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ONTOLOGY REPORT - ANNOTATIONS

Term:regulation of membrane depolarization
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Accession:GO:0003254 term browser browse the term
Definition:Any process that modulates the rate, frequency or extent of membrane depolarization. Membrane depolarization is the process in which membrane potential changes in the depolarizing direction from the resting potential, usually from negative to positive.

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regulation of membrane depolarization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G B2m beta-2-microglobulin involved_in ISO (PMID:23144825) UniProt PMID:23144825 NCBI chrNW_004936471:7,646,504...7,655,656 JBrowse link
G Camk2d calcium/calmodulin dependent protein kinase II delta involved_in ISO (PMID:22514276) BHF-UCL PMID:22514276 NCBI chrNW_004936563:4,226,412...4,526,139 JBrowse link
G Cftr CF transmembrane conductance regulator NOT|involved_in ISO (MGI:5640937|PMID:24885604) UniProt PMID:24885604 MGI:5640937 NCBI chrNW_004936589:1,565,933...1,719,208 JBrowse link
G Fgf12 fibroblast growth factor 12 involved_in ISO PMID:12401812 BHF-UCL PMID:12401812 RGD:6484231 NCBI chrNW_004936711:1,873,030...2,378,028 JBrowse link
G Fhl1 four and a half LIM domains 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936513:11,025,753...11,064,312 JBrowse link
G Hcn1 hyperpolarization activated cyclic nucleotide gated potassium channel 1 involved_in ISO
IEA		 RGD
Ensembl		 PMID:20806410 GO_REF:0000107 RGD:9686372 NCBI chrNW_004936480:17,051,902...17,416,335 JBrowse link
G Hcn2 hyperpolarization activated cyclic nucleotide gated potassium and sodium channel 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936588:202,101...209,255 JBrowse link
G Hcn3 hyperpolarization activated cyclic nucleotide gated potassium channel 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936580:4,760,289...4,770,571 JBrowse link
G Hcn4 hyperpolarization activated cyclic nucleotide gated potassium channel 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936471:32,527,551...32,570,548 JBrowse link
G Nedd4l NEDD4 like E3 ubiquitin protein ligase involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936497:6,106,284...6,318,339 JBrowse link
G Npff neuropeptide FF-amide peptide precursor ISO RGD PMID:17289819 RGD:2316567 NCBI chrNW_004936512:10,780,277...10,782,219 JBrowse link
G Ntsr1 neurotensin receptor 1 ISO RGD PMID:15120846 RGD:9743930 NCBI chrNW_004936514:10,240,990...10,272,859 JBrowse link
G Rangrf RAN guanine nucleotide release factor involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936595:1,513,855...1,515,300 JBrowse link
negative regulation of membrane depolarization during cardiac muscle cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cav3 caveolin 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936602:4,264,896...4,278,160 JBrowse link
negative regulation of mitochondrial depolarization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bok BCL2 family apoptosis regulator BOK involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936745:344,837...350,950 JBrowse link
G Got1 glutamic-oxaloacetic transaminase 1 ISO RGD PMID:29215467 RGD:13504824 NCBI chrNW_004936636:617,376...640,424 JBrowse link
G Hsh2d hematopoietic SH2 domain containing acts_upstream_of_or_within ISO (MGI:3574118|PMID:15569688) MGI PMID:15569688 MGI:3574118 NCBI chrNW_004936596:4,371,480...4,376,985 JBrowse link
G Ngfr nerve growth factor receptor ISO RGD PMID:19457114 RGD:5508731 NCBI chrNW_004936490:12,038,500...12,057,257 JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936561:3,826,802...3,844,406 JBrowse link
positive regulation of membrane depolarization during cardiac muscle cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ank3 ankyrin 3 involved_in ISO PMID:18180363 BHF-UCL PMID:18180363 RGD:6767295 NCBI chrNW_004936614:2,664,594...2,976,174 JBrowse link
positive regulation of mitochondrial depolarization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cck cholecystokinin ISO apoptotic RGD PMID:11964411 RGD:625521 NCBI chrNW_004936695:2,776,705...2,782,280 JBrowse link
G Dcn decorin acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:23798385) MGI
Ensembl		 PMID:23798385 GO_REF:0000107 NCBI chrNW_004936507:7,887,259...7,923,055 JBrowse link
G Kdr kinase insert domain receptor acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:23798385) MGI
Ensembl		 PMID:23798385 GO_REF:0000107 NCBI chrNW_004936482:17,537,697...17,581,320 JBrowse link
G Mllt11 MLLT11 transcription factor 7 cofactor involved_in ISO (PMID:18852119) UniProt PMID:18852119 NCBI chrNW_004936580:1,274,658...1,283,505 JBrowse link
G Myoc myocilin involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936481:15,544,733...15,556,813 JBrowse link
G Oga O-GlcNAcase ISO RGD PMID:19139380 RGD:2305938 NCBI chrNW_004936600:3,983,983...3,996,360 JBrowse link
G P2rx7 purinergic receptor P2X 7 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:3607437|PMID:16198349) MGI
Ensembl		 PMID:16198349 GO_REF:0000107 MGI:3607437 NCBI chrNW_004936558:3,106,819...3,149,689 JBrowse link
G Parp1 poly(ADP-ribose) polymerase 1 ISO protein:increased activity:brain: RGD PMID:21616968 RGD:10413888 NCBI chrNW_004936526:3,102,468...3,147,601 JBrowse link
G Rack1 receptor for activated C kinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936826:748,256...753,460 JBrowse link
G Tspo translocator protein ISO RGD PMID:15183124 RGD:2317155 NCBI chrNW_004936718:992,301...995,172 JBrowse link
positive regulation of regulation of vascular associated smooth muscle cell membrane depolarization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Trpm4 transient receptor potential cation channel subfamily M member 4 ISO RGD PMID:20826763 RGD:10003037 NCBI chrNW_004936664:3,093,258...3,124,473 JBrowse link
regulation of atrial cardiac muscle cell membrane depolarization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cacna1g calcium voltage-gated channel subunit alpha1 G acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:3714901|PMID:16690884) MGI
Ensembl		 PMID:16690884 GO_REF:0000107 MGI:3714901 NCBI chrNW_004936490:11,093,600...11,157,756 JBrowse link
G Gja1 gap junction protein alpha 1 acts_upstream_of_or_within ISO (MGI:3639795|PMID:10969038) MGI PMID:10969038 MGI:3639795 NCBI chrNW_004936658:3,920,043...3,932,987 JBrowse link
G Gja5 gap junction protein alpha 5 involved_in
acts_upstream_of_or_within		 ISO (PMID:22247482), (PMID:23348765)
(MGI:1197846|PMID:9501070), (MGI:3639795|PMID:10969038), (MGI:3696497|PMID:10515563)		 BHF-UCL
MGI		 PMID:9501070 PMID:10515563 PMID:10969038 PMID:22247482 PMID:23348765 MGI:1197846 MGI:3639795 MGI:3696497 NCBI chrNW_004936867:269,477...279,549 JBrowse link
G Scn10a sodium voltage-gated channel alpha subunit 10 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:4848026|PMID:20062061) MGI
Ensembl		 PMID:20062061 GO_REF:0000107 MGI:4848026 NCBI chrNW_004936473:28,010,123...28,102,124 JBrowse link
G Scn1b sodium voltage-gated channel beta subunit 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936570:1,187,916...1,195,423 JBrowse link
G Scn2b sodium voltage-gated channel beta subunit 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936542:3,262,161...3,274,545 JBrowse link
G Scn3b sodium voltage-gated channel beta subunit 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936542:8,082,487...8,106,154 JBrowse link
G Scn5a sodium voltage-gated channel alpha subunit 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936473:27,883,526...27,963,994 JBrowse link
G Tbx5 T-box transcription factor 5 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:5449667|PMID:22728936) BHF-UCL
Ensembl		 PMID:22728936 GO_REF:0000107 MGI:5449667 NCBI chrNW_004936558:7,408,229...7,454,897 JBrowse link
regulation of membrane depolarization during action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ptpn3 protein tyrosine phosphatase non-receptor type 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936559:3,436,114...3,547,316 JBrowse link
regulation of membrane depolarization during cardiac muscle cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cav3 caveolin 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936602:4,264,896...4,278,160 JBrowse link
G Gja5 gap junction protein alpha 5 acts_upstream_of_or_within ISO (MGI:1197846|PMID:9501070) MGI PMID:9501070 MGI:1197846 NCBI chrNW_004936867:269,477...279,549 JBrowse link
G LOC101964904 sarcolemma associated protein involved_in ISO (PMID:23064965) BHF-UCL PMID:23064965 NCBI chrNW_004936473:8,057,236...8,208,564 JBrowse link
G Rangrf RAN guanine nucleotide release factor involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936595:1,513,855...1,515,300 JBrowse link
regulation of mitochondrial depolarization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcd1 ATP binding cassette subfamily D member 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936809:615,133...634,618 JBrowse link
G Gclc glutamate-cysteine ligase catalytic subunit acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:3047441|PMID:15288121) MGI
Ensembl		 PMID:15288121 GO_REF:0000107 MGI:3047441 NCBI chrNW_004936476:7,371,270...7,418,756 JBrowse link
G LOC101977655 glutamate--cysteine ligase regulatory subunit acts_upstream_of_or_within ISO (MGI:3047441|PMID:15288121) MGI PMID:15288121 MGI:3047441 NCBI chrNW_004936537:5,356,914...5,378,998 JBrowse link
G Lrrk2 leucine rich repeat kinase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936607:628,469...761,117 JBrowse link
G Ppp2r3c protein phosphatase 2 regulatory subunit B''gamma acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:3589325|PMID:16129705) MGI
Ensembl		 PMID:16129705 GO_REF:0000107 MGI:3589325 NCBI chrNW_004936494:9,247,600...9,283,019 JBrowse link
regulation of ventricular cardiac muscle cell membrane depolarization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cav3 caveolin 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936602:4,264,896...4,278,160 JBrowse link
G Gja1 gap junction protein alpha 1 acts_upstream_of_or_within ISO (MGI:3639795|PMID:10969038)
(MGI:3639795|PMID:10969038), (MGI:86953|PMID:9109444)		 MGI PMID:9109444 PMID:10969038 MGI:3639795 MGI:86953 NCBI chrNW_004936658:3,920,043...3,932,987 JBrowse link
G Gja5 gap junction protein alpha 5 acts_upstream_of_or_within ISO (MGI:1197846|PMID:9501070), (MGI:3696497|PMID:10515563)
(MGI:6101691|PMID:26786475)
(MGI:3639795|PMID:10969038)		 MGI
BHF-UCL		 PMID:9501070 PMID:10515563 PMID:10969038 PMID:26786475 MGI:1197846 MGI:3639795 MGI:3696497 MGI:6101691 NCBI chrNW_004936867:269,477...279,549 JBrowse link
G Gpd1l glycerol-3-phosphate dehydrogenase 1 like involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936473:22,649,107...22,774,719 JBrowse link
G Scn3b sodium voltage-gated channel beta subunit 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936542:8,082,487...8,106,154 JBrowse link
G Scn5a sodium voltage-gated channel alpha subunit 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936473:27,883,526...27,963,994 JBrowse link
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