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ONTOLOGY REPORT - ANNOTATIONS

Term:heart valve morphogenesis
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Accession:GO:0003179 term browser browse the term
Definition:The process in which the structure of a heart valve is generated and organized.
Synonyms:narrow_synonym: heart valve remodeling;   heart valve remodelling


show annotations for term's descendants           Sort by:
 
heart valve morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adamts9 ADAM metallopeptidase with thrombospondin type 1 motif, 9 involved_in ISO (MGI:4452308|PMID:20096780) RGD PMID:20096780 MGI:4452308 NCBI chr 4:125,290,633...125,462,988
Ensembl chr 4:125,291,490...125,462,929 		JBrowse link
G Fgfrl1 fibroblast growth factor receptor-like 1 acts_upstream_of_or_within ISO MGI:3849002 (MGI:3848851|PMID:19383940) RGD PMID:19383940 MGI:3848851 NCBI chr14:1,009,863...1,022,620
Ensembl chr14:1,009,786...1,021,928 		JBrowse link
G Mtor mechanistic target of rapamycin kinase acts_upstream_of_or_within ISO MGI:3850506 (MGI:5632243|PMID:25139234) RGD PMID:25139234 MGI:5632243 NCBI chr 5:158,884,856...158,994,311
Ensembl chr 5:158,884,804...158,994,311 		JBrowse link
G Nfatc1 nuclear factor of activated T-cells 1 acts_upstream_of_or_within ISO MGI:2181766 (MGI:1197816|PMID:9515963) RGD PMID:9515963 MGI:1197816 NCBI chr18:74,046,421...74,156,041
Ensembl chr18:74,046,904...74,156,028 		JBrowse link
G Scx scleraxis bHLH transcription factor involved_in ISO (MGI:4413438|PMID:18802027) RGD PMID:18802027 MGI:4413438 NCBI chr 7:108,176,608...108,178,626
Ensembl chr 7:108,176,608...108,178,626 		JBrowse link
G Sox9 SRY-box transcription factor 9 involved_in
acts_upstream_of_or_within		 ISS
ISO		 GO_REF:0000024
MGI:2176070|MGI:2385468 (MGI:3709829|PMID:17350610)		 UniProt
RGD		 PMID:17350610 GO_REF:0000024 MGI:3709829 NCBI chr10:97,806,485...97,811,994
Ensembl chr10:97,806,485...97,811,994 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 involved_in ISO (MGI:67103|PMID:8009224) RGD PMID:8009224 MGI:67103 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847 		JBrowse link
G Tgfb2 transforming growth factor, beta 2 involved_in
acts_upstream_of_or_within		 ISO (MGI:3609313|PMID:11390347)
MGI:1888389 (MGI:5140242|PMID:21780244)		 RGD PMID:11390347 PMID:21780244 MGI:3609313 MGI:5140242 NCBI chr13:98,160,075...98,261,771
Ensembl chr13:98,160,087...98,261,405 		JBrowse link
aortic valve morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp4 bone morphogenetic protein 4 involved_in IEA
ISO		 GO_REF:0000107
(MGI:3039210|PMID:15070745), (MGI:3814273|PMID:18924235)		 Ensembl
RGD		 PMID:15070745 PMID:18924235 GO_REF:0000107 MGI:3039210 MGI:3814273 NCBI chr15:19,618,538...19,633,494
Ensembl chr15:19,618,542...19,623,306 		JBrowse link
G Efna1 ephrin A1 involved_in ISO (MGI:4847981|PMID:20960543) RGD PMID:20960543 MGI:4847981 NCBI chr 2:174,681,676...174,690,306
Ensembl chr 2:174,681,682...174,690,866 		JBrowse link
G Emilin1 elastin microfibril interfacer 1 involved_in ISO (MGI:5605894|PMID:25056700) RGD PMID:25056700 MGI:5605894 NCBI chr 6:25,455,974...25,463,736
Ensembl chr 6:25,445,298...25,463,698 		JBrowse link
G Gata3 GATA binding protein 3 involved_in ISS
ISO		 GO_REF:0000024
(MGI:3832106|PMID:18955134)		 UniProt
RGD		 PMID:18955134 GO_REF:0000024 MGI:3832106 NCBI chr17:68,643,760...68,666,000
Ensembl chr17:68,643,873...68,665,391 		JBrowse link
G Gata4 GATA binding protein 4 involved_in ISO (PMID:29325903) RGD PMID:29325903 NCBI chr15:37,459,601...37,531,291
Ensembl chr15:37,459,601...37,505,636 		JBrowse link
G Gata5 GATA binding protein 5 involved_in ISO (PMID:22641149), (PMID:24638895)
(MGI:5286818|PMID:21633169)		 RGD PMID:21633169 PMID:22641149 PMID:24638895 MGI:5286818 NCBI chr 3:167,418,563...167,426,751
Ensembl chr 3:167,418,565...167,426,751 		JBrowse link
G Hey1 hes-related family bHLH transcription factor with YRPW motif 1 involved_in ISO (MGI:6158746|PMID:22110751) RGD PMID:22110751 MGI:6158746 NCBI chr 2:93,096,706...93,100,316
Ensembl chr 2:93,095,498...93,100,312 		JBrowse link
G Hey2 hes-related family bHLH transcription factor with YRPW motif 2 involved_in ISO (MGI:6158746|PMID:22110751) RGD PMID:22110751 MGI:6158746 NCBI chr 1:26,822,131...26,832,218
Ensembl chr 1:26,822,131...26,832,218 		JBrowse link
G Nfatc1 nuclear factor of activated T-cells 1 acts_upstream_of_or_within ISO MGI:2181762 (MGI:1197815|PMID:9515964) RGD PMID:9515964 MGI:1197815 NCBI chr18:74,046,421...74,156,041
Ensembl chr18:74,046,904...74,156,028 		JBrowse link
G Nos3 nitric oxide synthase 3 involved_in IEA
ISO		 GO_REF:0000107
UniProtKB:Q01705 (MGI:3609262|PMID:10821808), (MGI:6158784|PMID:27107132), (MGI:6158885|PMID:23583836)		 Ensembl
RGD		 PMID:10821808 PMID:23583836 PMID:27107132 GO_REF:0000107 MGI:3609262 MGI:6158784 MGI:6158885 NCBI chr 4:10,793,834...10,814,170
Ensembl chr 4:10,793,834...10,814,166 		JBrowse link
G Notch1 notch receptor 1 involved_in ISO (PMID:16025100), (PMID:17662764), (PMID:18593716)
UniProtKB:P70313 (MGI:6158728|PMID:26491108), (MGI:6158784|PMID:27107132), (MGI:6158885|PMID:23583836)		 RGD PMID:16025100 PMID:17662764 PMID:18593716 PMID:23583836 PMID:26491108 More... MGI:6158728 MGI:6158784 MGI:6158885 NCBI chr 3:9,277,955...9,323,531
Ensembl chr 3:9,278,086...9,323,531 		JBrowse link
G Rb1 RB transcriptional corepressor 1 involved_in IEA
ISO		 GO_REF:0000107
(MGI:6112863|PMID:29304157)		 Ensembl
RGD		 PMID:29304157 GO_REF:0000107 MGI:6112863 NCBI chr15:48,371,295...48,502,473
Ensembl chr15:48,371,296...48,502,302 		JBrowse link
G Robo1 roundabout guidance receptor 1 involved_in ISO UniProtKB:Q7TPD3 (MGI:5913048|PMID:25691540) RGD PMID:25691540 MGI:5913048 NCBI chr11:10,580,863...11,621,672
Ensembl chr11:10,580,908...11,620,203 		JBrowse link
G Robo2 roundabout guidance receptor 2 involved_in ISO UniProtKB:O89026 (MGI:5913048|PMID:25691540) RGD PMID:25691540 MGI:5913048 NCBI chr11:12,528,949...14,096,726
Ensembl chr11:12,528,951...13,041,536 		JBrowse link
G Rock1 Rho-associated coiled-coil containing protein kinase 1 involved_in ISO UniProtKB:M3TYT0 (PMID:26634652) RGD PMID:26634652 NCBI chr18:1,114,532...1,236,345
Ensembl chr18:1,115,905...1,235,571 		JBrowse link
G Rock2 Rho-associated coiled-coil containing protein kinase 2 involved_in ISO UniProtKB:I3LFH3 (PMID:26634652) RGD PMID:26634652 NCBI chr 6:39,679,116...39,774,033
Ensembl chr 6:39,679,082...39,774,031 		JBrowse link
G Slit2 slit guidance ligand 2 involved_in ISO (MGI:5913048|PMID:25691540) RGD PMID:25691540 MGI:5913048 NCBI chr14:62,616,337...62,955,934
Ensembl chr14:62,617,067...62,955,948 		JBrowse link
G Slit3 slit guidance ligand 3 involved_in IEA
ISO		 GO_REF:0000107
(MGI:5913048|PMID:25691540)		 Ensembl
RGD		 PMID:25691540 GO_REF:0000107 MGI:5913048 NCBI chr10:19,571,798...20,156,634
Ensembl chr10:19,571,684...20,156,634 		JBrowse link
G Smad6 SMAD family member 6 involved_in ISO (PMID:22275001) RGD PMID:22275001 NCBI chr 8:64,450,114...64,519,673
Ensembl chr 8:64,450,114...64,519,763 		JBrowse link
G Sox9 SRY-box transcription factor 9 involved_in ISO (PMID:22110751) RGD PMID:22110751 NCBI chr10:97,806,485...97,811,994
Ensembl chr10:97,806,485...97,811,994 		JBrowse link
G Tbx20 T-box transcription factor 20 involved_in ISO (PMID:18275040), (PMID:18834961) RGD PMID:18275040 PMID:18834961 NCBI chr 8:23,200,104...23,258,218
Ensembl chr 8:23,204,507...23,258,175 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 involved_in ISO (PMID:26634652)
(MGI:5921830|PMID:26634652)		 RGD PMID:26634652 MGI:5921830 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847 		JBrowse link
G Tie1 tyrosine kinase with immunoglobulin-like and EGF-like domains 1 involved_in ISO (MGI:6370101|PMID:31319059) RGD PMID:31319059 MGI:6370101 NCBI chr 5:132,000,013...132,019,658
Ensembl chr 5:132,000,015...132,019,592 		JBrowse link
G Twist1 twist family bHLH transcription factor 1 involved_in ISO (PMID:20804746)
(MGI:4838344|PMID:20804746)		 RGD PMID:20804746 MGI:4838344 NCBI chr 6:50,674,910...50,676,904
Ensembl chr 6:50,674,678...50,677,653 		JBrowse link
atrioventricular valve formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gata4 GATA binding protein 4 involved_in ISO UniProtKB:P97471 (MGI:4946551|PMID:21330551) RGD PMID:21330551 MGI:4946551 NCBI chr15:37,459,601...37,531,291
Ensembl chr15:37,459,601...37,505,636 		JBrowse link
G Hey1 hes-related family bHLH transcription factor with YRPW motif 1 involved_in ISO (MGI:3703467|PMID:17259303) RGD PMID:17259303 MGI:3703467 NCBI chr 2:93,096,706...93,100,316
Ensembl chr 2:93,095,498...93,100,312 		JBrowse link
G Olfm1 olfactomedin 1 involved_in ISS GO_REF:0000024 AgBase GO_REF:0000024 NCBI chr 3:11,520,522...11,558,240
Ensembl chr 3:11,520,729...11,558,239 		JBrowse link
G Smad4 SMAD family member 4 involved_in IEA
ISO		 GO_REF:0000107
UniProtKB:Q08369 (MGI:4946551|PMID:21330551)		 Ensembl
RGD		 PMID:21330551 GO_REF:0000107 MGI:4946551 NCBI chr18:67,243,742...67,274,438
Ensembl chr18:67,243,742...67,274,438 		JBrowse link
atrioventricular valve morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acvr1 activin A receptor type 1 involved_in ISO (MGI:3610266|PMID:16140292) RGD PMID:16140292 MGI:3610266 NCBI chr 3:42,978,558...43,097,892
Ensembl chr 3:42,978,561...43,098,241 		JBrowse link
G Bmp2 bone morphogenetic protein 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:3583785 (MGI:3611958|PMID:16314491)		 Ensembl
RGD		 PMID:16314491 GO_REF:0000107 MGI:3611958 NCBI chr 3:120,812,660...120,822,579
Ensembl chr 3:120,812,882...120,821,397 		JBrowse link
G Bmpr2 bone morphogenetic protein receptor type 2 NOT|involved_in ISO (MGI:2429424|PMID:12441304) RGD PMID:12441304 MGI:2429424 NCBI chr 9:61,192,718...61,307,280
Ensembl chr 9:61,190,566...61,301,809 		JBrowse link
G Ccn1 cellular communication network factor 1 acts_upstream_of_or_within ISO MGI:2446577 (MGI:3761425|PMID:17023674) RGD PMID:17023674 MGI:3761425 NCBI chr 2:234,562,410...234,565,370
Ensembl chr 2:234,562,408...234,565,484 		JBrowse link
G Gata4 GATA binding protein 4 acts_upstream_of_or_within ISO MGI:102541 (MGI:3833786|PMID:19084512) RGD PMID:19084512 MGI:3833786 NCBI chr15:37,459,601...37,531,291
Ensembl chr15:37,459,601...37,505,636 		JBrowse link
G Hey1 hes-related family bHLH transcription factor with YRPW motif 1 involved_in ISO UniProtKB:Q9DBX7 (MGI:3783952|PMID:17303760) RGD PMID:17303760 MGI:3783952 NCBI chr 2:93,096,706...93,100,316
Ensembl chr 2:93,095,498...93,100,312 		JBrowse link
G Heyl hes-related family bHLH transcription factor with YRPW motif-like involved_in ISO UniProtKB:Q9WV93 (MGI:3783952|PMID:17303760) RGD PMID:17303760 MGI:3783952 NCBI chr 5:135,508,160...135,525,152
Ensembl chr 5:135,508,160...135,525,152 		JBrowse link
G Mdm2 MDM2 proto-oncogene acts_upstream_of_or_within ISO MGI:107934 (MGI:5440773|PMID:22821713) RGD PMID:22821713 MGI:5440773 NCBI chr 7:53,290,660...53,315,205
Ensembl chr 7:53,290,664...53,314,915 		JBrowse link
G Mdm4 MDM4 regulator of p53 acts_upstream_of_or_within ISO MGI:96952 (MGI:5440773|PMID:22821713) RGD PMID:22821713 MGI:5440773 NCBI chr13:44,432,596...44,516,165
Ensembl chr13:44,406,213...44,474,226 		JBrowse link
G Notch1 notch receptor 1 involved_in ISO (MGI:3027664|PMID:14701881), (MGI:5000164|PMID:21266778) RGD PMID:14701881 PMID:21266778 MGI:3027664 MGI:5000164 NCBI chr 3:9,277,955...9,323,531
Ensembl chr 3:9,278,086...9,323,531 		JBrowse link
G Slit3 slit guidance ligand 3 involved_in IEA
ISO		 GO_REF:0000107
(MGI:5913048|PMID:25691540)		 Ensembl
RGD		 PMID:25691540 GO_REF:0000107 MGI:5913048 NCBI chr10:19,571,798...20,156,634
Ensembl chr10:19,571,684...20,156,634 		JBrowse link
G Tbx5 T-box transcription factor 5 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:95664 (MGI:3833786|PMID:19084512)		 Ensembl
RGD		 PMID:19084512 GO_REF:0000107 MGI:3833786 NCBI chr12:36,686,344...36,739,253
Ensembl chr12:36,688,014...36,734,885 		JBrowse link
G Tgfb2 transforming growth factor, beta 2 involved_in ISO (MGI:894212|PMID:9217007) RGD PMID:9217007 MGI:894212 NCBI chr13:98,160,075...98,261,771
Ensembl chr13:98,160,087...98,261,405 		JBrowse link
G Tgfbr2 transforming growth factor, beta receptor 2 involved_in ISO (MGI:4821522|PMID:20652948) RGD PMID:20652948 MGI:4821522 NCBI chr 8:115,794,537...115,883,615
Ensembl chr 8:115,794,537...115,883,228 		JBrowse link
G Zfpm1 zinc finger protein, multitype 1 involved_in ISO (MGI:3583527|PMID:14614148) RGD PMID:14614148 MGI:3583527 NCBI chr19:50,334,352...50,391,029
Ensembl chr19:50,334,682...50,390,591 		JBrowse link
coronary sinus valve morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Notch1 notch receptor 1 involved_in ISO (MGI:6158728|PMID:26491108) RGD PMID:26491108 MGI:6158728 NCBI chr 3:9,277,955...9,323,531
Ensembl chr 3:9,278,086...9,323,531 		JBrowse link
endocardial cushion to mesenchymal transition involved in heart valve formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Efna1 ephrin A1 involved_in ISO (MGI:4847981|PMID:20960543) RGD PMID:20960543 MGI:4847981 NCBI chr 2:174,681,676...174,690,306
Ensembl chr 2:174,681,682...174,690,866 		JBrowse link
G Erg ETS transcription factor ERG acts_upstream_of_or_within ISO MGI:5443838 (MGI:5442628|PMID:22932696) RGD PMID:22932696 MGI:5442628 NCBI chr11:34,678,614...34,900,951
Ensembl chr11:34,678,618...34,845,871 		JBrowse link
G Hey1 hes-related family bHLH transcription factor with YRPW motif 1 acts_upstream_of_or_within ISO MGI:1341884 (MGI:3530185|PMID:15680351) RGD PMID:15680351 MGI:3530185 NCBI chr 2:93,096,706...93,100,316
Ensembl chr 2:93,095,498...93,100,312 		JBrowse link
G Hey2 hes-related family bHLH transcription factor with YRPW motif 2 acts_upstream_of_or_within ISO MGI:1341800 (MGI:3530185|PMID:15680351) RGD PMID:15680351 MGI:3530185 NCBI chr 1:26,822,131...26,832,218
Ensembl chr 1:26,822,131...26,832,218 		JBrowse link
heart valve formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Scx scleraxis bHLH transcription factor involved_in ISO (MGI:4413438|PMID:18802027) RGD PMID:18802027 MGI:4413438 NCBI chr 7:108,176,608...108,178,626
Ensembl chr 7:108,176,608...108,178,626 		JBrowse link
G Sox9 SRY-box transcription factor 9 acts_upstream_of_or_within ISO MGI:2385468|MGI:2450311 (MGI:3709829|PMID:17350610) RGD PMID:17350610 MGI:3709829 NCBI chr10:97,806,485...97,811,994
Ensembl chr10:97,806,485...97,811,994 		JBrowse link
mitral valve formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dchs1 dachsous cadherin-related 1 involved_in ISO (PMID:26258302) RGD PMID:26258302 NCBI chr 1:160,104,931...160,138,958
Ensembl chr 1:160,104,931...160,124,808 		JBrowse link
G Notch1 notch receptor 1 involved_in ISO (PMID:16025100) RGD PMID:16025100 NCBI chr 3:9,277,955...9,323,531
Ensembl chr 3:9,278,086...9,323,531 		JBrowse link
G Zfpm1 zinc finger protein, multitype 1 involved_in ISO (MGI:3583527|PMID:14614148) RGD PMID:14614148 MGI:3583527 NCBI chr19:50,334,352...50,391,029
Ensembl chr19:50,334,682...50,390,591 		JBrowse link
mitral valve morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acvr1 activin A receptor type 1 involved_in ISO (PMID:19506109) RGD PMID:19506109 NCBI chr 3:42,978,558...43,097,892
Ensembl chr 3:42,978,561...43,098,241 		JBrowse link
G Bmpr1a bone morphogenetic protein receptor type 1A involved_in ISO (MGI:3653945|PMID:16037571) RGD PMID:16037571 MGI:3653945 NCBI chr16:9,736,390...9,829,825
Ensembl chr16:9,736,630...9,780,616 		JBrowse link
G Bmpr2 bone morphogenetic protein receptor type 2 involved_in ISO (MGI:3851675|PMID:19409885) RGD PMID:19409885 MGI:3851675 NCBI chr 9:61,192,718...61,307,280
Ensembl chr 9:61,190,566...61,301,809 		JBrowse link
G Dchs1 dachsous cadherin-related 1 acts_upstream_of_or_within
involved_in		 ISO MGI:4867020 (MGI:5694502|PMID:26258302) RGD PMID:26258302 MGI:5694502 NCBI chr 1:160,104,931...160,138,958
Ensembl chr 1:160,104,931...160,124,808 		JBrowse link
G Efna1 ephrin A1 involved_in ISO (MGI:4847981|PMID:20960543) RGD PMID:20960543 MGI:4847981 NCBI chr 2:174,681,676...174,690,306
Ensembl chr 2:174,681,682...174,690,866 		JBrowse link
G Smad6 SMAD family member 6 involved_in ISO (MGI:1352979|PMID:10655064) RGD PMID:10655064 MGI:1352979 NCBI chr 8:64,450,114...64,519,673
Ensembl chr 8:64,450,114...64,519,763 		JBrowse link
G Sox4 SRY-box transcription factor 4 involved_in ISO (MGI:3603061|PMID:16109771) RGD PMID:16109771 MGI:3603061 NCBI chr17:35,667,809...35,672,515
Ensembl chr17:35,667,537...35,673,665 		JBrowse link
G Twist1 twist family bHLH transcription factor 1 involved_in ISO (MGI:4838344|PMID:20804746) RGD PMID:20804746 MGI:4838344 NCBI chr 6:50,674,910...50,676,904
Ensembl chr 6:50,674,678...50,677,653 		JBrowse link
negative regulation of cell proliferation involved in heart valve morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmpr2 bone morphogenetic protein receptor type 2 involved_in ISO (MGI:3851675|PMID:19409885) RGD PMID:19409885 MGI:3851675 NCBI chr 9:61,192,718...61,307,280
Ensembl chr 9:61,190,566...61,301,809 		JBrowse link
G Notch1 notch receptor 1 involved_in ISO (MGI:6158728|PMID:26491108) RGD PMID:26491108 MGI:6158728 NCBI chr 3:9,277,955...9,323,531
Ensembl chr 3:9,278,086...9,323,531 		JBrowse link
positive regulation of cell proliferation involved in heart valve morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Smad4 SMAD family member 4 involved_in IEA
ISO		 GO_REF:0000107
(MGI:4946551|PMID:21330551)		 Ensembl
RGD		 PMID:21330551 GO_REF:0000107 MGI:4946551 NCBI chr18:67,243,742...67,274,438
Ensembl chr18:67,243,742...67,274,438 		JBrowse link
positive regulation of endocardial cushion to mesenchymal transition involved in heart valve formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Twist1 twist family bHLH transcription factor 1 involved_in ISO (MGI:4838344|PMID:20804746) RGD PMID:20804746 MGI:4838344 NCBI chr 6:50,674,910...50,676,904
Ensembl chr 6:50,674,678...50,677,653 		JBrowse link
pulmonary valve formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gja5 gap junction protein, alpha 5 involved_in ISO (PMID:22199024) RGD PMID:22199024 NCBI chr 2:184,602,407...184,621,952
Ensembl chr 2:184,564,475...184,621,952 		JBrowse link
G Tbx20 T-box transcription factor 20 involved_in ISO (MGI:3604925|PMID:15843409) RGD PMID:15843409 MGI:3604925 NCBI chr 8:23,200,104...23,258,218
Ensembl chr 8:23,204,507...23,258,175 		JBrowse link
pulmonary valve morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp4 bone morphogenetic protein 4 involved_in IEA
ISO		 GO_REF:0000107
(MGI:3039210|PMID:15070745), (MGI:3814273|PMID:18924235)		 Ensembl
RGD		 PMID:15070745 PMID:18924235 GO_REF:0000107 MGI:3039210 MGI:3814273 NCBI chr15:19,618,538...19,633,494
Ensembl chr15:19,618,542...19,623,306 		JBrowse link
G Hey1 hes-related family bHLH transcription factor with YRPW motif 1 involved_in ISO UniProtKB:Q9DBX7 (MGI:3783952|PMID:17303760) RGD PMID:17303760 MGI:3783952 NCBI chr 2:93,096,706...93,100,316
Ensembl chr 2:93,095,498...93,100,312 		JBrowse link
G Hey2 hes-related family bHLH transcription factor with YRPW motif 2 involved_in ISO (MGI:2386835|PMID:12372254) RGD PMID:12372254 MGI:2386835 NCBI chr 1:26,822,131...26,832,218
Ensembl chr 1:26,822,131...26,832,218 		JBrowse link
G Heyl hes-related family bHLH transcription factor with YRPW motif-like involved_in ISO UniProtKB:Q9WV93 (MGI:3783952|PMID:17303760) RGD PMID:17303760 MGI:3783952 NCBI chr 5:135,508,160...135,525,152
Ensembl chr 5:135,508,160...135,525,152 		JBrowse link
G Jag1 jagged canonical Notch ligand 1 involved_in IEA
ISO		 GO_REF:0000107
(PMID:20437614), (PMID:9207787)		 Ensembl
RGD		 PMID:9207787 PMID:20437614 GO_REF:0000107 NCBI chr 3:124,406,794...124,442,220
Ensembl chr 3:124,406,794...124,442,209 		JBrowse link
G Nfatc1 nuclear factor of activated T-cells 1 acts_upstream_of_or_within ISO MGI:2181762 (MGI:1197815|PMID:9515964) RGD PMID:9515964 MGI:1197815 NCBI chr18:74,046,421...74,156,041
Ensembl chr18:74,046,904...74,156,028 		JBrowse link
G Nos3 nitric oxide synthase 3 involved_in IEA
ISO		 GO_REF:0000107
UniProtKB:Q01705 (MGI:6158784|PMID:27107132)		 Ensembl
RGD		 PMID:27107132 GO_REF:0000107 MGI:6158784 NCBI chr 4:10,793,834...10,814,170
Ensembl chr 4:10,793,834...10,814,166 		JBrowse link
G Notch1 notch receptor 1 involved_in ISO (PMID:16025100)
UniProtKB:P70313 (MGI:6158728|PMID:26491108), (MGI:6158784|PMID:27107132)		 RGD PMID:16025100 PMID:26491108 PMID:27107132 MGI:6158728 MGI:6158784 NCBI chr 3:9,277,955...9,323,531
Ensembl chr 3:9,278,086...9,323,531 		JBrowse link
G Notch2 notch receptor 2 involved_in ISO
IEA		 (PMID:16773578)
GO_REF:0000107		 RGD
Ensembl		 PMID:16773578 GO_REF:0000107 NCBI chr 2:185,610,594...185,744,088
Ensembl chr 2:185,610,589...185,744,088 		JBrowse link
G Robo1 roundabout guidance receptor 1 involved_in ISO UniProtKB:Q7TPD3 (MGI:5913048|PMID:25691540) RGD PMID:25691540 MGI:5913048 NCBI chr11:10,580,863...11,621,672
Ensembl chr11:10,580,908...11,620,203 		JBrowse link
G Robo2 roundabout guidance receptor 2 involved_in ISO UniProtKB:O89026 (MGI:5913048|PMID:25691540) RGD PMID:25691540 MGI:5913048 NCBI chr11:12,528,949...14,096,726
Ensembl chr11:12,528,951...13,041,536 		JBrowse link
G Slit2 slit guidance ligand 2 involved_in ISO (MGI:5913048|PMID:25691540) RGD PMID:25691540 MGI:5913048 NCBI chr14:62,616,337...62,955,934
Ensembl chr14:62,617,067...62,955,948 		JBrowse link
G Smad6 SMAD family member 6 involved_in ISO (MGI:1352979|PMID:10655064) RGD PMID:10655064 MGI:1352979 NCBI chr 8:64,450,114...64,519,673
Ensembl chr 8:64,450,114...64,519,763 		JBrowse link
G Stra6 signaling receptor and transporter of retinol STRA6 involved_in ISO (PMID:17273977) RGD PMID:17273977 NCBI chr 8:58,549,743...58,568,861
Ensembl chr 8:58,549,736...58,568,860 		JBrowse link
G Tgfb2 transforming growth factor, beta 2 involved_in ISO (MGI:894212|PMID:9217007) RGD PMID:9217007 MGI:894212 NCBI chr13:98,160,075...98,261,771
Ensembl chr13:98,160,087...98,261,405 		JBrowse link
sinoatrial valve morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mef2c myocyte enhancer factor 2C involved_in ISS
ISO		 GO_REF:0000024
(MGI:3830899|PMID:16680724)		 UniProt
RGD		 PMID:16680724 GO_REF:0000024 MGI:3830899 NCBI chr 2:13,973,299...14,136,065
Ensembl chr 2:13,993,438...14,132,880 		JBrowse link
tricuspid valve formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hey2 hes-related family bHLH transcription factor with YRPW motif 2 acts_upstream_of_or_within ISO MGI:3574394 (MGI:3574376|PMID:15297376) RGD PMID:15297376 MGI:3574376 NCBI chr 1:26,822,131...26,832,218
Ensembl chr 1:26,822,131...26,832,218 		JBrowse link
G Zfpm1 zinc finger protein, multitype 1 involved_in ISO (MGI:3583527|PMID:14614148) RGD PMID:14614148 MGI:3583527 NCBI chr19:50,334,352...50,391,029
Ensembl chr19:50,334,682...50,390,591 		JBrowse link
tricuspid valve morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmpr1a bone morphogenetic protein receptor type 1A involved_in ISO (MGI:3653945|PMID:16037571) RGD PMID:16037571 MGI:3653945 NCBI chr16:9,736,390...9,829,825
Ensembl chr16:9,736,630...9,780,616 		JBrowse link
G Bmpr2 bone morphogenetic protein receptor type 2 involved_in ISO (MGI:3851675|PMID:19409885) RGD PMID:19409885 MGI:3851675 NCBI chr 9:61,192,718...61,307,280
Ensembl chr 9:61,190,566...61,301,809 		JBrowse link
G Hey2 hes-related family bHLH transcription factor with YRPW motif 2 involved_in ISO (MGI:2386835|PMID:12372254) RGD PMID:12372254 MGI:2386835 NCBI chr 1:26,822,131...26,832,218
Ensembl chr 1:26,822,131...26,832,218 		JBrowse link
G Tgfbr2 transforming growth factor, beta receptor 2 involved_in ISO (MGI:4821522|PMID:20652948) RGD PMID:20652948 MGI:4821522 NCBI chr 8:115,794,537...115,883,615
Ensembl chr 8:115,794,537...115,883,228 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20094
    developmental process 7006
      anatomical structure morphogenesis 2999
        heart valve morphogenesis 50
          aortic valve morphogenesis + 24
          apoptotic process involved in heart valve morphogenesis 0
          atrioventricular valve morphogenesis + 24
          cell proliferation involved in heart valve morphogenesis + 3
          coronary sinus valve morphogenesis + 1
          heart valve formation + 15
          pulmonary valve morphogenesis + 17
          sinoatrial valve morphogenesis + 1
          ventriculo bulbo valve morphogenesis + 0
Path 2
Term Annotations click to browse term
  biological_process 20094
    developmental process 7006
      anatomical structure development 6444
        multicellular organism development 5224
          system development 4484
            circulatory system development 1328
              heart development 719
                heart valve development 61
                  heart valve morphogenesis 50
                    aortic valve morphogenesis + 24
                    apoptotic process involved in heart valve morphogenesis 0
                    atrioventricular valve morphogenesis + 24
                    cell proliferation involved in heart valve morphogenesis + 3
                    coronary sinus valve morphogenesis + 1
                    heart valve formation + 15
                    pulmonary valve morphogenesis + 17
                    sinoatrial valve morphogenesis + 1
                    ventriculo bulbo valve morphogenesis + 0
paths to the root