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Term:atrioventricular bundle cell differentiation
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Accession:GO:0003167 term browser browse the term
Definition:The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a cell of the atrioventricular bundle. These cells are specialized cardiomyocytes that transmit signals from the AV node to the cardiac Purkinje fibers.
Synonyms:exact_synonym: AV bundle cell differentiation

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atrioventricular bundle cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Irx3 iroquois homeobox 3 involved_in ISO (MGI:6101691|PMID:26786475) RGD PMID:26786475 MGI:6101691 NCBI chr19:15,211,882...15,215,323
Ensembl chr19:15,211,878...15,215,317
JBrowse link
G Tbx3 T-box transcription factor 3 acts_upstream_of_or_within ISO MGI:3710254 (MGI:3847383|PMID:18467625) RGD PMID:18467625 MGI:3847383 NCBI chr12:36,879,924...36,894,849
Ensembl chr12:36,881,445...36,893,708
JBrowse link
G Tbx5 T-box transcription factor 5 involved_in IEA
PMID:15289437 GO_REF:0000107 MGI:3051695 NCBI chr12:36,686,344...36,739,253
Ensembl chr12:36,688,014...36,734,885
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19390
    developmental process 6778
      cellular developmental process 4482
        cell differentiation 4387
          cardiocyte differentiation 187
            cardiac muscle cell differentiation 150
              His-Purkinje system cell differentiation 4
                atrioventricular bundle cell differentiation 3
Path 2
Term Annotations click to browse term
  biological_process 19390
    developmental process 6778
      anatomical structure development 6203
        multicellular organism development 5641
          system development 5310
            animal organ development 4070
              heart development 697
                cardiac muscle tissue development 261
                  cardiac conduction system development 20
                    His-Purkinje system development 6
                      bundle of His development 5
                        atrioventricular bundle cell differentiation 3
paths to the root