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ONTOLOGY REPORT - ANNOTATIONS

Term:mesenchymal to epithelial transition involved in metanephros morphogenesis
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Accession:GO:0003337 term browser browse the term
Definition:A transition where a mesenchymal cell establishes apical/basolateral polarity,forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell that will contribute to the shaping of the metanephros.
Synonyms:related_synonym: metanephric mesenchyme to epithelial transition


show annotations for term's descendants           Sort by:
mesenchymal to epithelial transition involved in metanephros morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GDNF glial cell derived neurotrophic factor involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:37,812,677...37,840,041
Ensembl chr 5:37,812,677...37,840,041 		JBrowse link
G GREM1 gremlin 1, DAN family BMP antagonist involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:32,718,004...32,745,106
Ensembl chr15:32,718,004...32,745,106 		JBrowse link
G PAX2 paired box 2 involved_in ISS UniProt GO_REF:0000024 NCBI chr10:100,735,396...100,829,944
Ensembl chr10:100,735,396...100,829,944 		JBrowse link
G PAX8 paired box 8 involved_in IEP (PMID:8861958) UniProt PMID:8861958 NCBI chr 2:113,215,997...113,278,921
Ensembl chr 2:113,215,997...113,278,921 		JBrowse link
G SALL1 spalt like transcription factor 1 involved_in
acts_upstream_of		 IEP
ISO		 (PMID:11511981)
(PMID:24550112)		 UniProt
MGI		 PMID:11511981 PMID:24550112 NCBI chr16:51,135,982...51,152,334
Ensembl chr16:51,135,982...51,152,334 		JBrowse link
G SIX2 SIX homeobox 2 involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr 2:45,005,182...45,009,452
Ensembl chr 2:45,005,182...45,009,452 		JBrowse link
mesenchymal to epithelial transition involved in metanephric renal vesicle formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SMO smoothened, frizzled class receptor involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr 7:129,188,633...129,213,545
Ensembl chr 7:129,188,633...129,213,545 		JBrowse link
negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CITED1 Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 1 involved_in ISO PMID:15843474 UniProt PMID:15843474 RGD:8554075 NCBI chr  X:72,301,646...72,307,157
Ensembl chr  X:72,301,638...72,307,187 		JBrowse link
G CTNNB1 catenin beta 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:17537789) Ensembl
MGI		 PMID:17537789 GO_REF:0000107 NCBI chr 3:41,199,505...41,240,443
Ensembl chr 3:41,194,741...41,260,096 		JBrowse link
G SALL1 spalt like transcription factor 1 acts_upstream_of_or_within ISO (PMID:24550112) MGI PMID:24550112 NCBI chr16:51,135,982...51,152,334
Ensembl chr16:51,135,982...51,152,334 		JBrowse link
G STAT1 signal transducer and activator of transcription 1 involved_in ISS UniProt GO_REF:0000024 NCBI chr 2:190,969,149...191,014,171
Ensembl chr 2:190,908,460...191,020,960 		JBrowse link
positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GDNF glial cell derived neurotrophic factor involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:37,812,677...37,840,041
Ensembl chr 5:37,812,677...37,840,041 		JBrowse link
G LIF LIF interleukin 6 family cytokine involved_in IDA (PMID:20624457) BHF-UCL PMID:20624457 NCBI chr22:30,240,453...30,246,759
Ensembl chr22:30,240,453...30,246,759 		JBrowse link
G PAX2 paired box 2 involved_in ISS UniProt GO_REF:0000024 NCBI chr10:100,735,396...100,829,944
Ensembl chr10:100,735,396...100,829,944 		JBrowse link
G PAX8 paired box 8 involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr 2:113,215,997...113,278,921
Ensembl chr 2:113,215,997...113,278,921 		JBrowse link
regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G WNT9B Wnt family member 9B involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16054034) Ensembl
MGI		 PMID:16054034 GO_REF:0000107 NCBI chr17:46,833,189...46,886,738
Ensembl chr17:46,833,201...46,886,730 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19669
    cellular process 18300
      cellular developmental process 5182
        cell differentiation 5181
          epithelial cell differentiation 900
            epithelial cell differentiation involved in kidney development 52
              mesenchymal to epithelial transition involved in metanephros morphogenesis 12
                mesenchymal to epithelial transition involved in metanephric renal vesicle formation 1
                negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis 4
                positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis 4
                regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis + 9
Path 2
Term Annotations click to browse term
  biological_process 19669
    developmental process 7610
      anatomical structure development 7020
        multicellular organism development 5632
          system development 4908
            renal system development 413
              kidney development 401
                nephron development 190
                  nephron epithelium development 144
                    renal vesicle development 20
                      renal vesicle morphogenesis 18
                        metanephric renal vesicle morphogenesis 15
                          mesenchymal to epithelial transition involved in metanephros morphogenesis 12
                            mesenchymal to epithelial transition involved in metanephric renal vesicle formation 1
                            negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis 4
                            positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis 4
                            regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis + 9
paths to the root