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ONTOLOGY REPORT - ANNOTATIONS


Term:His-Purkinje system development
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Accession:GO:0003164 term browser browse the term
Definition:The process whose specific outcome is the progression of the His-Purkinje system over time, from its formation to the mature structure. The His-Purkinje system receives signals from the AV node and is composed of the fibers that regulate cardiac muscle contraction in the ventricles.



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atrioventricular bundle cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IRX3 iroquois homeobox 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:31,044,919...31,049,067
Ensembl chr 6:31,046,098...31,048,822
JBrowse link
G TBX3 T-box transcription factor 3 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:3847383|PMID:18467625) Ensembl
MGI
PMID:18467625 GO_REF:0000107 MGI:3847383 NCBI chr14:37,582,704...37,596,767
Ensembl chr14:37,582,822...37,596,767
JBrowse link
G TBX5 T-box transcription factor 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:37,772,205...37,826,015
Ensembl chr14:37,773,605...37,824,400
JBrowse link
bundle of His development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ID2 inhibitor of DNA binding 2 acts_upstream_of_or_within ISO (MGI:3716040|PMID:17604724) MGI PMID:17604724 MGI:3716040 NCBI chr 3:127,500,759...127,503,207
Ensembl chr 3:127,500,759...127,503,257
JBrowse link
G NKX2-5 NK2 homeobox 5 acts_upstream_of_or_within ISO (MGI:3716040|PMID:17604724) MGI PMID:17604724 MGI:3716040 NCBI chr16:51,086,014...51,089,165
Ensembl chr16:51,086,011...51,089,165
JBrowse link
G TBX5 T-box transcription factor 5 acts_upstream_of_or_within
involved_in
ISO (MGI:3716040|PMID:17604724)
(MGI:5449667|PMID:22728936)
MGI
BHF-UCL
PMID:17604724 PMID:22728936 MGI:3716040 MGI:5449667 NCBI chr14:37,772,205...37,826,015
Ensembl chr14:37,773,605...37,824,400
JBrowse link
His-Purkinje system cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IRX3 iroquois homeobox 3 involved_in ISO (MGI:6101691|PMID:26786475) BHF-UCL PMID:26786475 MGI:6101691 NCBI chr 6:31,044,919...31,049,067
Ensembl chr 6:31,046,098...31,048,822
JBrowse link
Purkinje myocyte development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DSG2 desmoglein 2 involved_in ISO (PMID:16505173) BHF-UCL PMID:16505173 NCBI chr 6:115,400,223...115,453,763
Ensembl chr 6:115,400,252...115,452,473
JBrowse link
G IRX3 iroquois homeobox 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:31,044,919...31,049,067
Ensembl chr 6:31,046,098...31,048,822
JBrowse link
Purkinje myocyte differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NKX2-5 NK2 homeobox 5 acts_upstream_of_or_within ISO (MGI:3785685|PMID:17250822) MGI PMID:17250822 MGI:3785685 NCBI chr16:51,086,014...51,089,165
Ensembl chr16:51,086,011...51,089,165
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16581
    developmental process 6319
      anatomical structure development 5836
        animal organ development 3835
          heart development 679
            cardiac muscle tissue development 256
              ventricular cardiac muscle tissue development 62
                His-Purkinje system development 6
                  His-Purkinje system cell differentiation + 4
                  Purkinje myocyte development + 3
                  bundle of His development + 5
Path 2
Term Annotations click to browse term
  biological_process 16581
    developmental process 6319
      anatomical structure development 5836
        multicellular organism development 5309
          system development 5000
            circulatory system development 1203
              heart development 679
                cardiac muscle tissue development 256
                  ventricular cardiac muscle tissue development 62
                    His-Purkinje system development 6
                      His-Purkinje system cell differentiation + 4
                      Purkinje myocyte development + 3
                      bundle of His development + 5
paths to the root