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ONTOLOGY REPORT - ANNOTATIONS


Term:endocardial cushion formation
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Accession:GO:0003272 term browser browse the term
Definition:The developmental process pertaining to the initial formation of an endocardial cushion. The endocardial cushion is a specialized region of mesenchymal cells that will give rise to the heart septa and valves.


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endocardial cushion formation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bmp5 bone morphogenetic protein 5 JBrowse link 9 75,775,365 75,900,316 RGD:2290270
G Bmp7 bone morphogenetic protein 7 JBrowse link 2 172,868,012 172,940,321 RGD:2290270
G Bmpr1a bone morphogenetic protein receptor, type 1A JBrowse link 14 34,411,061 34,503,336 RGD:2290270
G Robo1 roundabout guidance receptor 1 JBrowse link 16 72,027,518 73,047,491 RGD:2290270
G Robo2 roundabout guidance receptor 2 JBrowse link 16 73,891,976 75,447,443 RGD:2290270
G Tbx20 T-box 20 JBrowse link 9 24,720,812 24,774,303 RGD:2290270
cell migration involved in endocardial cushion formation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Dchs1 dachsous cadherin related 1 JBrowse link 7 105,752,989 105,788,355 RGD:2290270
G Eng endoglin JBrowse link 2 32,646,595 32,682,669 RGD:2290270
G Notch1 notch 1 JBrowse link 2 26,457,902 26,503,822 RGD:2290270
G Snai2 snail family zinc finger 2 JBrowse link 16 14,705,852 14,709,395 RGD:2290270
epithelial to mesenchymal transition involved in endocardial cushion formation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bmp4 bone morphogenetic protein 4 JBrowse link 14 46,383,525 46,390,669 RGD:2290270
G Eng endoglin JBrowse link 2 32,646,595 32,682,669 RGD:2290270
G Fgf8 fibroblast growth factor 8 JBrowse link 19 45,736,798 45,742,941 RGD:2290270
G Hey1 hairy/enhancer-of-split related with YRPW motif 1 JBrowse link 3 8,663,359 8,667,038 RGD:2290270
G Heyl hairy/enhancer-of-split related with YRPW motif-like JBrowse link 4 123,233,556 123,249,870 RGD:2290270
G Msx1 msh homeobox 1 JBrowse link 5 37,820,491 37,824,585 RGD:2290270
G Msx2 msh homeobox 2 JBrowse link 13 53,466,881 53,472,780 RGD:2290270
G Notch1 notch 1 JBrowse link 2 26,457,902 26,503,822 RGD:2290270
G Rbpj recombination signal binding protein for immunoglobulin kappa J region JBrowse link 5 53,555,779 53,657,445 RGD:2290270
G Smad4 SMAD family member 4 JBrowse link 18 73,634,790 73,703,791 RGD:2290270
G Snai1 snail family zinc finger 1 JBrowse link 2 167,538,195 167,542,814 RGD:2290270
G Snai2 snail family zinc finger 2 JBrowse link 16 14,705,852 14,709,395 RGD:2290270
G Tmem100 transmembrane protein 100 JBrowse link 11 90,030,348 90,036,508 RGD:2290270
negative regulation of epithelial to mesenchymal transition involved in endocardial cushion formation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Nog noggin JBrowse link 11 89,300,638 89,302,559 RGD:2290270
G Tgfb2 transforming growth factor, beta 2 JBrowse link 1 186,622,787 186,709,697 RGD:2290270
positive regulation of epithelial to mesenchymal transition involved in endocardial cushion formation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Acvr1 activin A receptor, type 1 JBrowse link 2 58,446,438 58,566,828 RGD:2290270
G Eng endoglin JBrowse link 2 32,646,595 32,682,669 RGD:2290270
G Tgfb2 transforming growth factor, beta 2 JBrowse link 1 186,622,787 186,709,697 RGD:2290270
G Tgfbr1 transforming growth factor, beta receptor I JBrowse link 4 47,353,222 47,414,926 RGD:2290270
G Tgfbr2 transforming growth factor, beta receptor II JBrowse link 9 116,087,695 116,175,363 RGD:2290270
regulation of epithelial to mesenchymal transition involved in endocardial cushion formation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Tgfb1 transforming growth factor, beta 1 JBrowse link 7 25,687,002 25,705,077 RGD:2290270
G Tgfb3 transforming growth factor, beta 3 JBrowse link 12 86,056,743 86,079,041 RGD:2290270

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 23017
    developmental process 6306
      anatomical structure formation involved in morphogenesis 1161
        endocardial cushion formation 27
          cell migration involved in endocardial cushion formation 4
          epithelial to mesenchymal transition involved in endocardial cushion formation + 20
Path 2
Term Annotations click to browse term
  biological_process 23017
    developmental process 6306
      anatomical structure development 5847
        multicellular organism development 5339
          system development 4730
            animal organ development 3480
              mesenchyme development 270
                endocardial cushion development 49
                  endocardial cushion morphogenesis 37
                    endocardial cushion formation 27
                      cell migration involved in endocardial cushion formation 4
                      epithelial to mesenchymal transition involved in endocardial cushion formation + 20
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.