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ONTOLOGY REPORT - ANNOTATIONS


Term:mesenchymal to epithelial transition involved in metanephros morphogenesis
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Accession:GO:0003337 term browser browse the term
Definition:A transition where a mesenchymal cell establishes apical/basolateral polarity,forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell that will contribute to the shaping of the metanephros.
Synonyms:related_synonym: metanephric mesenchyme to epithelial transition



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mesenchymal to epithelial transition involved in metanephros morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gdnf glial cell derived neurotrophic factor involved_in IEA
ISO
IDA
GO_REF:0000107
(PMID:10322633)
PMID:17522159
Ensembl
RGD
PMID:10322633 PMID:17522159 GO_REF:0000107, RGD:8656002 NCBI chr 2:56,894,022...56,919,935
Ensembl chr 2:56,895,010...56,917,209
JBrowse link
G Grem1 gremlin 1, DAN family BMP antagonist involved_in ISO (PMID:17522159) RGD PMID:17522159 NCBI chr 3:100,512,317...100,524,001
Ensembl chr 3:100,512,313...100,524,082
JBrowse link
G Pax2 paired box 2 involved_in ISS
ISO
GO_REF:0000024
(PMID:10322633)
UniProt
RGD
PMID:10322633 GO_REF:0000024 NCBI chr 1:243,616,509...243,697,454
Ensembl chr 1:243,616,606...243,695,321
JBrowse link
G Pax8 paired box 8 involved_in ISO (PMID:8861958) RGD PMID:8861958 NCBI chr 3:7,185,721...7,242,363
Ensembl chr 3:7,185,723...7,242,363
JBrowse link
G Sall1 spalt-like transcription factor 1 involved_in
acts_upstream_of
ISO (PMID:11511981)
(PMID:11688560)
MGI:3603818 (PMID:24550112)
RGD PMID:11511981 PMID:11688560 PMID:24550112 NCBI chr19:18,005,782...18,022,705
Ensembl chr19:18,007,503...18,022,705
JBrowse link
G Six2 SIX homeobox 2 involved_in ISO (PMID:10322633) RGD PMID:10322633 NCBI chr 6:8,974,859...8,981,345
Ensembl chr 6:8,967,157...8,981,193
JBrowse link
mesenchymal to epithelial transition involved in metanephric renal vesicle formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Smo smoothened, frizzled class receptor involved_in IEA
ISS
ISO
GO_REF:0000107
GO_REF:0000024
(PMID:16396903)
Ensembl
UniProt
RGD
PMID:16396903 GO_REF:0000024 GO_REF:0000107 NCBI chr 4:58,343,626...58,373,823
Ensembl chr 4:58,343,529...58,373,829
JBrowse link
negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cited1 Cbp/p300-interacting transactivator with Glu/Asp-rich carboxy-terminal domain 1 involved_in IMP PMID:15843474 UniProt PMID:15843474 RGD:8554075 NCBI chr  X:67,350,376...67,355,072
Ensembl chr  X:67,350,373...67,355,162
JBrowse link
G Ctnnb1 catenin beta 1 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(PMID:17537789)
Ensembl
RGD
PMID:17537789 GO_REF:0000107 NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111
JBrowse link
G Sall1 spalt-like transcription factor 1 acts_upstream_of_or_within ISO MGI:3603818 (PMID:24550112) RGD PMID:24550112 NCBI chr19:18,005,782...18,022,705
Ensembl chr19:18,007,503...18,022,705
JBrowse link
positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gdnf glial cell derived neurotrophic factor involved_in IEA
ISO
GO_REF:0000107
(PMID:8657306)
Ensembl
RGD
PMID:8657306 GO_REF:0000107 NCBI chr 2:56,894,022...56,919,935
Ensembl chr 2:56,895,010...56,917,209
JBrowse link
G Lif LIF, interleukin 6 family cytokine involved_in ISO
IEA
(PMID:20624457)
GO_REF:0000107
RGD
Ensembl
PMID:20624457 GO_REF:0000107 NCBI chr14:79,131,049...79,140,486
Ensembl chr14:79,134,574...79,140,482
JBrowse link
G Pax2 paired box 2 involved_in ISS
ISO
GO_REF:0000024
UniProtKB:Q00288 (PMID:12435636)
UniProt
RGD
PMID:12435636 GO_REF:0000024 NCBI chr 1:243,616,509...243,697,454
Ensembl chr 1:243,616,606...243,695,321
JBrowse link
G Pax8 paired box 8 involved_in ISS
ISO
GO_REF:0000024
(PMID:12435636)
UniProt
RGD
PMID:12435636 GO_REF:0000024 NCBI chr 3:7,185,721...7,242,363
Ensembl chr 3:7,185,723...7,242,363
JBrowse link
regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Wnt9b Wnt family member 9B acts_upstream_of_or_within ISO MGI:3526437 (PMID:16054034) RGD PMID:16054034 NCBI chr10:88,635,330...88,657,035
Ensembl chr10:88,635,331...88,657,035
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20536
    cellular process 19525
      cellular developmental process 4812
        cell differentiation 4811
          epithelial cell differentiation 857
            epithelial cell differentiation involved in kidney development 53
              mesenchymal to epithelial transition involved in metanephros morphogenesis 11
                mesenchymal to epithelial transition involved in metanephric renal vesicle formation 1
                negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis 3
                positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis 4
                regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis + 8
Path 2
Term Annotations click to browse term
  biological_process 20536
    developmental process 7109
      anatomical structure development 6611
        multicellular organism development 5330
          system development 4612
            renal system development 423
              kidney development 409
                nephron development 192
                  nephron epithelium development 143
                    renal vesicle development 19
                      renal vesicle morphogenesis 17
                        metanephric renal vesicle morphogenesis 14
                          mesenchymal to epithelial transition involved in metanephros morphogenesis 11
                            mesenchymal to epithelial transition involved in metanephric renal vesicle formation 1
                            negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis 3
                            positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis 4
                            regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis + 8
paths to the root