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ONTOLOGY REPORT - ANNOTATIONS


Term:His-Purkinje system development
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Accession:GO:0003164 term browser browse the term
Definition:The process whose specific outcome is the progression of the His-Purkinje system over time, from its formation to the mature structure. The His-Purkinje system receives signals from the AV node and is composed of the fibers that regulate cardiac muscle contraction in the ventricles.


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atrioventricular bundle cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Irx3 iroquois homeobox 3 involved_in ISO (MGI:6101691|PMID:26786475) BHF-UCL PMID:26786475 MGI:6101691 NCBI chrNW_004936475:6,810,678...6,813,186 JBrowse link
G Tbx3 T-box transcription factor 3 acts_upstream_of_or_within ISO (MGI:3847383|PMID:18467625) MGI PMID:18467625 MGI:3847383 NCBI chrNW_004936558:7,230,361...7,243,651 JBrowse link
G Tbx5 T-box transcription factor 5 involved_in ISO (MGI:3051695|PMID:15289437) BHF-UCL PMID:15289437 MGI:3051695 NCBI chrNW_004936558:7,408,229...7,454,897 JBrowse link
bundle of His development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Id2 inhibitor of DNA binding 2 acts_upstream_of_or_within ISO (MGI:3716040|PMID:17604724) MGI PMID:17604724 MGI:3716040 NCBI chrNW_004936532:5,236,175...5,238,689 JBrowse link
G Nkx2-5 NK2 homeobox 5 acts_upstream_of_or_within ISO (MGI:3716040|PMID:17604724) MGI PMID:17604724 MGI:3716040 NCBI chrNW_004936609:2,406,004...2,408,980 JBrowse link
G Tbx5 T-box transcription factor 5 involved_in
acts_upstream_of_or_within
ISO (MGI:5449667|PMID:22728936)
(MGI:3716040|PMID:17604724)
BHF-UCL
MGI
PMID:17604724 PMID:22728936 MGI:3716040 MGI:5449667 NCBI chrNW_004936558:7,408,229...7,454,897 JBrowse link
His-Purkinje system cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Irx3 iroquois homeobox 3 involved_in ISO (MGI:6101691|PMID:26786475) BHF-UCL PMID:26786475 MGI:6101691 NCBI chrNW_004936475:6,810,678...6,813,186 JBrowse link
Purkinje myocyte development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dsg2 desmoglein 2 involved_in ISO (PMID:16505173) BHF-UCL PMID:16505173 NCBI chrNW_004936682:1,676,301...1,725,132 JBrowse link
G Irx3 iroquois homeobox 3 involved_in ISO (MGI:6101691|PMID:26786475) BHF-UCL PMID:26786475 MGI:6101691 NCBI chrNW_004936475:6,810,678...6,813,186 JBrowse link
Purkinje myocyte differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nkx2-5 NK2 homeobox 5 acts_upstream_of_or_within ISO (MGI:3785685|PMID:17250822) MGI PMID:17250822 MGI:3785685 NCBI chrNW_004936609:2,406,004...2,408,980 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12173
    developmental process 5742
      anatomical structure development 5369
        animal organ development 3566
          heart development 641
            cardiac muscle tissue development 245
              ventricular cardiac muscle tissue development 60
                His-Purkinje system development 6
                  His-Purkinje system cell differentiation + 4
                  Purkinje myocyte development + 3
                  bundle of His development + 5
Path 2
Term Annotations click to browse term
  biological_process 12173
    developmental process 5742
      anatomical structure development 5369
        multicellular organism development 4919
          system development 4631
            circulatory system development 1125
              heart development 641
                cardiac muscle tissue development 245
                  ventricular cardiac muscle tissue development 60
                    His-Purkinje system development 6
                      His-Purkinje system cell differentiation + 4
                      Purkinje myocyte development + 3
                      bundle of His development + 5
paths to the root