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ONTOLOGY REPORT - ANNOTATIONS

Term:DNA clamp loader activity
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Accession:GO:0003689 term browser browse the term
Definition:Facilitating the opening of the ring structure of the PCNA complex, or any of the related sliding clamp complexes, and their closing around the DNA duplex, driven by ATP hydrolysis.
Synonyms:exact_synonym: DNA clamp loading ATPase activity
 narrow_synonym: PCNA loading activity;   PCNA loading complex activity
 related_synonym: DNA-protein loading ATPase activity
 alt_id: GO:0033170
 xref: Reactome:R-HSA-174439 "Loading of PCNA - Sliding Clamp Formation on the C-strand of the telomere";   reactome:R-HSA-176264 "Recruitment of the Rad9-Hus1-Rad1 complex to DNA"


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DNA clamp loader activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CHTF18 chromosome transmission fidelity factor 18 enables
contributes_to		 IEA
IBA		 Ensembl
TreeGrafter
GO_Central		 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr 3:41,000,688...41,009,588
Ensembl chr 3:41,000,690...41,009,589 		JBrowse link
G DSCC1 DNA replication and sister chromatid cohesion 1 contributes_to
enables		 ISO
IEA		 (PMID:12930902) UniProtKB
Ensembl		 PMID:12930902 GO_REF:0000107 NCBI chr 4:19,161,063...19,180,002
Ensembl chr 4:19,161,226...19,178,568 		JBrowse link
G RAD17 RAD17 checkpoint clamp loader component enables
contributes_to		 IEA
IBA		 InterPro
GO_Central
TreeGrafter		 GO_REF:0000002 GO_REF:0000033 GO_REF:0000118 NCBI chr16:47,499,669...47,529,703
Ensembl chr16:47,499,669...47,529,702 		JBrowse link
G RFC1 replication factor C subunit 1 enables IEA InterPro
UniProt		 GO_REF:0000002 GO_REF:0000104 NCBI chr 8:30,552,369...30,635,932
Ensembl chr 8:30,552,400...30,635,867 		JBrowse link
G RFC2 replication factor C subunit 2 enables
contributes_to		 IEA
IBA		 Ensembl
TreeGrafter
GO_Central		 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr 3:11,373,489...11,392,690
Ensembl chr 3:11,373,492...11,392,695 		JBrowse link
G RFC3 replication factor C subunit 3 enables
contributes_to		 IEA
IBA		 Ensembl
TreeGrafter
GO_Central		 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr11:10,145,927...10,524,472
Ensembl chr11:10,146,531...10,165,172 		JBrowse link
G RFC4 replication factor C subunit 4 enables
contributes_to		 IEA
IBA		 Ensembl
TreeGrafter
GO_Central		 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr13:124,589,292...124,604,421
Ensembl chr13:124,589,295...124,604,426 		JBrowse link
G RFC5 replication factor C subunit 5 enables
contributes_to		 IEA
IBA		 Ensembl
TreeGrafter
GO_Central		 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr14:34,630,374...34,642,598
Ensembl chr14:34,629,951...34,642,585 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 18714
    ATP-dependent activity 602
      ATP-dependent activity, acting on DNA 122
        DNA clamp loader activity 8
Path 2
Term Annotations click to browse term
  molecular_function 18714
    catalytic activity 5686
      catalytic activity, acting on a nucleic acid 613
        catalytic activity, acting on DNA 246
          ATP-dependent activity, acting on DNA 122
            DNA clamp loader activity 8
paths to the root