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ONTOLOGY REPORT - ANNOTATIONS

Term:RNA helicase activity
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Accession:GO:0003724 term browser browse the term
Definition:Unwinding of an RNA helix, driven by ATP hydrolysis.
Synonyms:exact_synonym: ATP-dependent RNA helicase activity
 alt_id: GO:0004004
 xref: EC:3.6.4.13;   MetaCyc:RXN-11109;   Reactome:R-HSA-9770129 "Formation of the Spliceosomal A complex";   Reactome:R-HSA-9770131 "Formation of the Spliceosomal B* complex";   Reactome:R-HSA-9770141 "Formation of the Spliceosomal C* complex";   Reactome:R-HSA-9770142 "Formation of the Spliceosomal B complex";   Reactome:R-HSA-9770145 "Formation of the Spliceosomal Bact complex";   reactome:R-HSA-72647 "Cap-bound mRNA is activated by helicases"


show annotations for term's descendants           Sort by:
RNA helicase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ddx1 DEAD-box helicase 1 enables ISO
ISS		 (PMID:12183465), (PMID:18710941)
GO_REF:0000024		 RGD
UniProt		 PMID:12183465 PMID:18710941 GO_REF:0000024 NCBI chr 6:35,996,469...36,027,340
Ensembl chr 6:35,996,469...36,027,365 		JBrowse link
G Ddx10 DEAD-box helicase 10 enables IEA GO_REF:0000003 UniProt GO_REF:0000003 NCBI chr 8:53,488,656...53,643,373
Ensembl chr 8:53,488,656...53,643,373 		JBrowse link
G Ddx17 DEAD-box helicase 17 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 7:111,091,127...111,109,353
Ensembl chr 7:111,089,445...111,109,193 		JBrowse link
G Ddx19a DEAD-box helicase 19A enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr19:38,942,497...38,962,853
Ensembl chr19:38,942,496...38,962,854 		JBrowse link
G Ddx19b DEAD-box helicase 19B enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr19:38,968,215...38,998,907
Ensembl chr19:38,968,215...38,997,259 		JBrowse link
G Ddx20 DEAD-box helicase 20 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 2:193,158,761...193,168,484
Ensembl chr 2:193,158,823...193,166,774 		JBrowse link
G Ddx21 DExD-box helicase 21 enables ISO
IBA
ISS		 (PMID:25470060), (PMID:28790157), (PMID:9461305)
GO_REF:0000033
GO_REF:0000024		 RGD
GO_Central
UniProt		 PMID:9461305 PMID:25470060 PMID:28790157 GO_REF:0000024 GO_REF:0000033 NCBI chr20:30,534,319...30,554,513
Ensembl chr20:30,534,319...30,554,543 		JBrowse link
G Ddx24 DEAD-box helicase 24 enables IEA GO_REF:0000003
GO_REF:0000002		 UniProt
InterPro		 GO_REF:0000002 GO_REF:0000003 NCBI chr 6:122,564,767...122,582,032
Ensembl chr 6:122,564,767...122,581,927 		JBrowse link
G Ddx25 DEAD-box helicase 25 enables IDA
ISO
IBA
IEA
ISS		 (PMID:10608860)
GO_REF:0000033
GO_REF:0000002
(MGI:1351064|PMID:10608860)
GO_REF:0000024		 RGD
GO_Central
InterPro
UniProt		 PMID:10608860 PMID:10608860 GO_REF:0000002 GO_REF:0000024 GO_REF:0000033 MGI:1351064, RGD:68232 NCBI chr 8:33,894,224...33,910,377
Ensembl chr 8:33,894,232...33,921,764 		JBrowse link
G Ddx27 DEAD-box helicase 27 enables IEA GO_REF:0000003
GO_REF:0000002		 UniProt
InterPro		 GO_REF:0000002 GO_REF:0000003 NCBI chr 3:155,744,182...155,763,380
Ensembl chr 3:155,744,150...155,763,372 		JBrowse link
G Ddx28 DEAD-box helicase 28 enables IEA GO_REF:0000003 UniProt GO_REF:0000003 NCBI chr19:33,909,799...33,911,729
Ensembl chr19:33,909,801...33,911,742 		JBrowse link
G Ddx3 DEAD-box helicase 3 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr13:98,520,538...98,523,707
Ensembl chr13:98,520,201...98,524,176 		JBrowse link
G Ddx31 DEAD-box helicase 31 enables IEA GO_REF:0000003 UniProt GO_REF:0000003 NCBI chr 3:12,172,829...12,238,392
Ensembl chr 3:12,172,836...12,238,873 		JBrowse link
G Ddx39a DExD-box helicase 39A enables IEA
IBA		 GO_REF:0000002
GO_REF:0000033		 InterPro
GO_Central		 GO_REF:0000002 GO_REF:0000033 NCBI chr19:24,418,743...24,427,422
Ensembl chr19:24,418,114...24,426,954 		JBrowse link
G Ddx39b DExD-box helicase 39B enables ISO
IBA
IEA		 (PMID:17562711), (PMID:18593880)
GO_REF:0000033
GO_REF:0000107
GO_REF:0000002
GO_REF:0000003		 RGD
GO_Central
Ensembl
InterPro
UniProt		 PMID:17562711 PMID:18593880 GO_REF:0000002 GO_REF:0000003 GO_REF:0000033 GO_REF:0000107 NCBI chr20:3,547,702...3,585,064
Ensembl chr20:3,572,056...3,584,996 		JBrowse link
G Ddx3x DEAD-box helicase 3, X-linked enables ISO
IBA		 (PMID:21589879), (PMID:31575075)
GO_REF:0000033		 RGD
GO_Central		 PMID:21589879 PMID:31575075 GO_REF:0000033 NCBI chr  X:9,479,532...9,493,169
Ensembl chr  X:9,479,532...9,493,168 		JBrowse link
G Ddx3y DEAD box helicase 3, Y-linked enables IEA
IBA		 GO_REF:0000002
GO_REF:0000033		 InterPro
GO_Central		 GO_REF:0000002 GO_REF:0000033 NCBI chr  Y:1,115,095...1,135,754
Ensembl chr  Y:1,116,309...1,135,706 		JBrowse link
G Ddx4 DEAD-box helicase 4 enables IEA
IBA		 GO_REF:0000003
GO_REF:0000033
GO_REF:0000002		 UniProt
GO_Central
InterPro		 GO_REF:0000002 GO_REF:0000003 GO_REF:0000033 NCBI chr 2:44,227,946...44,282,867
Ensembl chr 2:44,227,946...44,282,723 		JBrowse link
G Ddx41 DEAD-box helicase 41 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr17:9,102,926...9,108,415
Ensembl chr17:9,103,010...9,108,415 		JBrowse link
G Ddx41l1 DEAD-box helicase 41 like 1 enables IEA
IBA		 GO_REF:0000002
GO_REF:0000033		 InterPro
GO_Central		 GO_REF:0000002 GO_REF:0000033 NCBI chr 6:107,185,923...107,187,961
Ensembl chr 6:107,186,096...107,187,961 		JBrowse link
G Ddx42 DEAD-box helicase 42 enables ISO (PMID:16397294) RGD PMID:16397294 NCBI chr10:91,148,926...91,180,940
Ensembl chr10:91,148,254...91,180,939 		JBrowse link
G Ddx43 DEAD-box helicase 43 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 8:79,255,001...79,284,468
Ensembl chr 8:79,255,655...79,284,453 		JBrowse link
G Ddx46 DEAD-box helicase 46 enables IEA GO_REF:0000003
GO_REF:0000002		 UniProt
InterPro		 GO_REF:0000002 GO_REF:0000003 NCBI chr17:8,942,070...8,988,440
Ensembl chr17:8,944,454...8,988,439 		JBrowse link
G Ddx47 DEAD-box helicase 47 enables IEA GO_REF:0000003
GO_REF:0000002		 UniProt
InterPro		 GO_REF:0000002 GO_REF:0000003 NCBI chr 4:167,845,652...167,858,115
Ensembl chr 4:167,845,640...167,859,115 		JBrowse link
G Ddx49 DEAD-box helicase 49 enables IEA GO_REF:0000003
GO_REF:0000002		 UniProt
InterPro		 GO_REF:0000002 GO_REF:0000003 NCBI chr16:19,125,388...19,133,042
Ensembl chr16:19,125,384...19,133,616 		JBrowse link
G Ddx5 DEAD-box helicase 5 enables IDA
IBA
ISO		 GO_REF:0000033
(PMID:21343338)		 GO_Central
RGD		 PMID:21343338 PMID:7525583 GO_REF:0000033, RGD:5128519 NCBI chr10:91,723,508...91,732,210
Ensembl chr10:91,723,508...91,732,283 		JBrowse link
G Ddx50 DExD-box helicase 50 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr20:30,561,623...30,591,324
Ensembl chr20:30,560,544...30,591,152 		JBrowse link
G Ddx52 DExD-box helicase 52 enables NAS
IEA		 GO_REF:0000002 InterPro
RGD		 PMID:9154839 GO_REF:0000002, RGD:704356 NCBI chr10:68,824,594...68,847,400
Ensembl chr10:68,824,645...68,848,266 		JBrowse link
G Ddx54 DEAD-box helicase 54 enables ISO (PMID:12466272) RGD PMID:12466272 NCBI chr12:35,934,713...35,949,956
Ensembl chr12:35,934,716...35,972,523 		JBrowse link
G Ddx55 DEAD-box helicase 55 enables IEA GO_REF:0000003
GO_REF:0000002		 UniProt
InterPro		 GO_REF:0000002 GO_REF:0000003 NCBI chr12:32,034,462...32,050,218
Ensembl chr12:32,034,462...32,050,219 		JBrowse link
G Ddx56 DEAD-box helicase 56 enables IEA GO_REF:0000003 UniProt GO_REF:0000003 NCBI chr14:81,112,008...81,122,331
Ensembl chr14:81,112,012...81,122,333 		JBrowse link
G Ddx59 DEAD-box helicase 59 enables IEA
IBA		 GO_REF:0000003
GO_REF:0000033
GO_REF:0000002		 UniProt
GO_Central
InterPro		 GO_REF:0000002 GO_REF:0000003 GO_REF:0000033 NCBI chr13:47,876,258...47,901,214
Ensembl chr13:47,876,261...47,901,214 		JBrowse link
G Ddx6 DEAD-box helicase 6 enables IEA GO_REF:0000003
GO_REF:0000002		 UniProt
InterPro		 GO_REF:0000002 GO_REF:0000003 NCBI chr 8:44,931,127...44,967,773
Ensembl chr 8:44,931,974...44,964,405 		JBrowse link
G Dhx15 DEAH-box helicase 15 enables ISO (PMID:32179686) RGD PMID:32179686 NCBI chr14:58,787,147...58,825,083
Ensembl chr14:58,787,127...58,825,088 		JBrowse link
G Dhx16 DEAH-box helicase 16 enables IEA GO_REF:0000003 UniProt GO_REF:0000003 NCBI chr20:2,862,000...2,874,991
Ensembl chr20:2,862,000...2,874,948 		JBrowse link
G Dhx29 DExH-box helicase 29 enables IEA GO_REF:0000003
GO_REF:0000104		 UniProt GO_REF:0000003 GO_REF:0000104 NCBI chr 2:44,560,653...44,611,450
Ensembl chr 2:44,560,714...44,611,445 		JBrowse link
G Dhx30 DExH-box helicase 30 enables IEA
ISO
IBA
ISS		 GO_REF:0000003
(PMID:25219788)
GO_REF:0000033
GO_REF:0000107
(MGI:5616495|PMID:25219788)
GO_REF:0000024
(PMID:29100085)		 UniProt
RGD
GO_Central
Ensembl		 PMID:25219788 PMID:29100085 GO_REF:0000003 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 MGI:5616495 NCBI chr 8:110,064,751...110,096,954
Ensembl chr 8:110,064,752...110,097,381 		JBrowse link
G Dhx33 DEAH-box helicase 33 enables IEA GO_REF:0000003 UniProt GO_REF:0000003 NCBI chr10:55,708,102...55,724,618
Ensembl chr10:55,705,756...55,724,567 		JBrowse link
G Dhx35 DEAH-box helicase 35 enables IEA GO_REF:0000003 UniProt GO_REF:0000003 NCBI chr 3:147,450,178...147,507,473
Ensembl chr 3:147,450,163...147,507,451 		JBrowse link
G Dhx36 DEAH-box helicase 36 enables ISS
IBA
ISO		 GO_REF:0000024
GO_REF:0000033
(PMID:14731398), (PMID:18842585), (PMID:21846770)		 UniProt
GO_Central
RGD		 PMID:14731398 PMID:18842585 PMID:21846770 GO_REF:0000024 GO_REF:0000033 NCBI chr 2:146,856,469...146,894,577
Ensembl chr 2:146,856,469...146,894,572 		JBrowse link
G Dhx40 DEAH-box helicase 40 enables IEA GO_REF:0000003 UniProt GO_REF:0000003 NCBI chr10:71,584,546...71,621,479
Ensembl chr10:71,583,716...71,621,445 		JBrowse link
G Dhx58 DEXH-box helicase 58 enables ISO (PMID:19211564) RGD PMID:19211564 NCBI chr10:85,620,352...85,631,776
Ensembl chr10:85,620,357...85,631,525 		JBrowse link
G Dhx8 DEAH-box helicase 8 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr10:86,667,641...86,704,198
Ensembl chr10:86,667,834...86,705,137 		JBrowse link
G Dhx9 DExH-box helicase 9 enables ISO
IBA		 (PMID:28221134)
GO_REF:0000033		 RGD
GO_Central		 PMID:28221134 GO_REF:0000033 NCBI chr13:65,602,322...65,639,098
Ensembl chr13:65,602,323...65,639,069 		JBrowse link
G Eif4a1 eukaryotic translation initiation factor 4A1 enables IEA GO_REF:0000003
GO_REF:0000002		 UniProt
InterPro		 GO_REF:0000002 GO_REF:0000003 NCBI chr10:54,384,345...54,389,855
Ensembl chr10:54,384,347...54,389,858 		JBrowse link
G Eif4a1-ps8 eukaryotic translation initiation factor 4A1, pseudogene 8 enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 6:76,623,866...76,625,179
Ensembl chr 6:76,623,866...76,625,392 		JBrowse link
G Eif4a2 eukaryotic translation initiation factor 4A2 enables IEA GO_REF:0000003
GO_REF:0000002		 UniProt
InterPro		 GO_REF:0000002 GO_REF:0000003 NCBI chr11:77,764,126...77,770,810
Ensembl chr11:77,764,124...77,770,781 		JBrowse link
G Eif4a3 eukaryotic translation initiation factor 4A3 enables ISO
IBA
IEA		 (PMID:10523622)
GO_REF:0000033
GO_REF:0000002		 RGD
GO_Central
InterPro		 PMID:10523622 GO_REF:0000002 GO_REF:0000033 NCBI chr10:104,549,038...104,559,032
Ensembl chr10:104,549,038...104,559,057 		JBrowse link
G ENSRNOG00000066881 enables IEA GO_REF:0000002 InterPro GO_REF:0000002 Ensembl chr13:2,852,897...2,854,568 JBrowse link
G ENSRNOG00000068837 enables IEA GO_REF:0000002 InterPro GO_REF:0000002 Ensembl chr 1:4,760,023...4,760,893 JBrowse link
G ENSRNOG00000069412 enables IEA GO_REF:0000002 InterPro GO_REF:0000002 Ensembl chr14:65,774,228...65,774,657 JBrowse link
G G3bp1 G3BP stress granule assembly factor 1 enables ISO (PMID:9889278) RGD PMID:9889278 NCBI chr10:39,586,864...39,620,268
Ensembl chr10:39,586,864...39,620,268 		JBrowse link
G Helz2 helicase with zinc finger 2 enables ISO (PMID:37602378) RGD PMID:37602378 NCBI chr 3:168,338,813...168,353,219
Ensembl chr 3:168,338,813...168,353,159 		JBrowse link
G Ifih1 interferon induced with helicase C domain 1 enables ISO (PMID:19211564) RGD PMID:19211564 NCBI chr 3:47,228,980...47,275,403
Ensembl chr 3:47,227,364...47,275,456 		JBrowse link
G LOC100912568 probable ATP-dependent RNA helicase DDX41-like enables IEA
IBA		 GO_REF:0000002
GO_REF:0000033		 InterPro
GO_Central		 GO_REF:0000002 GO_REF:0000033 NCBI chr 6:107,230,038...107,231,786
Ensembl chr 6:107,226,563...107,244,212 		JBrowse link
G Mov10l1 Mov10 like RNA helicase 1 enables ISO (MGI:5638960|PMID:25762440)
(PMID:25762440)		 RGD PMID:25762440 MGI:5638960 NCBI chr 7:120,070,171...120,135,406
Ensembl chr 7:120,070,135...120,134,765 		JBrowse link
G Mtrex Mtr4 exosome RNA helicase enables ISO
IBA		 (PMID:29844170), (PMID:29906447)
GO_REF:0000033		 RGD
GO_Central		 PMID:29844170 PMID:29906447 GO_REF:0000033 NCBI chr 2:44,500,326...44,560,624
Ensembl chr 2:44,461,444...44,560,627 		JBrowse link
G Rig1 RNA sensor RIG-1 enables ISO (PMID:19211564) RGD PMID:19211564 NCBI chr 5:55,321,351...55,369,947
Ensembl chr 5:55,321,235...55,370,819 		JBrowse link
G Skic2 SKI2 subunit of superkiller complex enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr20:3,982,494...3,993,261
Ensembl chr20:3,982,593...3,993,261 		JBrowse link
G Snrnp200 small nuclear ribonucleoprotein U5 subunit 200 enables IEA
IBA
ISO
ISS		 GO_REF:0000107
GO_REF:0000033
(PMID:23045696), (PMID:35241646)
GO_REF:0000024		 Ensembl
GO_Central
RGD
UniProt		 PMID:23045696 PMID:35241646 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr 3:114,428,854...114,458,194
Ensembl chr 3:114,428,854...114,458,182 		JBrowse link
G Supv3l1 Suv3 like RNA helicase enables ISO
IBA
ISS		 (PMID:19509288)
GO_REF:0000033
GO_REF:0000024		 RGD
GO_Central
UniProt		 PMID:19509288 GO_REF:0000024 GO_REF:0000033 NCBI chr20:30,378,542...30,399,076
Ensembl chr20:30,378,550...30,399,054 		JBrowse link
G Tdrd9 tudor domain containing 9 enables IEA GO_REF:0000003 UniProt GO_REF:0000003 NCBI chr 6:131,029,644...131,145,076
Ensembl chr 6:131,029,652...131,144,651 		JBrowse link
G Upf1 UPF1, RNA helicase and ATPase enables ISO
IBA		 (PMID:12554878), (PMID:21419344)
GO_REF:0000033		 RGD
GO_Central		 PMID:12554878 PMID:21419344 GO_REF:0000033 NCBI chr16:19,076,594...19,097,365
Ensembl chr16:19,076,322...19,096,568 		JBrowse link
3'-5' RNA helicase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aqr aquarius intron-binding spliceosomal factor enables ISO (PMID:25599396) RGD PMID:25599396 NCBI chr 3:100,874,987...100,945,026
Ensembl chr 3:100,874,987...100,945,044 		JBrowse link
G Dhx38 DEAH-box helicase 38 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr19:37,512,893...37,530,135
Ensembl chr19:37,512,891...37,530,140 		JBrowse link
G Dhx9 DExH-box helicase 9 enables ISO (PMID:1537828), (PMID:21561811) RGD PMID:1537828 PMID:21561811 NCBI chr13:65,602,322...65,639,098
Ensembl chr13:65,602,323...65,639,069 		JBrowse link
G Skic2 SKI2 subunit of superkiller complex enables ISO (PMID:35120588) RGD PMID:35120588 NCBI chr20:3,982,494...3,993,261
Ensembl chr20:3,982,593...3,993,261 		JBrowse link
G Supv3l1 Suv3 like RNA helicase enables IEA
ISS
ISO		 GO_REF:0000107
GO_REF:0000024
(PMID:15096047), (PMID:19509288), (PMID:35481630)		 Ensembl
UniProt
RGD		 PMID:15096047 PMID:19509288 PMID:35481630 GO_REF:0000024 GO_REF:0000107 NCBI chr20:30,378,542...30,399,076
Ensembl chr20:30,378,550...30,399,054 		JBrowse link
G Ythdc2 YTH N6-methyladenosine RNA binding protein C2 enables ISO (PMID:29033321)
(MGI:6113138|PMID:29360036)
(PMID:29360036)		 RGD PMID:29033321 PMID:29360036 MGI:6113138 NCBI chr18:37,266,559...37,331,681
Ensembl chr18:37,265,836...37,331,023 		JBrowse link
5'-3' RNA helicase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ighmbp2 immunoglobulin mu DNA binding protein 2 enables IEA
ISO
ISS		 GO_REF:0000107
(PMID:19158098)
GO_REF:0000024		 Ensembl
RGD
UniProt		 PMID:19158098 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:200,506,641...200,529,293
Ensembl chr 1:200,506,338...200,529,514 		JBrowse link
G Mov10 Mov10 RNA helicase enables ISO (PMID:24726324) RGD PMID:24726324 NCBI chr 2:192,292,041...192,315,142
Ensembl chr 2:192,293,470...192,315,083 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 20732
    ATP-dependent activity 628
      helicase activity 153
        RNA helicase activity 68
          3'-5' RNA helicase activity 6
          5'-3' RNA helicase activity 2
Path 2
Term Annotations click to browse term
  molecular_function 20732
    catalytic activity 6109
      catalytic activity, acting on a nucleic acid 633
        helicase activity 153
          RNA helicase activity 68
            3'-5' RNA helicase activity 6
            5'-3' RNA helicase activity 2
paths to the root