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Pathways

ONTOLOGY REPORT - ANNOTATIONS


Term:retinal pigment epithelium development
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Accession:GO:0003406 term browser browse the term
Definition:The progression of the retinal pigment epithelium over time, from its initial formation to the mature structure. The retinal pigment epithelium is the melanin-containing layer of cells between the retina and the choroid that absorbs scattered and reflected light and removes waste products produced by the photoreceptor cells.
Synonyms:related_synonym: RPE development



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retinal pigment epithelium development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cfh complement factor H acts_upstream_of_or_within ISO (MGI:5532224|PMID:23844226), (MGI:5648643|PMID:25991857) RGD PMID:23844226 PMID:25991857 MGI:5532224 MGI:5648643 NCBI chr13:51,512,376...51,613,829
Ensembl chr13:51,511,828...51,613,838
JBrowse link
G Ihh Indian hedgehog signaling molecule acts_upstream_of_or_within ISO MGI:1934258 (MGI:3807419|PMID:18582859) RGD PMID:18582859 MGI:3807419 NCBI chr 9:76,504,315...76,510,532
Ensembl chr 9:76,504,315...76,510,532
JBrowse link
G Med1 mediator complex subunit 1 involved_in ISO (MGI:2158098|PMID:11724781) RGD PMID:11724781 MGI:2158098 NCBI chr10:83,145,538...83,189,260
Ensembl chr10:83,145,568...83,189,299
JBrowse link
G Mfsd2a MFSD2 lysolipid transporter A, lysophospholipid acts_upstream_of_or_within ISO (MGI:5789479|PMID:27008858) RGD PMID:27008858 MGI:5789479 NCBI chr 5:135,225,801...135,240,744
Ensembl chr 5:135,225,816...135,240,690
JBrowse link
G Ndp norrin cystine knot growth factor NDP acts_upstream_of_or_within ISO MGI:2676199 (MGI:3655326|PMID:9071226) RGD PMID:9071226 MGI:3655326 NCBI chr  X:5,796,487...5,820,934
Ensembl chr  X:5,796,487...5,820,934
JBrowse link
G Pax2 paired box 2 involved_in ISS
ISO
GO_REF:0000024
(MGI:84247|PMID:8951055)
UniProt
RGD
PMID:8951055 GO_REF:0000024 MGI:84247 NCBI chr 1:243,616,509...243,697,454
Ensembl chr 1:243,616,606...243,695,321
JBrowse link
G Rarb retinoic acid receptor, beta acts_upstream_of_or_within ISO MGI:97858 (MGI:81656|PMID:8681798) RGD PMID:8681798 MGI:81656 NCBI chr15:8,700,533...9,051,288
Ensembl chr15:8,406,492...9,051,288
JBrowse link
G Rarg retinoic acid receptor, gamma acts_upstream_of_or_within ISO MGI:97857 (MGI:81656|PMID:8681798) RGD PMID:8681798 MGI:81656 NCBI chr 7:133,367,833...133,390,301
Ensembl chr 7:133,367,833...133,390,177
JBrowse link
G Tbc1d32 TBC1 domain family, member 32 acts_upstream_of_or_within ISO MGI:4440463 (MGI:4439200|PMID:20159594) RGD PMID:20159594 MGI:4439200 NCBI chr20:35,359,865...35,590,992
Ensembl chr20:35,359,863...35,590,415
JBrowse link
G Tmem135 transmembrane protein 135 acts_upstream_of_or_within ISO MGI:5811600 (MGI:6468192|PMID:33064130) RGD PMID:33064130 MGI:6468192 NCBI chr 1:143,006,343...143,279,824
Ensembl chr 1:143,006,344...143,221,171
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19553
    developmental process 6909
      anatomical structure development 6435
        retina development in camera-type eye 227
          retinal pigment epithelium development 10
Path 2
Term Annotations click to browse term
  biological_process 19553
    developmental process 6909
      anatomical structure development 6435
        multicellular organism development 5184
          system development 4463
            sensory system development 487
              visual system development 482
                eye development 479
                  camera-type eye development 429
                    retina development in camera-type eye 227
                      retinal pigment epithelium development 10
paths to the root