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ONTOLOGY REPORT - ANNOTATIONS


Term:bundle of His development
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Accession:GO:0003166 term browser browse the term
Definition:The process whose specific outcome is the progression of the bundle of His over time, from its formation to the mature structure. The bundle of His is part of the His-Purkinje system that transmits signals from the AV node to the cardiac Purkinje fibers.
Synonyms:exact_synonym: atrioventricular bundle development



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bundle of His development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Id2 inhibitor of DNA binding 2 acts_upstream_of_or_within ISO MGI:2384134 (MGI:3716040|PMID:17604724) RGD PMID:17604724 MGI:3716040 NCBI chr 6:41,740,556...41,742,393
Ensembl chr 6:41,728,946...41,744,400
JBrowse link
G Nkx2-5 NK2 homeobox 5 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:102541 (MGI:3716040|PMID:17604724)
Ensembl
RGD
PMID:17604724 GO_REF:0000107 MGI:3716040 NCBI chr10:16,340,428...16,347,004
Ensembl chr10:16,344,159...16,346,934
JBrowse link
G Tbx5 T-box transcription factor 5 acts_upstream_of_or_within
involved_in
ISO MGI:97350 (MGI:3716040|PMID:17604724)
(MGI:5449667|PMID:22728936)
RGD PMID:17604724 PMID:22728936 MGI:3716040 MGI:5449667 NCBI chr12:36,686,344...36,739,253
Ensembl chr12:36,688,014...36,734,885
JBrowse link
atrioventricular bundle cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Irx3 iroquois homeobox 3 involved_in ISO (MGI:6101691|PMID:26786475) RGD PMID:26786475 MGI:6101691 NCBI chr19:15,211,882...15,215,323
Ensembl chr19:15,211,878...15,215,317
JBrowse link
G Tbx3 T-box transcription factor 3 acts_upstream_of_or_within ISO MGI:3710254 (MGI:3847383|PMID:18467625) RGD PMID:18467625 MGI:3847383 NCBI chr12:36,879,924...36,894,849
Ensembl chr12:36,881,445...36,893,708
JBrowse link
G Tbx5 T-box transcription factor 5 involved_in IEA
ISO
GO_REF:0000107
(MGI:3051695|PMID:15289437)
Ensembl
RGD
PMID:15289437 GO_REF:0000107 MGI:3051695 NCBI chr12:36,686,344...36,739,253
Ensembl chr12:36,688,014...36,734,885
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19497
    developmental process 6889
      anatomical structure development 6306
        animal organ development 4130
          heart development 698
            cardiac muscle tissue development 260
              ventricular cardiac muscle tissue development 63
                bundle of His development 5
                  atrioventricular bundle cell differentiation 3
Path 2
Term Annotations click to browse term
  biological_process 19497
    developmental process 6889
      anatomical structure development 6306
        multicellular organism development 5727
          system development 5373
            circulatory system development 1244
              heart development 698
                cardiac muscle tissue development 260
                  cardiac conduction system development 20
                    His-Purkinje system development 6
                      bundle of His development 5
                        atrioventricular bundle cell differentiation 3
paths to the root