 		JBrowse link
G DDX21 DExD-box helicase 21 enables IEA UniProt
TreeGrafter		 GO_REF:0000003 GO_REF:0000118 NCBI chr 9:62,339,614...62,370,032 JBrowse link
G DDX23 DEAD-box helicase 23 enables IEA UniProt
InterPro		 GO_REF:0000002 GO_REF:0000003 NCBI chr11:45,071,884...45,092,287
Ensembl chr11:45,071,611...45,092,646 		JBrowse link
G DDX24 DEAD-box helicase 24 enables IEA UniProt
InterPro		 GO_REF:0000002 GO_REF:0000003 NCBI chr24:71,808,721...71,838,268
Ensembl chr24:71,808,995...71,838,262 		JBrowse link
G DDX25 DEAD-box helicase 25 enables ISO
IEA		 RGD
InterPro
UniProt
Ensembl		 PMID:10608860 GO_REF:0000002 GO_REF:0000003 GO_REF:0000107 RGD:68232 NCBI chr 1:117,035,171...117,053,726
Ensembl chr 1:117,035,310...117,053,494 		JBrowse link
G DDX27 DEAD-box helicase 27 enables IEA UniProt
TreeGrafter
InterPro		 GO_REF:0000002 GO_REF:0000003 GO_REF:0000118 NCBI chr 2:14,741,882...14,766,900
Ensembl chr 2:14,742,113...14,766,933 		JBrowse link
G DDX28 DEAD-box helicase 28 enables IEA UniProt
TreeGrafter
InterPro		 GO_REF:0000002 GO_REF:0000003 GO_REF:0000118 NCBI chr 5:59,412,602...59,415,170
Ensembl chr 5:59,413,265...59,414,905 		JBrowse link
G DDX31 DEAD-box helicase 31 enables IEA UniProt
InterPro		 GO_REF:0000002 GO_REF:0000003 NCBI chr12:5,468,127...5,545,610
Ensembl chr12:5,468,412...5,549,120 		JBrowse link
G DDX39A DExD-box helicase 39A enables IEA InterPro
UniProt		 GO_REF:0000002 GO_REF:0000003 NCBI chr 6:13,054,803...13,065,154
Ensembl chr 6:13,052,105...13,065,153 		JBrowse link
G DDX39B DExD-box helicase 39B enables IEA InterPro
Ensembl
UniProt		 GO_REF:0000002 GO_REF:0000003 GO_REF:0000107 NCBI chr17:40,445,258...40,457,379
Ensembl chr17:40,447,061...40,456,826 		JBrowse link
G DDX3X DEAD-box helicase 3 X-linked enables IEA InterPro
UniProt		 GO_REF:0000002 GO_REF:0000003 NCBI chr  X:38,513,251...38,539,982
Ensembl chr  Y:689,380...706,092 		JBrowse link
G DDX3X DEAD-box helicase 3 X-linked enables IEA UniProt
Ensembl
InterPro		 GO_REF:0000002 GO_REF:0000003 GO_REF:0000107 Ensembl chr  X:38,512,983...38,525,055 JBrowse link
G DDX4 DEAD-box helicase 4 enables IEA InterPro
UniProt		 GO_REF:0000002 GO_REF:0000003 NCBI chr 4:51,984,753...52,058,425
Ensembl chr 4:51,986,338...52,057,813 		JBrowse link
G DDX41 DEAD-box helicase 41 enables IEA InterPro
Ensembl
UniProt		 GO_REF:0000002 GO_REF:0000003 GO_REF:0000107 NCBI chr23:79,522,265...79,528,628
Ensembl chr23:79,522,479...79,527,570 		JBrowse link
G DDX42 DEAD-box helicase 42 enables IEA Ensembl GO_REF:0000107 NCBI chr16:57,470,095...57,517,056
Ensembl chr16:57,471,015...57,504,239 		JBrowse link
G DDX43 DEAD-box helicase 43 enables IEA InterPro
UniProt		 GO_REF:0000002 GO_REF:0000003 NCBI chr17:1,726,285...1,752,561
Ensembl chr17:1,727,429...1,752,110 		JBrowse link
G DDX47 DEAD-box helicase 47 enables IEA InterPro
TreeGrafter
UniProt		 GO_REF:0000002 GO_REF:0000003 GO_REF:0000118 NCBI chr11:12,716,375...12,734,494
Ensembl chr11:12,716,290...12,734,061 		JBrowse link
G DDX49 DEAD-box helicase 49 enables IEA UniProt
Ensembl
TreeGrafter
InterPro		 GO_REF:0000002 GO_REF:0000003 GO_REF:0000107 GO_REF:0000118 NCBI chr 6:17,376,050...17,384,625
Ensembl chr 6:17,376,273...17,384,663 		JBrowse link
G DDX5 DEAD-box helicase 5 enables ISO
IEA		 RGD
InterPro
Ensembl
UniProt		 PMID:7525583 GO_REF:0000002 GO_REF:0000003 GO_REF:0000107 RGD:5128519 NCBI chr16:56,766,669...56,773,767
Ensembl chr16:56,767,186...56,773,464 		JBrowse link
G DDX50 DExD-box helicase 50 enables IEA UniProt
TreeGrafter		 GO_REF:0000003 GO_REF:0000118 NCBI chr 9:62,378,977...62,424,108
Ensembl chr 9:62,377,491...62,424,006 		JBrowse link
G DDX52 DExD-box helicase 52 enables IEA UniProt
TreeGrafter
InterPro		 GO_REF:0000002 GO_REF:0000003 GO_REF:0000118 NCBI chr16:30,138,075...30,168,803
Ensembl chr16:30,138,084...30,170,332 		JBrowse link
G DDX53 DEAD-box helicase 53 enables IEA UniProt GO_REF:0000003 NCBI chr  X:21,480,981...21,483,389
Ensembl chr  X:21,481,264...21,483,162 		JBrowse link
G DDX54 DEAD-box helicase 54 enables IEA UniProt
TreeGrafter
Ensembl
InterPro		 GO_REF:0000002 GO_REF:0000003 GO_REF:0000107 GO_REF:0000118 NCBI chr11:108,407,623...108,437,188
Ensembl chr11:108,404,719...108,437,168 		JBrowse link
G DDX55 DEAD-box helicase 55 enables IEA UniProt
InterPro		 GO_REF:0000002 GO_REF:0000003 NCBI chr11:118,930,642...118,949,331
Ensembl chr11:118,930,683...118,948,814 		JBrowse link
G DDX56 DEAD-box helicase 56 enables IEA InterPro
TreeGrafter
UniProt		 GO_REF:0000002 GO_REF:0000003 GO_REF:0000118 NCBI chr21:14,096,653...14,112,132
Ensembl chr21:14,104,060...14,114,645 		JBrowse link
G DDX59 DEAD-box helicase 59 enables IEA InterPro
TreeGrafter
UniProt		 GO_REF:0000002 GO_REF:0000003 GO_REF:0000118 NCBI chr25:28,730,217...28,755,879
Ensembl chr25:28,730,718...28,756,034 		JBrowse link
G DDX6 DEAD-box helicase 6 enables IEA UniProt
InterPro		 GO_REF:0000002 GO_REF:0000003 NCBI chr 1:110,128,450...110,172,383
Ensembl chr 1:110,135,471...110,167,463 		JBrowse link
G DHX15 DEAH-box helicase 15 enables IEA InterPro
Ensembl
UniProt		 GO_REF:0000002 GO_REF:0000003 GO_REF:0000107 NCBI chr27:25,775,156...25,832,309
Ensembl chr27:25,775,160...25,831,860 		JBrowse link
G DHX16 DEAH-box helicase 16 enables IEA UniProt GO_REF:0000003 NCBI chr17:41,780,965...41,801,310
Ensembl chr17:41,780,987...41,801,219 		JBrowse link
G DHX29 DExH-box helicase 29 enables IEA UniProt
InterPro		 GO_REF:0000002 GO_REF:0000003 GO_REF:0000104 NCBI chr 4:51,491,356...51,543,889
Ensembl chr 4:51,491,598...51,543,774 		JBrowse link
G DHX30 DExH-box helicase 30 enables IEA UniProt
Ensembl
TreeGrafter		 GO_REF:0000003 GO_REF:0000107 GO_REF:0000118 NCBI chr22:9,191,527...9,239,445
Ensembl chr22:9,206,175...9,239,372 		JBrowse link
G DHX33 DEAH-box helicase 33 enables IEA UniProt GO_REF:0000003 Ensembl chr16:4,855,652...4,879,902 JBrowse link
G DHX35 DEAH-box helicase 35 enables IEA UniProt GO_REF:0000003 NCBI chr 2:24,710,517...24,790,687
Ensembl chr 2:24,709,054...24,789,520 		JBrowse link
G DHX36 DEAH-box helicase 36 enables IEA UniProt
Ensembl
TreeGrafter		 GO_REF:0000003 GO_REF:0000107 GO_REF:0000118 NCBI chr15:36,387,242...36,438,133
Ensembl chr15:36,387,228...36,437,606 		JBrowse link
G DHX38 DEAH-box helicase 38 enables IEA UniProt GO_REF:0000003 NCBI chr 5:55,243,934...55,264,084
Ensembl chr 5:55,243,911...55,263,706 		JBrowse link
G DHX40 DEAH-box helicase 40 enables IEA UniProt GO_REF:0000003 NCBI chr16:33,838,787...33,880,134
Ensembl chr16:33,838,031...33,880,100 		JBrowse link
G DHX57 DExH-box helicase 57 enables IEA UniProt GO_REF:0000003 NCBI chr14:68,509,127...68,583,741
Ensembl chr14:68,509,414...68,584,276 		JBrowse link
G DHX58 DExH-box helicase 58 enables IEA UniProt
Ensembl		 GO_REF:0000003 GO_REF:0000107 NCBI chr16:64,154,832...64,166,480
Ensembl chr16:64,154,984...64,166,500 		JBrowse link
G DHX8 DEAH-box helicase 8 enables IEA InterPro
TreeGrafter
UniProt		 GO_REF:0000002 GO_REF:0000003 GO_REF:0000118 NCBI chr16:62,887,115...62,925,119
Ensembl chr16:62,887,594...62,925,061 		JBrowse link
G DHX9 DExH-box helicase 9 enables IEA UniProt
TreeGrafter
Ensembl		 GO_REF:0000003 GO_REF:0000107 GO_REF:0000118 NCBI chr25:46,485,602...46,534,046
Ensembl chr25:46,485,427...46,518,406 		JBrowse link
G EIF4A1 eukaryotic translation initiation factor 4A1 enables IEA InterPro
UniProt		 GO_REF:0000002 GO_REF:0000003 NCBI chr16:6,949,574...6,956,540
Ensembl chr16:6,949,628...6,956,026 		JBrowse link
G EIF4A2 eukaryotic translation initiation factor 4A2 enables IEA InterPro
UniProt		 GO_REF:0000002 GO_REF:0000003 NCBI chr15:81,075,073...81,081,412
Ensembl chr15:81,074,834...81,079,832 		JBrowse link
G EIF4A3 eukaryotic translation initiation factor 4A3 enables ISO (PMID:10523622) HGNC-UCL PMID:10523622 NCBI chr16:72,097,692...72,113,112 JBrowse link
G G3BP1 G3BP stress granule assembly factor 1 enables IEA Ensembl GO_REF:0000107 NCBI chr23:54,335,996...54,369,956
Ensembl chr23:54,336,113...54,368,674 		JBrowse link
G HELZ2 helicase with zinc finger 2 enables ISO (PMID:37602378) UniProt PMID:37602378 NCBI chr 2:632,572...647,618
Ensembl chr 2:633,042...647,613 		JBrowse link
G IFIH1 interferon induced with helicase C domain 1 enables IEA UniProt
Ensembl		 GO_REF:0000003 GO_REF:0000107 NCBI chr10:47,676,799...47,732,310
Ensembl chr10:47,676,920...47,732,264 		JBrowse link
G LOC103233154 ATP-dependent RNA helicase DDX19A enables IEA UniProt
InterPro		 GO_REF:0000002 GO_REF:0000003 NCBI chr 5:53,498,746...53,522,981
Ensembl chr 5:53,498,862...53,521,566 		JBrowse link
G LOC103233156 ATP-dependent RNA helicase DDX19B enables IEA InterPro
UniProt		 GO_REF:0000002 GO_REF:0000003 NCBI chr 5:53,438,552...53,480,623
Ensembl chr 5:53,443,037...53,481,987 		JBrowse link
G MOV10 Mov10 RNA helicase enables IEA UniProt GO_REF:0000003 NCBI chr20:20,939,052...20,966,843
Ensembl chr20:20,939,300...20,965,140 		JBrowse link
G MOV10L1 Mov10 like RNA helicase 1 enables ISO (PMID:25762440) UniProt PMID:25762440 NCBI chr19:32,586,652...32,653,563
Ensembl chr19:32,587,008...32,653,886 		JBrowse link
G MTREX Mtr4 exosome RNA helicase enables IEA InterPro
Ensembl		 GO_REF:0000002 GO_REF:0000107 NCBI chr 4:51,543,976...51,667,458
Ensembl chr 4:51,544,211...51,667,254 		JBrowse link
G RIGI RNA sensor RIG-I enables IEA UniProt
Ensembl		 GO_REF:0000003 GO_REF:0000107 NCBI chr12:47,729,040...47,800,995
Ensembl chr12:47,729,076...47,799,570 		JBrowse link
G SKIC2 SKI2 subunit of superkiller complex enables IEA InterPro GO_REF:0000002 NCBI chr17:40,052,166...40,063,304
Ensembl chr17:40,052,213...40,063,009 		JBrowse link
G SNRNP200 small nuclear ribonucleoprotein U5 subunit 200 enables IEA Ensembl GO_REF:0000107 NCBI chr14:693,873...724,226
Ensembl chr14:694,126...724,208 		JBrowse link
G SUPV3L1 Suv3 like RNA helicase enables IEA UniProt
Ensembl
InterPro		 GO_REF:0000002 GO_REF:0000003 GO_REF:0000107 NCBI chr 9:62,111,702...62,141,092
Ensembl chr 9:62,111,648...62,141,045 		JBrowse link
G UPF1 UPF1 RNA helicase and ATPase enables IEA InterPro
Ensembl
TreeGrafter		 GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 NCBI chr 6:17,291,189...17,328,768
Ensembl chr 6:17,291,175...17,330,193 		JBrowse link
G YTHDC2 YTH N6-methyladenosine RNA binding protein C2 enables IEA UniProt GO_REF:0000003 NCBI chr23:16,800,515...16,880,983
Ensembl chr23:16,800,558...16,880,952 		JBrowse link
3'-5' RNA helicase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AQR aquarius intron-binding spliceosomal factor enables IEA Ensembl GO_REF:0000107 NCBI chr26:47,927,167...48,036,764
Ensembl chr26:47,927,137...48,036,478 		JBrowse link
G DHX38 DEAH-box helicase 38 enables IEA TreeGrafter GO_REF:0000118 NCBI chr 5:55,243,934...55,264,084
Ensembl chr 5:55,243,911...55,263,706 		JBrowse link
G DHX40 DEAH-box helicase 40 enables IEA TreeGrafter GO_REF:0000118 NCBI chr16:33,838,787...33,880,134
Ensembl chr16:33,838,031...33,880,100 		JBrowse link
G DHX9 DExH-box helicase 9 enables IEA Ensembl GO_REF:0000107 NCBI chr25:46,485,602...46,534,046
Ensembl chr25:46,485,427...46,518,406 		JBrowse link
G SKIC2 SKI2 subunit of superkiller complex enables IEA Ensembl GO_REF:0000107 NCBI chr17:40,052,166...40,063,304
Ensembl chr17:40,052,213...40,063,009 		JBrowse link
G SUPV3L1 Suv3 like RNA helicase enables IEA Ensembl GO_REF:0000107 NCBI chr 9:62,111,702...62,141,092
Ensembl chr 9:62,111,648...62,141,045 		JBrowse link
G YTHDC2 YTH N6-methyladenosine RNA binding protein C2 enables IEA Ensembl GO_REF:0000107 NCBI chr23:16,800,515...16,880,983
Ensembl chr23:16,800,558...16,880,952 		JBrowse link
5'-3' RNA helicase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IGHMBP2 immunoglobulin mu DNA binding protein 2 enables IEA Ensembl GO_REF:0000107 NCBI chr 1:5,619,138...5,655,033
Ensembl chr 1:5,619,425...5,655,737 		JBrowse link
G MOV10 Mov10 RNA helicase enables IEA InterPro
Ensembl		 GO_REF:0000002 GO_REF:0000107 NCBI chr20:20,939,052...20,966,843
Ensembl chr20:20,939,300...20,965,140 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 19851
    ATP-dependent activity 579
      helicase activity 147
        RNA helicase activity 63
          3'-5' RNA helicase activity 7
          5'-3' RNA helicase activity 2
Path 2
Term Annotations click to browse term
  molecular_function 19851
    catalytic activity 5545
      isomerase activity 435
        macromolecular conformation isomerase activity 267
          nucleic acid conformation isomerase activity 159
            helicase activity 147
              RNA helicase activity 63
                3'-5' RNA helicase activity 7
                5'-3' RNA helicase activity 2
paths to the root