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ONTOLOGY REPORT - ANNOTATIONS

Term:morphogenesis of an endothelium
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Accession:GO:0003159 term browser browse the term
Definition:The process in which the anatomical structure of an endothelium is generated and organized. Endothelium refers to the layer of cells lining blood vessels, lymphatics, the heart, and serous cavities, and is derived from bone marrow or mesoderm. Corneal endothelium is a special case, derived from neural crest cells.


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blood vessel lumenization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dll4 delta like canonical Notch ligand 4 involved_in IEA
ISO 		GO_REF:0000107
(PMID:15466160) 		Ensembl
RGD		 PMID:15466160 GO_REF:0000107 NCBI chr 3:106,317,114...106,327,004
Ensembl chr 3:106,316,986...106,326,931 		JBrowse link
G Rbpj recombination signal binding protein for immunoglobulin kappa J region involved_in ISO (PMID:15466160) RGD PMID:15466160 NCBI chr14:57,338,493...57,523,330
Ensembl chr14:57,338,507...57,523,353 		JBrowse link
endothelial tube lumen extension term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rhoa ras homolog family member A acts_upstream_of_or_within ISO
IEA 		UniProtKB:Q9Y3M8 (PMID:20208559)
GO_REF:0000107 		RGD
Ensembl		 PMID:20208559 GO_REF:0000107 NCBI chr 8:108,991,926...109,025,746
Ensembl chr 8:108,991,954...109,025,746 		JBrowse link
G Stard13 StAR-related lipid transfer domain containing 13 acts_upstream_of_or_within ISO
IEA 		UniProtKB:P61586 (PMID:20208559)
GO_REF:0000107 		RGD
Ensembl		 PMID:20208559 GO_REF:0000107 NCBI chr12:566,282...959,372
Ensembl chr12:566,310...959,421 		JBrowse link
endothelial tube morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acvrl1 activin A receptor like type 1 involved_in ISO (PMID:19592636) RGD PMID:19592636 NCBI chr 7:132,239,200...132,256,592
Ensembl chr 7:132,239,729...132,256,591 		JBrowse link
G Bsg basigin involved_in ISO
ISS 		(PMID:19837976)
GO_REF:0000024 		RGD
UniProt		 PMID:19837976 GO_REF:0000024 NCBI chr 7:9,993,170...10,000,387
Ensembl chr 7:9,993,170...10,000,387 		JBrowse link
G Ccm2 CCM2 scaffold protein acts_upstream_of_or_within ISO
IEA 		(PMID:19151727)
GO_REF:0000107 		RGD
Ensembl		 PMID:19151727 GO_REF:0000107 NCBI chr14:81,418,418...81,464,114
Ensembl chr14:81,418,236...81,464,116 		JBrowse link
G Csnk2b casein kinase 2 beta involved_in ISO (PMID:19592636) RGD PMID:19592636 NCBI chr20:3,700,363...3,705,331
Ensembl chr20:3,698,733...3,707,133 		JBrowse link
G Ctnnb1 catenin beta 1 involved_in ISO
IEA
ISS 		(PMID:20123964)
GO_REF:0000107
GO_REF:0000024 		RGD
Ensembl
UniProt		 PMID:20123964 GO_REF:0000024 GO_REF:0000107 NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111 		JBrowse link
G Cxcr4 C-X-C motif chemokine receptor 4 IMP RGD PMID:24955809 RGD:11352686 NCBI chr13:40,077,976...40,081,883
Ensembl chr13:40,077,976...40,081,883 		JBrowse link
G Kdr kinase insert domain receptor IMP RGD PMID:25942475 RGD:126925211 NCBI chr14:32,217,871...32,261,018
Ensembl chr14:32,217,871...32,261,018 		JBrowse link
G Mir21 microRNA 21 involved_in ISO (PMID:21347332) RGD PMID:21347332 NCBI chr10:71,405,257...71,405,348
Ensembl chr10:71,405,257...71,405,348 		JBrowse link
G Rhob ras homolog family member B involved_in ISO
IEA 		(PMID:21347332)
GO_REF:0000107 		RGD
Ensembl		 PMID:21347332 GO_REF:0000107 NCBI chr 6:37,083,030...37,085,204
Ensembl chr 6:31,363,548...31,366,108 		JBrowse link
positive regulation of endothelial tube morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alox12 arachidonate 12-lipoxygenase, 12S type IMP RGD PMID:10733500 RGD:2313864 NCBI chr10:54,958,263...54,970,542
Ensembl chr10:54,958,271...54,970,542 		JBrowse link
G Itgax integrin subunit alpha X involved_in ISO
IEA 		(PMID:30873824)
GO_REF:0000107 		RGD
Ensembl		 PMID:30873824 GO_REF:0000107 NCBI chr 1:182,709,653...182,740,709
Ensembl chr 1:182,719,609...182,740,698 		JBrowse link
G Lcn2 lipocalin 2 IDA RGD PMID:25557118 RGD:126790477 NCBI chr 3:15,680,688...15,684,033
Ensembl chr 3:15,680,687...15,684,095 		JBrowse link
G Mir21 microRNA 21 IMP RGD PMID:31759996 RGD:41410819 NCBI chr10:71,405,257...71,405,348
Ensembl chr10:71,405,257...71,405,348 		JBrowse link
regulation of endothelial tube morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adamts12 ADAM metallopeptidase with thrombospondin type 1 motif, 12 involved_in ISO
IEA 		(PMID:17895370)
GO_REF:0000107 		RGD
Ensembl		 PMID:17895370 GO_REF:0000107 NCBI chr 2:60,032,873...60,327,629
Ensembl chr 2:60,032,873...60,327,629 		JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 involved_in ISO
IEA 		(PMID:16484616)
GO_REF:0000107 		RGD
Ensembl		 PMID:16484616 GO_REF:0000107 NCBI chr14:15,704,772...15,706,969
Ensembl chr14:15,704,758...15,706,975 		JBrowse link
G Fgf1 fibroblast growth factor 1 involved_in ISS
ISO 		GO_REF:0000024
(PMID:23469107) 		UniProt
RGD		 PMID:23469107 GO_REF:0000024 NCBI chr18:30,686,555...30,772,667
Ensembl chr18:30,686,581...30,772,357 		JBrowse link
G Foxp1 forkhead box P1 involved_in ISO
IEA 		(PMID:24023716)
GO_REF:0000107 		RGD
Ensembl		 PMID:24023716 GO_REF:0000107 NCBI chr 4:131,559,599...132,155,092
Ensembl chr 4:131,564,756...132,112,258 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20543
    developmental process 7160
      anatomical structure morphogenesis 3019
        tissue morphogenesis 717
          morphogenesis of an epithelium 591
            morphogenesis of an endothelium 20
              endothelial tube morphogenesis + 20
Path 2
Term Annotations click to browse term
  biological_process 20543
    developmental process 7160
      anatomical structure development 6656
        tissue development 2325
          tissue morphogenesis 717
            morphogenesis of an epithelium 591
              morphogenesis of an endothelium 20
                endothelial tube morphogenesis + 20
paths to the root