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ONTOLOGY REPORT - ANNOTATIONS


Term:His-Purkinje system development
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Accession:GO:0003164 term browser browse the term
Definition:The process whose specific outcome is the progression of the His-Purkinje system over time, from its formation to the mature structure. The His-Purkinje system receives signals from the AV node and is composed of the fibers that regulate cardiac muscle contraction in the ventricles.



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atrioventricular bundle cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Irx3 iroquois homeobox 3 involved_in ISO (MGI:6101691|PMID:26786475) RGD PMID:26786475 MGI:6101691 NCBI chr19:15,211,882...15,215,323
Ensembl chr19:15,211,878...15,215,317
JBrowse link
G Tbx3 T-box transcription factor 3 acts_upstream_of_or_within ISO MGI:3710254 (MGI:3847383|PMID:18467625) RGD PMID:18467625 MGI:3847383 NCBI chr12:36,879,924...36,894,849
Ensembl chr12:36,881,445...36,893,708
JBrowse link
G Tbx5 T-box transcription factor 5 involved_in IEA
ISO
GO_REF:0000107
(MGI:3051695|PMID:15289437)
Ensembl
RGD
PMID:15289437 GO_REF:0000107 MGI:3051695 NCBI chr12:36,686,344...36,739,253
Ensembl chr12:36,688,014...36,734,885
JBrowse link
bundle of His development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Id2 inhibitor of DNA binding 2 acts_upstream_of_or_within ISO MGI:2384134 (MGI:3716040|PMID:17604724) RGD PMID:17604724 MGI:3716040 NCBI chr 6:41,740,556...41,742,393
Ensembl chr 6:41,728,946...41,744,400
JBrowse link
G Nkx2-5 NK2 homeobox 5 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:102541 (MGI:3716040|PMID:17604724)
Ensembl
RGD
PMID:17604724 GO_REF:0000107 MGI:3716040 NCBI chr10:16,340,428...16,347,004
Ensembl chr10:16,344,159...16,346,934
JBrowse link
G Tbx5 T-box transcription factor 5 acts_upstream_of_or_within
involved_in
ISO MGI:97350 (MGI:3716040|PMID:17604724)
(MGI:5449667|PMID:22728936)
RGD PMID:17604724 PMID:22728936 MGI:3716040 MGI:5449667 NCBI chr12:36,686,344...36,739,253
Ensembl chr12:36,688,014...36,734,885
JBrowse link
His-Purkinje system cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Irx3 iroquois homeobox 3 involved_in ISO (MGI:6101691|PMID:26786475) RGD PMID:26786475 MGI:6101691 NCBI chr19:15,211,882...15,215,323
Ensembl chr19:15,211,878...15,215,317
JBrowse link
Purkinje myocyte development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dsg2 desmoglein 2 involved_in ISO (PMID:16505173) RGD PMID:16505173 NCBI chr18:11,846,207...11,904,630
Ensembl chr18:11,846,183...11,904,156
JBrowse link
G Irx3 iroquois homeobox 3 involved_in ISO (MGI:6101691|PMID:26786475) RGD PMID:26786475 MGI:6101691 NCBI chr19:15,211,882...15,215,323
Ensembl chr19:15,211,878...15,215,317
JBrowse link
Purkinje myocyte differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nkx2-5 NK2 homeobox 5 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:1857618 (MGI:3785685|PMID:17250822)
Ensembl
RGD
PMID:17250822 GO_REF:0000107 MGI:3785685 NCBI chr10:16,340,428...16,347,004
Ensembl chr10:16,344,159...16,346,934
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19390
    developmental process 6778
      anatomical structure development 6203
        animal organ development 4070
          heart development 697
            cardiac muscle tissue development 261
              ventricular cardiac muscle tissue development 63
                His-Purkinje system development 6
                  His-Purkinje system cell differentiation + 4
                  Purkinje myocyte development + 3
                  bundle of His development + 5
Path 2
Term Annotations click to browse term
  biological_process 19390
    developmental process 6778
      anatomical structure development 6203
        multicellular organism development 5641
          system development 5310
            circulatory system development 1241
              heart development 697
                cardiac muscle tissue development 261
                  ventricular cardiac muscle tissue development 63
                    His-Purkinje system development 6
                      His-Purkinje system cell differentiation + 4
                      Purkinje myocyte development + 3
                      bundle of His development + 5
paths to the root