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ONTOLOGY REPORT - ANNOTATIONS


Term:type B pancreatic cell fate commitment
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Accession:GO:0003327 term browser browse the term
Definition:The commitment of a cell to a type B pancreatic cell fate and its capacity to differentiate into a type B pancreatic cell. A type B pancreatic cell is a cell located towards center of the islets of Langerhans that secretes insulin.
Synonyms:exact_synonym: pancreatic B cell fate commitment


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type B pancreatic cell fate commitment term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nkx2-2 NK2 homeobox 2 acts_upstream_of_or_within ISO MGI:1932100 (MGI:3703458|PMID:17202186), (MGI:3768695|PMID:17988662) RGD PMID:17202186 PMID:17988662 MGI:3703458 MGI:3768695 NCBI chr 3:134,619,701...134,630,282 JBrowse link

Term paths to the root
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Term Annotations click to browse term
  biological_process 19492
    developmental process 6768
      cellular developmental process 4473
        cell fate commitment 281
          epithelial cell fate commitment 17
            type B pancreatic cell fate commitment 1
Path 2
Term Annotations click to browse term
  biological_process 19492
    developmental process 6768
      anatomical structure development 6195
        tissue development 2074
          epithelium development 1278
            epithelial cell differentiation 714
              columnar/cuboidal epithelial cell differentiation 105
                glandular epithelial cell differentiation 61
                  enteroendocrine cell differentiation 36
                    type B pancreatic cell differentiation 32
                      type B pancreatic cell fate commitment 1
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