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ONTOLOGY REPORT - ANNOTATIONS


Term:heart valve morphogenesis
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Accession:GO:0003179 term browser browse the term
Definition:The process in which the structure of a heart valve is generated and organized.
Synonyms:narrow_synonym: heart valve remodeling;   heart valve remodelling


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heart valve morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adamts9 ADAM metallopeptidase with thrombospondin type 1 motif 9 involved_in ISO (MGI:4452308|PMID:20096780) BHF-UCL PMID:20096780 MGI:4452308 NCBI chrNW_004955517:1,302,560...1,443,708
Ensembl chrNW_004955517:1,302,922...1,440,245
JBrowse link
G Fgfrl1 fibroblast growth factor receptor like 1 acts_upstream_of_or_within ISO (MGI:3848851|PMID:19383940) MGI PMID:19383940 MGI:3848851 NCBI chrNW_004955514:499,526...509,208
Ensembl chrNW_004955514:497,573...509,811
JBrowse link
G Mtor mechanistic target of rapamycin kinase acts_upstream_of_or_within ISO (MGI:5632243|PMID:25139234) MGI PMID:25139234 MGI:5632243 NCBI chrNW_004955486:2,487,642...2,599,694
Ensembl chrNW_004955486:2,487,642...2,599,694
JBrowse link
G Nfatc1 nuclear factor of activated T cells 1 acts_upstream_of_or_within ISO (MGI:1197816|PMID:9515963) MGI PMID:9515963 MGI:1197816 NCBI chrNW_004955402:62,558,392...62,674,347
Ensembl chrNW_004955402:62,558,286...62,674,457
JBrowse link
G Scx scleraxis bHLH transcription factor involved_in ISO (MGI:4413438|PMID:18802027) UniProt PMID:18802027 MGI:4413438 NCBI chrNW_004955454:2,886,981...2,888,829
Ensembl chrNW_004955454:2,886,981...2,888,829
JBrowse link
G Sox9 SRY-box transcription factor 9 acts_upstream_of_or_within ISO (MGI:3709829|PMID:17350610) MGI PMID:17350610 MGI:3709829 NCBI chrNW_004955478:941,684...945,563
Ensembl chrNW_004955478:940,177...945,563
JBrowse link
G Tgfb1 transforming growth factor beta 1 involved_in ISO (MGI:67103|PMID:8009224) BHF-UCL PMID:8009224 MGI:67103 NCBI chrNW_004955555:274,405...288,441
Ensembl chrNW_004955555:270,652...288,441
JBrowse link
G Tgfb2 transforming growth factor beta 2 involved_in
acts_upstream_of_or_within
ISO (MGI:3609313|PMID:11390347)
(MGI:5140242|PMID:21780244)
BHF-UCL
MGI
PMID:11390347 PMID:21780244 MGI:3609313 MGI:5140242 NCBI chrNW_004955406:174,949...249,248
Ensembl chrNW_004955406:172,814...249,248
JBrowse link
aortic valve morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp4 bone morphogenetic protein 4 involved_in ISO (MGI:3039210|PMID:15070745), (MGI:3814273|PMID:18924235) BHF-UCL PMID:15070745 PMID:18924235 MGI:3039210 MGI:3814273 NCBI chrNW_004955409:9,432,835...9,439,680
Ensembl chrNW_004955409:9,432,841...9,440,303
JBrowse link
G Efna1 ephrin A1 involved_in ISO (MGI:4847981|PMID:20960543) BHF-UCL PMID:20960543 MGI:4847981 NCBI chrNW_004955545:1,610,929...1,617,217
Ensembl chrNW_004955545:1,610,929...1,617,460
JBrowse link
G Emilin1 elastin microfibril interfacer 1 involved_in ISO (MGI:5605894|PMID:25056700) BHF-UCL PMID:25056700 MGI:5605894 NCBI chrNW_004955469:9,049,666...9,057,692
Ensembl chrNW_004955469:9,049,662...9,057,684
JBrowse link
G Gata3 GATA binding protein 3 involved_in ISO (MGI:3832106|PMID:18955134) UniProt PMID:18955134 MGI:3832106 NCBI chrNW_004955421:24,448,446...24,477,885
Ensembl chrNW_004955421:24,457,496...24,478,744
JBrowse link
G Gata4 GATA binding protein 4 involved_in ISO (PMID:29325903) BHF-UCL PMID:29325903 NCBI chrNW_004955403:52,958,318...53,029,267
Ensembl chrNW_004955403:52,987,644...53,029,267
JBrowse link
G Gata5 GATA binding protein 5 involved_in ISO (PMID:22641149), (PMID:24638895)
(MGI:5286818|PMID:21633169)
BHF-UCL PMID:21633169 PMID:22641149 PMID:24638895 MGI:5286818 NCBI chrNW_004955528:1,595,231...1,604,979
Ensembl chrNW_004955528:1,595,231...1,604,979
JBrowse link
G Hey1 hes related family bHLH transcription factor with YRPW motif 1 involved_in ISO (MGI:6158746|PMID:22110751) BHF-UCL PMID:22110751 MGI:6158746 NCBI chrNW_004955444:1,498,444...1,502,099
Ensembl chrNW_004955444:1,498,675...1,500,945
JBrowse link
G Hey2 hes related family bHLH transcription factor with YRPW motif 2 involved_in ISO (MGI:6158746|PMID:22110751) BHF-UCL PMID:22110751 MGI:6158746 NCBI chrNW_004955436:7,060,930...7,070,610
Ensembl chrNW_004955436:7,060,930...7,070,030
JBrowse link
G Nfatc1 nuclear factor of activated T cells 1 acts_upstream_of_or_within ISO (MGI:1197815|PMID:9515964) MGI PMID:9515964 MGI:1197815 NCBI chrNW_004955402:62,558,392...62,674,347
Ensembl chrNW_004955402:62,558,286...62,674,457
JBrowse link
G Nos3 nitric oxide synthase 3 involved_in ISO (MGI:3609262|PMID:10821808), (MGI:6158885|PMID:23583836)
(MGI:6158784|PMID:27107132)
BHF-UCL PMID:10821808 PMID:23583836 PMID:27107132 MGI:3609262 MGI:6158784 MGI:6158885 NCBI chrNW_004955491:5,438,228...5,457,308
Ensembl chrNW_004955491:5,438,010...5,460,814
JBrowse link
G Notch1 notch receptor 1 involved_in ISO (PMID:16025100), (PMID:17662764), (PMID:18593716)
(MGI:6158728|PMID:26491108)
(MGI:6158784|PMID:27107132), (MGI:6158885|PMID:23583836)
BHF-UCL PMID:16025100 PMID:17662764 PMID:18593716 PMID:23583836 PMID:26491108 More... MGI:6158728 MGI:6158784 MGI:6158885 NCBI chrNW_004955513:4,225,939...4,264,875
Ensembl chrNW_004955513:4,225,956...4,263,259
JBrowse link
G Rb1 RB transcriptional corepressor 1 involved_in ISO (MGI:6112863|PMID:29304157) BHF-UCL PMID:29304157 MGI:6112863 NCBI chrNW_004955431:1,960,765...2,124,576
Ensembl chrNW_004955431:1,960,661...2,124,576
JBrowse link
G Robo1 roundabout guidance receptor 1 involved_in ISO (MGI:5913048|PMID:25691540) BHF-UCL PMID:25691540 MGI:5913048 NCBI chrNW_004955407:12,593,911...13,485,723
Ensembl chrNW_004955407:13,107,235...13,487,053
JBrowse link
G Robo2 roundabout guidance receptor 2 involved_in ISO (MGI:5913048|PMID:25691540) BHF-UCL PMID:25691540 MGI:5913048 NCBI chrNW_004955407:14,301,689...15,549,561
Ensembl chrNW_004955407:14,305,498...14,842,790
JBrowse link
G Rock1 Rho associated coiled-coil containing protein kinase 1 involved_in ISO (PMID:26634652) BHF-UCL PMID:26634652 NCBI chrNW_004955402:9,752,101...9,864,317
Ensembl chrNW_004955402:9,750,730...9,864,317
JBrowse link
G Rock2 Rho associated coiled-coil containing protein kinase 2 involved_in ISO (PMID:26634652) BHF-UCL PMID:26634652 NCBI chrNW_004955487:5,856,190...5,972,408
Ensembl chrNW_004955487:5,859,204...5,972,401
JBrowse link
G Slit2 slit guidance ligand 2 involved_in ISO (MGI:5913048|PMID:25691540) BHF-UCL PMID:25691540 MGI:5913048 NCBI chrNW_004955480:3,982,977...4,314,160
Ensembl chrNW_004955480:3,984,586...4,313,908
JBrowse link
G Slit3 slit guidance ligand 3 involved_in ISO (MGI:5913048|PMID:25691540) BHF-UCL PMID:25691540 MGI:5913048 NCBI chrNW_004955408:21,719,487...22,322,958
Ensembl chrNW_004955408:21,722,632...22,322,917
JBrowse link
G Smad6 SMAD family member 6 involved_in ISO (PMID:22275001) BHF-UCL PMID:22275001 NCBI chrNW_004955450:9,005,332...9,070,790 JBrowse link
G Sox9 SRY-box transcription factor 9 involved_in ISO (PMID:22110751) BHF-UCL PMID:22110751 NCBI chrNW_004955478:941,684...945,563
Ensembl chrNW_004955478:940,177...945,563
JBrowse link
G Tbx20 T-box transcription factor 20 involved_in ISO (PMID:18275040), (PMID:18834961) BHF-UCL PMID:18275040 PMID:18834961 NCBI chrNW_004955460:7,794,313...7,856,906
Ensembl chrNW_004955460:7,794,313...7,856,906
JBrowse link
G Tgfb1 transforming growth factor beta 1 involved_in ISO (PMID:26634652)
(MGI:5921830|PMID:26634652)
BHF-UCL PMID:26634652 MGI:5921830 NCBI chrNW_004955555:274,405...288,441
Ensembl chrNW_004955555:270,652...288,441
JBrowse link
G Tie1 tyrosine kinase with immunoglobulin like and EGF like domains 1 involved_in ISO (MGI:6370101|PMID:31319059) BHF-UCL PMID:31319059 MGI:6370101 NCBI chrNW_004955537:2,894,913...2,914,284
Ensembl chrNW_004955537:2,894,914...2,914,284
JBrowse link
G Twist1 twist family bHLH transcription factor 1 involved_in ISO (PMID:20804746)
(MGI:4838344|PMID:20804746)
BHF-UCL PMID:20804746 MGI:4838344 NCBI chrNW_004955410:22,003,981...22,005,483 JBrowse link
atrioventricular valve formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gata4 GATA binding protein 4 involved_in ISO (MGI:4946551|PMID:21330551) BHF-UCL PMID:21330551 MGI:4946551 NCBI chrNW_004955403:52,958,318...53,029,267
Ensembl chrNW_004955403:52,987,644...53,029,267
JBrowse link
G Hey1 hes related family bHLH transcription factor with YRPW motif 1 involved_in ISO (MGI:3703467|PMID:17259303) BHF-UCL PMID:17259303 MGI:3703467 NCBI chrNW_004955444:1,498,444...1,502,099
Ensembl chrNW_004955444:1,498,675...1,500,945
JBrowse link
G Smad4 SMAD family member 4 involved_in ISO (MGI:4946551|PMID:21330551) BHF-UCL PMID:21330551 MGI:4946551 NCBI chrNW_004955402:35,956,080...36,001,746
Ensembl chrNW_004955402:35,961,165...35,994,538
JBrowse link
atrioventricular valve morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acvr1 activin A receptor type 1 involved_in ISO (MGI:3610266|PMID:16140292) BHF-UCL PMID:16140292 MGI:3610266 NCBI chrNW_004955449:15,587,958...15,706,432
Ensembl chrNW_004955449:15,640,230...15,708,694
JBrowse link
G Bmp2 bone morphogenetic protein 2 acts_upstream_of_or_within ISO (MGI:3611958|PMID:16314491) MGI PMID:16314491 MGI:3611958 NCBI chrNW_004955415:17,048,374...17,058,172
Ensembl chrNW_004955415:17,048,030...17,060,181
JBrowse link
G Bmpr2 bone morphogenetic protein receptor type 2 NOT|involved_in ISO (MGI:2429424|PMID:12441304) BHF-UCL PMID:12441304 MGI:2429424 NCBI chrNW_004955457:12,235,780...12,315,680
Ensembl chrNW_004955457:12,235,780...12,316,727
JBrowse link
G Ccn1 cellular communication network factor 1 acts_upstream_of_or_within ISO (MGI:3761425|PMID:17023674) MGI PMID:17023674 MGI:3761425 NCBI chrNW_004955423:8,416,498...8,419,029
Ensembl chrNW_004955423:8,413,725...8,419,166
JBrowse link
G Gata4 GATA binding protein 4 acts_upstream_of_or_within ISO (MGI:3833786|PMID:19084512) MGI PMID:19084512 MGI:3833786 NCBI chrNW_004955403:52,958,318...53,029,267
Ensembl chrNW_004955403:52,987,644...53,029,267
JBrowse link
G Hey1 hes related family bHLH transcription factor with YRPW motif 1 involved_in ISO (MGI:3783952|PMID:17303760) BHF-UCL PMID:17303760 MGI:3783952 NCBI chrNW_004955444:1,498,444...1,502,099
Ensembl chrNW_004955444:1,498,675...1,500,945
JBrowse link
G Heyl hes related family bHLH transcription factor with YRPW motif like involved_in ISO (MGI:3783952|PMID:17303760) BHF-UCL PMID:17303760 MGI:3783952 NCBI chrNW_004955452:17,137,066...17,152,714
Ensembl chrNW_004955452:17,134,770...17,152,924
JBrowse link
G Mdm2 MDM2 proto-oncogene acts_upstream_of_or_within ISO (MGI:5440773|PMID:22821713) MGI PMID:22821713 MGI:5440773 NCBI chrNW_004955458:15,264,028...15,287,290
Ensembl chrNW_004955458:15,263,739...15,286,808
JBrowse link
G Mdm4 MDM4 regulator of p53 acts_upstream_of_or_within ISO (MGI:5440773|PMID:22821713) MGI PMID:22821713 MGI:5440773 NCBI chrNW_004955406:40,346,617...40,387,977
Ensembl chrNW_004955406:40,346,588...40,387,977
JBrowse link
G Notch1 notch receptor 1 involved_in ISO (MGI:3027664|PMID:14701881), (MGI:5000164|PMID:21266778) BHF-UCL PMID:14701881 PMID:21266778 MGI:3027664 MGI:5000164 NCBI chrNW_004955513:4,225,939...4,264,875
Ensembl chrNW_004955513:4,225,956...4,263,259
JBrowse link
G Slit3 slit guidance ligand 3 involved_in ISO (MGI:5913048|PMID:25691540) BHF-UCL PMID:25691540 MGI:5913048 NCBI chrNW_004955408:21,719,487...22,322,958
Ensembl chrNW_004955408:21,722,632...22,322,917
JBrowse link
G Tbx5 T-box transcription factor 5 acts_upstream_of_or_within ISO (MGI:3833786|PMID:19084512) MGI PMID:19084512 MGI:3833786 NCBI chrNW_004955455:16,133,130...16,217,894
Ensembl chrNW_004955455:16,132,975...16,217,953
JBrowse link
G Tgfb2 transforming growth factor beta 2 involved_in ISO (MGI:894212|PMID:9217007) BHF-UCL PMID:9217007 MGI:894212 NCBI chrNW_004955406:174,949...249,248
Ensembl chrNW_004955406:172,814...249,248
JBrowse link
G Tgfbr2 transforming growth factor beta receptor 2 involved_in ISO (MGI:4821522|PMID:20652948) BHF-UCL PMID:20652948 MGI:4821522 NCBI chrNW_004955430:21,919,338...21,999,688
Ensembl chrNW_004955430:21,932,553...22,001,837
JBrowse link
G Zfpm1 zinc finger protein, FOG family member 1 involved_in ISO (MGI:3583527|PMID:14614148) BHF-UCL PMID:14614148 MGI:3583527 NCBI chrNW_004955541:2,461,690...2,495,614 JBrowse link
coronary sinus valve morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Notch1 notch receptor 1 involved_in ISO (MGI:6158728|PMID:26491108) BHF-UCL PMID:26491108 MGI:6158728 NCBI chrNW_004955513:4,225,939...4,264,875
Ensembl chrNW_004955513:4,225,956...4,263,259
JBrowse link
endocardial cushion to mesenchymal transition involved in heart valve formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Efna1 ephrin A1 involved_in ISO (MGI:4847981|PMID:20960543) BHF-UCL PMID:20960543 MGI:4847981 NCBI chrNW_004955545:1,610,929...1,617,217
Ensembl chrNW_004955545:1,610,929...1,617,460
JBrowse link
G Erg ETS transcription factor ERG acts_upstream_of_or_within ISO (MGI:5442628|PMID:22932696) MGI PMID:22932696 MGI:5442628 NCBI chrNW_004955407:37,372,471...37,613,674
Ensembl chrNW_004955407:37,369,641...37,542,751
JBrowse link
G Hey1 hes related family bHLH transcription factor with YRPW motif 1 acts_upstream_of_or_within ISO (MGI:3530185|PMID:15680351) MGI PMID:15680351 MGI:3530185 NCBI chrNW_004955444:1,498,444...1,502,099
Ensembl chrNW_004955444:1,498,675...1,500,945
JBrowse link
G Hey2 hes related family bHLH transcription factor with YRPW motif 2 acts_upstream_of_or_within ISO (MGI:3530185|PMID:15680351) MGI PMID:15680351 MGI:3530185 NCBI chrNW_004955436:7,060,930...7,070,610
Ensembl chrNW_004955436:7,060,930...7,070,030
JBrowse link
heart valve formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Scx scleraxis bHLH transcription factor involved_in ISO (MGI:4413438|PMID:18802027) UniProt PMID:18802027 MGI:4413438 NCBI chrNW_004955454:2,886,981...2,888,829
Ensembl chrNW_004955454:2,886,981...2,888,829
JBrowse link
G Sox9 SRY-box transcription factor 9 acts_upstream_of_or_within ISO (MGI:3709829|PMID:17350610) MGI PMID:17350610 MGI:3709829 NCBI chrNW_004955478:941,684...945,563
Ensembl chrNW_004955478:940,177...945,563
JBrowse link
mitral valve formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dchs1 dachsous cadherin-related 1 involved_in ISO (PMID:26258302) UniProt PMID:26258302 NCBI chrNW_004955414:22,331,590...22,365,761
Ensembl chrNW_004955414:22,332,059...22,351,576
JBrowse link
G Notch1 notch receptor 1 involved_in ISO (PMID:16025100) BHF-UCL PMID:16025100 NCBI chrNW_004955513:4,225,939...4,264,875
Ensembl chrNW_004955513:4,225,956...4,263,259
JBrowse link
G Zfpm1 zinc finger protein, FOG family member 1 involved_in ISO (MGI:3583527|PMID:14614148) BHF-UCL PMID:14614148 MGI:3583527 NCBI chrNW_004955541:2,461,690...2,495,614 JBrowse link
mitral valve morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acvr1 activin A receptor type 1 involved_in ISO (PMID:19506109) BHF-UCL PMID:19506109 NCBI chrNW_004955449:15,587,958...15,706,432
Ensembl chrNW_004955449:15,640,230...15,708,694
JBrowse link
G Bmpr1a bone morphogenetic protein receptor type 1A involved_in ISO (MGI:3653945|PMID:16037571) BHF-UCL PMID:16037571 MGI:3653945 NCBI chrNW_004955510:5,812,571...5,936,312
Ensembl chrNW_004955510:5,905,008...5,936,312
JBrowse link
G Bmpr2 bone morphogenetic protein receptor type 2 involved_in ISO (MGI:3851675|PMID:19409885) BHF-UCL PMID:19409885 MGI:3851675 NCBI chrNW_004955457:12,235,780...12,315,680
Ensembl chrNW_004955457:12,235,780...12,316,727
JBrowse link
G Dchs1 dachsous cadherin-related 1 involved_in
acts_upstream_of_or_within
ISO (MGI:5694502|PMID:26258302) MGI PMID:26258302 MGI:5694502 NCBI chrNW_004955414:22,331,590...22,365,761
Ensembl chrNW_004955414:22,332,059...22,351,576
JBrowse link
G Efna1 ephrin A1 involved_in ISO (MGI:4847981|PMID:20960543) BHF-UCL PMID:20960543 MGI:4847981 NCBI chrNW_004955545:1,610,929...1,617,217
Ensembl chrNW_004955545:1,610,929...1,617,460
JBrowse link
G Smad6 SMAD family member 6 involved_in ISO (MGI:1352979|PMID:10655064) BHF-UCL PMID:10655064 MGI:1352979 NCBI chrNW_004955450:9,005,332...9,070,790 JBrowse link
G Sox4 SRY-box transcription factor 4 involved_in ISO (MGI:3603061|PMID:16109771) BHF-UCL PMID:16109771 MGI:3603061 NCBI chrNW_004955483:5,076,664...5,077,059 JBrowse link
G Twist1 twist family bHLH transcription factor 1 involved_in ISO (MGI:4838344|PMID:20804746) BHF-UCL PMID:20804746 MGI:4838344 NCBI chrNW_004955410:22,003,981...22,005,483 JBrowse link
negative regulation of cell proliferation involved in heart valve morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmpr2 bone morphogenetic protein receptor type 2 involved_in ISO (MGI:3851675|PMID:19409885) BHF-UCL PMID:19409885 MGI:3851675 NCBI chrNW_004955457:12,235,780...12,315,680
Ensembl chrNW_004955457:12,235,780...12,316,727
JBrowse link
G Notch1 notch receptor 1 involved_in ISO (MGI:6158728|PMID:26491108) BHF-UCL PMID:26491108 MGI:6158728 NCBI chrNW_004955513:4,225,939...4,264,875
Ensembl chrNW_004955513:4,225,956...4,263,259
JBrowse link
positive regulation of cell proliferation involved in heart valve morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Smad4 SMAD family member 4 involved_in ISO (MGI:4946551|PMID:21330551) BHF-UCL PMID:21330551 MGI:4946551 NCBI chrNW_004955402:35,956,080...36,001,746
Ensembl chrNW_004955402:35,961,165...35,994,538
JBrowse link
positive regulation of endocardial cushion to mesenchymal transition involved in heart valve formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Twist1 twist family bHLH transcription factor 1 involved_in ISO (MGI:4838344|PMID:20804746) BHF-UCL PMID:20804746 MGI:4838344 NCBI chrNW_004955410:22,003,981...22,005,483 JBrowse link
pulmonary valve formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gja5 gap junction protein alpha 5 involved_in ISO (PMID:22199024) BHF-UCL PMID:22199024 NCBI chrNW_004955568:635,319...652,692
Ensembl chrNW_004955568:635,042...653,349
JBrowse link
G Tbx20 T-box transcription factor 20 involved_in ISO (MGI:3604925|PMID:15843409) BHF-UCL PMID:15843409 MGI:3604925 NCBI chrNW_004955460:7,794,313...7,856,906
Ensembl chrNW_004955460:7,794,313...7,856,906
JBrowse link
pulmonary valve morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp4 bone morphogenetic protein 4 involved_in ISO (MGI:3039210|PMID:15070745), (MGI:3814273|PMID:18924235) BHF-UCL PMID:15070745 PMID:18924235 MGI:3039210 MGI:3814273 NCBI chrNW_004955409:9,432,835...9,439,680
Ensembl chrNW_004955409:9,432,841...9,440,303
JBrowse link
G Hey1 hes related family bHLH transcription factor with YRPW motif 1 involved_in ISO (MGI:3783952|PMID:17303760) BHF-UCL PMID:17303760 MGI:3783952 NCBI chrNW_004955444:1,498,444...1,502,099
Ensembl chrNW_004955444:1,498,675...1,500,945
JBrowse link
G Hey2 hes related family bHLH transcription factor with YRPW motif 2 involved_in ISO (MGI:2386835|PMID:12372254) BHF-UCL PMID:12372254 MGI:2386835 NCBI chrNW_004955436:7,060,930...7,070,610
Ensembl chrNW_004955436:7,060,930...7,070,030
JBrowse link
G Heyl hes related family bHLH transcription factor with YRPW motif like involved_in ISO (MGI:3783952|PMID:17303760) BHF-UCL PMID:17303760 MGI:3783952 NCBI chrNW_004955452:17,137,066...17,152,714
Ensembl chrNW_004955452:17,134,770...17,152,924
JBrowse link
G Jag1 jagged canonical Notch ligand 1 involved_in ISO (PMID:20437614), (PMID:9207787) BHF-UCL PMID:9207787 PMID:20437614 NCBI chrNW_004955415:20,490,414...20,526,068
Ensembl chrNW_004955415:20,490,414...20,527,917
JBrowse link
G Nfatc1 nuclear factor of activated T cells 1 acts_upstream_of_or_within ISO (MGI:1197815|PMID:9515964) MGI PMID:9515964 MGI:1197815 NCBI chrNW_004955402:62,558,392...62,674,347
Ensembl chrNW_004955402:62,558,286...62,674,457
JBrowse link
G Nos3 nitric oxide synthase 3 involved_in ISO (MGI:6158784|PMID:27107132) BHF-UCL PMID:27107132 MGI:6158784 NCBI chrNW_004955491:5,438,228...5,457,308
Ensembl chrNW_004955491:5,438,010...5,460,814
JBrowse link
G Notch1 notch receptor 1 involved_in ISO (PMID:16025100)
(MGI:6158728|PMID:26491108)
(MGI:6158784|PMID:27107132)
BHF-UCL PMID:16025100 PMID:26491108 PMID:27107132 MGI:6158728 MGI:6158784 NCBI chrNW_004955513:4,225,939...4,264,875
Ensembl chrNW_004955513:4,225,956...4,263,259
JBrowse link
G Notch2 notch receptor 2 involved_in ISO (PMID:16773578) BHF-UCL PMID:16773578 NCBI chrNW_004955568:1,660,357...1,812,285
Ensembl chrNW_004955568:1,660,731...1,809,173
JBrowse link
G Robo1 roundabout guidance receptor 1 involved_in ISO (MGI:5913048|PMID:25691540) BHF-UCL PMID:25691540 MGI:5913048 NCBI chrNW_004955407:12,593,911...13,485,723
Ensembl chrNW_004955407:13,107,235...13,487,053
JBrowse link
G Robo2 roundabout guidance receptor 2 involved_in ISO (MGI:5913048|PMID:25691540) BHF-UCL PMID:25691540 MGI:5913048 NCBI chrNW_004955407:14,301,689...15,549,561
Ensembl chrNW_004955407:14,305,498...14,842,790
JBrowse link
G Slit2 slit guidance ligand 2 involved_in ISO (MGI:5913048|PMID:25691540) BHF-UCL PMID:25691540 MGI:5913048 NCBI chrNW_004955480:3,982,977...4,314,160
Ensembl chrNW_004955480:3,984,586...4,313,908
JBrowse link
G Smad6 SMAD family member 6 involved_in ISO (MGI:1352979|PMID:10655064) BHF-UCL PMID:10655064 MGI:1352979 NCBI chrNW_004955450:9,005,332...9,070,790 JBrowse link
G Stra6 signaling receptor and transporter of retinol STRA6 involved_in ISO (PMID:17273977) DFLAT PMID:17273977 NCBI chrNW_004955450:3,579,081...3,602,538
Ensembl chrNW_004955450:3,580,662...3,602,600
JBrowse link
G Tgfb2 transforming growth factor beta 2 involved_in ISO (MGI:894212|PMID:9217007) BHF-UCL PMID:9217007 MGI:894212 NCBI chrNW_004955406:174,949...249,248
Ensembl chrNW_004955406:172,814...249,248
JBrowse link
sinoatrial valve morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mef2c myocyte enhancer factor 2C involved_in ISO (MGI:3830899|PMID:16680724) UniProt PMID:16680724 MGI:3830899 NCBI chrNW_004955418:22,537,388...22,701,434
Ensembl chrNW_004955418:22,537,285...22,701,434
JBrowse link
tricuspid valve formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hey2 hes related family bHLH transcription factor with YRPW motif 2 acts_upstream_of_or_within ISO (MGI:3574376|PMID:15297376) MGI PMID:15297376 MGI:3574376 NCBI chrNW_004955436:7,060,930...7,070,610
Ensembl chrNW_004955436:7,060,930...7,070,030
JBrowse link
G Zfpm1 zinc finger protein, FOG family member 1 involved_in ISO (MGI:3583527|PMID:14614148) BHF-UCL PMID:14614148 MGI:3583527 NCBI chrNW_004955541:2,461,690...2,495,614 JBrowse link
tricuspid valve morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmpr1a bone morphogenetic protein receptor type 1A involved_in ISO (MGI:3653945|PMID:16037571) BHF-UCL PMID:16037571 MGI:3653945 NCBI chrNW_004955510:5,812,571...5,936,312
Ensembl chrNW_004955510:5,905,008...5,936,312
JBrowse link
G Bmpr2 bone morphogenetic protein receptor type 2 involved_in ISO (MGI:3851675|PMID:19409885) BHF-UCL PMID:19409885 MGI:3851675 NCBI chrNW_004955457:12,235,780...12,315,680
Ensembl chrNW_004955457:12,235,780...12,316,727
JBrowse link
G Hey2 hes related family bHLH transcription factor with YRPW motif 2 involved_in ISO (MGI:2386835|PMID:12372254) BHF-UCL PMID:12372254 MGI:2386835 NCBI chrNW_004955436:7,060,930...7,070,610
Ensembl chrNW_004955436:7,060,930...7,070,030
JBrowse link
G Tgfbr2 transforming growth factor beta receptor 2 involved_in ISO (MGI:4821522|PMID:20652948) BHF-UCL PMID:20652948 MGI:4821522 NCBI chrNW_004955430:21,919,338...21,999,688
Ensembl chrNW_004955430:21,932,553...22,001,837
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12234
    developmental process 5795
      anatomical structure morphogenesis 2566
        heart valve morphogenesis 49
          aortic valve morphogenesis + 24
          apoptotic process involved in heart valve morphogenesis 0
          atrioventricular valve morphogenesis + 23
          cell proliferation involved in heart valve morphogenesis + 3
          coronary sinus valve morphogenesis + 1
          heart valve formation + 14
          pulmonary valve morphogenesis + 17
          sinoatrial valve morphogenesis + 1
          ventriculo bulbo valve morphogenesis + 0
Path 2
Term Annotations click to browse term
  biological_process 12234
    developmental process 5795
      anatomical structure development 5449
        multicellular organism development 4501
          system development 3897
            circulatory system development 1122
              heart development 645
                heart valve development 60
                  heart valve morphogenesis 49
                    aortic valve morphogenesis + 24
                    apoptotic process involved in heart valve morphogenesis 0
                    atrioventricular valve morphogenesis + 23
                    cell proliferation involved in heart valve morphogenesis + 3
                    coronary sinus valve morphogenesis + 1
                    heart valve formation + 14
                    pulmonary valve morphogenesis + 17
                    sinoatrial valve morphogenesis + 1
                    ventriculo bulbo valve morphogenesis + 0
paths to the root