Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

ONTOLOGY REPORT - ANNOTATIONS


Term:damaged DNA binding
go back to main search page
Accession:GO:0003684 term browser browse the term
Definition:Binding to damaged DNA.
Synonyms:related_synonym: DNA repair enzyme;   DNA repair protein



show annotations for term's descendants           Sort by:
 
damaged DNA binding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APEX1 apurinic/apyrimidinic endodeoxyribonuclease 1 enables ISO (PMID:12524539), (PMID:14706345), (PMID:24703901) BHF-UCL PMID:12524539 PMID:14706345 PMID:24703901 NCBI chr14:1,329,745...1,332,315
Ensembl chr14:19,381,911...19,384,542
JBrowse link
G APTX aprataxin enables ISO (PMID:14755728) UniProt PMID:14755728 NCBI chr 9:32,747,409...32,819,270
Ensembl chr 9:33,556,419...33,585,060
JBrowse link
G AUNIP aurora kinase A and ninein interacting protein enables ISO (PMID:29042561) UniProt PMID:29042561 NCBI chr 1:25,090,690...25,118,062
Ensembl chr 1:26,157,953...26,185,578
JBrowse link
G BRCA1 BRCA1 DNA repair associated enables ISO (MGI:2179182|PMID:11934988) MGI PMID:11934988 MGI:2179182 NCBI chr17:14,197,946...14,279,064
Ensembl chr17:14,428,526...14,506,815
JBrowse link
G CREBBP CREB binding protein enables ISO (PMID:24939902) UniProt PMID:24939902 NCBI chr16:2,645,445...2,800,975
Ensembl chr16:3,820,519...3,974,206
JBrowse link
G CRY2 cryptochrome circadian regulator 2 enables ISO (PMID:12627958) UniProt PMID:12627958 NCBI chr11:45,801,504...45,837,357
Ensembl chr11:46,293,717...46,329,759
JBrowse link
G CUL4B cullin 4B contributes_to ISO (PMID:22334663) UniProtKB PMID:22334663 NCBI chr  X:109,798,279...109,870,469
Ensembl chr  X:119,985,116...120,034,702
JBrowse link
G DDB1 damage specific DNA binding protein 1 contributes_to ISO (PMID:22334663) RGD
UniProtKB
PMID:12145536 PMID:22334663 RGD:632554 NCBI chr11:56,599,422...56,633,140
Ensembl chr11:59,964,235...59,997,805
JBrowse link
G DDB2 damage specific DNA binding protein 2 contributes_to ISO (PMID:22334663) UniProtKB PMID:22334663 NCBI chr11:47,161,345...47,185,526
Ensembl chr11:47,714,723...47,738,761
JBrowse link
G EP300 E1A binding protein p300 enables ISO (PMID:24939902) UniProt PMID:24939902 NCBI chr22:21,986,467...22,076,921
Ensembl chr22:40,079,503...40,168,604
JBrowse link
G ERCC1 ERCC excision repair 1, endonuclease non-catalytic subunit enables ISO (PMID:17720715) UniProt PMID:17720715 NCBI chr19:42,356,039...42,427,754
Ensembl chr19:50,951,674...50,968,430
JBrowse link
G ERCC4 ERCC excision repair 4, endonuclease catalytic subunit enables ISO (PMID:11790111) UniProt PMID:11790111 NCBI chr16:12,848,334...12,880,480
Ensembl chr16:14,272,417...14,304,496
JBrowse link
G ERCC5 ERCC excision repair 5, endonuclease enables ISO (PMID:32821917) UniProt PMID:32821917 NCBI chr13:84,005,950...84,036,710
Ensembl chr13:103,096,344...103,174,182
JBrowse link
G HMGB1 high mobility group box 1 enables ISO (PMID:17803946) UniProt PMID:17803946 NCBI chr13:11,737,942...11,894,923
Ensembl chr13:30,174,899...30,179,527
JBrowse link
G HMGB2 high mobility group box 2 enables ISO (PMID:8226934) UniProt PMID:8226934 NCBI chr 4:165,559,848...165,562,625
Ensembl chr 4:177,797,457...177,800,952
JBrowse link
G KDM4D lysine demethylase 4D enables ISO (MGI:5552986|PMID:24550317) MGI PMID:24550317 MGI:5552986 NCBI chr11:89,987,537...90,013,421 JBrowse link
G LOC100994157 histone H2AX enables ISO (MGI:2179182|PMID:11934988) MGI PMID:11934988 MGI:2179182 NCBI chr11:113,932,078...113,933,679 JBrowse link
G MSH2 mutS homolog 2 enables ISO (MGI:1351797|PMID:10545954), (MGI:74950|PMID:7628020) MGI PMID:7628020 PMID:10545954 MGI:1351797 MGI:74950 NCBI chr2A:47,524,468...47,602,376
Ensembl chr2A:48,447,207...48,554,461
JBrowse link
G MSH3 mutS homolog 3 enables ISO (MGI:1351797|PMID:10545954) MGI PMID:10545954 MGI:1351797 NCBI chr 5:34,408,469...34,663,483
Ensembl chr 5:34,719,322...34,938,469
JBrowse link
G MSH6 mutS homolog 6 enables ISO (MGI:1351797|PMID:10545954) MGI PMID:10545954 MGI:1351797 NCBI chr2A:47,901,591...47,926,662
Ensembl chr2A:48,824,350...48,849,779
JBrowse link
G NBN nibrin enables ISO (MGI:2179182|PMID:11934988) MGI PMID:11934988 MGI:2179182 NCBI chr 8:86,622,797...86,674,202
Ensembl chr 8:88,575,198...88,626,307
JBrowse link
G NTHL1 nth like DNA glycosylase 1 enables ISO (PMID:9927729) UniProt PMID:9927729 NCBI chr16:655,433...663,521
Ensembl chr16:2,127,858...2,135,656
JBrowse link
G OGG1 8-oxoguanine DNA glycosylase enables ISO (PMID:14706345) RGD
UniProt
PMID:9801319 PMID:14706345 RGD:729091 NCBI chr 3:9,702,311...9,742,283
Ensembl chr 3:9,940,955...9,947,335
JBrowse link
G PCNA proliferating cell nuclear antigen enables ISO (PMID:24939902) UniProt PMID:24939902 NCBI chr20:5,134,930...5,146,603
Ensembl chr20:4,927,731...4,939,440
JBrowse link
G POLB DNA polymerase beta ISO RGD PMID:12388548 RGD:633643 NCBI chr 8:41,582,370...41,615,950
Ensembl chr 8:39,026,991...39,060,464
JBrowse link
G POLD1 DNA polymerase delta 1, catalytic subunit enables ISO (PMID:24939902) UniProt PMID:24939902 NCBI chr19:47,347,919...47,381,772
Ensembl chr19:56,251,356...56,297,611
JBrowse link
G RBBP8 RB binding protein 8, endonuclease enables ISO (PMID:18716619) UniProt PMID:18716619 NCBI chr18:16,181,652...16,274,597
Ensembl chr18:19,811,989...19,903,522
JBrowse link
G RPA1 replication protein A1 enables ISO (PMID:27723717), (PMID:27723720), (PMID:7700386) UniProt PMID:7700386 PMID:27723717 PMID:27723720 NCBI chr17:1,813,610...1,886,093
Ensembl chr17:1,705,380...1,775,596
JBrowse link
G RPA2 replication protein A2 enables ISO (PMID:27723717), (PMID:27723720), (PMID:7700386) UniProt PMID:7700386 PMID:27723717 PMID:27723720 NCBI chr 1:27,151,784...27,175,110
Ensembl chr 1:28,191,731...28,214,666
JBrowse link
G RPA3 replication protein A3 enables ISO (PMID:7700386) UniProt PMID:7700386 NCBI chr 7:8,361,623...8,365,098
Ensembl chr 7:7,713,629...7,717,169
JBrowse link
G RPS3 ribosomal protein S3 enables ISO (PMID:14706345), (PMID:16737853), (PMID:17560175), (PMID:18610840) UniProt PMID:14706345 PMID:16737853 PMID:17560175 PMID:18610840 NCBI chr11:70,460,702...70,466,909
Ensembl chr11:73,762,794...73,768,982
JBrowse link
G SDE2 SDE2 telomere maintenance homolog enables ISO (PMID:27906959) UniProt PMID:27906959 NCBI chr 1:201,443,945...201,460,668
Ensembl chr 1:206,441,517...206,457,679
JBrowse link
G TP53BP1 tumor protein p53 binding protein 1 enables ISO (MGI:2179182|PMID:11934988) MGI PMID:11934988 MGI:2179182 NCBI chr15:22,364,696...22,472,499
Ensembl chr15:40,519,012...40,626,741
JBrowse link
G TP63 tumor protein p63 enables ISO (MGI:3693137|PMID:17122775) MGI PMID:17122775 MGI:3693137 NCBI chr 3:186,651,879...186,918,300
Ensembl chr 3:195,199,167...195,474,104
JBrowse link
G UNG uracil DNA glycosylase enables ISO (PMID:18973764) UniProt PMID:18973764 NCBI chr12:106,674,073...106,687,054
Ensembl chr12:110,067,879...110,080,891
JBrowse link
G XPA XPA, DNA damage recognition and repair factor enables ISO (PMID:7700386) UniProt PMID:7700386 NCBI chr 9:68,726,723...68,788,049
Ensembl chr 9:96,886,795...96,909,254
JBrowse link
G XPC XPC complex subunit, DNA damage recognition and repair factor enables ISO (PMID:10873465), (PMID:12509299)
(MGI:5427285|PMID:22431748)
UniProt
MGI
PMID:10873465 PMID:12509299 PMID:22431748 MGI:5427285 NCBI chr 3:14,063,499...14,097,023
Ensembl chr 3:14,403,958...14,437,377
JBrowse link
8-hydroxy-2'-deoxyguanosine DNA binding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BLM BLM RecQ like helicase enables ISO (PMID:19734539) BHF-UCL PMID:19734539 NCBI chr15:69,407,248...69,508,070
Ensembl chr15:88,607,157...88,707,864
JBrowse link
G POT1 protection of telomeres 1 enables ISO (PMID:19734539) BHF-UCL PMID:19734539 NCBI chr 7:116,807,913...116,926,998
Ensembl chr 7:129,487,571...129,605,558
JBrowse link
G WRN WRN RecQ like helicase enables ISO (PMID:19734539) BHF-UCL PMID:19734539 NCBI chr 8:30,353,643...30,492,978
Ensembl chr 8:27,541,145...27,679,855
JBrowse link
DNA-(abasic site) binding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APEX1 apurinic/apyrimidinic endodeoxyribonuclease 1 enables ISO (PMID:9804798) UniProt PMID:9804798 NCBI chr14:1,329,745...1,332,315
Ensembl chr14:19,381,911...19,384,542
JBrowse link
oxidized DNA binding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G XRCC1 X-ray repair cross complementing 1 enables ISO (PMID:28002403) UniProt PMID:28002403 NCBI chr19:40,485,052...40,522,188
Ensembl chr19:49,094,014...49,125,520
JBrowse link
oxidized purine DNA binding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MSH2 mutS homolog 2 contributes_to ISO (PMID:11756455), (PMID:11801590) HGNC PMID:11756455 PMID:11801590 NCBI chr2A:47,524,468...47,602,376
Ensembl chr2A:48,447,207...48,554,461
JBrowse link
G MSH3 mutS homolog 3 NOT|contributes_to ISO (PMID:11756455) HGNC PMID:11756455 NCBI chr 5:34,408,469...34,663,483
Ensembl chr 5:34,719,322...34,938,469
JBrowse link
G MSH6 mutS homolog 6 contributes_to ISO (PMID:11756455), (PMID:11801590) HGNC PMID:11756455 PMID:11801590 NCBI chr2A:47,901,591...47,926,662
Ensembl chr2A:48,824,350...48,849,779
JBrowse link
G OGG1 8-oxoguanine DNA glycosylase enables ISO (PMID:14706345) UniProt PMID:14706345 NCBI chr 3:9,702,311...9,742,283
Ensembl chr 3:9,940,955...9,947,335
JBrowse link
G RPS3 ribosomal protein S3 enables ISO (PMID:14706345) UniProt PMID:14706345 NCBI chr11:70,460,702...70,466,909
Ensembl chr11:73,762,794...73,768,982
JBrowse link
oxidized pyrimidine DNA binding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G RPS3 ribosomal protein S3 enables ISO (PMID:19656744) UniProt PMID:19656744 NCBI chr11:70,460,702...70,466,909
Ensembl chr11:73,762,794...73,768,982
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 15014
    binding 14203
      heterocyclic compound binding 2538
        nucleic acid binding 1874
          DNA binding 1378
            damaged DNA binding 41
              DNA-(abasic site) binding 1
              alkylated DNA binding + 0
              oxidized DNA binding + 9
              single-strand break-containing DNA binding 0
paths to the root