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ONTOLOGY REPORT - ANNOTATIONS


Term:physiological cardiac muscle hypertrophy
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Accession:GO:0003301 term browser browse the term
Definition:The enlargement or overgrowth of all or part of the heart muscle due to an increase in size of cardiac muscle cells without cell division. This process contributes to the developmental growth of the heart.



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cell growth involved in cardiac muscle cell development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adra1a adrenoceptor alpha 1A acts_upstream_of_or_within ISO MGI:104774 (MGI:2664013|PMID:12782680) RGD PMID:12782680 MGI:2664013 NCBI chr15:40,830,125...40,935,902
Ensembl chr15:40,832,534...40,927,500
JBrowse link
G Adra1b adrenoceptor alpha 1B acts_upstream_of_or_within ISO MGI:104773 (MGI:2664013|PMID:12782680) RGD PMID:12782680 MGI:2664013 NCBI chr10:28,255,025...28,373,418
Ensembl chr10:28,255,025...28,312,919
JBrowse link
G Agt angiotensinogen IDA RGD PMID:21376054 RGD:5129173 NCBI chr19:52,529,139...52,549,618
Ensembl chr19:52,529,185...52,540,977
JBrowse link
G Agtr2 angiotensin II receptor, type 2 IMP RGD PMID:21173078 RGD:6903878 NCBI chr  X:112,119,673...112,124,060
Ensembl chr  X:112,120,228...112,124,057
JBrowse link
G Akap13 A-kinase anchoring protein 13 IMP RGD PMID:18951085 RGD:2312638 NCBI chr 1:129,313,183...129,619,647
Ensembl chr 1:129,314,402...129,619,646
JBrowse link
G Ang2 angiogenin, ribonuclease A family, member 2 acts_upstream_of_or_within ISO (MGI:5920524|PMID:29065170) RGD PMID:29065170 MGI:5920524 NCBI chr15:24,398,383...24,415,837
Ensembl chr15:24,398,419...24,398,922
JBrowse link
G Camk2d calcium/calmodulin-dependent protein kinase II delta IMP RGD PMID:21554860 RGD:6907064 NCBI chr 2:215,023,785...215,287,351
Ensembl chr 2:215,024,004...215,286,178
JBrowse link
G Gata4 GATA binding protein 4 IDA RGD PMID:20971938 RGD:5131529 NCBI chr15:37,459,601...37,531,291
Ensembl chr15:37,459,601...37,505,636
JBrowse link
G Gsk3b glycogen synthase kinase 3 beta IDA RGD PMID:27854077 RGD:13792737 NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646
JBrowse link
G Map2k4 mitogen activated protein kinase kinase 4 IMP RGD PMID:9769323 RGD:7495831 NCBI chr10:50,343,227...50,447,956
Ensembl chr10:50,344,915...50,447,993
JBrowse link
G Meis1 Meis homeobox 1 IMP RGD PMID:26597775 RGD:11554891 NCBI chr14:93,155,426...93,294,373
Ensembl chr14:93,155,419...93,294,265
JBrowse link
G Myl2 myosin light chain 2 IEP RGD PMID:7657802 RGD:1580138 NCBI chr12:34,454,223...34,468,554
Ensembl chr12:34,454,218...34,468,983
JBrowse link
G Myocd myocardin IMP RGD PMID:18772130 RGD:5132877 NCBI chr10:49,833,219...49,928,806
Ensembl chr10:49,836,641...49,927,627
JBrowse link
G Nppa natriuretic peptide A IEP RGD PMID:7657802 RGD:1580138 NCBI chr 5:158,429,042...158,430,351
Ensembl chr 5:158,429,042...158,430,351
JBrowse link
G Nppb natriuretic peptide B IEP RGD PMID:7657802 RGD:1580138 NCBI chr 5:158,416,813...158,418,175
Ensembl chr 5:158,416,866...158,418,168
JBrowse link
G Pdlim5 PDZ and LIM domain 5 involved_in IGI PMID:24743145 BHF-UCL PMID:24743145 RGD:10054083 NCBI chr 2:230,952,251...231,120,329
Ensembl chr 2:230,952,248...231,120,275
JBrowse link
G Prkg1 protein kinase cGMP-dependent 1 IMP RGD PMID:19542178 RGD:7775063 NCBI chr 1:228,409,883...229,638,794
Ensembl chr 1:228,408,947...229,639,080
JBrowse link
G Sorbs2 sorbin and SH3 domain containing 2 involved_in IGI PMID:24743145 BHF-UCL PMID:24743145 RGD:10054083 NCBI chr16:46,435,220...46,748,743
Ensembl chr16:46,435,237...46,626,514
JBrowse link
negative regulation of cell growth involved in cardiac muscle cell development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cav3 caveolin 3 IMP RGD PMID:21170593 RGD:6784534 NCBI chr 4:145,582,168...145,598,142
Ensembl chr 4:145,582,060...145,598,137
JBrowse link
G Ctdp1 CTD phosphatase subunit 1 IMP RGD PMID:22569295 RGD:9686371 NCBI chr18:73,854,277...73,916,232
Ensembl chr18:73,854,282...73,916,457
JBrowse link
G Foxp1 forkhead box P1 IMP RGD PMID:26333362 RGD:11561912 NCBI chr 4:131,559,599...132,155,092
Ensembl chr 4:131,564,756...132,112,258
JBrowse link
G G6pd glucose-6-phosphate dehydrogenase IMP RGD PMID:24190878 RGD:10449133 NCBI chr  X:152,201,081...152,220,863
Ensembl chr  X:152,201,098...152,220,801
JBrowse link
G Gsk3a glycogen synthase kinase 3 alpha involved_in ISO (MGI:4829580|PMID:20516643) RGD PMID:20516643 MGI:4829580 NCBI chr 1:80,815,843...80,825,732
Ensembl chr 1:80,815,850...80,825,802
JBrowse link
G Mir451a microRNA 451a IMP RGD PMID:25209900 RGD:11558015 NCBI chr10:62,961,520...62,961,591
Ensembl chr10:62,961,520...62,961,591
JBrowse link
G Pak1 p21 (RAC1) activated kinase 1 IMP RGD PMID:22082674 RGD:11533929 NCBI chr 1:152,111,172...152,226,390
Ensembl chr 1:152,111,188...152,226,383
JBrowse link
G Pi16 peptidase inhibitor 16 acts_upstream_of_or_within ISO (MGI:3810223|PMID:17909105) RGD PMID:17909105 MGI:3810223 NCBI chr20:7,376,073...7,385,386
Ensembl chr20:7,376,126...7,385,383
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha IMP RGD PMID:22198280 RGD:5687133 NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346
JBrowse link
G Rbm10 RNA binding motif protein 10 IMP RGD PMID:30257214 RGD:151667449 NCBI chr  X:1,540,399...1,572,571
Ensembl chr  X:1,540,398...1,572,575
JBrowse link
G Rgs2 regulator of G-protein signaling 2 IMP RGD PMID:16380388 RGD:13524577 NCBI chr13:55,799,749...55,802,354
Ensembl chr13:55,798,829...55,802,385
JBrowse link
G Rgs4 regulator of G-protein signaling 4 IDA RGD PMID:9918533 RGD:7207376 NCBI chr13:81,936,775...81,943,103
Ensembl chr13:81,936,775...81,943,068
JBrowse link
G Tomm70 translocase of outer mitochondrial membrane 70 IMP RGD PMID:25022898 RGD:13464131 NCBI chr11:43,378,719...43,417,166
Ensembl chr11:43,377,216...43,417,202
JBrowse link
G Yy1 YY1 transcription factor IMP RGD PMID:18632988 RGD:9588273 NCBI chr 6:127,706,739...127,731,907
Ensembl chr 6:127,707,596...127,732,747
JBrowse link
G Zfp418 zinc finger protein 418 acts_upstream_of_or_within ISO (MGI:5920524|PMID:29065170) RGD PMID:29065170 MGI:5920524 NCBI chr 1:66,581,406...66,594,247
Ensembl chr 1:66,581,287...66,594,242
JBrowse link
positive regulation of cell growth involved in cardiac muscle cell development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adrb1 adrenoceptor beta 1 IMP RGD PMID:18194989 RGD:5129139 NCBI chr 1:255,772,217...255,773,617
Ensembl chr 1:255,771,597...255,807,259
JBrowse link
G Akap6 A-kinase anchoring protein 6 IMP
IDA
RGD PMID:21550986 PMID:16306226 RGD:6902940, RGD:2312613 NCBI chr 6:70,184,101...70,624,369
Ensembl chr 6:70,184,175...70,619,738
JBrowse link
G Ccn4 cellular communication network factor 4 IMP RGD PMID:21376054 RGD:5129173 NCBI chr 7:98,645,238...98,677,253
Ensembl chr 7:98,645,182...98,677,248
JBrowse link
G Ddx39b DExD-box helicase 39B IMP RGD PMID:20116367 RGD:10401141 NCBI chr20:3,547,702...3,585,064
Ensembl chr20:3,572,056...3,584,996
JBrowse link
G Edn1 endothelin 1 involved_in ISO RNAcentral:URS000006FDD4_9606|RNAcentral:URS000013D17D_9606 (PMID:24117217) RGD PMID:24117217 NCBI chr17:22,454,924...22,460,812
Ensembl chr17:22,454,420...22,460,885
JBrowse link
G Ep300 E1A binding protein p300 IMP RGD PMID:12724418 RGD:2312280 NCBI chr 7:113,108,476...113,178,529
Ensembl chr 7:113,106,247...113,136,088
Ensembl chr 7:113,106,247...113,136,088
JBrowse link
G Fdps farnesyl diphosphate synthase IMP RGD PMID:19716825 RGD:2316294 NCBI chr 2:174,497,402...174,507,031
Ensembl chr 2:174,486,665...174,507,776
JBrowse link
G Hamp hepcidin antimicrobial peptide IMP RGD PMID:24424338 RGD:11041632 NCBI chr 1:86,170,926...86,172,865
Ensembl chr 1:86,170,901...86,172,891
JBrowse link
G Igf1 insulin-like growth factor 1 involved_in ISO
IEA
RNAcentral:URS000006FDD4_9606|RNAcentral:URS000013D17D_9606 (PMID:24117217)
GO_REF:0000107
RGD
Ensembl
PMID:24117217 GO_REF:0000107 NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296
JBrowse link
G Mir19a microRNA 19a involved_in ISO UniProtKB:P05019 (PMID:24117217) RGD PMID:24117217 NCBI chr15:92,180,912...92,180,993
Ensembl chr15:92,180,912...92,180,993
JBrowse link
G Mir19b1 microRNA 19b-1 involved_in ISO UniProtKB:P05019 (PMID:24117217) RGD PMID:24117217 NCBI chr15:92,181,214...92,181,300
Ensembl chr15:92,181,214...92,181,300
JBrowse link
G Mir19b2 microRNA 19b-2 involved_in ISO UniProtKB:P05019 (PMID:24117217) RGD PMID:24117217 NCBI chr  X:132,422,072...132,422,167
Ensembl chr  X:132,422,072...132,422,167
JBrowse link
G Mtor mechanistic target of rapamycin kinase IMP RGD PMID:21318349 PMID:21933187 RGD:10040977, RGD:10040978 NCBI chr 5:158,884,856...158,994,311
Ensembl chr 5:158,884,804...158,994,311
JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 IMP RGD PMID:22989630 RGD:7174736 NCBI chr18:31,271,681...31,393,320
Ensembl chr18:31,271,681...31,393,375
JBrowse link
G Parp2 poly (ADP-ribose) polymerase 2 IMP RGD PMID:23261455 RGD:13514044 NCBI chr15:24,034,069...24,044,340
Ensembl chr15:24,034,106...24,044,338
JBrowse link
G Pin1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 IMP RGD PMID:23487407 RGD:8693424 NCBI chr 8:19,189,408...19,200,785
Ensembl chr 8:19,189,373...19,200,785
JBrowse link
G Sirt1 sirtuin 1 IMP RGD PMID:25281201 RGD:13514043 NCBI chr20:25,307,143...25,329,260
Ensembl chr20:25,306,917...25,329,260
JBrowse link
G Slc25a4 solute carrier family 25 member 4 IDA RGD PMID:21325829 RGD:9681466 NCBI chr16:46,072,935...46,076,730
Ensembl chr16:46,072,939...46,076,733
JBrowse link
G Trip10 thyroid hormone receptor interactor 10 IMP RGD PMID:23915320 RGD:11535145 NCBI chr 9:2,133,085...2,147,795
Ensembl chr 9:2,133,671...2,147,799
JBrowse link
regulation of cell growth involved in cardiac muscle cell development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Col14a1 collagen type XIV alpha 1 chain acts_upstream_of_or_within ISO MGI:3846440 (MGI:5444801|PMID:22906538) RGD PMID:22906538 MGI:5444801 NCBI chr 7:86,722,093...86,937,215
Ensembl chr 7:86,722,094...86,937,214
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20026
    developmental process 7035
      developmental growth 869
        cardiac muscle tissue growth 124
          physiological cardiac muscle hypertrophy 53
            cell growth involved in cardiac muscle cell development + 53
Path 2
Term Annotations click to browse term
  biological_process 20026
    developmental process 7035
      anatomical structure development 6470
        multicellular organism development 5243
          system development 4501
            circulatory system development 1333
              heart development 720
                heart growth 135
                  cardiac muscle tissue growth 124
                    physiological cardiac muscle hypertrophy 53
                      cell growth involved in cardiac muscle cell development + 53
paths to the root