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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of membrane depolarization
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Accession:GO:0003254 term browser browse the term
Definition:Any process that modulates the rate, frequency or extent of membrane depolarization. Membrane depolarization is the process in which membrane potential changes in the depolarizing direction from the resting potential, usually from negative to positive.



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regulation of membrane depolarization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G B2M beta-2-microglobulin involved_in ISO (PMID:23144825) UniProt PMID:23144825 NCBI chr15:23,668,108...23,674,791
Ensembl chr15:41,836,345...41,842,991
JBrowse link
G CAMK2D calcium/calmodulin dependent protein kinase II delta involved_in ISO (PMID:22514276) BHF-UCL PMID:22514276 NCBI chr 4:105,957,773...106,271,887
Ensembl chr 4:116,523,850...116,835,387
JBrowse link
G CFTR CF transmembrane conductance regulator NOT|involved_in ISO (MGI:5640937|PMID:24885604) UniProt PMID:24885604 MGI:5640937 NCBI chr 7:109,449,847...109,633,023
Ensembl chr 7:122,129,798...122,327,864
JBrowse link
G FGF12 fibroblast growth factor 12 involved_in ISO PMID:12401812 BHF-UCL PMID:12401812 RGD:6484231 NCBI chr 3:189,430,811...190,017,254
Ensembl chr 3:199,778,545...200,358,744
JBrowse link
G FHL1 four and a half LIM domains 1 involved_in ISO (PMID:18281375) BHF-UCL PMID:18281375 NCBI chr  X:125,270,340...125,334,961
Ensembl chr  X:135,559,321...135,602,375
JBrowse link
G HCN1 hyperpolarization activated cyclic nucleotide gated potassium channel 1 involved_in ISO
IEA
RGD
Ensembl
PMID:20806410 GO_REF:0000107 RGD:9686372 NCBI chr 5:64,673,392...65,116,259
Ensembl chr 5:69,724,767...70,158,761
JBrowse link
G HCN2 hyperpolarization activated cyclic nucleotide gated potassium and sodium channel 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:521,348...528,203 JBrowse link
G HCN3 hyperpolarization activated cyclic nucleotide gated potassium channel 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:130,621,991...130,634,402
Ensembl chr 1:134,227,404...134,240,120
JBrowse link
G HCN4 hyperpolarization activated cyclic nucleotide gated potassium channel 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:52,231,906...52,285,220
Ensembl chr15:70,997,020...71,042,285
JBrowse link
G NEDD4L NEDD4 like E3 ubiquitin protein ligase involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:51,428,077...51,792,995
Ensembl chr18:54,867,149...55,123,423
JBrowse link
G NPFF neuropeptide FF-amide peptide precursor ISO RGD PMID:17289819 RGD:2316567 NCBI chr12:35,245,172...35,246,710
Ensembl chr12:36,030,805...36,031,591
JBrowse link
G NTSR1 neurotensin receptor 1 ISO RGD PMID:15120846 RGD:9743930 NCBI chr20:59,100,110...59,151,563
Ensembl chr20:60,392,736...60,446,056
JBrowse link
G RANGRF RAN guanine nucleotide release factor involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:43,369,556...43,371,025
Ensembl chr17:48,101,744...48,103,394
JBrowse link
negative regulation of membrane depolarization during cardiac muscle cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CAV3 caveolin 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:8,684,829...8,697,731
Ensembl chr 3:8,928,069...8,940,942
JBrowse link
negative regulation of mitochondrial depolarization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BOK BCL2 family apoptosis regulator BOK involved_in IEA Ensembl GO_REF:0000107 NCBI chr2B:128,832,458...128,847,918
Ensembl chr2B:247,626,494...247,640,238
JBrowse link
G GOT1 glutamic-oxaloacetic transaminase 1 ISO RGD PMID:29215467 RGD:13504824 NCBI chr10:96,012,345...96,046,266
Ensembl chr10:99,506,205...99,540,178
JBrowse link
G HSH2D hematopoietic SH2 domain containing acts_upstream_of_or_within ISO (MGI:3574118|PMID:15569688) MGI PMID:15569688 MGI:3574118 NCBI chr19:15,629,688...15,643,636
Ensembl chr19:16,611,500...16,624,500
JBrowse link
G IFI6 interferon alpha inducible protein 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:26,929,129...26,935,205
Ensembl chr 1:27,972,866...27,978,890
JBrowse link
G NGFR nerve growth factor receptor ISO RGD PMID:19457114 RGD:5508731 NCBI chr17:8,089,600...8,109,361
Ensembl chr17:8,075,316...8,094,966
JBrowse link
G SRC SRC proto-oncogene, non-receptor tyrosine kinase involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:33,667,614...33,727,126
Ensembl chr20:34,822,271...34,839,634
JBrowse link
positive regulation of membrane depolarization during cardiac muscle cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ANK3 ankyrin 3 involved_in ISO PMID:18180363 BHF-UCL PMID:18180363 RGD:6767295 NCBI chr10:56,560,589...57,269,952
Ensembl chr10:58,790,696...59,602,954
JBrowse link
positive regulation of mitochondrial depolarization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ALOX12 arachidonate 12-lipoxygenase, 12S type ISO RGD PMID:15564577 RGD:2313870 NCBI chr17:7,026,839...7,041,598
Ensembl chr17:7,014,591...7,029,602
JBrowse link
G CCK cholecystokinin ISO apoptotic RGD PMID:11964411 RGD:625521 NCBI chr 3:42,168,012...42,176,358
Ensembl chr 3:42,431,022...42,439,396
JBrowse link
G DCN decorin acts_upstream_of_or_within
involved_in
ISO
IEA
(PMID:23798385) MGI
Ensembl
PMID:23798385 GO_REF:0000107 NCBI chr12:88,678,791...88,715,677
Ensembl chr12:91,994,129...92,031,413
JBrowse link
G KDR kinase insert domain receptor acts_upstream_of_or_within
involved_in
ISO
IEA
(PMID:23798385) MGI
Ensembl
PMID:23798385 GO_REF:0000107 NCBI chr 4:68,813,894...68,861,018
Ensembl chr 4:75,377,375...75,427,109
JBrowse link
G MLLT11 MLLT11 transcription factor 7 cofactor involved_in ISO (PMID:18852119) UniProt PMID:18852119 NCBI chr 1:126,408,533...126,417,624 JBrowse link
G MYOC myocilin involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:147,128,541...147,146,227
Ensembl chr 1:150,841,630...150,858,628
JBrowse link
G OGA O-GlcNAcase ISO RGD PMID:19139380 RGD:2305938 NCBI chr10:98,387,144...98,421,105
Ensembl chr10:101,858,879...101,892,479
JBrowse link
G P2RX7 purinergic receptor P2X 7 acts_upstream_of_or_within ISO (MGI:3607437|PMID:16198349) MGI PMID:16198349 MGI:3607437 NCBI chr12:118,731,761...118,786,039
Ensembl chr12:122,102,888...122,154,068
JBrowse link
G PARP1 poly(ADP-ribose) polymerase 1 ISO protein:increased activity:brain: RGD PMID:21616968 RGD:10413888 NCBI chr 1:201,820,355...201,867,673
Ensembl chr 1:206,812,981...206,860,356
JBrowse link
G RACK1 receptor for activated C kinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:176,462,991...176,470,153
Ensembl chr 5:183,712,665...183,720,128
JBrowse link
G TSPO translocator protein ISO RGD PMID:15183124 RGD:2317155 NCBI chr22:24,034,918...24,046,370
Ensembl chr22:42,233,619...42,244,930
JBrowse link
positive regulation of regulation of vascular associated smooth muscle cell membrane depolarization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TRPM4 transient receptor potential cation channel subfamily M member 4 ISO RGD PMID:20826763 RGD:10003037 NCBI chr19:46,168,301...46,224,726
Ensembl chr19:55,095,029...55,150,464
JBrowse link
regulation of atrial cardiac muscle cell membrane depolarization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GJA1 gap junction protein alpha 1 acts_upstream_of_or_within ISO (MGI:3639795|PMID:10969038) MGI PMID:10969038 MGI:3639795 NCBI chr 6:119,213,513...119,227,617 JBrowse link
G GJA5 gap junction protein alpha 5 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:1197846|PMID:9501070), (MGI:3639795|PMID:10969038), (MGI:3696497|PMID:10515563) MGI
Ensembl
PMID:9501070 PMID:10515563 PMID:10969038 GO_REF:0000107 MGI:1197846 MGI:3639795 MGI:3696497 NCBI chr 1:123,200,111...123,224,626
Ensembl chr 1:112,328,337...112,329,413
JBrowse link
G LOC100983419 voltage-dependent T-type calcium channel subunit alpha-1G acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3714901|PMID:16690884) MGI
Ensembl
PMID:16690884 GO_REF:0000107 MGI:3714901 NCBI chr17:44,654,558...44,786,037
Ensembl chr17:49,529,402...49,595,166
Ensembl chr17:49,529,402...49,595,166
JBrowse link
G SCN10A sodium voltage-gated channel alpha subunit 10 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:4848026|PMID:20062061) MGI
Ensembl
PMID:20062061 GO_REF:0000107 MGI:4848026 NCBI chr 3:38,593,765...38,691,172
Ensembl chr 3:38,876,068...38,972,247
JBrowse link
G SCN1B sodium voltage-gated channel beta subunit 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:31,974,499...31,984,488
Ensembl chr19:40,711,281...40,724,052
JBrowse link
G SCN2B sodium voltage-gated channel beta subunit 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:112,996,609...113,010,412
Ensembl chr11:116,928,676...116,942,500
JBrowse link
G SCN3B sodium voltage-gated channel beta subunit 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:118,460,860...118,486,563
Ensembl chr11:122,377,643...122,403,063
JBrowse link
G SCN5A sodium voltage-gated channel alpha subunit 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:38,444,421...38,546,364
Ensembl chr 3:38,728,897...38,812,202
JBrowse link
G TBX5 T-box transcription factor 5 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:5449667|PMID:22728936) BHF-UCL
Ensembl
PMID:22728936 GO_REF:0000107 MGI:5449667 NCBI chr12:111,954,222...112,009,261
Ensembl chr12:115,333,609...115,389,739
JBrowse link
regulation of membrane depolarization during action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PTPN3 protein tyrosine phosphatase non-receptor type 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:80,528,896...80,651,629
Ensembl chr 9:108,699,761...108,787,464
JBrowse link
regulation of membrane depolarization during cardiac muscle cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CAV3 caveolin 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:8,684,829...8,697,731
Ensembl chr 3:8,928,069...8,940,942
JBrowse link
G GJA5 gap junction protein alpha 5 acts_upstream_of_or_within ISO (MGI:1197846|PMID:9501070) MGI PMID:9501070 MGI:1197846 NCBI chr 1:123,200,111...123,224,626
Ensembl chr 1:112,328,337...112,329,413
JBrowse link
G RANGRF RAN guanine nucleotide release factor involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:43,369,556...43,371,025
Ensembl chr17:48,101,744...48,103,394
JBrowse link
G SLMAP sarcolemma associated protein involved_in ISO (PMID:23064965) BHF-UCL PMID:23064965 NCBI chr 3:57,688,669...57,864,355
Ensembl chr 3:59,108,247...59,280,713
JBrowse link
regulation of mitochondrial depolarization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCD1 ATP binding cassette subfamily D member 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:143,275,165...143,295,283
Ensembl chr  X:153,162,412...153,182,424
JBrowse link
G GCLC glutamate-cysteine ligase catalytic subunit acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3047441|PMID:15288121) MGI
Ensembl
PMID:15288121 GO_REF:0000107 MGI:3047441 NCBI chr 6:53,052,145...53,102,794
Ensembl chr 6:54,687,315...54,734,994
JBrowse link
G GCLM glutamate-cysteine ligase modifier subunit acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3047441|PMID:15288121) MGI
Ensembl
PMID:15288121 GO_REF:0000107 MGI:3047441 NCBI chr 1:96,548,850...96,573,273
Ensembl chr 1:95,278,665...95,297,893
JBrowse link
G LRRK2 leucine rich repeat kinase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:48,343,621...48,488,337
Ensembl chr12:49,205,930...49,350,462
JBrowse link
G PPP2R3C protein phosphatase 2 regulatory subunit B''gamma acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3589325|PMID:16129705) MGI
Ensembl
PMID:16129705 GO_REF:0000107 MGI:3589325 NCBI chr14:15,834,603...15,871,741
Ensembl chr14:34,020,893...34,056,842
JBrowse link
regulation of ventricular cardiac muscle cell membrane depolarization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CAV3 caveolin 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:8,684,829...8,697,731
Ensembl chr 3:8,928,069...8,940,942
JBrowse link
G GJA1 gap junction protein alpha 1 acts_upstream_of_or_within ISO (MGI:3639795|PMID:10969038), (MGI:86953|PMID:9109444) MGI PMID:9109444 PMID:10969038 MGI:3639795 MGI:86953 NCBI chr 6:119,213,513...119,227,617 JBrowse link
G GJA5 gap junction protein alpha 5 acts_upstream_of_or_within ISO (MGI:3639795|PMID:10969038)
(MGI:1197846|PMID:9501070), (MGI:3696497|PMID:10515563)
(MGI:6101691|PMID:26786475)
MGI
BHF-UCL
PMID:9501070 PMID:10515563 PMID:10969038 PMID:26786475 MGI:1197846 MGI:3639795 MGI:3696497 MGI:6101691 NCBI chr 1:123,200,111...123,224,626
Ensembl chr 1:112,328,337...112,329,413
JBrowse link
G GPD1L glycerol-3-phosphate dehydrogenase 1 like involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:32,026,586...32,088,512
Ensembl chr 3:32,342,776...32,404,172
JBrowse link
G SCN3B sodium voltage-gated channel beta subunit 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:118,460,860...118,486,563
Ensembl chr11:122,377,643...122,403,063
JBrowse link
G SCN5A sodium voltage-gated channel alpha subunit 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:38,444,421...38,546,364
Ensembl chr 3:38,728,897...38,812,202
JBrowse link

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