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ONTOLOGY REPORT - ANNOTATIONS

Term:endothelium development
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Accession:GO:0003158 term browser browse the term
Definition:The process whose specific outcome is the progression of an endothelium over time, from its formation to the mature structure. Endothelium refers to the layer of cells lining blood vessels, lymphatics, the heart, and serous cavities, and is derived from bone marrow or mesoderm. Corneal endothelium is a special case, derived from neural crest cells.


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endothelium development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc1 ATP-binding cassette, sub-family C member 1 acts_upstream_of_or_within IMP (PMID:18506003) MGI PMID:18506003 NCBI chr16:14,179,317...14,292,743
Ensembl chr16:14,179,422...14,293,601 		JBrowse link
G Bloc1s6 biogenesis of lysosomal organelles complex-1, subunit 6, pallidin acts_upstream_of_or_within IMP (PMID:12485443) MGI PMID:12485443 NCBI chr 2:122,580,425...122,591,407
Ensembl chr 2:122,580,423...122,591,395 		JBrowse link
G Ccm2 cerebral cavernous malformation 2 involved_in NAS (PMID:17657516) ComplexPortal PMID:17657516 NCBI chr11:6,496,887...6,546,761
Ensembl chr11:6,496,887...6,546,744 		JBrowse link
G Cd2ap CD2-associated protein acts_upstream_of_or_within IMP (PMID:25968128) MGI PMID:25968128 NCBI chr17:43,059,857...43,187,593
Ensembl chr17:43,103,842...43,187,556 		JBrowse link
G Cd34 CD34 antigen involved_in ISO (PMID:17261663) UniProt PMID:17261663 NCBI chr 1:194,621,239...194,643,587
Ensembl chr 1:194,621,127...194,643,587 		JBrowse link
G Cysltr1 cysteinyl leukotriene receptor 1 acts_upstream_of_or_within IMP (PMID:18506003) MGI PMID:18506003 NCBI chr  X:105,617,952...105,647,329
Ensembl chr  X:105,617,952...105,647,285 		JBrowse link
G Gja1 gap junction protein, alpha 1 involved_in ISO
IEA 		RGD
Ensembl		 PMID:10990491 GO_REF:0000107 RGD:7207853 NCBI chr10:56,253,297...56,266,519
Ensembl chr10:56,253,426...56,278,609 		JBrowse link
G Gja4 gap junction protein, alpha 4 involved_in ISO
IEA 		RGD
Ensembl		 PMID:10990491 GO_REF:0000107 RGD:7207853 NCBI chr 4:127,205,213...127,207,832
Ensembl chr 4:127,205,214...127,207,832 		JBrowse link
G Gja5 gap junction protein, alpha 5 ISO RGD PMID:10990491 RGD:7207853 NCBI chr 3:96,939,718...96,960,950
Ensembl chr 3:96,812,009...96,984,732 		JBrowse link
G Kdr kinase insert domain protein receptor involved_in IMP (PMID:7596435) UniProt PMID:7596435 NCBI chr 5:76,093,487...76,139,880
Ensembl chr 5:76,093,487...76,139,118 		JBrowse link
G Krit1 KRIT1, ankyrin repeat containing involved_in NAS (PMID:17657516) ComplexPortal PMID:17657516 NCBI chr 5:3,853,156...3,894,515
Ensembl chr 5:3,853,184...3,895,564 		JBrowse link
G Naglu alpha-N-acetylglucosaminidase (Sanfilippo disease IIIB) acts_upstream_of_or_within IMP (PMID:21408219) MGI PMID:21408219 NCBI chr11:100,960,918...100,968,483
Ensembl chr11:100,960,838...100,968,498 		JBrowse link
G Pdcd10 programmed cell death 10 involved_in NAS (PMID:17657516) ComplexPortal PMID:17657516 NCBI chr 3:75,423,797...75,464,159
Ensembl chr 3:75,423,797...75,464,163 		JBrowse link
G Slc40a1 solute carrier family 40 (iron-regulated transporter), member 1 acts_upstream_of_or_within IMP (PMID:15342464) MGI PMID:15342464 NCBI chr 1:45,947,230...45,965,690
Ensembl chr 1:45,947,228...45,965,683 		JBrowse link
arterial endothelial cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hey1 hairy/enhancer-of-split related with YRPW motif 1 involved_in IGI (PMID:15107403) BHF-UCL PMID:15107403 NCBI chr 3:8,728,419...8,732,098
Ensembl chr 3:8,728,419...8,732,316 		JBrowse link
G Hey2 hairy/enhancer-of-split related with YRPW motif 2 involved_in IGI (PMID:15107403) BHF-UCL PMID:15107403 NCBI chr10:30,708,355...30,718,779
Ensembl chr10:30,708,355...30,718,797 		JBrowse link
G Notch1 notch 1 involved_in IMP (PMID:15107403) BHF-UCL PMID:15107403 NCBI chr 2:26,347,914...26,393,834
Ensembl chr 2:26,347,915...26,406,675 		JBrowse link
G Tmem100 transmembrane protein 100 acts_upstream_of_or_within IMP (PMID:22783020) MGI PMID:22783020 NCBI chr11:89,921,174...89,927,334
Ensembl chr11:89,921,174...89,927,334 		JBrowse link
arterial endothelial cell fate commitment term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rbpj recombination signal binding protein for immunoglobulin kappa J region involved_in IMP (PMID:15466160) BHF-UCL PMID:15466160 NCBI chr 5:53,713,121...53,814,787
Ensembl chr 5:53,623,494...53,814,704 		JBrowse link
blood vessel endothelial cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccm2 cerebral cavernous malformation 2 acts_upstream_of_or_within IMP (PMID:19151727) MGI PMID:19151727 NCBI chr11:6,496,887...6,546,761
Ensembl chr11:6,496,887...6,546,744 		JBrowse link
G Hey1 hairy/enhancer-of-split related with YRPW motif 1 acts_upstream_of_or_within IGI (PMID:15107403) MGI PMID:15107403 NCBI chr 3:8,728,419...8,732,098
Ensembl chr 3:8,728,419...8,732,316 		JBrowse link
G Hey2 hairy/enhancer-of-split related with YRPW motif 2 acts_upstream_of_or_within IGI (PMID:15107403) MGI PMID:15107403 NCBI chr10:30,708,355...30,718,779
Ensembl chr10:30,708,355...30,718,797 		JBrowse link
G Kdr kinase insert domain protein receptor acts_upstream_of_or_within
involved_in 		IMP
TAS 		(PMID:15644447)
(PMID:20406889) 		MGI
DFLAT		 PMID:15644447 PMID:20406889 NCBI chr 5:76,093,487...76,139,880
Ensembl chr 5:76,093,487...76,139,118 		JBrowse link
G Lipa lysosomal acid lipase A acts_upstream_of_or_within IMP (PMID:33357458) MGI PMID:33357458 NCBI chr19:34,469,716...34,504,874
Ensembl chr19:34,469,718...34,504,874 		JBrowse link
G Prox1 prospero homeobox 1 acts_upstream_of_or_within IMP (PMID:11927535) MGI PMID:11927535 NCBI chr 1:189,850,232...189,903,024
Ensembl chr 1:189,850,232...189,902,911 		JBrowse link
blood vessel endothelial cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rbpj recombination signal binding protein for immunoglobulin kappa J region involved_in IGI (PMID:15466160) BHF-UCL PMID:15466160 NCBI chr 5:53,713,121...53,814,787
Ensembl chr 5:53,623,494...53,814,704 		JBrowse link
blood vessel lumenization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dll4 delta like canonical Notch ligand 4 involved_in IMP (PMID:15466160) BHF-UCL PMID:15466160 NCBI chr 2:119,156,286...119,166,145
Ensembl chr 2:119,156,265...119,166,443 		JBrowse link
G Rbpj recombination signal binding protein for immunoglobulin kappa J region involved_in IMP (PMID:15466160) BHF-UCL PMID:15466160 NCBI chr 5:53,713,121...53,814,787
Ensembl chr 5:53,623,494...53,814,704 		JBrowse link
endocardial cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Notch1 notch 1 involved_in IMP (PMID:20890042) BHF-UCL PMID:20890042 NCBI chr 2:26,347,914...26,393,834
Ensembl chr 2:26,347,915...26,406,675 		JBrowse link
G Nrg1 neuregulin 1 involved_in ISO GO_Central GO_REF:0000119 NCBI chr 8:32,299,493...33,381,858
Ensembl chr 8:32,304,579...33,374,825
Ensembl chr 8:32,304,579...33,374,825 		JBrowse link
G Smad4 SMAD family member 4 involved_in IMP (PMID:21330551) BHF-UCL PMID:21330551 NCBI chr18:73,767,861...73,836,862
Ensembl chr18:73,772,080...73,836,851 		JBrowse link
G Sox17 SRY (sex determining region Y)-box 17 acts_upstream_of_or_within IGI (PMID:17610846) MGI PMID:17610846 NCBI chr 1:4,561,154...4,567,624
Ensembl chr 1:4,561,154...4,567,577 		JBrowse link
G Sox18 SRY (sex determining region Y)-box 18 acts_upstream_of_or_within IGI (PMID:17610846) MGI PMID:17610846 NCBI chr 2:181,311,630...181,313,433
Ensembl chr 2:181,311,629...181,313,433 		JBrowse link
endocardial cushion cell fate commitment term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acvr1 activin A receptor, type 1 involved_in ISO
IEA 		GO_Central
Ensembl		 GO_REF:0000107 GO_REF:0000119 NCBI chr 2:58,336,450...58,456,840
Ensembl chr 2:58,278,656...58,457,169 		JBrowse link
endothelial cell development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccm2 cerebral cavernous malformation 2 acts_upstream_of_or_within IGI
IMP 		(PMID:19151727) MGI PMID:19151727 NCBI chr11:6,496,887...6,546,761
Ensembl chr11:6,496,887...6,546,744 		JBrowse link
G Gpx1 glutathione peroxidase 1 acts_upstream_of_or_within IMP (PMID:16373599) MGI PMID:16373599 NCBI chr 9:108,216,279...108,217,541
Ensembl chr 9:108,216,102...108,217,542 		JBrowse link
G Heg1 heart development protein with EGF-like domains 1 acts_upstream_of_or_within IGI (PMID:19151727) MGI PMID:19151727 NCBI chr16:33,504,754...33,591,946
Ensembl chr16:33,504,740...33,591,946 		JBrowse link
G Ubiad1 UbiA prenyltransferase domain containing 1 involved_in ISS UniProt GO_REF:0000024 NCBI chr 4:148,518,952...148,529,217
Ensembl chr 4:148,518,952...148,529,228 		JBrowse link
G Vezf1 vascular endothelial zinc finger 1 acts_upstream_of_or_within IMP (PMID:15882861) MGI PMID:15882861 NCBI chr11:87,959,084...87,975,555
Ensembl chr11:87,959,105...87,975,555 		JBrowse link
endothelial cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Barx1 BarH-like homeobox 1 acts_upstream_of_or_within IMP (PMID:15809042) MGI PMID:15809042 NCBI chr13:48,816,512...48,819,983
Ensembl chr13:48,816,474...48,819,983 		JBrowse link
G Cxcr4 C-X-C motif chemokine receptor 4 involved_in ISO RGD
GO_Central		 PMID:24955809 GO_REF:0000096 RGD:11352686 NCBI chr 1:128,515,936...128,520,036
Ensembl chr 1:128,515,936...128,520,030 		JBrowse link
G Fstl1 follistatin-like 1 involved_in IMP (PMID:20054002) UniProt PMID:20054002 NCBI chr16:37,597,417...37,656,878
Ensembl chr16:37,597,235...37,656,876 		JBrowse link
G Fzd1 frizzled class receptor 1 acts_upstream_of_or_within IGI
IDA 		(PMID:15809042) MGI PMID:15809042 NCBI chr 5:4,803,839...4,808,216
Ensembl chr 5:4,803,839...4,808,035 		JBrowse link
G Fzd2 frizzled class receptor 2 acts_upstream_of_or_within IGI
IDA 		(PMID:15809042) MGI PMID:15809042 NCBI chr11:102,495,257...102,498,884
Ensembl chr11:102,495,222...102,498,884 		JBrowse link
G Fzd4 frizzled class receptor 4 acts_upstream_of_or_within IMP (PMID:23217714) MGI PMID:23217714 NCBI chr 7:89,053,574...89,062,341
Ensembl chr 7:89,053,563...89,062,342 		JBrowse link
G Hoxb5 homeobox B5 acts_upstream_of_or_within IDA (PMID:12897140) MGI PMID:12897140 NCBI chr11:96,194,338...96,196,947
Ensembl chr11:96,194,162...96,196,947 		JBrowse link
G Kdm6b KDM1 lysine (K)-specific demethylase 6B involved_in IMP (PMID:23856522) BHF-UCL PMID:23856522 NCBI chr11:69,289,334...69,311,188
Ensembl chr11:69,289,334...69,304,501 		JBrowse link
G Kdr kinase insert domain protein receptor involved_in
acts_upstream_of_or_within 		IBA
TAS
IMP
IDA 		(PMID:20406889)
(PMID:18772315)
(PMID:12897140) 		GO_Central
DFLAT
MGI		 PMID:12897140 PMID:18772315 PMID:20406889 GO_REF:0000033 NCBI chr 5:76,093,487...76,139,880
Ensembl chr 5:76,093,487...76,139,118 		JBrowse link
G Mesp1 mesoderm posterior 1 involved_in IEA
ISO 		Ensembl
GO_Central		 GO_REF:0000107 GO_REF:0000119 NCBI chr 7:79,441,989...79,443,338
Ensembl chr 7:79,441,989...79,443,536 		JBrowse link
G Ndp Norrie disease (pseudoglioma) (human) acts_upstream_of_or_within IMP (PMID:23217714) MGI PMID:23217714 NCBI chr  X:16,751,760...16,778,013
Ensembl chr  X:16,751,760...16,778,013 		JBrowse link
G Notch4 notch 4 involved_in ISO RGD
GO_Central		 PMID:10964583 GO_REF:0000096 RGD:1304484 NCBI chr17:34,783,257...34,807,517
Ensembl chr17:34,783,242...34,807,477 		JBrowse link
G Ptn pleiotrophin ISO RGD PMID:20830586 RGD:9686141 NCBI chr 6:36,691,863...36,787,114
Ensembl chr 6:36,691,864...36,787,155 		JBrowse link
G S1pr1 sphingosine-1-phosphate receptor 1 involved_in ISO
IEA 		RGD
Ensembl		 PMID:7959012 GO_REF:0000107 RGD:61573 NCBI chr 3:115,504,082...115,508,704
Ensembl chr 3:115,504,082...115,508,721 		JBrowse link
G Vhl von Hippel-Lindau tumor suppressor acts_upstream_of IMP (PMID:25186293) MGI PMID:25186293 NCBI chr 6:113,600,955...113,608,595
Ensembl chr 6:113,600,920...113,608,594 		JBrowse link
endothelial cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hoxa13 homeobox A13 acts_upstream_of_or_within IMP (PMID:18483557) MGI PMID:18483557 NCBI chr 6:52,235,833...52,237,865
Ensembl chr 6:52,234,674...52,237,788 		JBrowse link
endothelial cell morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Amotl2 angiomotin-like 2 involved_in IMP (PMID:24806444) UniProt PMID:24806444 NCBI chr 9:102,594,290...102,610,616
Ensembl chr 9:102,593,871...102,610,617 		JBrowse link
G Arhgef26 Rho guanine nucleotide exchange factor 26 acts_upstream_of_or_within IMP (PMID:23372835) MGI PMID:23372835 NCBI chr 3:62,244,946...62,369,642
Ensembl chr 3:62,245,765...62,369,642 		JBrowse link
G Cdh5 cadherin 5 involved_in IMP (PMID:24806444) UniProt PMID:24806444 NCBI chr 8:104,828,247...104,871,136
Ensembl chr 8:104,828,257...104,871,143 		JBrowse link
G Clic4 chloride intracellular channel 4 acts_upstream_of_or_within IMP (PMID:19197003) MGI PMID:19197003 NCBI chr 4:134,941,280...135,000,071
Ensembl chr 4:134,941,280...135,000,125 		JBrowse link
G Cnmd chondromodulin acts_upstream_of_or_within IDA (PMID:12714610) MGI PMID:12714610 NCBI chr14:79,875,126...79,899,596
Ensembl chr14:79,875,130...79,899,610 		JBrowse link
G Col18a1 collagen, type XVIII, alpha 1 involved_in
acts_upstream_of_or_within 		IBA
IDA 		(PMID:15188432) GO_Central
MGI		 PMID:15188432 GO_REF:0000033 NCBI chr10:76,888,013...77,002,351
Ensembl chr10:76,888,012...77,002,382 		JBrowse link
G Heg1 heart development protein with EGF-like domains 1 acts_upstream_of_or_within IMP (PMID:19151727) MGI PMID:19151727 NCBI chr16:33,504,754...33,591,946
Ensembl chr16:33,504,740...33,591,946 		JBrowse link
G Hoxa13 homeobox A13 acts_upstream_of_or_within IMP (PMID:18483557) MGI PMID:18483557 NCBI chr 6:52,235,833...52,237,865
Ensembl chr 6:52,234,674...52,237,788 		JBrowse link
G Id1 inhibitor of DNA binding 1, HLH protein acts_upstream_of_or_within IMP (PMID:17717145) MGI PMID:17717145 NCBI chr 2:152,578,171...152,579,330
Ensembl chr 2:152,578,171...152,579,330 		JBrowse link
G Ift88 intraflagellar transport 88 acts_upstream_of_or_within IMP (PMID:21285373) MGI PMID:21285373 NCBI chr14:57,661,519...57,755,393
Ensembl chr14:57,661,519...57,755,393 		JBrowse link
G Magi1 membrane associated guanylate kinase, WW and PDZ domain containing 1 involved_in IMP (PMID:24806444) UniProt PMID:24806444 NCBI chr 6:93,652,434...94,260,906
Ensembl chr 6:93,652,436...94,260,898 		JBrowse link
G Met met proto-oncogene involved_in ISO GO_Central GO_REF:0000119 NCBI chr 6:17,463,351...17,573,979
Ensembl chr 6:17,463,799...17,573,979 		JBrowse link
G Notch4 notch 4 involved_in ISO RGD
GO_Central		 PMID:10964583 GO_REF:0000096 RGD:1304484 NCBI chr17:34,783,257...34,807,517
Ensembl chr17:34,783,242...34,807,477 		JBrowse link
G Pecam1 platelet/endothelial cell adhesion molecule 1 acts_upstream_of_or_within IMP (PMID:17563397) MGI PMID:17563397 NCBI chr11:106,545,039...106,606,107
Ensembl chr11:106,545,043...106,641,454 		JBrowse link
G Plod3 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3 acts_upstream_of_or_within IMP (PMID:16467571) MGI PMID:16467571 NCBI chr 5:137,015,873...137,025,500
Ensembl chr 5:137,015,873...137,025,502 		JBrowse link
G Stc1 stanniocalcin 1 involved_in ISO
IEA 		GO_Central
Ensembl		 GO_REF:0000107 GO_REF:0000119 NCBI chr14:69,266,738...69,278,850
Ensembl chr14:69,266,687...69,279,253 		JBrowse link
G Tnmd tenomodulin acts_upstream_of_or_within IDA (PMID:12714610) MGI PMID:12714610 NCBI chr  X:132,751,757...132,766,326
Ensembl chr  X:132,751,729...132,766,326 		JBrowse link
endothelial tip cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dll1 delta like canonical Notch ligand 1 involved_in IMP (PMID:22282195) UniProt PMID:22282195 NCBI chr17:15,587,616...15,597,275
Ensembl chr17:15,587,616...15,597,134 		JBrowse link
G Flvcr2 feline leukemia virus subgroup C cellular receptor 2 acts_upstream_of_or_within IMP (PMID:32369453) MGI PMID:32369453 NCBI chr12:85,793,313...85,860,359
Ensembl chr12:85,793,313...85,860,359 		JBrowse link
endothelial tube lumen extension term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rhoa ras homolog family member A acts_upstream_of_or_within ISO (PMID:20208559) MGI PMID:20208559 NCBI chr 9:108,183,359...108,215,142
Ensembl chr 9:108,183,328...108,215,133 		JBrowse link
G Stard13 StAR related lipid transfer domain containing 13 acts_upstream_of_or_within ISO (PMID:20208559) MGI PMID:20208559 NCBI chr 5:150,960,975...151,351,780
Ensembl chr 5:150,960,975...151,157,301 		JBrowse link
endothelial tube morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acvrl1 activin A receptor, type II-like 1 involved_in IEA
ISO 		Ensembl
GO_Central		 GO_REF:0000107 GO_REF:0000119 NCBI chr15:101,026,403...101,043,217
Ensembl chr15:101,026,403...101,043,217 		JBrowse link
G Bsg basigin involved_in ISS
ISO 		UniProt
GO_Central		 GO_REF:0000024 GO_REF:0000119 NCBI chr10:79,540,192...79,547,813
Ensembl chr10:79,540,325...79,547,803 		JBrowse link
G Ccm2 cerebral cavernous malformation 2 acts_upstream_of_or_within ISO (PMID:19151727) MGI PMID:19151727 NCBI chr11:6,496,887...6,546,761
Ensembl chr11:6,496,887...6,546,744 		JBrowse link
G Csnk2b casein kinase 2, beta polypeptide involved_in ISO GO_Central GO_REF:0000119 NCBI chr17:35,335,171...35,341,029
Ensembl chr17:35,335,172...35,341,029 		JBrowse link
G Ctnnb1 catenin beta 1 involved_in ISO
ISS 		GO_Central
UniProt		 GO_REF:0000024 GO_REF:0000119 NCBI chr 9:120,762,466...120,789,573
Ensembl chr 9:120,758,282...120,789,573 		JBrowse link
G Cxcr4 C-X-C motif chemokine receptor 4 involved_in ISO RGD
GO_Central		 PMID:24955809 GO_REF:0000096 RGD:11352686 NCBI chr 1:128,515,936...128,520,036
Ensembl chr 1:128,515,936...128,520,030 		JBrowse link
G Kdr kinase insert domain protein receptor involved_in ISO RGD
GO_Central		 PMID:25942475 GO_REF:0000096 RGD:126925211 NCBI chr 5:76,093,487...76,139,880
Ensembl chr 5:76,093,487...76,139,118 		JBrowse link
G Mir21a microRNA 21a involved_in ISO (PMID:21347332) BHF-UCL PMID:21347332 NCBI chr11:86,474,893...86,474,984
Ensembl chr11:86,474,893...86,474,984 		JBrowse link
G Rhob ras homolog family member B involved_in ISO
IEA 		GO_Central
Ensembl		 GO_REF:0000107 GO_REF:0000119 NCBI chr12:8,547,661...8,550,009
Ensembl chr12:8,547,661...8,550,009 		JBrowse link
epicardium-derived cardiac endothelial cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pbrm1 polybromo 1 involved_in TAS (PMID:20299672) DFLAT PMID:20299672 NCBI chr14:30,741,095...30,843,549
Ensembl chr14:30,741,095...30,843,549 		JBrowse link
G Prok2 prokineticin 2 involved_in TAS (PMID:20299672) DFLAT PMID:20299672 NCBI chr 6:99,687,833...99,703,368
Ensembl chr 6:99,688,260...99,703,353 		JBrowse link
establishment of blood-nerve barrier term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agt angiotensinogen acts_upstream_of_or_within IMP (PMID:9734405) MGI PMID:9734405 NCBI chr 8:125,283,326...125,296,445
Ensembl chr 8:125,283,273...125,296,445 		JBrowse link
G Cldn1 claudin 1 involved_in ISO
IEA 		RGD
GO_Central
Ensembl		 PMID:22733753 GO_REF:0000096 GO_REF:0000107 RGD:11341802 NCBI chr16:26,175,395...26,190,589
Ensembl chr16:26,175,392...26,190,591 		JBrowse link
G Dmd dystrophin, muscular dystrophy acts_upstream_of_or_within IMP (PMID:12673830) MGI PMID:12673830 NCBI chr  X:81,858,244...84,248,656
Ensembl chr  X:81,992,476...84,249,747 		JBrowse link
G Hapln2 hyaluronan and proteoglycan link protein 2 acts_upstream_of_or_within IMP (PMID:20181608) MGI PMID:20181608 NCBI chr 3:87,927,865...87,934,818
Ensembl chr 3:87,929,057...87,934,890 		JBrowse link
G Ren1 renin 1 structural NOT|acts_upstream_of_or_within IMP (PMID:10617578) MGI PMID:10617578 NCBI chr 1:133,278,412...133,288,058
Ensembl chr 1:133,278,248...133,288,063 		JBrowse link
establishment of endothelial barrier term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cldn5 claudin 5 involved_in ISO (PMID:24280217) AgBase PMID:24280217 NCBI chr16:18,595,597...18,597,012
Ensembl chr16:18,595,597...18,597,012 		JBrowse link
G Edn1 endothelin 1 acts_upstream_of_or_within IDA (PMID:27026367) MGI PMID:27026367 NCBI chr13:42,454,952...42,461,466
Ensembl chr13:42,454,952...42,461,466 		JBrowse link
G Ednra endothelin receptor type A involved_in IDA (PMID:27026367) MGI PMID:27026367 NCBI chr 8:78,389,658...78,451,081
Ensembl chr 8:78,389,660...78,451,093 		JBrowse link
G Ednrb endothelin receptor type B involved_in IDA (PMID:27026367) MGI PMID:27026367 NCBI chr14:104,052,055...104,081,764
Ensembl chr14:104,052,061...104,081,838 		JBrowse link
G Ezr ezrin involved_in IEA
ISO 		Ensembl
GO_Central		 GO_REF:0000107 GO_REF:0000119 NCBI chr17:7,005,530...7,050,179
Ensembl chr17:7,005,440...7,050,183 		JBrowse link
G F2rl1 F2R like trypsin receptor 1 involved_in ISO
IEA 		GO_Central
Ensembl		 GO_REF:0000107 GO_REF:0000119 NCBI chr13:95,648,226...95,661,748
Ensembl chr13:95,648,240...95,661,735 		JBrowse link
G Hpse heparanase involved_in IDA (PMID:27026367) MGI PMID:27026367 NCBI chr 5:100,827,350...100,867,582
Ensembl chr 5:100,827,350...100,867,582 		JBrowse link
G Icam1 intercellular adhesion molecule 1 involved_in ISO
IEA 		GO_Central
Ensembl		 GO_REF:0000107 GO_REF:0000119 NCBI chr 9:20,927,236...20,940,110
Ensembl chr 9:20,927,281...20,940,113 		JBrowse link
G Marveld2 MARVEL (membrane-associating) domain containing 2 involved_in IEA
ISO 		Ensembl
GO_Central		 GO_REF:0000107 GO_REF:0000119 NCBI chr13:100,732,465...100,753,479
Ensembl chr13:100,732,465...100,753,479 		JBrowse link
G Msn moesin involved_in ISO
IEA 		GO_Central
Ensembl		 GO_REF:0000107 GO_REF:0000119 NCBI chr  X:95,139,651...95,212,159
Ensembl chr  X:95,139,648...95,212,158 		JBrowse link
G Myadm myeloid-associated differentiation marker involved_in IEA
ISO 		Ensembl
GO_Central		 GO_REF:0000107 GO_REF:0000119 NCBI chr 7:3,337,563...3,347,871
Ensembl chr 7:3,337,605...3,348,958 		JBrowse link
G Pde2a phosphodiesterase 2A, cGMP-stimulated involved_in ISS
ISO 		UniProt
GO_Central		 GO_REF:0000024 GO_REF:0000096 NCBI chr 7:101,070,905...101,162,026
Ensembl chr 7:101,060,093...101,162,026
Ensembl chr 7:101,060,093...101,162,026 		JBrowse link
G Pde4d phosphodiesterase 4D, cAMP specific involved_in ISS
ISO 		UniProt
GO_Central		 GO_REF:0000024 GO_REF:0000096 NCBI chr13:108,790,711...110,092,503
Ensembl chr13:108,586,482...110,089,995 		JBrowse link
G Pecam1 platelet/endothelial cell adhesion molecule 1 involved_in ISO GO_Central GO_REF:0000119 NCBI chr11:106,545,039...106,606,107
Ensembl chr11:106,545,043...106,641,454 		JBrowse link
G Ppp1r16b protein phosphatase 1, regulatory subunit 16B acts_upstream_of_or_within
involved_in 		IMP
IBA 		(PMID:21907835) MGI
GO_Central		 PMID:21907835 GO_REF:0000033 NCBI chr 2:158,508,653...158,608,254
Ensembl chr 2:158,507,318...158,608,254 		JBrowse link
G Rap1a RAS-related protein 1a involved_in ISS
ISO 		UniProt
GO_Central		 GO_REF:0000024 GO_REF:0000119 NCBI chr 3:105,634,576...105,708,740
Ensembl chr 3:105,634,583...105,708,652 		JBrowse link
G Rap1b RAS related protein 1b involved_in ISS UniProt GO_REF:0000024 NCBI chr10:117,650,502...117,681,879
Ensembl chr10:117,649,776...117,681,940 		JBrowse link
G Rapgef1 Rap guanine nucleotide exchange factor (GEF) 1 involved_in ISO GO_Central GO_REF:0000119 NCBI chr 2:29,509,732...29,630,376
Ensembl chr 2:29,509,732...29,630,990 		JBrowse link
G Rapgef2 Rap guanine nucleotide exchange factor (GEF) 2 involved_in ISO
ISS 		GO_Central
UniProt		 GO_REF:0000024 GO_REF:0000119 NCBI chr 3:78,969,818...79,194,681
Ensembl chr 3:78,969,823...79,193,824 		JBrowse link
G Rapgef3 Rap guanine nucleotide exchange factor (GEF) 3 involved_in ISO
ISS 		GO_Central
UniProt		 GO_REF:0000024 GO_REF:0000119 NCBI chr15:97,637,886...97,666,300
Ensembl chr15:97,642,651...97,665,853 		JBrowse link
G Rdx radixin involved_in ISO GO_Central GO_REF:0000119 NCBI chr 9:51,958,450...52,000,038
Ensembl chr 9:51,958,473...52,011,763 		JBrowse link
G Robo4 roundabout guidance receptor 4 involved_in ISO GO_Central GO_REF:0000119 NCBI chr 9:37,313,198...37,325,319
Ensembl chr 9:37,313,193...37,326,411 		JBrowse link
G Sox18 SRY (sex determining region Y)-box 18 involved_in IEA
ISO 		Ensembl
GO_Central		 GO_REF:0000107 GO_REF:0000119 NCBI chr 2:181,311,630...181,313,433
Ensembl chr 2:181,311,629...181,313,433 		JBrowse link
establishment of endothelial blood-brain barrier term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1b ATP-binding cassette, sub-family B member 1B involved_in ISO RGD
GO_Central		 PMID:16850390 GO_REF:0000096 RGD:1598561 NCBI chr 5:8,848,147...8,916,314
Ensembl chr 5:8,848,147...8,916,315 		JBrowse link
G Cldn3 claudin 3 involved_in IMP (PMID:12734665) ARUK-UCL PMID:12734665 NCBI chr 5:135,015,068...135,016,330
Ensembl chr 5:135,015,068...135,016,326 		JBrowse link
G Foxp3 forkhead box P3 involved_in ISO
IEA 		RGD
Ensembl		 PMID:31027862 GO_REF:0000107 RGD:38549575 NCBI chr  X:7,445,915...7,461,482
Ensembl chr  X:7,439,883...7,461,484 		JBrowse link
establishment of endothelial intestinal barrier term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Afdn afadin, adherens junction formation factor involved_in ISO GO_Central GO_REF:0000119 NCBI chr17:13,980,735...14,126,059
Ensembl chr17:13,980,801...14,126,412 		JBrowse link
G Cldn1 claudin 1 involved_in ISO
IEA 		RGD
Ensembl
GO_Central		 PMID:22684624 GO_REF:0000096 GO_REF:0000107 RGD:11341733 NCBI chr16:26,175,395...26,190,589
Ensembl chr16:26,175,392...26,190,591 		JBrowse link
G F11r F11 receptor involved_in IBA
ISO
IEA 		GO_Central
Ensembl		 GO_REF:0000033 GO_REF:0000107 GO_REF:0000119 NCBI chr 1:171,265,129...171,292,161
Ensembl chr 1:171,265,103...171,292,171 		JBrowse link
G Fasn fatty acid synthase acts_upstream_of_or_within IMP (PMID:25565205) MGI PMID:25565205 NCBI chr11:120,696,784...120,715,992
Ensembl chr11:120,696,672...120,715,373 		JBrowse link
G Icam1 intercellular adhesion molecule 1 involved_in ISO RGD
GO_Central		 PMID:10201790 GO_REF:0000096 RGD:11520782 NCBI chr 9:20,927,236...20,940,110
Ensembl chr 9:20,927,281...20,940,113 		JBrowse link
G Mir874 microRNA 874 acts_upstream_of_or_within IDA (PMID:24462679) MGI PMID:24462679 NCBI chr13:58,170,939...58,171,014
Ensembl chr13:58,170,939...58,171,014 		JBrowse link
G Myd88 myeloid differentiation primary response gene 88 acts_upstream_of_or_within IMP (PMID:22155109) MGI PMID:22155109 NCBI chr 9:119,165,000...119,169,084
Ensembl chr 9:119,165,000...119,170,477 		JBrowse link
G Ptprs protein tyrosine phosphatase receptor type S acts_upstream_of_or_within IMP (PMID:24385580) MGI PMID:24385580 NCBI chr17:56,719,426...56,783,480
Ensembl chr17:56,719,426...56,783,483 		JBrowse link
G Rab1a RAB1A, member RAS oncogene family NOT|involved_in ISO (PMID:23885123) UniProt PMID:23885123 NCBI chr11:20,151,412...20,176,856
Ensembl chr11:20,151,432...20,176,856 		JBrowse link
G Rab1b RAB1B, member RAS oncogene family NOT|involved_in ISO (PMID:23885123) UniProt PMID:23885123 NCBI chr19:5,149,235...5,157,024
Ensembl chr19:5,149,233...5,157,100 		JBrowse link
G Rap2b RAP2B, member of RAS oncogene family NOT|involved_in ISO (PMID:23885123) UniProt PMID:23885123 NCBI chr 3:61,271,928...61,276,124
Ensembl chr 3:61,269,059...61,275,851 		JBrowse link
G Rap2c RAP2C, member of RAS oncogene family involved_in IEA
ISO 		Ensembl
GO_Central		 GO_REF:0000107 GO_REF:0000119 NCBI chr  X:50,093,163...50,108,966
Ensembl chr  X:50,092,789...50,106,895 		JBrowse link
G Rapgef2 Rap guanine nucleotide exchange factor (GEF) 2 involved_in ISO GO_Central GO_REF:0000119 NCBI chr 3:78,969,818...79,194,681
Ensembl chr 3:78,969,823...79,193,824 		JBrowse link
G Rapgef6 Rap guanine nucleotide exchange factor (GEF) 6 NOT|involved_in ISO (PMID:23885123) UniProt PMID:23885123 NCBI chr11:54,413,630...54,590,112
Ensembl chr11:54,413,673...54,590,111 		JBrowse link
G Tjp1 tight junction protein 1 involved_in ISO
IBA 		GO_Central GO_REF:0000033 GO_REF:0000119 NCBI chr 7:64,945,913...65,177,629
Ensembl chr 7:64,945,913...65,177,529 		JBrowse link
G Tjp2 tight junction protein 2 involved_in ISO
IBA 		GO_Central GO_REF:0000033 GO_REF:0000119 NCBI chr19:24,071,860...24,202,492
Ensembl chr19:24,071,869...24,202,394 		JBrowse link
G Tjp3 tight junction protein 3 involved_in IBA GO_Central GO_REF:0000033 NCBI chr10:81,109,022...81,127,415
Ensembl chr10:81,109,041...81,127,415 		JBrowse link
glomerular endothelium development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd34 CD34 antigen involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:194,621,239...194,643,587
Ensembl chr 1:194,621,127...194,643,587 		JBrowse link
G Edn1 endothelin 1 involved_in IDA (PMID:31402170) MGI PMID:31402170 NCBI chr13:42,454,952...42,461,466
Ensembl chr13:42,454,952...42,461,466 		JBrowse link
G Ednra endothelin receptor type A involved_in IDA (PMID:31402170) MGI PMID:31402170 NCBI chr 8:78,389,658...78,451,081
Ensembl chr 8:78,389,660...78,451,093 		JBrowse link
G Foxc2 forkhead box C2 acts_upstream_of_or_within IMP (PMID:16498405) MGI PMID:16498405 NCBI chr 8:121,842,910...121,845,634
Ensembl chr 8:121,842,910...121,845,634 		JBrowse link
G Pecam1 platelet/endothelial cell adhesion molecule 1 involved_in ISO (PMID:17464107) UniProt PMID:17464107 NCBI chr11:106,545,039...106,606,107
Ensembl chr11:106,545,043...106,641,454 		JBrowse link
lymphatic endothelial cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acvr2b activin receptor IIB involved_in IMP (PMID:19903896) BHF-UCL PMID:19903896 NCBI chr 9:119,231,081...119,271,214
Ensembl chr 9:119,231,184...119,264,061 		JBrowse link
G Acvrl1 activin A receptor, type II-like 1 involved_in IMP
ISO 		(PMID:19903896) BHF-UCL
GO_Central		 PMID:19903896 GO_REF:0000119 NCBI chr15:101,026,403...101,043,217
Ensembl chr15:101,026,403...101,043,217 		JBrowse link
G Bmpr2 bone morphogenetic protein receptor type 2 involved_in IMP (PMID:19903896) BHF-UCL PMID:19903896 NCBI chr 1:59,802,721...59,917,240
Ensembl chr 1:59,802,559...59,918,173 		JBrowse link
G Prox1 prospero homeobox 1 acts_upstream_of_or_within
involved_in 		IMP
ISO 		(PMID:19056883) MGI
GO_Central		 PMID:19056883 GO_REF:0000119 NCBI chr 1:189,850,232...189,903,024
Ensembl chr 1:189,850,232...189,902,911 		JBrowse link
G Sox18 SRY (sex determining region Y)-box 18 acts_upstream_of_or_within IMP (PMID:18931657) MGI PMID:18931657 NCBI chr 2:181,311,630...181,313,433
Ensembl chr 2:181,311,629...181,313,433 		JBrowse link
G Tie1 tyrosine kinase with immunoglobulin-like and EGF-like domains 1 acts_upstream_of_or_within IMP (PMID:20223757) BHF-UCL PMID:20223757 NCBI chr 4:118,328,388...118,347,046
Ensembl chr 4:118,328,388...118,347,258 		JBrowse link
lymphatic endothelial cell fate commitment term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nr2f2 nuclear receptor subfamily 2, group F, member 2 involved_in IEA
ISO 		Ensembl
GO_Central		 GO_REF:0000107 GO_REF:0000119 NCBI chr 7:70,001,694...70,016,494
Ensembl chr 7:70,001,692...70,016,483 		JBrowse link
G Pdpn podoplanin involved_in IMP (PMID:20110424) UniProt PMID:20110424 NCBI chr 4:142,993,979...143,026,134
Ensembl chr 4:142,994,001...143,026,134 		JBrowse link
G Prox1 prospero homeobox 1 involved_in IEA
ISO 		Ensembl
GO_Central		 GO_REF:0000107 GO_REF:0000119 NCBI chr 1:189,850,232...189,903,024
Ensembl chr 1:189,850,232...189,902,911 		JBrowse link
metanephric glomerular endothelium development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pdgfb platelet derived growth factor, B polypeptide involved_in IEP (PMID:9693135) UniProt PMID:9693135 NCBI chr15:79,880,066...79,899,178
Ensembl chr15:79,880,075...79,899,178 		JBrowse link
negative regulation of blood vessel endothelial cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Foxj2 forkhead box J2 involved_in ISO
IEA 		GO_Central
Ensembl		 GO_REF:0000107 GO_REF:0000119 NCBI chr 6:122,797,143...122,822,325
Ensembl chr 6:122,796,873...122,822,325 		JBrowse link
negative regulation of endothelial cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acvrl1 activin A receptor, type II-like 1 involved_in IDA (PMID:20406889) DFLAT PMID:20406889 NCBI chr15:101,026,403...101,043,217
Ensembl chr15:101,026,403...101,043,217 		JBrowse link
G Dsg2 desmoglein 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:20,691,247...20,737,583
Ensembl chr18:20,691,131...20,737,578 		JBrowse link
G Id1 inhibitor of DNA binding 1, HLH protein involved_in ISO RGD
GO_Central		 PMID:20830586 GO_REF:0000096 RGD:9686141 NCBI chr 2:152,578,171...152,579,330
Ensembl chr 2:152,578,171...152,579,330 		JBrowse link
G Jag1 jagged 1 involved_in IDA (PMID:25535084) BHF-UCL PMID:25535084 NCBI chr 2:136,923,371...136,958,440
Ensembl chr 2:136,923,376...136,958,564 		JBrowse link
G Mir1a-1 microRNA 1a-1 involved_in ISO (PMID:23939491) BHF-UCL PMID:23939491 NCBI chr 2:180,030,841...180,030,917
Ensembl chr 2:180,030,841...180,030,917 		JBrowse link
G Mir1a-2 microRNA 1a-2 involved_in ISO (PMID:23939491) BHF-UCL PMID:23939491 NCBI chr18:10,785,481...10,785,552
Ensembl chr18:10,785,481...10,785,552 		JBrowse link
G Mir495 microRNA 495 involved_in ISO (PMID:27538588) BHF-UCL PMID:27538588 NCBI chr12:109,685,188...109,685,250
Ensembl chr12:109,685,188...109,685,250 		JBrowse link
G Notch4 notch 4 involved_in IMP (PMID:11344305) UniProt PMID:11344305 NCBI chr17:34,783,257...34,807,517
Ensembl chr17:34,783,242...34,807,477 		JBrowse link
G Tgfbr1 transforming growth factor, beta receptor I involved_in ISO RGD
GO_Central		 PMID:17450384 GO_REF:0000096 RGD:2302022 NCBI chr 4:47,353,258...47,414,926
Ensembl chr 4:47,353,222...47,414,931 		JBrowse link
G Vhl von Hippel-Lindau tumor suppressor acts_upstream_of_or_within IMP (PMID:25186293) MGI PMID:25186293 NCBI chr 6:113,600,955...113,608,595
Ensembl chr 6:113,600,920...113,608,594 		JBrowse link
G Xdh xanthine dehydrogenase involved_in ISO GO_Central GO_REF:0000119 NCBI chr17:74,190,890...74,257,191
Ensembl chr17:74,190,890...74,257,191 		JBrowse link
G Zeb1 zinc finger E-box binding homeobox 1 involved_in IEA
ISO 		Ensembl
GO_Central		 GO_REF:0000107 GO_REF:0000119 NCBI chr18:5,591,330...5,775,468
Ensembl chr18:5,591,860...5,775,467 		JBrowse link
negative regulation of establishment of endothelial barrier term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G S1pr3 sphingosine-1-phosphate receptor 3 involved_in IEA
ISO 		Ensembl
GO_Central		 GO_REF:0000107 GO_REF:0000119 NCBI chr13:51,562,654...51,576,833
Ensembl chr13:51,562,675...51,576,833 		JBrowse link
G Vegfa vascular endothelial growth factor A involved_in IEA
ISO 		Ensembl
GO_Central		 GO_REF:0000107 GO_REF:0000119 NCBI chr17:46,327,919...46,343,303
Ensembl chr17:46,327,919...46,343,295 		JBrowse link
Notch signaling pathway involved in arterial endothelial cell fate commitment term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dll1 delta like canonical Notch ligand 1 involved_in IMP (PMID:19144989) UniProt PMID:19144989 NCBI chr17:15,587,616...15,597,275
Ensembl chr17:15,587,616...15,597,134 		JBrowse link
positive regulation of blood vessel endothelial cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mir34a microRNA 34a involved_in ISO (PMID:24792364) BHF-UCL PMID:24792364 NCBI chr 4:150,152,911...150,153,012
Ensembl chr 4:150,152,911...150,153,012 		JBrowse link
positive regulation of endothelial cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acvrl1 activin A receptor, type II-like 1 involved_in IDA (PMID:20406889) DFLAT PMID:20406889 NCBI chr15:101,026,403...101,043,217
Ensembl chr15:101,026,403...101,043,217 		JBrowse link
G Atoh8 atonal bHLH transcription factor 8 involved_in ISS
ISO 		UniProt
GO_Central		 GO_REF:0000024 GO_REF:0000119 NCBI chr 6:72,183,158...72,212,765
Ensembl chr 6:72,183,161...72,212,561 		JBrowse link
G Bmp4 bone morphogenetic protein 4 involved_in IDA (PMID:20406889) DFLAT PMID:20406889 NCBI chr14:46,620,982...46,628,126
Ensembl chr14:46,620,977...46,628,126 		JBrowse link
G Bmp6 bone morphogenetic protein 6 involved_in IDA (PMID:20406889) DFLAT PMID:20406889 NCBI chr13:38,529,098...38,684,283
Ensembl chr13:38,529,083...38,684,278 		JBrowse link
G Btg1 BTG anti-proliferation factor 1 involved_in ISS
ISO 		UniProt
GO_Central		 GO_REF:0000024 GO_REF:0000119 NCBI chr10:96,452,863...96,458,675
Ensembl chr10:96,452,868...96,458,671 		JBrowse link
G Ctnnb1 catenin beta 1 acts_upstream_of_or_within IMP (PMID:18231602) MGI PMID:18231602 NCBI chr 9:120,762,466...120,789,573
Ensembl chr 9:120,758,282...120,789,573 		JBrowse link
G Etv2 ets variant 2 acts_upstream_of_or_within IDA (PMID:18462699) MGI PMID:18462699 NCBI chr 7:30,333,041...30,335,934
Ensembl chr 7:30,333,041...30,335,277 		JBrowse link
G Gdf2 growth differentiation factor 2 involved_in IDA (PMID:20406889) DFLAT PMID:20406889 NCBI chr14:33,662,996...33,669,155
Ensembl chr14:33,662,996...33,669,155 		JBrowse link
G Mir126a microRNA 126a ISO RGD PMID:32160957 RGD:401851064 NCBI chr 2:26,481,369...26,481,441
Ensembl chr 2:26,481,369...26,481,441 		JBrowse link
G Mir150 microRNA 150 involved_in ISO (PMID:23765923) BHF-UCL PMID:23765923 NCBI chr 7:44,771,181...44,771,245
Ensembl chr 7:44,771,181...44,771,245 		JBrowse link
G Mir181a-1 microRNA 181a-1 involved_in ISO (PMID:22232059) BHF-UCL PMID:22232059 NCBI chr 1:137,894,193...137,894,279
Ensembl chr 1:137,894,193...137,894,279 		JBrowse link
G Mir181a-2 microRNA 181a-2 involved_in ISO (PMID:22232059) BHF-UCL PMID:22232059 NCBI chr 2:38,742,747...38,742,822
Ensembl chr 2:38,742,747...38,742,822 		JBrowse link
G Mir181b-1 microRNA 181b-1 involved_in ISO (PMID:22232059) BHF-UCL PMID:22232059 NCBI chr 1:137,894,377...137,894,456
Ensembl chr 1:137,894,377...137,894,456 		JBrowse link
G Mir181b-2 microRNA 181b-2 involved_in ISO (PMID:22232059) BHF-UCL PMID:22232059 NCBI chr 2:38,743,842...38,743,930
Ensembl chr 2:38,743,842...38,743,930 		JBrowse link
G Mir200c microRNA 200c involved_in ISO (PMID:23765923) BHF-UCL PMID:23765923 NCBI chr 6:124,695,285...124,695,353
Ensembl chr 6:124,695,285...124,695,353 		JBrowse link
G Mir21a microRNA 21a involved_in ISO (PMID:24356956) BHF-UCL PMID:24356956 NCBI chr11:86,474,893...86,474,984
Ensembl chr11:86,474,893...86,474,984 		JBrowse link
G Mir99b microRNA 99b involved_in ISO (PMID:22232059) BHF-UCL PMID:22232059 NCBI chr17:18,050,450...18,050,519
Ensembl chr17:18,050,450...18,050,519 		JBrowse link
G Mrtfa myocardin related transcription factor A ISO RGD PMID:23624342 RGD:529317032 NCBI chr15:80,896,482...81,074,937
Ensembl chr15:80,896,482...81,074,958 		JBrowse link
G Notch1 notch 1 involved_in ISO
IEA 		RGD
GO_Central
Ensembl		 PMID:19109527 GO_REF:0000096 GO_REF:0000107 RGD:2325303 NCBI chr 2:26,347,914...26,393,834
Ensembl chr 2:26,347,915...26,406,675 		JBrowse link
G Tmem100 transmembrane protein 100 involved_in IMP (PMID:22783020) UniProt PMID:22783020 NCBI chr11:89,921,174...89,927,334
Ensembl chr11:89,921,174...89,927,334 		JBrowse link
G Vezf1 vascular endothelial zinc finger 1 involved_in ISO GO_Central GO_REF:0000119 NCBI chr11:87,959,084...87,975,555
Ensembl chr11:87,959,105...87,975,555 		JBrowse link
positive regulation of endothelial tube morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alox12 arachidonate 12-lipoxygenase involved_in ISO
IEA 		RGD
Ensembl
GO_Central		 PMID:10733500 GO_REF:0000096 GO_REF:0000107 RGD:2313864 NCBI chr11:70,132,283...70,146,206
Ensembl chr11:70,132,283...70,146,179 		JBrowse link
G Itgax integrin alpha X involved_in ISO
IEA 		GO_Central
Ensembl		 GO_REF:0000107 GO_REF:0000119 NCBI chr 7:127,728,697...127,749,829
Ensembl chr 7:127,728,719...127,749,829 		JBrowse link
G Lcn2 lipocalin 2 involved_in ISO RGD
GO_Central		 PMID:25557118 GO_REF:0000096 RGD:126790477 NCBI chr 2:32,274,649...32,277,751
Ensembl chr 2:32,274,645...32,278,264 		JBrowse link
G Mir21a microRNA 21a ISO RGD PMID:31759996 RGD:41410819 NCBI chr11:86,474,893...86,474,984
Ensembl chr11:86,474,893...86,474,984 		JBrowse link
positive regulation of establishment of endothelial barrier term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Add1 adducin 1 involved_in IBA
IMP
ISO 		(PMID:25978380) GO_Central
CAFA		 PMID:25978380 GO_REF:0000033 GO_REF:0000119 NCBI chr 5:34,731,008...34,789,652
Ensembl chr 5:34,731,008...34,789,652 		JBrowse link
G Akap11 A kinase anchor protein 11 involved_in ISO RGD
GO_Central		 PMID:25188285 GO_REF:0000096 RGD:14348953 NCBI chr14:78,729,686...78,774,306
Ensembl chr14:78,729,686...78,774,248 		JBrowse link
G Cdh5 cadherin 5 involved_in IEA
ISO 		Ensembl
GO_Central		 GO_REF:0000107 GO_REF:0000119 NCBI chr 8:104,828,247...104,871,136
Ensembl chr 8:104,828,257...104,871,143 		JBrowse link
G Cldn5 claudin 5 involved_in IEA
ISO 		Ensembl
GO_Central		 GO_REF:0000107 GO_REF:0000119 NCBI chr16:18,595,597...18,597,012
Ensembl chr16:18,595,597...18,597,012 		JBrowse link
G Dicer1 dicer 1, ribonuclease type III involved_in ISO RGD
GO_Central		 PMID:23239824 GO_REF:0000096 RGD:149735901 NCBI chr12:104,654,001...104,718,331
Ensembl chr12:104,654,001...104,718,211 		JBrowse link
G F11r F11 receptor involved_in IEA
ISO 		Ensembl
GO_Central		 GO_REF:0000107 GO_REF:0000119 NCBI chr 1:171,265,129...171,292,161
Ensembl chr 1:171,265,103...171,292,171 		JBrowse link
G Il4 interleukin 4 involved_in ISO (PMID:24280217) AgBase PMID:24280217 NCBI chr11:53,503,287...53,509,492
Ensembl chr11:53,493,809...53,509,496 		JBrowse link
G Proc protein C involved_in ISS
ISO 		UniProt
GO_Central		 GO_REF:0000024 GO_REF:0000119 NCBI chr18:32,256,179...32,272,623
Ensembl chr18:32,256,179...32,272,623 		JBrowse link
G S1pr2 sphingosine-1-phosphate receptor 2 involved_in ISO
IEA 		GO_Central
Ensembl		 GO_REF:0000107 GO_REF:0000119 NCBI chr 9:20,877,248...20,888,089
Ensembl chr 9:20,873,657...20,888,077 		JBrowse link
regulation of endothelial cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apold1 apolipoprotein L domain containing 1 involved_in ISO
IBA 		RGD
GO_Central		 PMID:15102925 GO_REF:0000033 RGD:1303988 NCBI chr 6:134,958,964...134,963,799
Ensembl chr 6:134,958,681...134,963,799 		JBrowse link
G Bmpr1a bone morphogenetic protein receptor, type 1A NOT|involved_in IDA (PMID:20406889) DFLAT PMID:20406889 NCBI chr14:34,133,018...34,225,335
Ensembl chr14:34,132,691...34,225,298 		JBrowse link
G Ceacam1 CEA cell adhesion molecule 1 involved_in IDA (PMID:16680193) UniProt PMID:16680193 NCBI chr 7:25,161,127...25,177,072
Ensembl chr 7:25,161,132...25,177,028 		JBrowse link
G Cul7 cullin 7 involved_in NAS (PMID:12904573) UniProt PMID:12904573 NCBI chr17:46,961,264...46,975,290
Ensembl chr17:46,961,263...46,975,290 		JBrowse link
G Vegfa vascular endothelial growth factor A acts_upstream_of_or_within IDA (PMID:18772315) MGI PMID:18772315 NCBI chr17:46,327,919...46,343,303
Ensembl chr17:46,327,919...46,343,295 		JBrowse link
regulation of endothelial tube morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adamts12 ADAM metallopeptidase with thrombospondin type 1 motif 12 involved_in IEA
ISO 		Ensembl
GO_Central		 GO_REF:0000107 GO_REF:0000119 NCBI chr15:11,064,781...11,349,321
Ensembl chr15:11,064,876...11,349,317 		JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 involved_in IEA
ISO 		Ensembl
GO_Central		 GO_REF:0000107 GO_REF:0000119 NCBI chr 5:92,494,497...92,496,748
Ensembl chr 5:92,494,497...92,496,748 		JBrowse link
G Fgf1 fibroblast growth factor 1 involved_in ISS
ISO 		UniProt
GO_Central		 GO_REF:0000024 GO_REF:0000119 NCBI chr18:38,971,725...39,062,532
Ensembl chr18:38,971,726...39,062,525 		JBrowse link
G Foxp1 forkhead box P1 involved_in ISO GO_Central GO_REF:0000119 NCBI chr 6:98,902,303...99,510,587
Ensembl chr 6:98,902,299...99,499,682 		JBrowse link
regulation of establishment of endothelial barrier term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ikbkb inhibitor of kappaB kinase beta involved_in ISO GO_Central GO_REF:0000119 NCBI chr 8:23,149,228...23,196,605
Ensembl chr 8:23,149,228...23,196,605 		JBrowse link
G Il1b interleukin 1 beta involved_in ISO
IEA 		GO_Central
Ensembl		 GO_REF:0000107 GO_REF:0000119 NCBI chr 2:129,206,490...129,213,059
Ensembl chr 2:129,206,490...129,213,059 		JBrowse link
G Plcb1 phospholipase C, beta 1 involved_in IMP (PMID:27653213) UniProt PMID:27653213 NCBI chr 2:134,628,084...135,317,178
Ensembl chr 2:134,627,987...135,317,178 		JBrowse link
G Ppp1r12a protein phosphatase 1, regulatory subunit 12A NOT|involved_in ISO (PMID:25816133) UniProt PMID:25816133 NCBI chr10:107,997,913...108,115,846
Ensembl chr10:107,998,054...108,120,336 		JBrowse link
G Rock1 Rho-associated coiled-coil containing protein kinase 1 involved_in IEA
ISO 		Ensembl
GO_Central		 GO_REF:0000107 GO_REF:0000119 NCBI chr18:10,064,401...10,182,225
Ensembl chr18:10,064,401...10,182,045 		JBrowse link
G Rock2 Rho-associated coiled-coil containing protein kinase 2 involved_in ISO GO_Central GO_REF:0000119 NCBI chr12:16,944,808...17,038,275
Ensembl chr12:16,944,896...17,037,824 		JBrowse link
G Tnf tumor necrosis factor involved_in IEA
ISO 		Ensembl
GO_Central		 GO_REF:0000107 GO_REF:0000119 NCBI chr17:35,418,343...35,420,983
Ensembl chr17:35,418,357...35,420,983 		JBrowse link
G Tnfrsf1a tumor necrosis factor receptor superfamily, member 1a involved_in ISO
IEA 		GO_Central
Ensembl		 GO_REF:0000107 GO_REF:0000119 NCBI chr 6:125,326,686...125,339,446
Ensembl chr 6:125,326,325...125,339,447 		JBrowse link
G Vcl vinculin involved_in ISO
IEA 		GO_Central
Ensembl		 GO_REF:0000107 GO_REF:0000119 NCBI chr14:20,979,436...21,083,744
Ensembl chr14:20,979,466...21,083,744 		JBrowse link
G Zdhhc21 zinc finger, DHHC domain containing 21 involved_in IMP (PMID:27653213) UniProt PMID:27653213 NCBI chr 4:82,716,975...82,778,892
Ensembl chr 4:82,716,975...82,778,195 		JBrowse link
venous endothelial cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Notch1 notch 1 involved_in IMP (PMID:20890042) BHF-UCL PMID:20890042 NCBI chr 2:26,347,914...26,393,834
Ensembl chr 2:26,347,915...26,406,675 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 28626
    developmental process 7547
      anatomical structure development 7011
        tissue development 2410
          epithelium development 1493
            endothelium development 176
              endocardial endothelium development 0
              endothelial cell differentiation + 149
              glomerular endothelium development + 6
              morphogenesis of an endothelium + 20
paths to the root