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ONTOLOGY REPORT - ANNOTATIONS


Term:heart valve morphogenesis
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Accession:GO:0003179 term browser browse the term
Definition:The process in which the structure of a heart valve is generated and organized.
Synonyms:narrow_synonym: heart valve remodeling;   heart valve remodelling



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heart valve morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADAMTS9 ADAM metallopeptidase with thrombospondin type 1 motif 9 involved_in ISO (MGI:4452308|PMID:20096780) BHF-UCL PMID:20096780 MGI:4452308 NCBI chr20:26,589,529...26,749,422
Ensembl chr20:26,588,654...26,748,604
JBrowse link
G B9D2 B9 domain containing 2 involved_in ISO (MGI:67103|PMID:8009224) BHF-UCL PMID:8009224 MGI:67103 NCBI chr 1:112,621,832...112,627,726
Ensembl chr 1:112,621,633...112,643,885
JBrowse link
G FGFRL1 fibroblast growth factor receptor like 1 acts_upstream_of_or_within ISO (MGI:3848851|PMID:19383940) MGI PMID:19383940 MGI:3848851 NCBI chr 3:91,499,088...91,508,982 JBrowse link
G MTOR mechanistic target of rapamycin kinase acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:5632243|PMID:25139234) MGI
Ensembl
PMID:25139234 GO_REF:0000107 MGI:5632243 NCBI chr 2:84,818,893...84,939,283
Ensembl chr 2:84,787,708...84,939,114
JBrowse link
G NFATC1 nuclear factor of activated T cells 1 acts_upstream_of_or_within ISO (MGI:1197816|PMID:9515963) MGI PMID:9515963 MGI:1197816 NCBI chr 1:1,027,021...1,121,362
Ensembl chr 1:1,028,695...1,121,588
JBrowse link
G SCX scleraxis bHLH transcription factor involved_in ISS UniProt GO_REF:0000024 NCBI chr13:37,701,781...37,704,949
Ensembl chr13:37,703,232...37,704,657
JBrowse link
G SOX9 SRY-box transcription factor 9 involved_in
acts_upstream_of_or_within
ISS
ISO
(MGI:3709829|PMID:17350610) UniProt
MGI
UniProt
PMID:17350610 GO_REF:0000024 MGI:3709829 NCBI chr 9:8,275,049...8,278,172
Ensembl chr 9:8,275,049...8,278,172
JBrowse link
G TGFB1 transforming growth factor beta 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:112,629,476...112,643,885
Ensembl chr 1:112,621,633...112,643,885
JBrowse link
G TGFB2 transforming growth factor beta 2 acts_upstream_of_or_within
involved_in
ISO (MGI:5140242|PMID:21780244)
(MGI:3609313|PMID:11390347)
MGI
BHF-UCL
PMID:11390347 PMID:21780244 MGI:3609313 MGI:5140242 NCBI chr38:13,430,832...13,511,655
Ensembl chr38:13,429,148...13,510,242
JBrowse link
aortic valve morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G B9D2 B9 domain containing 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:112,621,832...112,627,726
Ensembl chr 1:112,621,633...112,643,885
JBrowse link
G BMP4 bone morphogenetic protein 4 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 8:29,997,563...30,254,307
Ensembl chr 8:29,997,569...30,004,557
JBrowse link
G EFNA1 ephrin A1 involved_in ISO (MGI:4847981|PMID:20960543) BHF-UCL PMID:20960543 MGI:4847981 NCBI chr 7:42,373,197...42,381,161
Ensembl chr 7:42,373,639...42,378,946
JBrowse link
G EMILIN1 elastin microfibril interfacer 1 involved_in ISO (MGI:5605894|PMID:25056700) BHF-UCL PMID:25056700 MGI:5605894 NCBI chr17:21,071,502...21,078,888
Ensembl chr17:21,071,580...21,078,889
JBrowse link
G GATA3 GATA binding protein 3 involved_in ISS UniProt GO_REF:0000024 NCBI chr 2:28,068,143...28,098,445
Ensembl chr 2:28,069,051...28,087,760
JBrowse link
G GATA4 GATA binding protein 4 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr25:26,126,172...26,211,474
Ensembl chr25:26,127,853...26,182,989
JBrowse link
G GATA5 GATA binding protein 5 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr24:46,417,404...46,427,617
Ensembl chr24:46,417,391...46,429,858
JBrowse link
G HEY1 hes related family bHLH transcription factor with YRPW motif 1 involved_in ISO (MGI:6158746|PMID:22110751) BHF-UCL PMID:22110751 MGI:6158746 NCBI chr29:27,185,191...27,188,121
Ensembl chr29:27,185,191...27,188,121
JBrowse link
G HEY2 hes related family bHLH transcription factor with YRPW motif 2 involved_in ISO (MGI:6158746|PMID:22110751) BHF-UCL PMID:22110751 MGI:6158746 NCBI chr 1:64,630,656...64,646,546 JBrowse link
G NFATC1 nuclear factor of activated T cells 1 acts_upstream_of_or_within ISO (MGI:1197815|PMID:9515964) MGI PMID:9515964 MGI:1197815 NCBI chr 1:1,027,021...1,121,362
Ensembl chr 1:1,028,695...1,121,588
JBrowse link
G NOS3 nitric oxide synthase 3 involved_in ISO (MGI:6158784|PMID:27107132)
(MGI:3609262|PMID:10821808), (MGI:6158885|PMID:23583836)
BHF-UCL PMID:10821808 PMID:23583836 PMID:27107132 MGI:3609262 MGI:6158784 MGI:6158885 NCBI chr16:15,054,196...15,072,454
Ensembl chr16:15,011,344...15,072,277
JBrowse link
G NOTCH1 notch receptor 1 involved_in ISO (PMID:16025100), (PMID:17662764), (PMID:18593716)
(MGI:6158784|PMID:27107132), (MGI:6158885|PMID:23583836)
(MGI:6158728|PMID:26491108)
BHF-UCL PMID:16025100 PMID:17662764 PMID:18593716 PMID:23583836 PMID:26491108 More... MGI:6158728 MGI:6158784 MGI:6158885 NCBI chr 9:48,975,972...49,018,985
Ensembl chr 9:48,974,757...49,017,277
JBrowse link
G RB1 RB transcriptional corepressor 1 involved_in ISO (MGI:6112863|PMID:29304157) BHF-UCL PMID:29304157 MGI:6112863 NCBI chr22:3,061,621...3,204,625
Ensembl chr22:3,063,239...3,257,726
JBrowse link
G ROBO1 roundabout guidance receptor 1 involved_in ISO (MGI:5913048|PMID:25691540) BHF-UCL PMID:25691540 MGI:5913048 NCBI chr31:8,082,363...8,594,623
Ensembl chr31:7,626,126...8,593,728
JBrowse link
G ROBO2 roundabout guidance receptor 2 involved_in ISO (MGI:5913048|PMID:25691540) BHF-UCL PMID:25691540 MGI:5913048 NCBI chr31:9,415,390...11,047,710
Ensembl chr31:9,419,026...11,022,392
JBrowse link
G ROCK1 Rho associated coiled-coil containing protein kinase 1 involved_in ISO (PMID:26634652) BHF-UCL PMID:26634652 NCBI chr 7:66,862,614...67,001,538
Ensembl chr 7:66,862,608...67,142,853
JBrowse link
G ROCK2 Rho associated coiled-coil containing protein kinase 2 involved_in ISO (PMID:26634652) BHF-UCL PMID:26634652 NCBI chr17:7,931,786...8,012,484
Ensembl chr17:7,934,739...8,178,707
JBrowse link
G SLIT2 slit guidance ligand 2 involved_in ISO (MGI:5913048|PMID:25691540) BHF-UCL PMID:25691540 MGI:5913048 NCBI chr 3:88,964,707...89,311,817
Ensembl chr 3:88,966,232...89,312,955
JBrowse link
G SLIT3 slit guidance ligand 3 involved_in ISO (MGI:5913048|PMID:25691540) BHF-UCL PMID:25691540 MGI:5913048 NCBI chr 4:42,506,680...43,099,053
Ensembl chr 4:42,508,426...43,094,714
JBrowse link
G SMAD6 SMAD family member 6 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr30:30,938,908...31,014,259
Ensembl chr30:30,937,849...31,014,583
JBrowse link
G SOX9 SRY-box transcription factor 9 involved_in ISO (PMID:22110751) BHF-UCL PMID:22110751 NCBI chr 9:8,275,049...8,278,172
Ensembl chr 9:8,275,049...8,278,172
JBrowse link
G TBX20 T-box transcription factor 20 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr14:46,891,706...46,946,899
Ensembl chr14:46,896,228...46,947,507
JBrowse link
G TGFB1 transforming growth factor beta 1 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 1:112,629,476...112,643,885
Ensembl chr 1:112,621,633...112,643,885
JBrowse link
G TIE1 tyrosine kinase with immunoglobulin like and EGF like domains 1 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr15:16,838,267...16,857,004
Ensembl chr15:16,838,582...16,856,946
JBrowse link
G TWIST1 twist family bHLH transcription factor 1 involved_in ISO (PMID:20804746)
(MGI:4838344|PMID:20804746)
BHF-UCL PMID:20804746 MGI:4838344
atrioventricular valve formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GATA4 GATA binding protein 4 involved_in ISO (MGI:4946551|PMID:21330551) BHF-UCL PMID:21330551 MGI:4946551 NCBI chr25:26,126,172...26,211,474
Ensembl chr25:26,127,853...26,182,989
JBrowse link
G HEY1 hes related family bHLH transcription factor with YRPW motif 1 involved_in ISO (MGI:3703467|PMID:17259303) BHF-UCL PMID:17259303 MGI:3703467 NCBI chr29:27,185,191...27,188,121
Ensembl chr29:27,185,191...27,188,121
JBrowse link
G SMAD4 SMAD family member 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:23,875,989...23,930,027
Ensembl chr 1:23,882,139...23,969,405
JBrowse link
atrioventricular valve morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACVR1 activin A receptor type 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr36:3,743,257...3,818,659
Ensembl chr36:3,744,163...3,818,652
JBrowse link
G BMP2 bone morphogenetic protein 2 acts_upstream_of_or_within ISO (MGI:3611958|PMID:16314491) MGI PMID:16314491 MGI:3611958 NCBI chr24:15,199,667...15,211,509
Ensembl chr24:15,200,291...15,212,217
JBrowse link
G BMPR2 bone morphogenetic protein receptor type 2 NOT|involved_in ISO (MGI:2429424|PMID:12441304) BHF-UCL PMID:12441304 MGI:2429424 NCBI chr37:11,342,292...11,540,199
Ensembl chr37:11,342,384...11,533,024
JBrowse link
G CCN1 cellular communication network factor 1 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:3761425|PMID:17023674) Ensembl
MGI
PMID:17023674 GO_REF:0000107 MGI:3761425 NCBI chr 6:62,443,285...62,446,246
Ensembl chr 6:62,443,675...62,445,994
JBrowse link
G GATA4 GATA binding protein 4 acts_upstream_of_or_within ISO (MGI:3833786|PMID:19084512) MGI PMID:19084512 MGI:3833786 NCBI chr25:26,126,172...26,211,474
Ensembl chr25:26,127,853...26,182,989
JBrowse link
G HEY1 hes related family bHLH transcription factor with YRPW motif 1 involved_in ISO (MGI:3783952|PMID:17303760) BHF-UCL PMID:17303760 MGI:3783952 NCBI chr29:27,185,191...27,188,121
Ensembl chr29:27,185,191...27,188,121
JBrowse link
G HEYL hes related family bHLH transcription factor with YRPW motif like involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr15:3,242,738...3,257,275
Ensembl chr15:3,235,611...3,303,445
JBrowse link
G MDM2 MDM2 proto-oncogene acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:5440773|PMID:22821713) MGI
Ensembl
PMID:22821713 GO_REF:0000107 MGI:5440773 NCBI chr10:10,936,288...10,963,118
Ensembl chr10:10,893,719...10,962,596
JBrowse link
G MDM4 MDM4 regulator of p53 acts_upstream_of_or_within ISO (MGI:5440773|PMID:22821713) MGI PMID:22821713 MGI:5440773 NCBI chr38:1,055,978...1,122,348
Ensembl chr38:1,056,109...1,107,166
JBrowse link
G NOTCH1 notch receptor 1 involved_in ISO (MGI:3027664|PMID:14701881), (MGI:5000164|PMID:21266778) BHF-UCL PMID:14701881 PMID:21266778 MGI:3027664 MGI:5000164 NCBI chr 9:48,975,972...49,018,985
Ensembl chr 9:48,974,757...49,017,277
JBrowse link
G SLIT3 slit guidance ligand 3 involved_in ISO (MGI:5913048|PMID:25691540) BHF-UCL PMID:25691540 MGI:5913048 NCBI chr 4:42,506,680...43,099,053
Ensembl chr 4:42,508,426...43,094,714
JBrowse link
G TBX5 T-box transcription factor 5 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:3833786|PMID:19084512) Ensembl
Ensembl
MGI
PMID:19084512 GO_REF:0000107 MGI:3833786 NCBI chr26:11,462,541...11,549,699
Ensembl chr26:11,463,653...11,506,446
JBrowse link
G TGFB2 transforming growth factor beta 2 involved_in ISO (MGI:894212|PMID:9217007) BHF-UCL PMID:9217007 MGI:894212 NCBI chr38:13,430,832...13,511,655
Ensembl chr38:13,429,148...13,510,242
JBrowse link
G TGFBR2 transforming growth factor beta receptor 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr23:13,886,869...13,946,480
Ensembl chr23:13,889,000...13,977,636
JBrowse link
G ZFPM1 zinc finger protein, FOG family member 1 involved_in ISO (MGI:3583527|PMID:14614148) BHF-UCL PMID:14614148 MGI:3583527 NCBI chr 5:64,812,353...64,863,278 JBrowse link
coronary sinus valve morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NOTCH1 notch receptor 1 involved_in ISO (MGI:6158728|PMID:26491108) BHF-UCL PMID:26491108 MGI:6158728 NCBI chr 9:48,975,972...49,018,985
Ensembl chr 9:48,974,757...49,017,277
JBrowse link
endocardial cushion to mesenchymal transition involved in heart valve formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G EFNA1 ephrin A1 involved_in ISO (MGI:4847981|PMID:20960543) BHF-UCL PMID:20960543 MGI:4847981 NCBI chr 7:42,373,197...42,381,161
Ensembl chr 7:42,373,639...42,378,946
JBrowse link
G ERG ETS transcription factor ERG acts_upstream_of_or_within ISO (MGI:5442628|PMID:22932696) MGI PMID:22932696 MGI:5442628 NCBI chr31:33,456,902...33,562,704
Ensembl chr31:33,497,209...33,515,272
JBrowse link
G HEY1 hes related family bHLH transcription factor with YRPW motif 1 acts_upstream_of_or_within ISO (MGI:3530185|PMID:15680351) MGI PMID:15680351 MGI:3530185 NCBI chr29:27,185,191...27,188,121
Ensembl chr29:27,185,191...27,188,121
JBrowse link
G HEY2 hes related family bHLH transcription factor with YRPW motif 2 acts_upstream_of_or_within ISO (MGI:3530185|PMID:15680351) MGI PMID:15680351 MGI:3530185 NCBI chr 1:64,630,656...64,646,546 JBrowse link
heart valve formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SCX scleraxis bHLH transcription factor involved_in ISS UniProt GO_REF:0000024 NCBI chr13:37,701,781...37,704,949
Ensembl chr13:37,703,232...37,704,657
JBrowse link
G SOX9 SRY-box transcription factor 9 acts_upstream_of_or_within ISO (MGI:3709829|PMID:17350610) MGI PMID:17350610 MGI:3709829 NCBI chr 9:8,275,049...8,278,172
Ensembl chr 9:8,275,049...8,278,172
JBrowse link
mitral valve formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DCHS1 dachsous cadherin-related 1 involved_in ISO (PMID:26258302) UniProt PMID:26258302 NCBI chr21:29,927,713...29,955,742
Ensembl chr21:29,928,176...29,948,713
JBrowse link
G NOTCH1 notch receptor 1 involved_in ISO (PMID:16025100) BHF-UCL PMID:16025100 NCBI chr 9:48,975,972...49,018,985
Ensembl chr 9:48,974,757...49,017,277
JBrowse link
G ZFPM1 zinc finger protein, FOG family member 1 involved_in ISO (MGI:3583527|PMID:14614148) BHF-UCL PMID:14614148 MGI:3583527 NCBI chr 5:64,812,353...64,863,278 JBrowse link
mitral valve morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACVR1 activin A receptor type 1 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr36:3,743,257...3,818,659
Ensembl chr36:3,744,163...3,818,652
JBrowse link
G BMPR1A bone morphogenetic protein receptor type 1A involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 4:34,499,898...34,582,481
Ensembl chr 4:34,517,492...34,578,923
JBrowse link
G BMPR2 bone morphogenetic protein receptor type 2 involved_in ISO (MGI:3851675|PMID:19409885) BHF-UCL PMID:19409885 MGI:3851675 NCBI chr37:11,342,292...11,540,199
Ensembl chr37:11,342,384...11,533,024
JBrowse link
G DCHS1 dachsous cadherin-related 1 involved_in
acts_upstream_of_or_within
ISO (MGI:5694502|PMID:26258302) MGI PMID:26258302 MGI:5694502 NCBI chr21:29,927,713...29,955,742
Ensembl chr21:29,928,176...29,948,713
JBrowse link
G EFNA1 ephrin A1 involved_in ISO (MGI:4847981|PMID:20960543) BHF-UCL PMID:20960543 MGI:4847981 NCBI chr 7:42,373,197...42,381,161
Ensembl chr 7:42,373,639...42,378,946
JBrowse link
G SMAD6 SMAD family member 6 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr30:30,938,908...31,014,259
Ensembl chr30:30,937,849...31,014,583
JBrowse link
G SOX4 SRY-box transcription factor 4 involved_in ISO (MGI:3603061|PMID:16109771) BHF-UCL PMID:16109771 MGI:3603061 NCBI chr35:20,098,783...20,101,357
Ensembl chr35:20,099,773...20,101,154
JBrowse link
G TWIST1 twist family bHLH transcription factor 1 involved_in ISO (MGI:4838344|PMID:20804746) BHF-UCL PMID:20804746 MGI:4838344
negative regulation of cell proliferation involved in heart valve morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BMPR2 bone morphogenetic protein receptor type 2 involved_in ISO (MGI:3851675|PMID:19409885) BHF-UCL PMID:19409885 MGI:3851675 NCBI chr37:11,342,292...11,540,199
Ensembl chr37:11,342,384...11,533,024
JBrowse link
G NOTCH1 notch receptor 1 involved_in ISO (MGI:6158728|PMID:26491108) BHF-UCL PMID:26491108 MGI:6158728 NCBI chr 9:48,975,972...49,018,985
Ensembl chr 9:48,974,757...49,017,277
JBrowse link
positive regulation of cell proliferation involved in heart valve morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SMAD4 SMAD family member 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:23,875,989...23,930,027
Ensembl chr 1:23,882,139...23,969,405
JBrowse link
positive regulation of endocardial cushion to mesenchymal transition involved in heart valve formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TWIST1 twist family bHLH transcription factor 1 involved_in ISO (MGI:4838344|PMID:20804746) BHF-UCL PMID:20804746 MGI:4838344
pulmonary valve formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GJA5 gap junction protein alpha 5 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr17:58,289,327...58,305,315
Ensembl chr17:58,289,327...58,305,315
JBrowse link
G TBX20 T-box transcription factor 20 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr14:46,891,706...46,946,899
Ensembl chr14:46,896,228...46,947,507
JBrowse link
pulmonary valve morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BMP4 bone morphogenetic protein 4 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 8:29,997,563...30,254,307
Ensembl chr 8:29,997,569...30,004,557
JBrowse link
G HEY1 hes related family bHLH transcription factor with YRPW motif 1 involved_in ISO (MGI:3783952|PMID:17303760) BHF-UCL PMID:17303760 MGI:3783952 NCBI chr29:27,185,191...27,188,121
Ensembl chr29:27,185,191...27,188,121
JBrowse link
G HEY2 hes related family bHLH transcription factor with YRPW motif 2 involved_in ISO (MGI:2386835|PMID:12372254) BHF-UCL PMID:12372254 MGI:2386835 NCBI chr 1:64,630,656...64,646,546 JBrowse link
G HEYL hes related family bHLH transcription factor with YRPW motif like involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr15:3,242,738...3,257,275
Ensembl chr15:3,235,611...3,303,445
JBrowse link
G JAG1 jagged canonical Notch ligand 1 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr24:11,656,926...11,693,146
Ensembl chr24:11,657,416...11,692,199
JBrowse link
G NFATC1 nuclear factor of activated T cells 1 acts_upstream_of_or_within ISO (MGI:1197815|PMID:9515964) MGI PMID:9515964 MGI:1197815 NCBI chr 1:1,027,021...1,121,362
Ensembl chr 1:1,028,695...1,121,588
JBrowse link
G NOS3 nitric oxide synthase 3 involved_in ISO (MGI:6158784|PMID:27107132) BHF-UCL PMID:27107132 MGI:6158784 NCBI chr16:15,054,196...15,072,454
Ensembl chr16:15,011,344...15,072,277
JBrowse link
G NOTCH1 notch receptor 1 involved_in ISO (PMID:16025100)
(MGI:6158784|PMID:27107132)
(MGI:6158728|PMID:26491108)
BHF-UCL PMID:16025100 PMID:26491108 PMID:27107132 MGI:6158728 MGI:6158784 NCBI chr 9:48,975,972...49,018,985
Ensembl chr 9:48,974,757...49,017,277
JBrowse link
G NOTCH2 notch receptor 2 involved_in ISO (PMID:16773578) BHF-UCL PMID:16773578 NCBI chr17:56,854,825...57,020,157
Ensembl chr17:56,860,429...57,020,857
JBrowse link
G ROBO1 roundabout guidance receptor 1 involved_in ISO (MGI:5913048|PMID:25691540) BHF-UCL PMID:25691540 MGI:5913048 NCBI chr31:8,082,363...8,594,623
Ensembl chr31:7,626,126...8,593,728
JBrowse link
G ROBO2 roundabout guidance receptor 2 involved_in ISO (MGI:5913048|PMID:25691540) BHF-UCL PMID:25691540 MGI:5913048 NCBI chr31:9,415,390...11,047,710
Ensembl chr31:9,419,026...11,022,392
JBrowse link
G SLIT2 slit guidance ligand 2 involved_in ISO (MGI:5913048|PMID:25691540) BHF-UCL PMID:25691540 MGI:5913048 NCBI chr 3:88,964,707...89,311,817
Ensembl chr 3:88,966,232...89,312,955
JBrowse link
G SMAD6 SMAD family member 6 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr30:30,938,908...31,014,259
Ensembl chr30:30,937,849...31,014,583
JBrowse link
G STRA6 signaling receptor and transporter of retinol STRA6 involved_in ISO (PMID:17273977) DFLAT PMID:17273977 NCBI chr30:37,331,834...37,359,449
Ensembl chr30:37,331,832...37,353,529
JBrowse link
G TGFB2 transforming growth factor beta 2 involved_in ISO (MGI:894212|PMID:9217007) BHF-UCL PMID:9217007 MGI:894212 NCBI chr38:13,430,832...13,511,655
Ensembl chr38:13,429,148...13,510,242
JBrowse link
sinoatrial valve morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MEF2C myocyte enhancer factor 2C involved_in ISS UniProt GO_REF:0000024 NCBI chr 3:19,778,997...19,948,203
Ensembl chr 3:19,779,007...19,943,852
JBrowse link
tricuspid valve formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HEY2 hes related family bHLH transcription factor with YRPW motif 2 acts_upstream_of_or_within ISO (MGI:3574376|PMID:15297376) MGI PMID:15297376 MGI:3574376 NCBI chr 1:64,630,656...64,646,546 JBrowse link
G ZFPM1 zinc finger protein, FOG family member 1 involved_in ISO (MGI:3583527|PMID:14614148) BHF-UCL PMID:14614148 MGI:3583527 NCBI chr 5:64,812,353...64,863,278 JBrowse link
tricuspid valve morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BMPR1A bone morphogenetic protein receptor type 1A involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 4:34,499,898...34,582,481
Ensembl chr 4:34,517,492...34,578,923
JBrowse link
G BMPR2 bone morphogenetic protein receptor type 2 involved_in ISO (MGI:3851675|PMID:19409885) BHF-UCL PMID:19409885 MGI:3851675 NCBI chr37:11,342,292...11,540,199
Ensembl chr37:11,342,384...11,533,024
JBrowse link
G HEY2 hes related family bHLH transcription factor with YRPW motif 2 involved_in ISO (MGI:2386835|PMID:12372254) BHF-UCL PMID:12372254 MGI:2386835 NCBI chr 1:64,630,656...64,646,546 JBrowse link
G TGFBR2 transforming growth factor beta receptor 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr23:13,886,869...13,946,480
Ensembl chr23:13,889,000...13,977,636
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17242
    developmental process 6629
      anatomical structure morphogenesis 2971
        heart valve morphogenesis 50
          aortic valve morphogenesis + 25
          apoptotic process involved in heart valve morphogenesis 0
          atrioventricular valve morphogenesis + 23
          cell proliferation involved in heart valve morphogenesis + 3
          coronary sinus valve morphogenesis + 1
          heart valve formation + 14
          pulmonary valve morphogenesis + 17
          sinoatrial valve morphogenesis + 1
          ventriculo bulbo valve morphogenesis + 0
Path 2
Term Annotations click to browse term
  biological_process 17242
    developmental process 6629
      anatomical structure development 6190
        multicellular organism development 5053
          system development 4366
            circulatory system development 1311
              heart development 707
                heart valve development 61
                  heart valve morphogenesis 50
                    aortic valve morphogenesis + 25
                    apoptotic process involved in heart valve morphogenesis 0
                    atrioventricular valve morphogenesis + 23
                    cell proliferation involved in heart valve morphogenesis + 3
                    coronary sinus valve morphogenesis + 1
                    heart valve formation + 14
                    pulmonary valve morphogenesis + 17
                    sinoatrial valve morphogenesis + 1
                    ventriculo bulbo valve morphogenesis + 0
paths to the root