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ONTOLOGY REPORT - ANNOTATIONS


Term:damaged DNA binding
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Accession:GO:0003684 term browser browse the term
Definition:Binding to damaged DNA.
Synonyms:related_synonym: DNA repair enzyme;   DNA repair protein



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damaged DNA binding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APEX1 apurinic/apyrimidinic endodeoxyribonuclease 1 enables ISO (PMID:12524539), (PMID:14706345), (PMID:24703901) BHF-UCL PMID:12524539 PMID:14706345 PMID:24703901 NCBI chr15:17,786,808...17,789,422
Ensembl chr15:17,786,357...17,789,422
JBrowse link
G APTX aprataxin enables ISO (PMID:14755728) UniProt PMID:14755728 NCBI chr11:50,111,003...50,155,937
Ensembl chr11:50,113,073...50,132,284
JBrowse link
G AUNIP aurora kinase A and ninein interacting protein enables ISO (PMID:29042561) UniProt PMID:29042561 NCBI chr 2:74,097,435...74,116,824
Ensembl chr 2:74,097,508...74,118,085
JBrowse link
G BRCA1 BRCA1 DNA repair associated enables ISO (MGI:2179182|PMID:11934988) MGI PMID:11934988 MGI:2179182 NCBI chr 9:19,958,941...20,025,494
Ensembl chr 9:19,958,391...20,025,494
JBrowse link
G CREBBP CREB binding protein enables IEA Ensembl GO_REF:0000107 NCBI chr 6:37,410,201...37,536,688
Ensembl chr 6:37,409,930...37,534,176
JBrowse link
G CRY2 cryptochrome circadian regulator 2 enables IEA Ensembl GO_REF:0000107 NCBI chr18:43,538,335...43,573,651
Ensembl chr18:43,539,612...43,573,875
JBrowse link
G CUL4B cullin 4B contributes_to ISO (PMID:22334663) UniProtKB PMID:22334663 NCBI chr  X:92,489,981...92,538,199
Ensembl chr  X:92,491,114...92,537,672
JBrowse link
G DCLRE1B DNA cross-link repair 1B enables IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr17:51,711,267...51,716,806
Ensembl chr17:51,711,284...51,716,345
JBrowse link
G DCLRE1C DNA cross-link repair 1C enables IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 2:21,688,822...21,725,021
Ensembl chr 2:21,688,766...21,724,248
JBrowse link
G DDB1 damage specific DNA binding protein 1 contributes_to
enables
ISO
IEA
(PMID:22334663) UniProtKB
RGD
Ensembl
PMID:12145536 PMID:22334663 GO_REF:0000107 RGD:632554 NCBI chr18:55,064,720...55,097,623
Ensembl chr18:55,064,729...55,097,627
JBrowse link
G DDB2 damage specific DNA binding protein 2 contributes_to IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr18:42,354,201...42,378,463
Ensembl chr18:42,354,572...42,377,947
JBrowse link
G EP300 E1A binding protein p300 enables ISO (PMID:24939902) UniProt PMID:24939902 NCBI chr10:24,076,538...24,156,708
Ensembl chr10:24,077,971...24,156,396
JBrowse link
G ERCC1 ERCC excision repair 1, endonuclease non-catalytic subunit enables ISO (PMID:17720715) UniProt PMID:17720715 NCBI chr 1:110,130,353...110,146,660
Ensembl chr 1:110,130,481...110,146,602
JBrowse link
G ERCC4 ERCC excision repair 4, endonuclease catalytic subunit enables ISO (PMID:11790111) UniProt PMID:11790111 NCBI chr 6:29,193,192...29,226,935
Ensembl chr 6:29,196,421...29,226,887
JBrowse link
G ERCC5 ERCC excision repair 5, endonuclease enables ISO (PMID:32821917) UniProt PMID:32821917 NCBI chr22:52,339,011...52,372,618 JBrowse link
G H2AX H2A.X variant histone enables IEA Ensembl GO_REF:0000107 NCBI chr 5:14,765,625...14,766,590
Ensembl chr 5:14,766,126...14,766,557
JBrowse link
G HMGB1 high mobility group box 1 enables ISO (PMID:17803946) UniProt PMID:17803946 NCBI chr25:9,431,223...9,558,167
Ensembl chr25:9,431,218...9,558,165
JBrowse link
G HMGB2 high mobility group box 2 enables IEA Ensembl GO_REF:0000107 NCBI chr25:23,939,024...23,941,720
Ensembl chr25:23,939,027...23,941,606
JBrowse link
G LOC485121 lysine-specific demethylase 4D enables ISO (MGI:5552986|PMID:24550317) MGI PMID:24550317 MGI:5552986 NCBI chr21:6,002,292...6,037,344
Ensembl chr21:5,987,723...6,004,783
JBrowse link
G MSH2 mutS homolog 2 enables ISO (MGI:1351797|PMID:10545954), (MGI:74950|PMID:7628020) MGI PMID:7628020 PMID:10545954 MGI:1351797 MGI:74950 NCBI chr10:49,517,448...49,594,001
Ensembl chr10:49,517,369...49,594,210
JBrowse link
G MSH3 mutS homolog 3 enables ISO (MGI:1351797|PMID:10545954) MGI PMID:10545954 MGI:1351797 NCBI chr 3:26,335,788...26,520,633
Ensembl chr 3:26,336,403...26,518,521
JBrowse link
G MSH6 mutS homolog 6 enables ISO (MGI:1351797|PMID:10545954) MGI PMID:10545954 MGI:1351797 NCBI chr10:49,825,330...49,838,036
Ensembl chr10:49,803,898...49,838,028
JBrowse link
G NBN nibrin enables ISO (MGI:2179182|PMID:11934988) MGI PMID:11934988 MGI:2179182 NCBI chr29:35,416,093...35,477,569
Ensembl chr29:35,416,093...35,477,563
JBrowse link
G NEIL2 nei like DNA glycosylase 2 enables IEA InterPro GO_REF:0000002 NCBI chr25:26,102,652...26,117,418
Ensembl chr25:26,103,111...26,117,544
JBrowse link
G NEIL3 nei like DNA glycosylase 3 enables IEA InterPro GO_REF:0000002 NCBI chr16:52,383,585...52,472,398
Ensembl chr16:52,387,389...52,436,173
JBrowse link
G NTHL1 nth like DNA glycosylase 1 enables IEA Ensembl GO_REF:0000107 NCBI chr 6:38,899,144...38,904,637
Ensembl chr 6:38,899,126...38,905,622
JBrowse link
G OGG1 8-oxoguanine DNA glycosylase enables ISO (PMID:14706345) RGD
UniProt
PMID:9801319 PMID:14706345 RGD:729091 NCBI chr20:8,486,150...8,491,448
Ensembl chr20:8,480,005...8,491,264
JBrowse link
G PCNA proliferating cell nuclear antigen enables IEA Ensembl GO_REF:0000107 NCBI chr24:16,478,774...16,485,992
Ensembl chr24:16,478,769...16,484,992
JBrowse link
G POLB DNA polymerase beta ISO RGD PMID:12388548 RGD:633643 NCBI chr16:23,306,359...23,335,352
Ensembl chr16:23,306,367...23,335,322
JBrowse link
G POLD1 DNA polymerase delta 1, catalytic subunit enables ISO (PMID:24939902) UniProt PMID:24939902 NCBI chr 1:106,302,583...106,331,353
Ensembl chr 1:106,302,574...106,331,385
JBrowse link
G POLH DNA polymerase eta enables IEA InterPro GO_REF:0000002 NCBI chr12:12,034,544...12,070,305
Ensembl chr12:12,034,583...12,069,707
JBrowse link
G POLK DNA polymerase kappa enables IEA InterPro GO_REF:0000002 NCBI chr 3:30,793,893...30,860,240
Ensembl chr 3:30,712,571...30,859,106
JBrowse link
G RAD23A RAD23 homolog A, nucleotide excision repair protein enables IEA UniProt GO_REF:0000104 NCBI chr20:49,244,330...49,250,058
Ensembl chr20:49,241,358...49,250,039
JBrowse link
G RAD23B RAD23 homolog B, nucleotide excision repair protein enables IEA UniProt GO_REF:0000104 NCBI chr11:62,732,989...62,778,957
Ensembl chr11:62,732,984...62,775,978
JBrowse link
G RBBP8 RB binding protein 8, endonuclease enables IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 7:65,218,288...65,319,696
Ensembl chr 7:65,218,297...65,297,099
JBrowse link
G REV1 REV1 DNA directed polymerase enables IEA UniProt GO_REF:0000104 NCBI chr10:43,150,885...43,247,324
Ensembl chr10:42,586,394...43,247,328
JBrowse link
G RPA1 replication protein A1 enables IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 9:45,958,566...46,034,850
Ensembl chr 9:45,958,619...46,034,328
JBrowse link
G RPA2 replication protein A2 enables ISO (PMID:27723717), (PMID:27723720), (PMID:7700386) UniProt PMID:7700386 PMID:27723717 PMID:27723720 NCBI chr 2:72,463,951...72,479,864
Ensembl chr 2:72,419,459...72,479,227
JBrowse link
G RPA3 replication protein A3 enables ISO (PMID:7700386) UniProt PMID:7700386 NCBI chr14:23,230,447...23,234,554
Ensembl chr11:2,893,352...2,893,717
JBrowse link
G RPS3 ribosomal protein S3 enables ISO (PMID:14706345), (PMID:16737853), (PMID:17560175), (PMID:18610840) UniProt PMID:14706345 PMID:16737853 PMID:17560175 PMID:18610840 NCBI chr21:23,180,515...23,187,034
Ensembl chr21:23,180,515...23,187,034
JBrowse link
G SDE2 SDE2 telomere maintenance homolog enables IEA Ensembl GO_REF:0000107 NCBI chr 7:38,857,220...38,871,584
Ensembl chr 7:38,857,234...38,870,157
JBrowse link
G SMC6 structural maintenance of chromosomes 6 enables IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr17:13,132,945...13,201,214
Ensembl chr17:13,133,236...13,201,759
JBrowse link
G TP53BP1 tumor protein p53 binding protein 1 enables IEA Ensembl GO_REF:0000107 NCBI chr30:10,263,650...10,362,646
Ensembl chr30:10,263,650...10,336,134
JBrowse link
G TP63 tumor protein p63 enables ISO (MGI:3693137|PMID:17122775) MGI PMID:17122775 MGI:3693137 NCBI chr34:21,766,861...21,985,095
Ensembl chr34:21,766,496...21,983,046
JBrowse link
G UNG uracil DNA glycosylase enables ISO (PMID:18973764) UniProt PMID:18973764 NCBI chr26:17,900,354...17,911,126
Ensembl chr26:17,901,357...17,911,288
JBrowse link
G XPA XPA, DNA damage recognition and repair factor enables IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr11:54,976,978...54,996,140
Ensembl chr11:54,976,976...54,996,065
JBrowse link
G XPC XPC complex subunit, DNA damage recognition and repair factor enables IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr20:4,299,644...4,328,826
Ensembl chr20:4,300,386...4,328,768
JBrowse link
G XRCC6 X-ray repair cross complementing 6 enables IEA InterPro GO_REF:0000002 NCBI chr10:23,637,905...23,661,618
Ensembl chr10:23,638,237...23,661,480
JBrowse link
8-hydroxy-2'-deoxyguanosine DNA binding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BLM BLM RecQ like helicase enables IEA Ensembl GO_REF:0000107 NCBI chr 3:53,408,120...53,506,728
Ensembl chr 3:53,408,217...53,473,146
JBrowse link
G POT1 protection of telomeres 1 enables IEA Ensembl GO_REF:0000107 NCBI chr14:10,987,385...11,067,473
Ensembl chr14:10,987,494...11,066,956
JBrowse link
G WRN WRN RecQ like helicase enables ISO (PMID:19734539) BHF-UCL PMID:19734539 NCBI chr16:33,164,662...33,304,466
Ensembl chr16:33,167,364...33,304,625
JBrowse link
DNA-(abasic site) binding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APEX1 apurinic/apyrimidinic endodeoxyribonuclease 1 enables IEA Ensembl GO_REF:0000107 NCBI chr15:17,786,808...17,789,422
Ensembl chr15:17,786,357...17,789,422
JBrowse link
oxidized DNA binding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G XRCC1 X-ray repair cross complementing 1 enables IEA Ensembl GO_REF:0000107 NCBI chr 1:111,548,719...111,571,816
Ensembl chr 1:111,548,719...111,571,816
JBrowse link
oxidized purine DNA binding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MSH2 mutS homolog 2 contributes_to IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr10:49,517,448...49,594,001
Ensembl chr10:49,517,369...49,594,210
JBrowse link
G MSH3 mutS homolog 3 NOT|contributes_to ISO (PMID:11756455) HGNC PMID:11756455 NCBI chr 3:26,335,788...26,520,633
Ensembl chr 3:26,336,403...26,518,521
JBrowse link
G MSH6 mutS homolog 6 contributes_to ISO (PMID:11756455), (PMID:11801590) HGNC PMID:11756455 PMID:11801590 NCBI chr10:49,825,330...49,838,036
Ensembl chr10:49,803,898...49,838,028
JBrowse link
G OGG1 8-oxoguanine DNA glycosylase enables ISO (PMID:14706345) UniProt PMID:14706345 NCBI chr20:8,486,150...8,491,448
Ensembl chr20:8,480,005...8,491,264
JBrowse link
G RECQL4 RecQ like helicase 4 enables ISO (PMID:22039056) BHF-UCL PMID:22039056 NCBI chr13:37,930,906...37,936,653
Ensembl chr13:37,930,621...37,936,753
JBrowse link
G RPS3 ribosomal protein S3 enables IEA Ensembl GO_REF:0000107 NCBI chr21:23,180,515...23,187,034
Ensembl chr21:23,180,515...23,187,034
JBrowse link
oxidized pyrimidine DNA binding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G RPS3 ribosomal protein S3 enables IEA Ensembl GO_REF:0000107 NCBI chr21:23,180,515...23,187,034
Ensembl chr21:23,180,515...23,187,034
JBrowse link
single-strand break-containing DNA binding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APTX aprataxin enables IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr11:50,111,003...50,155,937
Ensembl chr11:50,113,073...50,132,284
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 15363
    binding 14431
      heterocyclic compound binding 3611
        nucleic acid binding 2386
          DNA binding 1640
            damaged DNA binding 53
              DNA-(abasic site) binding 1
              alkylated DNA binding + 0
              oxidized DNA binding + 10
              single-strand break-containing DNA binding 1
paths to the root