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ONTOLOGY REPORT - ANNOTATIONS

Term:outflow tract morphogenesis
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Accession:GO:0003151 term browser browse the term
Definition:The process in which the anatomical structures of the outflow tract are generated and organized. The outflow tract is the portion of the heart through which blood flows into the arteries.


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outflow tract morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ankrd11 ankyrin repeat domain containing 11 acts_upstream_of_or_within ISO (PMID:38951500) RGD PMID:38951500 NCBI chr19:67,848,836...68,007,491
Ensembl chr19:67,848,844...68,007,491 		JBrowse link
G Atf2 activating transcription factor 2 acts_upstream_of_or_within ISO MGI:1857283 (PMID:17767158) RGD PMID:17767158 NCBI chr 3:79,125,814...79,202,896
Ensembl chr 3:79,126,705...79,202,745 		JBrowse link
G Bmp4 bone morphogenetic protein 4 involved_in ISO
IEA 		RNAcentral:URS00002075FA_10090|RNAcentral:URS0000574A2C_10090|RNAcentral:URS000075EEC2_10090 (PMID:21145505)
GO_REF:0000107 		RGD
Ensembl		 PMID:21145505 GO_REF:0000107 NCBI chr15:22,098,191...22,113,145
Ensembl chr15:22,098,470...22,105,172 		JBrowse link
G Bmpr1a bone morphogenetic protein receptor type 1A involved_in ISO
IEA 		(PMID:15073157)
GO_REF:0000107 		RGD
Ensembl		 PMID:15073157 GO_REF:0000107 NCBI chr16:9,740,751...9,786,861
Ensembl chr16:9,742,875...9,786,861 		JBrowse link
G Bmpr2 bone morphogenetic protein receptor type 2 involved_in ISO
IEA 		(PMID:19409885)
GO_REF:0000107 		RGD
Ensembl		 PMID:19409885 GO_REF:0000107 NCBI chr 9:68,685,942...68,801,353
Ensembl chr 9:68,685,988...68,801,350 		JBrowse link
G Cited2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 acts_upstream_of_or_within
involved_in 		ISO MGI:2179740 (PMID:11694877)
(PMID:15475956) 		RGD PMID:11694877 PMID:15475956 NCBI chr 1:14,132,303...14,134,746
Ensembl chr 1:14,103,457...14,134,782 		JBrowse link
G Crkl CRK like proto-oncogene, adaptor protein acts_upstream_of_or_within ISO MGI:5763397|MGI:5763398 (PMID:25658046) RGD PMID:25658046 NCBI chr11:97,033,033...97,067,457
Ensembl chr11:97,024,782...97,067,457 		JBrowse link
G Ctnnb1 catenin beta 1 involved_in IEA
ISO 		GO_REF:0000107
(PMID:12464179) 		Ensembl
RGD		 PMID:12464179 GO_REF:0000107 NCBI chr 8:129,517,576...129,544,661
Ensembl chr 8:129,517,545...129,544,662 		JBrowse link
G Dhrs3 dehydrogenase/reductase 3 acts_upstream_of_or_within ISO
IEA 		MGI:5007106 (PMID:24005908)
GO_REF:0000107 		RGD
Ensembl		 PMID:24005908 GO_REF:0000107 NCBI chr 5:156,747,939...156,782,420
Ensembl chr 5:162,031,386...162,065,653 		JBrowse link
G Dvl1 dishevelled segment polarity protein 1 involved_in ISO
IEA 		UniProtKB:Q60838 (PMID:22841628)
GO_REF:0000107 		RGD
Ensembl		 PMID:22841628 GO_REF:0000107 NCBI chr 5:171,738,911...171,750,967
Ensembl chr 5:171,739,133...171,750,966 		JBrowse link
G Dvl2 dishevelled segment polarity protein 2 involved_in ISO
IEA 		UniProtKB:P51141 (PMID:12464179), (PMID:22841628)
GO_REF:0000107 		RGD
Ensembl		 PMID:12464179 PMID:22841628 GO_REF:0000107 NCBI chr10:54,723,356...54,732,823
Ensembl chr10:55,222,056...55,231,506 		JBrowse link
G Eln elastin involved_in ISO
IEA 		(PMID:8132745)
GO_REF:0000107 		RGD
Ensembl		 PMID:8132745 GO_REF:0000107 NCBI chr12:27,604,983...27,648,413
Ensembl chr12:27,604,680...27,648,413 		JBrowse link
G Ext1 exostosin glycosyltransferase 1 acts_upstream_of_or_within ISO (PMID:26295701) RGD PMID:26295701 NCBI chr 7:86,265,651...86,544,488
Ensembl chr 7:86,259,900...86,544,567 		JBrowse link
G Eya1 EYA transcriptional coactivator and phosphatase 1 acts_upstream_of_or_within ISO MGI:102780|MGI:98493|MGI:99604 (PMID:21364285) RGD PMID:21364285 NCBI chr 5:9,646,599...9,884,609
Ensembl chr 5:9,646,591...9,884,614 		JBrowse link
G Fgf8 fibroblast growth factor 8 acts_upstream_of_or_within ISO
IEA 		MGI:102780|MGI:109344|MGI:98493 (PMID:21364285)
GO_REF:0000107 		RGD
Ensembl		 PMID:21364285 GO_REF:0000107 NCBI chr 1:254,533,504...254,539,605
Ensembl chr 1:254,533,504...254,539,605 		JBrowse link
G Foxh1 forkhead box H1 involved_in ISO
IEA 		(PMID:15363409)
GO_REF:0000107 		RGD
Ensembl		 PMID:15363409 GO_REF:0000107 NCBI chr 7:110,268,608...110,272,105
Ensembl chr 7:110,268,612...110,270,692 		JBrowse link
G Fzd1 frizzled class receptor 1 acts_upstream_of_or_within ISO MGI:1888513 (PMID:20940229) RGD PMID:20940229 NCBI chr 4:29,310,303...29,314,701
Ensembl chr 4:30,247,228...30,833,176 		JBrowse link
G Fzd2 frizzled class receptor 2 acts_upstream_of_or_within ISO
IEA 		MGI:1196625 (PMID:20940229)
GO_REF:0000107 		RGD
Ensembl		 PMID:20940229 GO_REF:0000107 NCBI chr10:88,061,988...88,063,898
Ensembl chr10:88,061,667...88,065,396 		JBrowse link
G Gja5 gap junction protein, alpha 5 involved_in ISO
IEA 		(PMID:22199024)
GO_REF:0000107 		RGD
Ensembl		 PMID:22199024 GO_REF:0000107 NCBI chr 2:187,291,227...187,310,770
Ensembl chr 2:187,234,674...187,318,512 		JBrowse link
G Greb1l GREB1 like retinoic acid receptor coactivator acts_upstream_of_or_within ISO
IEA 		(PMID:37852253)
GO_REF:0000107 		RGD
Ensembl		 PMID:37852253 GO_REF:0000107 NCBI chr18:1,392,330...1,629,483
Ensembl chr18:1,766,214...1,900,178 		JBrowse link
G Hand2 heart and neural crest derivatives expressed 2 involved_in ISO
IEA 		(PMID:19008477)
GO_REF:0000107 		RGD
Ensembl		 PMID:19008477 GO_REF:0000107 NCBI chr16:37,928,145...37,931,488
Ensembl chr16:37,928,145...37,931,488 		JBrowse link
G Hes1 hes family bHLH transcription factor 1 acts_upstream_of_or_within
involved_in 		ISO
IEA 		(PMID:19609448)
GO_REF:0000107
(PMID:20122914) 		RGD
Ensembl		 PMID:19609448 PMID:20122914 GO_REF:0000107 NCBI chr11:84,210,632...84,213,045
Ensembl chr11:84,210,633...84,213,061 		JBrowse link
G Hey1 hes-related family bHLH transcription factor with YRPW motif 1 involved_in ISO
IEA 		UniProtKB:Q9DBX7 (PMID:17303760)
GO_REF:0000117 		RGD
UniProt		 PMID:17303760 GO_REF:0000117 NCBI chr 2:95,003,935...95,006,457
Ensembl chr 2:95,002,943...95,007,624 		JBrowse link
G Hey2 hes-related family bHLH transcription factor with YRPW motif 2 involved_in ISO
IEA 		(PMID:12372254)
GO_REF:0000117
GO_REF:0000107 		RGD
UniProt
Ensembl		 PMID:12372254 GO_REF:0000107 GO_REF:0000117 NCBI chr 1:28,641,100...28,651,187
Ensembl chr 1:28,641,057...28,651,187 		JBrowse link
G Heyl hes-related family bHLH transcription factor with YRPW motif-like involved_in ISO
IEA 		UniProtKB:Q9WV93 (PMID:17303760)
GO_REF:0000117
GO_REF:0000107 		RGD
UniProt
Ensembl		 PMID:17303760 GO_REF:0000107 GO_REF:0000117 NCBI chr 5:135,508,160...135,525,152
Ensembl chr 5:140,793,271...140,810,262 		JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha acts_upstream_of_or_within ISO
IEA 		MGI:1857719 (PMID:9436976)
GO_REF:0000107 		RGD
Ensembl		 PMID:9436976 GO_REF:0000107 NCBI chr 6:98,357,788...98,405,068
Ensembl chr 6:98,359,910...98,405,323 		JBrowse link
G Ilk integrin-linked kinase involved_in IEA
ISO 		GO_REF:0000107
(PMID:24131868) 		Ensembl
RGD		 PMID:24131868 GO_REF:0000107 NCBI chr 1:169,500,716...169,506,972
Ensembl chr 1:169,498,681...169,506,964 		JBrowse link
G Isl1 ISL LIM homeobox 1 involved_in ISO
IEA 		UniProtKB:Q02248 (PMID:17519333)
GO_REF:0000107 		RGD
Ensembl		 PMID:17519333 GO_REF:0000107 NCBI chr 2:49,813,618...49,823,442
Ensembl chr 2:49,813,618...49,823,442 		JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit acts_upstream_of_or_within ISO
IEA 		MGI:2149630 (PMID:10352021)
GO_REF:0000107 		RGD
Ensembl		 PMID:10352021 GO_REF:0000107 NCBI chr 5:115,009,900...115,012,993
Ensembl chr 5:114,973,151...115,013,285 		JBrowse link
G Lrp2 LDL receptor related protein 2 acts_upstream_of_or_within ISO
IEA 		(PMID:34463328)
GO_REF:0000107 		RGD
Ensembl		 PMID:34463328 GO_REF:0000107 NCBI chr 3:74,597,148...74,754,535
Ensembl chr 3:74,597,148...74,754,535 		JBrowse link
G Lrp6 LDL receptor related protein 6 acts_upstream_of ISO MGI:98958 (PMID:19056682) RGD PMID:19056682 NCBI chr 4:168,997,937...169,131,716
Ensembl chr 4:169,000,968...169,131,716 		JBrowse link
G Mef2c myocyte enhancer factor 2C acts_upstream_of_or_within ISO MGI:97350 (PMID:19035347) RGD PMID:19035347 NCBI chr 2:15,708,732...15,871,639
Ensembl chr 2:15,708,924...15,871,640 		JBrowse link
G Msx2 msh homeobox 2 acts_upstream_of_or_within ISO
IEA 		MGI:97168 (PMID:17601530)
GO_REF:0000107 		RGD
Ensembl		 PMID:17601530 GO_REF:0000107 NCBI chr17:11,102,284...11,107,949
Ensembl chr17:11,102,247...11,107,945 		JBrowse link
G Nedd4 NEDD4 E3 ubiquitin protein ligase acts_upstream_of_or_within ISO MGI:3799317|MGI:98737 (PMID:20026598) RGD PMID:20026598 NCBI chr 8:82,264,751...82,349,642
Ensembl chr 8:82,264,649...82,349,633 		JBrowse link
G Nipbl NIPBL, cohesin loading factor involved_in ISO
IEA 		(PMID:19242925)
GO_REF:0000107 		RGD
Ensembl		 PMID:19242925 GO_REF:0000107 NCBI chr 2:59,126,676...59,314,841
Ensembl chr 2:59,126,676...59,293,277 		JBrowse link
G Nkx2-5 NK2 homeobox 5 acts_upstream_of_or_within ISO
IEA 		MGI:99458 (PMID:16510504), (PMID:19035347)
GO_REF:0000107 		RGD
Ensembl		 PMID:16510504 PMID:19035347 GO_REF:0000107 NCBI chr10:16,844,888...16,851,458
Ensembl chr10:16,848,582...16,851,452 		JBrowse link
G Nog noggin involved_in IEA
ISO 		GO_REF:0000107
(PMID:17218603) 		Ensembl
RGD		 PMID:17218603 GO_REF:0000107 NCBI chr10:74,625,874...74,627,501
Ensembl chr10:74,625,875...74,628,103 		JBrowse link
G Notch1 notch receptor 1 involved_in ISO
IEA 		(PMID:18593716)
GO_REF:0000107 		RGD
Ensembl		 PMID:18593716 GO_REF:0000107 NCBI chr 3:29,676,040...29,721,613
Ensembl chr 3:29,676,171...29,721,613 		JBrowse link
G Npy1r neuropeptide Y receptor Y1 involved_in ISO (PMID:19593212) RGD PMID:19593212 NCBI chr16:27,804,416...27,814,070
Ensembl chr16:27,804,416...27,813,387 		JBrowse link
G Npy2r neuropeptide Y receptor Y2 involved_in ISO (PMID:19593212) RGD PMID:19593212 NCBI chr 2:170,200,027...170,210,286
Ensembl chr 2:170,200,027...170,210,448 		JBrowse link
G Npy5r neuropeptide Y receptor Y5 involved_in ISO
IEA 		(PMID:19593212)
GO_REF:0000107 		RGD
Ensembl		 PMID:19593212 GO_REF:0000107 NCBI chr16:27,822,055...27,830,012
Ensembl chr16:27,816,065...27,830,290 		JBrowse link
G Pitx2 paired-like homeodomain 2 involved_in ISO (PMID:12464179) RGD PMID:12464179 NCBI chr 2:220,391,417...220,411,588
Ensembl chr 2:220,391,888...220,411,591 		JBrowse link
G Plxnd1 plexin D1 acts_upstream_of_or_within
involved_in 		ISO
IEA 		MGI:5544786 (PMID:23918385)
GO_REF:0000117
GO_REF:0000107 		RGD
UniProt
Ensembl		 PMID:23918385 GO_REF:0000107 GO_REF:0000117 NCBI chr 4:150,675,377...150,715,706
Ensembl chr 4:150,675,377...150,715,566 		JBrowse link
G Prickle1 prickle planar cell polarity protein 1 involved_in IEA
ISO 		GO_REF:0000107
MGI:5297388|MGI:5645931 (PMID:25190059), (PMID:26883626) 		Ensembl
RGD		 PMID:25190059 PMID:26883626 GO_REF:0000107 NCBI chr 7:126,518,587...126,614,581
Ensembl chr 7:126,518,587...126,614,581 		JBrowse link
G Rbpj recombination signal binding protein for immunoglobulin kappa J region involved_in ISO (PMID:14701881) RGD PMID:14701881 NCBI chr14:61,551,366...61,736,220
Ensembl chr14:61,551,366...61,736,307 		JBrowse link
G Ryr1 ryanodine receptor 1 involved_in ISS
ISO 		GO_REF:0000024
(PMID:18003898) 		UniProt
RGD		 PMID:18003898 GO_REF:0000024 NCBI chr 1:93,420,078...93,551,305
Ensembl chr 1:93,420,078...93,551,305 		JBrowse link
G Sec24b SEC24 homolog B, COPII coat complex component acts_upstream_of_or_within ISO MGI:4440621 (PMID:20215345) RGD PMID:20215345 NCBI chr 2:221,236,897...221,306,986
Ensembl chr 2:221,236,898...221,306,919 		JBrowse link
G Sema3c semaphorin 3C involved_in ISO
IEA 		(PMID:19666519)
GO_REF:0000107 		RGD
Ensembl		 PMID:19666519 GO_REF:0000107 NCBI chr 4:17,583,212...17,747,234
Ensembl chr 4:18,538,454...18,701,740 		JBrowse link
G Sfrp2 secreted frizzled-related protein 2 involved_in ISO
IEA 		(PMID:19593212)
GO_REF:0000107 		RGD
Ensembl		 PMID:19593212 GO_REF:0000107 NCBI chr 2:171,387,536...171,395,081
Ensembl chr 2:171,387,385...171,395,079 		JBrowse link
G Six1 SIX homeobox 1 acts_upstream_of_or_within ISO
IEA 		MGI:109344|MGI:98493|MGI:99604 (PMID:21364285)
GO_REF:0000107 		RGD
Ensembl		 PMID:21364285 GO_REF:0000107 NCBI chr 6:97,482,617...97,487,853
Ensembl chr 6:97,482,617...97,487,853 		JBrowse link
G Smarca4 SWI/SNF related BAF chromatin remodeling complex subunit ATPase 4 acts_upstream_of_or_within ISO MGI:3605892 (PMID:23319608) RGD PMID:23319608 NCBI chr 8:28,438,370...28,535,071
Ensembl chr 8:28,443,810...28,535,070 		JBrowse link
G Sox11 SRY-box transcription factor 11 involved_in ISS
IEA
ISO 		GO_REF:0000024
GO_REF:0000107
(PMID:15254231) 		UniProt
Ensembl
RGD		 PMID:15254231 GO_REF:0000024 GO_REF:0000107 NCBI chr 6:49,736,773...49,738,794
Ensembl chr 6:49,736,304...49,738,691 		JBrowse link
G Sox17 SRY-box transcription factor 17 involved_in ISO
IEA 		UniProtKB:P43680 (PMID:17610846)
GO_REF:0000107 		RGD
Ensembl		 PMID:17610846 GO_REF:0000107 NCBI chr 5:19,814,345...19,819,859
Ensembl chr 5:19,814,360...19,819,854 		JBrowse link
G Tbx1 T-box transcription factor 1 involved_in
acts_upstream_of_or_within 		ISS
ISO 		GO_REF:0000024
MGI:102780|MGI:109344|MGI:2179190|MGI:3664784|MGI:99604 (PMID:17916582), (PMID:18583714), (PMID:21364285) 		UniProt
RGD		 PMID:17916582 PMID:18583714 PMID:21364285 GO_REF:0000024 NCBI chr11:95,913,610...95,923,392
Ensembl chr11:95,913,610...95,923,392 		JBrowse link
G Tbx2 T-box transcription factor 2 involved_in ISO
IEA 		(PMID:15042700), (PMID:15459098), (PMID:22186728)
GO_REF:0000107 		RGD
Ensembl		 PMID:15042700 PMID:15459098 PMID:22186728 GO_REF:0000107 NCBI chr10:71,177,082...71,186,275
Ensembl chr10:71,177,082...71,186,275 		JBrowse link
G Tbx20 T-box transcription factor 20 involved_in ISO
IEA 		(PMID:15843409)
GO_REF:0000107 		RGD
Ensembl		 PMID:15843409 GO_REF:0000107 NCBI chr 8:31,475,963...31,534,051
Ensembl chr 8:31,475,963...31,534,009 		JBrowse link
G Tbx3 T-box transcription factor 3 acts_upstream_of_or_within ISO
IEA 		MGI:2655214 (PMID:18723448)
GO_REF:0000107 		RGD
Ensembl		 PMID:18723448 GO_REF:0000107 NCBI chr12:42,540,378...42,555,490
Ensembl chr12:42,540,378...42,554,171 		JBrowse link
G Tfap2a transcription factor AP-2 alpha acts_upstream_of_or_within ISO MGI:2176682 (PMID:11744375) RGD PMID:11744375 NCBI chr17:24,230,064...24,253,219
Ensembl chr17:24,229,910...24,253,219 		JBrowse link
G Tgfb2 transforming growth factor, beta 2 involved_in ISO
IEA 		(PMID:22186728)
GO_REF:0000107 		RGD
Ensembl		 PMID:22186728 GO_REF:0000107 NCBI chr13:100,691,540...100,793,227
Ensembl chr13:100,692,953...100,792,856 		JBrowse link
G Tgfbr2 transforming growth factor, beta receptor 2 involved_in ISO
IEA 		(PMID:17050629)
GO_REF:0000107 		RGD
Ensembl		 PMID:17050629 GO_REF:0000107 NCBI chr 8:124,672,677...124,761,741
Ensembl chr 8:124,674,986...124,761,469 		JBrowse link
G Tgfbr3 transforming growth factor beta receptor 3 involved_in ISO (PMID:17704211) RGD PMID:17704211 NCBI chr14:2,634,294...2,810,269
Ensembl chr14:2,634,188...2,810,271 		JBrowse link
G Thbs1 thrombospondin 1 acts_upstream_of_or_within ISO MGI:97297 (PMID:20026598) RGD PMID:20026598 NCBI chr 3:125,510,250...125,525,402
Ensembl chr 3:125,510,250...125,525,402 		JBrowse link
G Vegfa vascular endothelial growth factor A involved_in ISO (PMID:18093989) RGD PMID:18093989 NCBI chr 9:22,452,854...22,468,194
Ensembl chr 9:22,439,392...22,468,194 		JBrowse link
G Wnt11 Wnt family member 11 acts_upstream_of_or_within ISO
IEA 		MGI:2665014 (PMID:17767158)
GO_REF:0000107 		RGD
Ensembl		 PMID:17767158 GO_REF:0000107 NCBI chr 1:162,545,660...162,565,456
Ensembl chr 1:162,545,680...162,564,660 		JBrowse link
G Zfpm1 zinc finger protein, multitype 1 involved_in ISO
IEA 		(PMID:14614148)
GO_REF:0000107 		RGD
Ensembl		 PMID:14614148 GO_REF:0000107 NCBI chr19:50,334,352...50,391,029
Ensembl chr19:67,179,751...67,299,149 		JBrowse link
G Zfpm2 zinc finger protein, multitype 2 involved_in IEA GO_REF:0000117 UniProt GO_REF:0000117 NCBI chr 7:71,678,658...72,116,209
Ensembl chr 7:73,563,732...74,001,041 		JBrowse link
apoptotic process involved in outflow tract morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Foxc1 forkhead box C1 acts_upstream_of ISO
IEA 		MGI:1347481 (PMID:16839542)
GO_REF:0000107 		RGD
Ensembl		 PMID:16839542 GO_REF:0000107 NCBI chr17:32,840,119...32,844,100
Ensembl chr17:32,805,858...32,844,347 		JBrowse link
G Foxc2 forkhead box C2 acts_upstream_of ISO MGI:1347466 (PMID:16839542) RGD PMID:16839542 NCBI chr19:66,094,718...66,097,420
Ensembl chr19:66,094,700...66,153,977 		JBrowse link
cardiac neural crest cell development involved in outflow tract morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dicer1 dicer 1 ribonuclease III acts_upstream_of_or_within ISO MGI:3589208 (PMID:21098571) RGD PMID:21098571 NCBI chr 6:129,392,298...129,457,252
Ensembl chr 6:129,396,014...129,457,252 		JBrowse link
G Hand2 heart and neural crest derivatives expressed 2 involved_in ISO
IEA 		(PMID:19008477)
GO_REF:0000107 		RGD
Ensembl		 PMID:19008477 GO_REF:0000107 NCBI chr16:37,928,145...37,931,488
Ensembl chr16:37,928,145...37,931,488 		JBrowse link
G Hes1 hes family bHLH transcription factor 1 acts_upstream_of_or_within ISO
IEA 		(PMID:19609448)
GO_REF:0000107 		RGD
Ensembl		 PMID:19609448 GO_REF:0000107 NCBI chr11:84,210,632...84,213,045
Ensembl chr11:84,210,633...84,213,061 		JBrowse link
G Jag1 jagged canonical Notch ligand 1 involved_in IEA
ISO 		GO_REF:0000107
(PMID:19509466) 		Ensembl
RGD		 PMID:19509466 GO_REF:0000107 NCBI chr 3:144,859,453...144,894,883
Ensembl chr 3:144,859,453...144,894,872 		JBrowse link
G Twist1 twist family bHLH transcription factor 1 acts_upstream_of_or_within ISO MGI:1857265 (PMID:18539270) RGD PMID:18539270 NCBI chr 6:56,402,309...56,404,303
Ensembl chr 6:56,398,061...56,404,965 		JBrowse link
cardiac neural crest cell migration involved in outflow tract morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdc42 cell division cycle 42 involved_in ISO (PMID:31219639) RGD PMID:31219639 NCBI chr 5:154,838,478...154,876,629
Ensembl chr 5:154,839,631...154,876,627 		JBrowse link
G Edn1 endothelin 1 involved_in ISO
IEA 		(PMID:31219639)
GO_REF:0000107 		RGD
Ensembl		 PMID:31219639 GO_REF:0000107 NCBI chr17:22,660,799...22,666,687
Ensembl chr17:22,660,799...22,666,687 		JBrowse link
G Ednra endothelin receptor type A involved_in IEA
ISO 		GO_REF:0000107
MGI:1857473|MGI:2687362 (PMID:31219639) 		Ensembl
RGD		 PMID:31219639 GO_REF:0000107 NCBI chr19:47,137,360...47,207,961
Ensembl chr19:47,137,771...47,201,284 		JBrowse link
G Folr1 folate receptor alpha involved_in ISO
IEA 		(PMID:17286298)
GO_REF:0000107 		RGD
Ensembl		 PMID:17286298 GO_REF:0000107 NCBI chr 1:156,219,460...156,238,436
Ensembl chr 1:165,631,462...165,642,669 		JBrowse link
G Hand2 heart and neural crest derivatives expressed 2 acts_upstream_of_or_within ISO
IEA 		MGI:2386570|MGI:3803647 (PMID:20144608)
GO_REF:0000107 		RGD
Ensembl		 PMID:20144608 GO_REF:0000107 NCBI chr16:37,928,145...37,931,488
Ensembl chr16:37,928,145...37,931,488 		JBrowse link
G Nrp1 neuropilin 1 NOT|involved_in ISO (PMID:26053665) RGD PMID:26053665 NCBI chr19:73,256,557...73,411,705
Ensembl chr19:73,256,557...73,411,702 		JBrowse link
G Pitx2 paired-like homeodomain 2 involved_in ISO (PMID:12464179) RGD PMID:12464179 NCBI chr 2:220,391,417...220,411,588
Ensembl chr 2:220,391,888...220,411,591 		JBrowse link
G Twist1 twist family bHLH transcription factor 1 acts_upstream_of_or_within ISO MGI:1857265 (PMID:18539270) RGD PMID:18539270 NCBI chr 6:56,402,309...56,404,303
Ensembl chr 6:56,398,061...56,404,965 		JBrowse link
cell proliferation involved in outflow tract morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hand2 heart and neural crest derivatives expressed 2 acts_upstream_of_or_within ISO
IEA 		MGI:2386570|MGI:3803647 (PMID:20144608)
GO_REF:0000107 		RGD
Ensembl		 PMID:20144608 GO_REF:0000107 NCBI chr16:37,928,145...37,931,488
Ensembl chr16:37,928,145...37,931,488 		JBrowse link
G Pitx2 paired-like homeodomain 2 acts_upstream_of_or_within ISO MGI:1857844|MGI:2445429 (PMID:16836994) RGD PMID:16836994 NCBI chr 2:220,391,417...220,411,588
Ensembl chr 2:220,391,888...220,411,591 		JBrowse link
negative regulation of apoptotic process involved in outflow tract morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Foxc1 forkhead box C1 acts_upstream_of_or_within ISO
IEA 		MGI:1347481 (PMID:16839542)
GO_REF:0000107 		RGD
Ensembl		 PMID:16839542 GO_REF:0000107 NCBI chr17:32,840,119...32,844,100
Ensembl chr17:32,805,858...32,844,347 		JBrowse link
G Foxc2 forkhead box C2 acts_upstream_of_or_within ISO MGI:1347466 (PMID:16839542) RGD PMID:16839542 NCBI chr19:66,094,718...66,097,420
Ensembl chr19:66,094,700...66,153,977 		JBrowse link
outflow tract septum morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acvr1 activin A receptor type 1 NOT|involved_in ISO (PMID:16140292) RGD PMID:16140292 NCBI chr 3:63,387,378...63,506,980
Ensembl chr 3:63,387,381...63,477,884 		JBrowse link
G Bmp4 bone morphogenetic protein 4 involved_in IEA
ISO 		GO_REF:0000107
(PMID:15070745), (PMID:18924235) 		Ensembl
RGD		 PMID:15070745 PMID:18924235 GO_REF:0000107 NCBI chr15:22,098,191...22,113,145
Ensembl chr15:22,098,470...22,105,172 		JBrowse link
G Bmpr1a bone morphogenetic protein receptor type 1A involved_in ISO
IEA 		(PMID:15073157)
GO_REF:0000107 		RGD
Ensembl		 PMID:15073157 GO_REF:0000107 NCBI chr16:9,740,751...9,786,861
Ensembl chr16:9,742,875...9,786,861 		JBrowse link
G Bmpr2 bone morphogenetic protein receptor type 2 NOT|involved_in ISO (PMID:19409885)
(PMID:12441304) 		RGD PMID:12441304 PMID:19409885 NCBI chr 9:68,685,942...68,801,353
Ensembl chr 9:68,685,988...68,801,350 		JBrowse link
G Dvl3 dishevelled segment polarity protein 3 acts_upstream_of_or_within ISO MGI:3831892 (PMID:19008950) RGD PMID:19008950 NCBI chr11:80,365,446...80,382,641
Ensembl chr11:93,869,834...93,886,903 		JBrowse link
G Eng endoglin involved_in ISO UniProtKB:P97471 (PMID:17628518) RGD PMID:17628518 NCBI chr 3:36,332,190...36,370,324
Ensembl chr 3:36,326,202...36,370,933 		JBrowse link
G Fgf8 fibroblast growth factor 8 involved_in ISO
IEA 		UniProtKB:P70323 (PMID:20807544)
GO_REF:0000107 		RGD
Ensembl		 PMID:20807544 GO_REF:0000107 NCBI chr 1:254,533,504...254,539,605
Ensembl chr 1:254,533,504...254,539,605 		JBrowse link
G Fgfr2 fibroblast growth factor receptor 2 acts_upstream_of_or_within ISO MGI:2153818 (PMID:16687131) RGD PMID:16687131 NCBI chr 1:194,175,703...194,280,914
Ensembl chr 1:194,175,705...194,280,914 		JBrowse link
G Gata6 GATA binding protein 6 involved_in ISO (PMID:19666519) RGD PMID:19666519 NCBI chr18:2,460,909...2,492,322
Ensembl chr18:2,458,253...2,492,322 		JBrowse link
G Isl1 ISL LIM homeobox 1 involved_in IEA
ISO 		GO_REF:0000107
UniProtKB:Q02248 (PMID:17519333) 		Ensembl
RGD		 PMID:17519333 GO_REF:0000107 NCBI chr 2:49,813,618...49,823,442
Ensembl chr 2:49,813,618...49,823,442 		JBrowse link
G Lrp2 LDL receptor related protein 2 involved_in ISS
ISO
IEA 		GO_REF:0000024
(PMID:26822476)
GO_REF:0000107 		UniProt
RGD
Ensembl		 PMID:26822476 GO_REF:0000024 GO_REF:0000107 NCBI chr 3:74,597,148...74,754,535
Ensembl chr 3:74,597,148...74,754,535 		JBrowse link
G Msx2 msh homeobox 2 acts_upstream_of_or_within ISO
IEA 		MGI:97168 (PMID:17601530)
GO_REF:0000107 		RGD
Ensembl		 PMID:17601530 GO_REF:0000107 NCBI chr17:11,102,284...11,107,949
Ensembl chr17:11,102,247...11,107,945 		JBrowse link
G Nkx2-5 NK2 homeobox 5 involved_in IEA
ISO 		GO_REF:0000107
(PMID:20807224) 		Ensembl
RGD		 PMID:20807224 GO_REF:0000107 NCBI chr10:16,844,888...16,851,458
Ensembl chr10:16,848,582...16,851,452 		JBrowse link
G Nrp1 neuropilin 1 involved_in ISO
IEA 		(PMID:26053665)
GO_REF:0000107 		RGD
Ensembl		 PMID:26053665 GO_REF:0000107 NCBI chr19:73,256,557...73,411,705
Ensembl chr19:73,256,557...73,411,702 		JBrowse link
G Nrp2 neuropilin 2 involved_in IEA
ISO 		GO_REF:0000107
UniProtKB:Q62181 (PMID:26053665) 		Ensembl
RGD		 PMID:26053665 GO_REF:0000107 NCBI chr 9:71,616,602...71,731,869
Ensembl chr 9:71,616,657...71,731,871 		JBrowse link
G Parva parvin, alpha involved_in ISS
ISO 		GO_REF:0000024
(PMID:19798050) 		UniProt
RGD		 PMID:19798050 GO_REF:0000024 NCBI chr 1:166,547,142...166,704,958
Ensembl chr 1:175,981,432...176,139,526 		JBrowse link
G Rara retinoic acid receptor, alpha acts_upstream_of_or_within
involved_in 		IEA GO_REF:0000107
GO_REF:0000117 		Ensembl
UniProt		 GO_REF:0000107 GO_REF:0000117 NCBI chr10:84,379,780...84,424,371
Ensembl chr10:84,389,622...84,425,160 		JBrowse link
G Rarb retinoic acid receptor, beta acts_upstream_of_or_within
involved_in 		IEA GO_REF:0000107
GO_REF:0000117 		Ensembl
UniProt		 GO_REF:0000107 GO_REF:0000117 NCBI chr15:10,837,252...11,482,037
Ensembl chr15:11,131,358...11,482,040 		JBrowse link
G Robo1 roundabout guidance receptor 1 involved_in ISO UniProtKB:Q7TPD3 (PMID:25691540) RGD PMID:25691540 NCBI chr11:24,067,869...25,108,694
Ensembl chr11:24,067,878...25,108,694 		JBrowse link
G Robo2 roundabout guidance receptor 2 involved_in ISO UniProtKB:O89026 (PMID:25691540) RGD PMID:25691540 NCBI chr11:26,015,919...27,583,750
Ensembl chr11:26,015,919...26,876,185 		JBrowse link
G Sema3c semaphorin 3C involved_in ISO
IEA 		UniProtKB:O35375|UniProtKB:P97333 (PMID:26053665)
GO_REF:0000107 		RGD
Ensembl		 PMID:26053665 GO_REF:0000107 NCBI chr 4:17,583,212...17,747,234
Ensembl chr 4:18,538,454...18,701,740 		JBrowse link
G Smad4 SMAD family member 4 involved_in IEA
ISO 		GO_REF:0000107
UniProtKB:Q63961 (PMID:17628518) 		Ensembl
RGD		 PMID:17628518 GO_REF:0000107 NCBI chr18:69,518,988...69,549,684
Ensembl chr18:69,518,988...69,549,684 		JBrowse link
G Smad6 SMAD family member 6 involved_in ISO
IEA 		(PMID:10655064)
GO_REF:0000107 		RGD
Ensembl		 PMID:10655064 GO_REF:0000107 NCBI chr 8:73,345,457...73,414,985
Ensembl chr 8:73,345,460...73,414,149 		JBrowse link
G Tbx1 T-box transcription factor 1 involved_in ISS
ISO 		GO_REF:0000024
(PMID:20807544) 		UniProt
RGD		 PMID:20807544 GO_REF:0000024 NCBI chr11:95,913,610...95,923,392
Ensembl chr11:95,913,610...95,923,392 		JBrowse link
G Tbx2 T-box transcription factor 2 involved_in ISO
IEA 		(PMID:15459098)
GO_REF:0000107 		RGD
Ensembl		 PMID:15459098 GO_REF:0000107 NCBI chr10:71,177,082...71,186,275
Ensembl chr10:71,177,082...71,186,275 		JBrowse link
G Tbx20 T-box transcription factor 20 involved_in ISO
IEA 		(PMID:18275040), (PMID:18834961)
GO_REF:0000117
GO_REF:0000107
(PMID:15843409) 		RGD
UniProt
Ensembl		 PMID:15843409 PMID:18275040 PMID:18834961 GO_REF:0000107 GO_REF:0000117 NCBI chr 8:31,475,963...31,534,051
Ensembl chr 8:31,475,963...31,534,009 		JBrowse link
G Tgfb2 transforming growth factor, beta 2 involved_in ISO
IEA 		(PMID:11390347), (PMID:9217007)
GO_REF:0000107 		RGD
Ensembl		 PMID:9217007 PMID:11390347 GO_REF:0000107 NCBI chr13:100,691,540...100,793,227
Ensembl chr13:100,692,953...100,792,856 		JBrowse link
G Tgfbr2 transforming growth factor, beta receptor 2 involved_in ISO
IEA 		(PMID:20652948)
GO_REF:0000107 		RGD
Ensembl		 PMID:20652948 GO_REF:0000107 NCBI chr 8:124,672,677...124,761,741
Ensembl chr 8:124,674,986...124,761,469 		JBrowse link
G Zfpm2 zinc finger protein, multitype 2 involved_in ISO
IEA 		(PMID:20807224)
GO_REF:0000107 		RGD
Ensembl		 PMID:20807224 GO_REF:0000107 NCBI chr 7:71,678,658...72,116,209
Ensembl chr 7:73,563,732...74,001,041 		JBrowse link
positive regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp4 bone morphogenetic protein 4 involved_in IEA
ISO 		GO_REF:0000107
UniProtKB:P23359 (PMID:23863481) 		Ensembl
RGD		 PMID:23863481 GO_REF:0000107 NCBI chr15:22,098,191...22,113,145
Ensembl chr15:22,098,470...22,105,172 		JBrowse link
G Bmp7 bone morphogenetic protein 7 involved_in ISO
IEA 		UniProtKB:P21275 (PMID:23863481)
GO_REF:0000107 		RGD
Ensembl		 PMID:23863481 GO_REF:0000107 NCBI chr 3:182,059,318...182,135,273
Ensembl chr 3:182,052,337...182,135,137 		JBrowse link
G Sema3c semaphorin 3C involved_in ISO
IEA 		(PMID:26053665)
GO_REF:0000107 		RGD
Ensembl		 PMID:26053665 GO_REF:0000107 NCBI chr 4:17,583,212...17,747,234
Ensembl chr 4:18,538,454...18,701,740 		JBrowse link
regulation of apoptotic process involved in outflow tract morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tgfb2 transforming growth factor, beta 2 involved_in ISO
IEA 		(PMID:11390347)
GO_REF:0000107 		RGD
Ensembl		 PMID:11390347 GO_REF:0000107 NCBI chr13:100,691,540...100,793,227
Ensembl chr13:100,692,953...100,792,856 		JBrowse link
regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Eng endoglin NOT|involved_in ISO (PMID:17628518) RGD PMID:17628518 NCBI chr 3:36,332,190...36,370,324
Ensembl chr 3:36,326,202...36,370,933 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20668
    developmental process 7294
      anatomical structure morphogenesis 3073
        outflow tract morphogenesis 90
          apoptotic process involved in outflow tract morphogenesis + 3
          cardiac neural crest cell delamination involved in outflow tract morphogenesis 0
          cardiac neural crest cell development involved in outflow tract morphogenesis + 15
          cell proliferation involved in outflow tract morphogenesis + 2
          outflow tract septum morphogenesis 29
          semaphorin-plexin signaling pathway involved in outflow tract morphogenesis + 0
Path 2
Term Annotations click to browse term
  biological_process 20668
    developmental process 7294
      anatomical structure development 6777
        multicellular organism development 5422
          system development 4701
            circulatory system development 1401
              heart development 757
                heart morphogenesis 301
                  outflow tract morphogenesis 90
                    apoptotic process involved in outflow tract morphogenesis + 3
                    cardiac neural crest cell delamination involved in outflow tract morphogenesis 0
                    cardiac neural crest cell development involved in outflow tract morphogenesis + 15
                    cell proliferation involved in outflow tract morphogenesis + 2
                    outflow tract septum morphogenesis 29
                    semaphorin-plexin signaling pathway involved in outflow tract morphogenesis + 0
paths to the root