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ONTOLOGY REPORT - ANNOTATIONS

Term:regulation of membrane depolarization
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Accession:GO:0003254 term browser browse the term
Definition:Any process that modulates the rate, frequency or extent of membrane depolarization. Membrane depolarization is the process in which membrane potential changes in the depolarizing direction from the resting potential, usually from negative to positive.


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regulation of membrane depolarization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G B2m beta-2 microglobulin involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 2:121,978,168...121,983,563
Ensembl chr 2:121,978,167...121,983,564 		JBrowse link
G Camk2d calcium/calmodulin-dependent protein kinase II, delta involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 3:126,389,136...126,639,975
Ensembl chr 3:126,389,951...126,639,975 		JBrowse link
G Cftr cystic fibrosis transmembrane conductance regulator NOT|involved_in IMP (MGI:5640937|PMID:24885604) UniProt PMID:24885604 MGI:5640937 NCBI chr 6:18,170,686...18,322,769
Ensembl chr 6:18,170,686...18,322,767 		JBrowse link
G Fgf12 fibroblast growth factor 12 involved_in ISO MGI GO_REF:0000096 MGI:4417868 NCBI chr16:27,976,535...28,571,995
Ensembl chr16:27,978,850...28,571,820 		JBrowse link
G Fhl1 four and a half LIM domains 1 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr  X:55,776,569...55,838,704
Ensembl chr  X:55,777,147...55,838,706 		JBrowse link
G Hcn1 hyperpolarization activated cyclic nucleotide gated potassium channel 1 involved_in ISO
IBA		 RGD
GO_Central
MGI		 PMID:20806410 GO_REF:0000033 GO_REF:0000096 MGI:4417868 RGD:9686372 NCBI chr13:117,738,856...118,117,564
Ensembl chr13:117,738,856...118,123,954 		JBrowse link
G Hcn2 hyperpolarization-activated, cyclic nucleotide-gated K+ 2 involved_in IBA GO_Central GO_REF:0000033 NCBI chr10:79,552,468...79,571,942
Ensembl chr10:79,552,468...79,571,942 		JBrowse link
G Hcn3 hyperpolarization-activated, cyclic nucleotide-gated K+ 3 involved_in IBA GO_Central GO_REF:0000033 NCBI chr 3:89,054,082...89,067,538
Ensembl chr 3:89,053,381...89,067,503 		JBrowse link
G Hcn4 hyperpolarization-activated, cyclic nucleotide-gated K+ 4 involved_in ISO
IBA		 MGI
GO_Central		 GO_REF:0000033 GO_REF:0000119 MGI:4834177 NCBI chr 9:58,730,232...58,770,458
Ensembl chr 9:58,730,695...58,770,458 		JBrowse link
G Nedd4l neural precursor cell expressed, developmentally down-regulated gene 4-like involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr18:65,017,551...65,350,888
Ensembl chr18:65,020,776...65,350,899 		JBrowse link
G Npff neuropeptide FF-amide peptide precursor involved_in ISO RGD
MGI		 PMID:17289819 GO_REF:0000096 MGI:4417868 RGD:2316567 NCBI chr15:102,432,274...102,433,056
Ensembl chr15:102,432,274...102,433,377 		JBrowse link
G Ntsr1 neurotensin receptor 1 involved_in ISO RGD
MGI		 PMID:15120846 GO_REF:0000096 MGI:4417868 RGD:9743930 NCBI chr 2:180,141,769...180,186,772
Ensembl chr 2:180,141,769...180,186,773 		JBrowse link
G Rangrf RAN guanine nucleotide release factor involved_in IMP
IBA
ISO		 (MGI:5508678|PMID:23420830) BHF-UCL
GO_Central
MGI		 PMID:23420830 GO_REF:0000033 GO_REF:0000119 MGI:4834177 MGI:5508678 NCBI chr11:68,863,310...68,866,011
Ensembl chr11:68,863,310...68,866,011 		JBrowse link
negative regulation of membrane depolarization during cardiac muscle cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cav3 caveolin 3 involved_in IMP (MGI:5613732|PMID:25257915) BHF-UCL PMID:25257915 MGI:5613732 NCBI chr 6:112,436,466...112,449,833
Ensembl chr 6:112,436,466...112,449,833 		JBrowse link
negative regulation of mitochondrial depolarization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alb albumin involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 5:90,608,729...90,624,461
Ensembl chr 5:90,608,756...90,624,461 		JBrowse link
G Bok BCL2-related ovarian killer involved_in IMP (MGI:5796062|PMID:27098698) UniProt PMID:27098698 MGI:5796062 NCBI chr 1:93,613,297...93,623,492
Ensembl chr 1:93,613,382...93,623,486 		JBrowse link
G Got1 glutamic-oxaloacetic transaminase 1, soluble involved_in ISO RGD
MGI		 PMID:29215467 GO_REF:0000096 MGI:4417868 RGD:13504824 NCBI chr19:43,488,191...43,514,743
Ensembl chr19:43,488,191...43,513,044 		JBrowse link
G Hsh2d hematopoietic SH2 domain containing acts_upstream_of_or_within IDA (PMID:15569688) MGI PMID:15569688 NCBI chr 8:72,943,512...72,954,802
Ensembl chr 8:72,943,482...72,955,371 		JBrowse link
G Ngfr nerve growth factor receptor (TNFR superfamily, member 16) involved_in ISO RGD
MGI		 PMID:19457114 GO_REF:0000096 MGI:4417868 RGD:5508731 NCBI chr11:95,459,644...95,478,524
Ensembl chr11:95,459,644...95,478,561 		JBrowse link
G Rbfox2 RNA binding protein, fox-1 homolog (C. elegans) 2 involved_in ISO RGD
MGI		 PMID:34731606 GO_REF:0000096 MGI:4417868 RGD:329845875 NCBI chr15:76,963,190...77,193,058
Ensembl chr15:76,963,190...77,191,204 		JBrowse link
G Src Rous sarcoma oncogene involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 2:157,265,828...157,313,758
Ensembl chr 2:157,260,364...157,313,782 		JBrowse link
positive regulation of membrane depolarization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cacna1c calcium channel, voltage-dependent, L type, alpha 1C subunit involved_in ISO RGD
MGI		 PMID:18562674 GO_REF:0000096 MGI:4417868 RGD:152177517 NCBI chr 6:118,564,201...119,174,345
Ensembl chr 6:118,564,201...119,173,851 		JBrowse link
G Cacna1d calcium channel, voltage-dependent, L type, alpha 1D subunit involved_in ISO RGD
MGI		 PMID:7760845 GO_REF:0000096 MGI:4417868 RGD:70680 NCBI chr14:29,761,898...30,213,113
Ensembl chr14:29,761,896...30,213,412 		JBrowse link
G Creb1 cAMP responsive element binding protein 1 ISO RGD PMID:16641242 RGD:401959318 NCBI chr 1:64,571,963...64,643,707
Ensembl chr 1:64,571,804...64,643,707 		JBrowse link
positive regulation of membrane depolarization during cardiac muscle cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ank3 ankyrin 3, epithelial involved_in ISO MGI GO_REF:0000096 MGI:4417868 NCBI chr10:69,234,608...69,863,266
Ensembl chr10:69,234,603...69,863,268 		JBrowse link
positive regulation of mitochondrial depolarization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adcy10 adenylate cyclase 10 involved_in ISO RGD
MGI		 PMID:31172217 GO_REF:0000096 MGI:4417868 RGD:329403053 NCBI chr 1:165,309,114...165,404,347
Ensembl chr 1:165,312,752...165,404,343 		JBrowse link
G Alox12 arachidonate 12-lipoxygenase involved_in ISO RGD
MGI		 PMID:15564577 GO_REF:0000096 MGI:4417868 RGD:2313870 NCBI chr11:70,132,283...70,146,206
Ensembl chr11:70,132,283...70,146,179 		JBrowse link
G Cck cholecystokinin involved_in ISO apoptotic RGD
MGI		 PMID:11964411 GO_REF:0000096 MGI:4417868 RGD:625521 NCBI chr 9:121,318,890...121,324,728
Ensembl chr 9:121,318,890...121,324,760 		JBrowse link
G Dcn decorin acts_upstream_of_or_within ISO MGI GO_REF:0000008 NCBI chr10:97,315,362...97,354,025
Ensembl chr10:97,315,471...97,354,005 		JBrowse link
G Kdr kinase insert domain protein receptor acts_upstream_of_or_within ISO MGI GO_REF:0000008 NCBI chr 5:76,093,487...76,139,880
Ensembl chr 5:76,093,487...76,139,118 		JBrowse link
G Mllt11 myeloid/lymphoid or mixed-lineage leukemia; translocated to, 11 involved_in ISO
IBA		 MGI
GO_Central		 GO_REF:0000033 GO_REF:0000119 MGI:4834177 NCBI chr 3:95,125,852...95,139,486
Ensembl chr 3:95,126,446...95,139,482 		JBrowse link
G Myoc myocilin involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 1:162,466,719...162,477,263
Ensembl chr 1:162,466,724...162,477,262 		JBrowse link
G Oga O-GlcNAcase involved_in ISO RGD
MGI		 PMID:19139380 GO_REF:0000096 MGI:4417868 RGD:2305938 NCBI chr19:45,738,698...45,772,274
Ensembl chr19:45,738,698...45,772,276 		JBrowse link
G P2rx7 purinergic receptor P2X, ligand-gated ion channel, 7 acts_upstream_of_or_within IMP (PMID:16198349) MGI PMID:16198349 NCBI chr 5:122,781,990...122,830,399
Ensembl chr 5:122,781,974...122,829,495 		JBrowse link
G Parp1 poly (ADP-ribose) polymerase family, member 1 involved_in ISO protein:increased activity:brain: RGD
MGI		 PMID:21616968 GO_REF:0000096 MGI:4417868 RGD:10413888 NCBI chr 1:180,396,456...180,428,564
Ensembl chr 1:180,396,489...180,428,819 		JBrowse link
G Rack1 receptor for activated C kinase 1 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr11:48,691,187...48,697,068
Ensembl chr11:48,691,159...48,697,261 		JBrowse link
G Tspo translocator protein involved_in ISO RGD
MGI		 PMID:15183124 GO_REF:0000096 MGI:4417868 RGD:2317155 NCBI chr15:83,447,774...83,458,404
Ensembl chr15:83,447,793...83,458,404 		JBrowse link
positive regulation of regulation of vascular associated smooth muscle cell membrane depolarization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Trpm4 transient receptor potential cation channel, subfamily M, member 4 involved_in ISO RGD
MGI		 PMID:20826763 GO_REF:0000096 MGI:4417868 RGD:10003037 NCBI chr 7:44,952,579...44,983,495
Ensembl chr 7:44,952,056...44,983,204 		JBrowse link
regulation of atrial cardiac muscle cell membrane depolarization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cacna1g calcium channel, voltage-dependent, T type, alpha 1G subunit acts_upstream_of_or_within IMP (PMID:16690884) MGI PMID:16690884 NCBI chr11:94,299,217...94,365,226
Ensembl chr11:94,299,217...94,365,024 		JBrowse link
G Gja1 gap junction protein, alpha 1 acts_upstream_of_or_within IMP (PMID:10969038) MGI PMID:10969038 NCBI chr10:56,253,297...56,266,519
Ensembl chr10:56,253,426...56,278,609 		JBrowse link
G Gja5 gap junction protein, alpha 5 involved_in
acts_upstream_of_or_within		 ISO
IMP		 (PMID:10515563), (PMID:10969038), (PMID:9501070) MGI PMID:9501070 PMID:10515563 PMID:10969038 GO_REF:0000119 MGI:4834177 NCBI chr 3:96,939,718...96,960,950
Ensembl chr 3:96,812,009...96,984,732 		JBrowse link
G Scn10a sodium channel, voltage-gated, type X, alpha involved_in
acts_upstream_of_or_within		 ISO
IBA
IMP		 (PMID:20062061) MGI
GO_Central		 PMID:20062061 GO_REF:0000033 GO_REF:0000119 MGI:4834177 NCBI chr 9:119,437,522...119,548,388
Ensembl chr 9:119,437,522...119,548,388 		JBrowse link
G Scn1b sodium channel, voltage-gated, type I, beta involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 7:30,815,949...30,826,436
Ensembl chr 7:30,815,949...30,826,428 		JBrowse link
G Scn2b sodium channel, voltage-gated, type II, beta involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 9:45,029,174...45,041,368
Ensembl chr 9:45,029,080...45,041,368 		JBrowse link
G Scn3b sodium channel, voltage-gated, type III, beta involved_in IMP
ISO		 (MGI:5294533|PMID:19796257) BHF-UCL
MGI		 PMID:19796257 GO_REF:0000119 MGI:4834177 MGI:5294533 NCBI chr 9:40,180,512...40,202,914
Ensembl chr 9:40,180,513...40,202,914 		JBrowse link
G Scn5a sodium channel, voltage-gated, type V, alpha involved_in ISO
IBA		 MGI
GO_Central		 GO_REF:0000033 GO_REF:0000119 MGI:4834177 NCBI chr 9:119,312,470...119,408,096
Ensembl chr 9:119,312,474...119,408,082 		JBrowse link
G Tbx5 T-box 5 acts_upstream_of_positive_effect IGI (MGI:5449667|PMID:22728936) BHF-UCL PMID:22728936 MGI:5449667 NCBI chr 5:119,934,581...120,023,285
Ensembl chr 5:119,970,733...120,023,284 		JBrowse link
regulation of membrane depolarization during action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ptpn3 protein tyrosine phosphatase, non-receptor type 3 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 4:57,190,841...57,339,036
Ensembl chr 4:57,190,841...57,301,837 		JBrowse link
regulation of membrane depolarization during cardiac muscle cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cav3 caveolin 3 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 6:112,436,466...112,449,833
Ensembl chr 6:112,436,466...112,449,833 		JBrowse link
G Gja5 gap junction protein, alpha 5 acts_upstream_of_or_within IMP (PMID:9501070) MGI PMID:9501070 NCBI chr 3:96,939,718...96,960,950
Ensembl chr 3:96,812,009...96,984,732 		JBrowse link
G Rangrf RAN guanine nucleotide release factor involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr11:68,863,310...68,866,011
Ensembl chr11:68,863,310...68,866,011 		JBrowse link
G Slmap sarcolemma associated protein involved_in ISO
IBA		 MGI
GO_Central		 GO_REF:0000033 GO_REF:0000119 MGI:4834177 NCBI chr14:26,134,323...26,256,103
Ensembl chr14:26,134,323...26,256,086 		JBrowse link
regulation of mitochondrial depolarization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcd1 ATP-binding cassette, sub-family D member 1 involved_in IMP (MGI:5790173|PMID:25583114) UniProt PMID:25583114 MGI:5790173 NCBI chr  X:72,760,203...72,782,140
Ensembl chr  X:72,760,203...72,782,140 		JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit acts_upstream_of_or_within IGI (PMID:15288121) MGI PMID:15288121 NCBI chr 9:77,661,817...77,701,771
Ensembl chr 9:77,661,817...77,701,767 		JBrowse link
G Gclm glutamate-cysteine ligase, modifier subunit acts_upstream_of_or_within IGI (PMID:15288121) MGI PMID:15288121 NCBI chr 3:122,039,206...122,060,864
Ensembl chr 3:122,039,206...122,064,381 		JBrowse link
G Lrrk2 leucine-rich repeat kinase 2 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr15:91,556,994...91,700,327
Ensembl chr15:91,557,378...91,700,323 		JBrowse link
G Ppp2r3c protein phosphatase 2, regulatory subunit B'', gamma acts_upstream_of_or_within IMP (PMID:16129705) MGI PMID:16129705 NCBI chr12:55,327,594...55,350,024
Ensembl chr12:55,325,776...55,349,783 		JBrowse link
regulation of ventricular cardiac muscle cell membrane depolarization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cav3 caveolin 3 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 6:112,436,466...112,449,833
Ensembl chr 6:112,436,466...112,449,833 		JBrowse link
G Gja1 gap junction protein, alpha 1 acts_upstream_of_or_within IGI
IMP		 (PMID:10969038)
(PMID:10969038), (PMID:9109444)		 MGI PMID:9109444 PMID:10969038 NCBI chr10:56,253,297...56,266,519
Ensembl chr10:56,253,426...56,278,609 		JBrowse link
G Gja5 gap junction protein, alpha 5 acts_upstream_of
acts_upstream_of_or_within		 IMP
IGI		 (MGI:6101691|PMID:26786475)
(PMID:10969038)
(PMID:10515563), (PMID:9501070)		 BHF-UCL
MGI		 PMID:9501070 PMID:10515563 PMID:10969038 PMID:26786475 MGI:6101691 NCBI chr 3:96,939,718...96,960,950
Ensembl chr 3:96,812,009...96,984,732 		JBrowse link
G Gpd1l glycerol-3-phosphate dehydrogenase 1-like involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 9:114,728,407...114,763,055
Ensembl chr 9:114,728,409...114,763,055 		JBrowse link
G Scn3b sodium channel, voltage-gated, type III, beta involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 9:40,180,512...40,202,914
Ensembl chr 9:40,180,513...40,202,914 		JBrowse link
G Scn5a sodium channel, voltage-gated, type V, alpha involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 9:119,312,470...119,408,096
Ensembl chr 9:119,312,474...119,408,082 		JBrowse link
G Smad7 SMAD family member 7 involved_in IC (MGI:3836072|PMID:18952608) BHF-UCL PMID:18952608 MGI:3836072 NCBI chr18:75,500,436...75,529,006
Ensembl chr18:75,500,600...75,529,006 		JBrowse link
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