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ONTOLOGY REPORT - ANNOTATIONS


Term:mesenchymal to epithelial transition involved in metanephros morphogenesis
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Accession:GO:0003337 term browser browse the term
Definition:A transition where a mesenchymal cell establishes apical/basolateral polarity,forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell that will contribute to the shaping of the metanephros.
Synonyms:related_synonym: metanephric mesenchyme to epithelial transition



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mesenchymal to epithelial transition involved in metanephros morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp4 bone morphogenetic protein 4 involved_in ISS
ISO
IEA
GO_REF:0000024
(PMID:10706139)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:10706139 GO_REF:0000024 GO_REF:0000107 NCBI chr15:19,618,538...19,633,494
Ensembl chr15:19,618,542...19,623,306
JBrowse link
G Gdnf glial cell derived neurotrophic factor involved_in
acts_upstream_of_or_within
IEA
ISO
IDA
GO_REF:0000107
(PMID:10322633)
PMID:17522159
Ensembl
RGD
PMID:10322633 PMID:17522159 GO_REF:0000107, RGD:8656002 NCBI chr 2:56,893,992...56,919,935
Ensembl chr 2:56,895,010...56,917,209
JBrowse link
G Grem1 gremlin 1, DAN family BMP antagonist involved_in ISO (MGI:3714585|PMID:17522159) RGD PMID:17522159 MGI:3714585 NCBI chr 3:100,512,317...100,524,001
Ensembl chr 3:100,512,313...100,524,082
JBrowse link
G Pax2 paired box 2 involved_in
acts_upstream_of_or_within
ISS
ISO
GO_REF:0000024
(PMID:10322633)
UniProt
RGD
PMID:10322633 GO_REF:0000024 NCBI chr 1:243,616,509...243,697,454
Ensembl chr 1:243,616,606...243,695,321
JBrowse link
G Pax8 paired box 8 involved_in ISO (PMID:8861958) RGD PMID:8861958 NCBI chr 3:7,185,721...7,242,363
Ensembl chr 3:7,185,723...7,242,363
JBrowse link
G Sall1 spalt-like transcription factor 1 involved_in ISO (PMID:11511981)
(MGI:2149437|PMID:11688560)
RGD PMID:11511981 PMID:11688560 MGI:2149437 NCBI chr19:18,005,782...18,022,705
Ensembl chr19:18,007,503...18,022,705
JBrowse link
G Six2 SIX homeobox 2 acts_upstream_of_or_within ISO (PMID:10322633) RGD PMID:10322633 NCBI chr 6:8,974,859...8,981,345
Ensembl chr 6:8,967,157...8,981,193
JBrowse link
mesenchymal to epithelial transition involved in metanephric renal vesicle formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Smo smoothened, frizzled class receptor involved_in IEA
ISS
ISO
GO_REF:0000107
GO_REF:0000024
(MGI:3611729|PMID:16396903)
Ensembl
UniProt
RGD
PMID:16396903 GO_REF:0000024 GO_REF:0000107 MGI:3611729 NCBI chr 4:58,344,101...58,372,828
Ensembl chr 4:58,343,529...58,373,829
JBrowse link
negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cited1 Cbp/p300-interacting transactivator with Glu/Asp-rich carboxy-terminal domain 1 involved_in IMP PMID:15843474 UniProt PMID:15843474 RGD:8554075 NCBI chr  X:67,350,376...67,355,072
Ensembl chr  X:67,350,373...67,355,162
JBrowse link
G Ctnnb1 catenin beta 1 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(MGI:3714576|PMID:17537789)
Ensembl
RGD
PMID:17537789 GO_REF:0000107 MGI:3714576 NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111
JBrowse link
G Sall1 spalt-like transcription factor 1 acts_upstream_of_or_within ISO MGI:3603818 (MGI:5563280|PMID:24550112) RGD PMID:24550112 MGI:5563280 NCBI chr19:18,005,782...18,022,705
Ensembl chr19:18,007,503...18,022,705
JBrowse link
positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gdnf glial cell derived neurotrophic factor involved_in IEA
ISO
GO_REF:0000107
(MGI:81286|PMID:8657306)
Ensembl
RGD
PMID:8657306 GO_REF:0000107 MGI:81286 NCBI chr 2:56,893,992...56,919,935
Ensembl chr 2:56,895,010...56,917,209
JBrowse link
G Lif LIF, interleukin 6 family cytokine involved_in ISO
IEA
(PMID:20624457)
GO_REF:0000107
RGD
Ensembl
PMID:20624457 GO_REF:0000107 NCBI chr14:79,131,049...79,140,486
Ensembl chr14:79,134,574...79,140,482
JBrowse link
G Pax2 paired box 2 involved_in ISS
ISO
GO_REF:0000024
UniProtKB:Q00288 (MGI:2445273|PMID:12435636)
UniProt
RGD
PMID:12435636 GO_REF:0000024 MGI:2445273 NCBI chr 1:243,616,509...243,697,454
Ensembl chr 1:243,616,606...243,695,321
JBrowse link
G Pax8 paired box 8 involved_in ISS
ISO
GO_REF:0000024
(MGI:2445273|PMID:12435636)
UniProt
RGD
PMID:12435636 GO_REF:0000024 MGI:2445273 NCBI chr 3:7,185,721...7,242,363
Ensembl chr 3:7,185,723...7,242,363
JBrowse link
regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Wnt9b Wnt family member 9B acts_upstream_of_or_within ISO MGI:3526437 (MGI:3588895|PMID:16054034) RGD PMID:16054034 MGI:3588895 NCBI chr10:88,635,330...88,657,035
Ensembl chr10:88,635,331...88,657,035
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19497
    cellular process 18359
      cellular developmental process 4543
        cell differentiation 4448
          epithelial cell differentiation 725
            epithelial cell differentiation involved in kidney development 49
              mesenchymal to epithelial transition involved in metanephros morphogenesis 12
                mesenchymal to epithelial transition involved in metanephric renal vesicle formation 1
                negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis 3
                positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis 4
                regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis + 8
Path 2
Term Annotations click to browse term
  biological_process 19497
    developmental process 6889
      anatomical structure development 6306
        multicellular organism development 5727
          system development 5373
            urogenital system development 439
              renal system development 391
                kidney development 377
                  nephron development 168
                    nephron epithelium development 126
                      renal vesicle development 20
                        renal vesicle morphogenesis 18
                          metanephric renal vesicle morphogenesis 15
                            mesenchymal to epithelial transition involved in metanephros morphogenesis 12
                              mesenchymal to epithelial transition involved in metanephric renal vesicle formation 1
                              negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis 3
                              positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis 4
                              regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis + 8
paths to the root