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ONTOLOGY REPORT - ANNOTATIONS

Term:outflow tract morphogenesis
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Accession:GO:0003151 term browser browse the term
Definition:The process in which the anatomical structures of the outflow tract are generated and organized. The outflow tract is the portion of the heart through which blood flows into the arteries.


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outflow tract morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atf2 activating transcription factor 2 acts_upstream_of_or_within ISO MGI:1857283 (MGI:3759355|PMID:17767158) RGD PMID:17767158 MGI:3759355 NCBI chr 3:58,718,323...58,795,280
Ensembl chr 3:58,718,332...58,795,236 		JBrowse link
G Bmp4 bone morphogenetic protein 4 involved_in ISO RNAcentral:URS00002075FA_10090|RNAcentral:URS0000574A2C_10090|RNAcentral:URS000075EEC2_10090 (MGI:4939577|PMID:21145505) RGD PMID:21145505 MGI:4939577 NCBI chr15:19,618,538...19,633,494
Ensembl chr15:19,618,542...19,623,306 		JBrowse link
G Bmpr1a bone morphogenetic protein receptor type 1A involved_in ISO (MGI:3040576|PMID:15073157) RGD PMID:15073157 MGI:3040576 NCBI chr16:9,736,390...9,829,825
Ensembl chr16:9,736,630...9,780,616 		JBrowse link
G Bmpr2 bone morphogenetic protein receptor type 2 involved_in ISO (MGI:3851675|PMID:19409885) RGD PMID:19409885 MGI:3851675 NCBI chr 9:61,192,718...61,307,280
Ensembl chr 9:61,190,566...61,301,809 		JBrowse link
G Cited2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 involved_in
acts_upstream_of_or_within		 ISO (MGI:3054669|PMID:15475956)
MGI:2179740 (MGI:2179743|PMID:11694877)		 RGD PMID:11694877 PMID:15475956 MGI:2179743 MGI:3054669 NCBI chr 1:12,312,426...12,314,869
Ensembl chr 1:12,312,160...12,314,897 		JBrowse link
G Crkl CRK like proto-oncogene, adaptor protein acts_upstream_of_or_within ISO MGI:5763397|MGI:5763398 (MGI:5755897|PMID:25658046) RGD PMID:25658046 MGI:5755897 NCBI chr11:83,528,788...83,563,214
Ensembl chr11:83,526,530...83,563,238 		JBrowse link
G Dhrs3 dehydrogenase/reductase 3 acts_upstream_of_or_within ISO MGI:5007106 (MGI:5528782|PMID:24005908) RGD PMID:24005908 MGI:5528782 NCBI chr 5:156,747,939...156,782,420
Ensembl chr 5:156,747,962...156,782,417 		JBrowse link
G Dvl2 dishevelled segment polarity protein 2 involved_in ISO (MGI:2446944|PMID:12464179) RGD PMID:12464179 MGI:2446944 NCBI chr10:54,723,356...54,732,823
Ensembl chr10:54,723,411...54,732,820 		JBrowse link
G Eln elastin involved_in ISO
IEA		 (PMID:8132745)
GO_REF:0000107		 RGD
Ensembl		 PMID:8132745 GO_REF:0000107 NCBI chr12:21,968,544...22,011,929
Ensembl chr12:21,968,544...22,011,928 		JBrowse link
G Eya1 EYA transcriptional coactivator and phosphatase 1 acts_upstream_of_or_within ISO MGI:102780|MGI:98493|MGI:99604 (MGI:5002778|PMID:21364285) RGD PMID:21364285 MGI:5002778 NCBI chr 5:4,863,501...5,101,483
Ensembl chr 5:4,955,543...5,101,483 		JBrowse link
G Fgf8 fibroblast growth factor 8 acts_upstream_of_or_within ISO MGI:102780|MGI:109344|MGI:98493 (MGI:5002778|PMID:21364285) RGD PMID:21364285 MGI:5002778 NCBI chr 1:244,584,477...244,590,359
Ensembl chr 1:244,584,652...244,590,359 		JBrowse link
G Foxh1 forkhead box H1 involved_in ISO (MGI:3055632|PMID:15363409) RGD PMID:15363409 MGI:3055632 NCBI chr 7:108,387,969...108,391,566
Ensembl chr 7:108,387,969...108,390,049 		JBrowse link
G Fzd1 frizzled class receptor 1 acts_upstream_of_or_within ISO MGI:1888513 (MGI:4837757|PMID:20940229) RGD PMID:20940229 MGI:4837757 NCBI chr 4:29,310,303...29,314,701
Ensembl chr 4:29,310,091...29,312,643
Ensembl chr 4:29,310,091...29,312,643 		JBrowse link
G Fzd2 frizzled class receptor 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:1196625 (MGI:4837757|PMID:20940229)		 Ensembl
RGD		 PMID:20940229 GO_REF:0000107 MGI:4837757 NCBI chr10:87,561,866...87,563,776
Ensembl chr10:87,561,326...87,565,334 		JBrowse link
G Gja5 gap junction protein, alpha 5 involved_in ISO (PMID:22199024) RGD PMID:22199024 NCBI chr 2:184,602,407...184,621,952
Ensembl chr 2:184,564,475...184,621,952 		JBrowse link
G Hes1 hes family bHLH transcription factor 1 involved_in
acts_upstream_of_or_within		 ISO (MGI:4453944|PMID:20122914)
(MGI:4354447|PMID:19609448)		 RGD PMID:19609448 PMID:20122914 MGI:4354447 MGI:4453944 NCBI chr11:70,705,763...70,708,176
Ensembl chr11:70,705,764...70,708,192 		JBrowse link
G Hey1 hes-related family bHLH transcription factor with YRPW motif 1 involved_in ISO UniProtKB:Q9DBX7 (MGI:3783952|PMID:17303760) RGD PMID:17303760 MGI:3783952 NCBI chr 2:93,096,706...93,100,316
Ensembl chr 2:93,095,498...93,100,312 		JBrowse link
G Hey2 hes-related family bHLH transcription factor with YRPW motif 2 involved_in ISO (MGI:2386835|PMID:12372254) RGD PMID:12372254 MGI:2386835 NCBI chr 1:26,822,131...26,832,218
Ensembl chr 1:26,822,131...26,832,218 		JBrowse link
G Heyl hes-related family bHLH transcription factor with YRPW motif-like involved_in ISO UniProtKB:Q9WV93 (MGI:3783952|PMID:17303760) RGD PMID:17303760 MGI:3783952 NCBI chr 5:135,508,160...135,525,152
Ensembl chr 5:135,508,160...135,525,152 		JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:1857719 (MGI:1195604|PMID:9436976)		 Ensembl
RGD		 PMID:9436976 GO_REF:0000107 MGI:1195604 NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261 		JBrowse link
G Ilk integrin-linked kinase involved_in ISO (MGI:5619428|PMID:24131868) RGD PMID:24131868 MGI:5619428 NCBI chr 1:160,088,839...160,095,140
Ensembl chr 1:160,088,897...160,095,140 		JBrowse link
G Isl1 ISL LIM homeobox 1 involved_in ISO UniProtKB:Q02248 (MGI:3829137|PMID:17519333) RGD PMID:17519333 MGI:3829137 NCBI chr 2:48,079,412...48,090,704
Ensembl chr 2:48,080,522...48,095,584 		JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit acts_upstream_of_or_within ISO MGI:2149630 (MGI:1338596|PMID:10352021) RGD PMID:10352021 MGI:1338596 NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656 		JBrowse link
G Mef2c myocyte enhancer factor 2C acts_upstream_of_or_within ISO MGI:97350 (MGI:3820390|PMID:19035347) RGD PMID:19035347 MGI:3820390 NCBI chr 2:13,973,299...14,136,065
Ensembl chr 2:13,993,438...14,132,880 		JBrowse link
G Msx2 msh homeobox 2 acts_upstream_of_or_within ISO MGI:97168 (MGI:3720542|PMID:17601530) RGD PMID:17601530 MGI:3720542 NCBI chr17:11,097,214...11,102,879
Ensembl chr17:11,097,103...11,102,879 		JBrowse link
G Nedd4 NEDD4 E3 ubiquitin protein ligase acts_upstream_of_or_within ISO MGI:3799317|MGI:98737 (MGI:4452597|PMID:20026598) RGD PMID:20026598 MGI:4452597 NCBI chr 8:73,384,095...73,468,951
Ensembl chr 8:73,383,695...73,468,951 		JBrowse link
G Nipbl NIPBL, cohesin loading factor involved_in ISO (PMID:19242925) RGD PMID:19242925 NCBI chr 2:57,399,443...57,586,770
Ensembl chr 2:57,399,445...57,565,899 		JBrowse link
G Nkx2-5 NK2 homeobox 5 acts_upstream_of_or_within ISO MGI:99458 (MGI:3773736|PMID:16510504), (MGI:3820390|PMID:19035347) RGD PMID:16510504 PMID:19035347 MGI:3773736 MGI:3820390 NCBI chr10:16,340,428...16,347,004
Ensembl chr10:16,344,159...16,346,934 		JBrowse link
G Nog noggin involved_in IEA
ISO		 GO_REF:0000107
(MGI:3783944|PMID:17218603)		 Ensembl
RGD		 PMID:17218603 GO_REF:0000107 MGI:3783944 NCBI chr10:74,128,712...74,130,339
Ensembl chr10:74,128,712...74,130,339 		JBrowse link
G Notch1 notch receptor 1 involved_in ISO (PMID:18593716) RGD PMID:18593716 NCBI chr 3:9,277,955...9,323,531
Ensembl chr 3:9,278,086...9,323,531 		JBrowse link
G Npy1r neuropeptide Y receptor Y1 involved_in ISO (PMID:19593212) RGD PMID:19593212 NCBI chr16:23,037,788...23,047,330
Ensembl chr16:23,037,789...23,046,759 		JBrowse link
G Npy2r neuropeptide Y receptor Y2 involved_in ISO (PMID:19593212) RGD PMID:19593212 NCBI chr 2:167,901,999...167,912,165
Ensembl chr 2:167,903,879...167,905,024 		JBrowse link
G Npy5r neuropeptide Y receptor Y5 involved_in ISO (PMID:19593212) RGD PMID:19593212 NCBI chr16:23,055,427...23,063,384
Ensembl chr16:23,055,427...23,063,382 		JBrowse link
G Plxnd1 plexin D1 acts_upstream_of_or_within ISO MGI:5544786 (MGI:5509072|PMID:23918385) RGD PMID:23918385 MGI:5509072 NCBI chr 4:149,002,784...149,043,097
Ensembl chr 4:149,002,784...149,043,244 		JBrowse link
G Rbpj recombination signal binding protein for immunoglobulin kappa J region involved_in ISO (MGI:3027664|PMID:14701881) RGD PMID:14701881 MGI:3027664 NCBI chr14:57,338,493...57,523,330
Ensembl chr14:57,338,507...57,523,353 		JBrowse link
G Ryr1 ryanodine receptor 1 involved_in ISS
ISO		 GO_REF:0000024
(MGI:3764002|PMID:18003898)		 UniProt
RGD		 PMID:18003898 GO_REF:0000024 MGI:3764002 NCBI chr 1:84,292,578...84,423,799
Ensembl chr 1:84,292,578...84,423,812 		JBrowse link
G Sec24b SEC24 homolog B, COPII coat complex component acts_upstream_of_or_within ISO MGI:4440621 (MGI:4439427|PMID:20215345) RGD PMID:20215345 MGI:4439427 NCBI chr 2:218,562,670...218,632,753
Ensembl chr 2:218,562,676...218,632,699 		JBrowse link
G Sema3c semaphorin 3C acts_upstream_of_or_within ISO (PMID:19666519) RGD PMID:19666519 NCBI chr 4:17,583,212...17,747,234
Ensembl chr 4:17,583,212...17,746,534 		JBrowse link
G Sfrp2 secreted frizzled-related protein 2 involved_in ISO (PMID:19593212) RGD PMID:19593212 NCBI chr 2:169,089,517...169,097,064
Ensembl chr 2:169,089,517...169,097,063 		JBrowse link
G Six1 SIX homeobox 1 acts_upstream_of_or_within ISO MGI:109344|MGI:98493|MGI:99604 (MGI:5002778|PMID:21364285) RGD PMID:21364285 MGI:5002778 NCBI chr 6:91,746,739...91,751,975
Ensembl chr 6:91,746,739...91,751,975 		JBrowse link
G Smarca4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 acts_upstream_of_or_within ISO MGI:3605892 (MGI:5469230|PMID:23319608) RGD PMID:23319608 MGI:5469230 NCBI chr 8:20,167,717...20,258,975
Ensembl chr 8:20,167,717...20,258,975 		JBrowse link
G Sox11 SRY-box transcription factor 11 involved_in ISS
ISO		 GO_REF:0000024
(MGI:3052265|PMID:15254231)		 UniProt
RGD		 PMID:15254231 GO_REF:0000024 MGI:3052265 NCBI chr 6:44,008,333...44,010,354
Ensembl chr 6:44,008,340...44,010,354 		JBrowse link
G Sox17 SRY-box transcription factor 17 involved_in ISO UniProtKB:P43680 (MGI:3716256|PMID:17610846) RGD PMID:17610846 MGI:3716256 NCBI chr 5:15,016,660...15,022,228
Ensembl chr 5:15,016,731...15,022,228 		JBrowse link
G Tbx1 T-box transcription factor 1 involved_in
acts_upstream_of_or_within		 ISS
ISO		 GO_REF:0000024
MGI:102780|MGI:109344|MGI:2179190|MGI:3664784|MGI:99604 (MGI:3770747|PMID:17916582), (MGI:4353596|PMID:18583714), (MGI:5002778|PMID:21364285)		 UniProt
RGD		 PMID:17916582 PMID:18583714 PMID:21364285 GO_REF:0000024 MGI:3770747 MGI:4353596 MGI:5002778 NCBI chr11:82,409,275...82,419,058
Ensembl chr11:82,409,275...82,418,380 		JBrowse link
G Tbx2 T-box transcription factor 2 involved_in ISO (MGI:3039059|PMID:15042700), (MGI:3487212|PMID:15459098), (MGI:5300829|PMID:22186728) RGD PMID:15042700 PMID:15459098 PMID:22186728 MGI:3039059 MGI:3487212 MGI:5300829 NCBI chr10:70,679,670...70,688,868
Ensembl chr10:70,679,518...70,688,529 		JBrowse link
G Tbx20 T-box transcription factor 20 involved_in ISO (MGI:3604925|PMID:15843409) RGD PMID:15843409 MGI:3604925 NCBI chr 8:23,200,104...23,258,218
Ensembl chr 8:23,204,507...23,258,175 		JBrowse link
G Tbx3 T-box transcription factor 3 acts_upstream_of_or_within ISO MGI:2655214 (MGI:4412356|PMID:18723448) RGD PMID:18723448 MGI:4412356 NCBI chr12:36,879,924...36,894,849
Ensembl chr12:36,881,445...36,893,708 		JBrowse link
G Tfap2a transcription factor AP-2 alpha acts_upstream_of_or_within ISO MGI:2176682 (MGI:2156913|PMID:11744375) RGD PMID:11744375 MGI:2156913 NCBI chr17:24,028,716...24,047,507
Ensembl chr17:24,024,432...24,047,507 		JBrowse link
G Tgfb2 transforming growth factor, beta 2 involved_in ISO (MGI:5300829|PMID:22186728) RGD PMID:22186728 MGI:5300829 NCBI chr13:98,160,075...98,261,771
Ensembl chr13:98,160,087...98,261,405 		JBrowse link
G Tgfbr2 transforming growth factor, beta receptor 2 involved_in ISO (MGI:3801267|PMID:17050629) RGD PMID:17050629 MGI:3801267 NCBI chr 8:115,794,537...115,883,615
Ensembl chr 8:115,794,537...115,883,228 		JBrowse link
G Tgfbr3 transforming growth factor beta receptor 3 involved_in ISO (MGI:3818140|PMID:17704211) RGD PMID:17704211 MGI:3818140 NCBI chr14:2,489,397...2,665,383
Ensembl chr14:2,489,397...2,663,341 		JBrowse link
G Thbs1 thrombospondin 1 acts_upstream_of_or_within ISO MGI:97297 (MGI:4452597|PMID:20026598) RGD PMID:20026598 MGI:4452597 NCBI chr 3:105,056,286...105,071,445
Ensembl chr 3:105,056,292...105,071,440 		JBrowse link
G Vegfa vascular endothelial growth factor A involved_in ISO (MGI:4461879|PMID:18093989) RGD PMID:18093989 MGI:4461879 NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641 		JBrowse link
G Wnt11 Wnt family member 11 acts_upstream_of_or_within ISO MGI:2665014 (MGI:3759355|PMID:17767158) RGD PMID:17767158 MGI:3759355 NCBI chr 1:153,134,503...153,154,294
Ensembl chr 1:153,138,197...153,154,294 		JBrowse link
G Zfpm1 zinc finger protein, multitype 1 involved_in ISO (MGI:3583527|PMID:14614148) RGD PMID:14614148 MGI:3583527 NCBI chr19:50,334,352...50,391,029
Ensembl chr19:50,334,682...50,390,591 		JBrowse link
apoptotic process involved in outflow tract morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Foxc1 forkhead box C1 acts_upstream_of ISO MGI:1347481 (MGI:3701735|PMID:16839542) RGD PMID:16839542 MGI:3701735 NCBI chr17:32,631,379...32,635,361
Ensembl chr17:32,633,142...32,634,803 		JBrowse link
G Foxc2 forkhead box C2 acts_upstream_of
involved_in		 ISO
IEA		 MGI:1347466 (MGI:3701735|PMID:16839542)
GO_REF:0000107		 RGD
Ensembl		 PMID:16839542 GO_REF:0000107 MGI:3701735 NCBI chr19:49,186,034...49,188,736
Ensembl chr19:49,185,662...49,188,737 		JBrowse link
canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ctnnb1 catenin beta 1 involved_in ISO (MGI:2446944|PMID:12464179) RGD PMID:12464179 MGI:2446944 NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111 		JBrowse link
G Lrp6 LDL receptor related protein 6 acts_upstream_of_or_within ISO MGI:2156191 (MGI:4413394|PMID:19705442) RGD PMID:19705442 MGI:4413394 NCBI chr 4:167,266,581...167,400,155
Ensembl chr 4:167,270,353...167,400,497 		JBrowse link
cardiac neural crest cell development involved in outflow tract morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dicer1 dicer 1 ribonuclease III acts_upstream_of_or_within ISO MGI:3589208 (MGI:4849577|PMID:21098571) RGD PMID:21098571 MGI:4849577 NCBI chr 6:123,627,529...123,692,278
Ensembl chr 6:123,631,250...123,693,965 		JBrowse link
G Hand2 heart and neural crest derivatives expressed 2 involved_in ISO (MGI:4413411|PMID:19008477) RGD PMID:19008477 MGI:4413411 NCBI chr16:32,917,826...32,919,880
Ensembl chr16:32,917,823...32,919,891 		JBrowse link
G Hes1 hes family bHLH transcription factor 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(MGI:4354447|PMID:19609448)		 Ensembl
RGD		 PMID:19609448 GO_REF:0000107 MGI:4354447 NCBI chr11:70,705,763...70,708,176
Ensembl chr11:70,705,764...70,708,192 		JBrowse link
G Jag1 jagged canonical Notch ligand 1 involved_in IEA
ISO		 GO_REF:0000107
(MGI:4359139|PMID:19509466)		 Ensembl
RGD		 PMID:19509466 GO_REF:0000107 MGI:4359139 NCBI chr 3:124,406,794...124,442,220
Ensembl chr 3:124,406,794...124,442,209 		JBrowse link
G Twist1 twist family bHLH transcription factor 1 acts_upstream_of_or_within ISO MGI:1857265 (MGI:3805126|PMID:18539270) RGD PMID:18539270 MGI:3805126 NCBI chr 6:50,674,910...50,676,904
Ensembl chr 6:50,674,678...50,677,653 		JBrowse link
cardiac neural crest cell migration involved in outflow tract morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdc42 cell division cycle 42 involved_in ISO (MGI:6362316|PMID:31219639) RGD PMID:31219639 MGI:6362316 NCBI chr 5:149,555,069...149,593,239
Ensembl chr 5:149,553,724...149,593,111 		JBrowse link
G Edn1 endothelin 1 involved_in ISO (MGI:6362316|PMID:31219639) RGD PMID:31219639 MGI:6362316 NCBI chr17:22,454,924...22,460,812
Ensembl chr17:22,454,420...22,460,885 		JBrowse link
G Ednra endothelin receptor type A involved_in ISO MGI:1857473|MGI:2687362 (MGI:6362316|PMID:31219639) RGD PMID:31219639 MGI:6362316 NCBI chr19:30,233,540...30,303,727
Ensembl chr19:30,233,571...30,297,049 		JBrowse link
G Folr1 folate receptor alpha involved_in ISO (MGI:3721767|PMID:17286298) RGD PMID:17286298 MGI:3721767 NCBI chr 1:156,219,460...156,238,436
Ensembl chr 1:156,219,460...156,230,667 		JBrowse link
G Hand2 heart and neural crest derivatives expressed 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:2386570|MGI:3803647 (MGI:4453274|PMID:20144608)		 Ensembl
RGD		 PMID:20144608 GO_REF:0000107 MGI:4453274 NCBI chr16:32,917,826...32,919,880
Ensembl chr16:32,917,823...32,919,891 		JBrowse link
G Nrp1 neuropilin 1 NOT|involved_in ISO (MGI:5693177|PMID:26053665) RGD PMID:26053665 MGI:5693177 NCBI chr19:56,359,455...56,514,628
Ensembl chr19:56,359,455...56,513,633 		JBrowse link
G Pitx2 paired-like homeodomain 2 involved_in ISO (MGI:2446944|PMID:12464179) RGD PMID:12464179 MGI:2446944 NCBI chr 2:217,717,738...217,737,293
Ensembl chr 2:217,717,693...217,737,293 		JBrowse link
G Twist1 twist family bHLH transcription factor 1 acts_upstream_of_or_within ISO MGI:1857265 (MGI:3805126|PMID:18539270) RGD PMID:18539270 MGI:3805126 NCBI chr 6:50,674,910...50,676,904
Ensembl chr 6:50,674,678...50,677,653 		JBrowse link
cell proliferation involved in outflow tract morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hand2 heart and neural crest derivatives expressed 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:2386570|MGI:3803647 (MGI:4453274|PMID:20144608)		 Ensembl
RGD		 PMID:20144608 GO_REF:0000107 MGI:4453274 NCBI chr16:32,917,826...32,919,880
Ensembl chr16:32,917,823...32,919,891 		JBrowse link
G Pitx2 paired-like homeodomain 2 involved_in
acts_upstream_of_or_within		 ISO (MGI:2446944|PMID:12464179)
MGI:1857844|MGI:2445429 (MGI:3701739|PMID:16836994)		 RGD PMID:12464179 PMID:16836994 MGI:2446944 MGI:3701739 NCBI chr 2:217,717,738...217,737,293
Ensembl chr 2:217,717,693...217,737,293 		JBrowse link
negative regulation of apoptotic process involved in outflow tract morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Foxc1 forkhead box C1 acts_upstream_of_or_within ISO MGI:1347481 (MGI:3701735|PMID:16839542) RGD PMID:16839542 MGI:3701735 NCBI chr17:32,631,379...32,635,361
Ensembl chr17:32,633,142...32,634,803 		JBrowse link
G Foxc2 forkhead box C2 acts_upstream_of_or_within ISO MGI:1347466 (MGI:3701735|PMID:16839542) RGD PMID:16839542 MGI:3701735 NCBI chr19:49,186,034...49,188,736
Ensembl chr19:49,185,662...49,188,737 		JBrowse link
negative regulation of planar cell polarity pathway involved in outflow tract morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lrp6 LDL receptor related protein 6 acts_upstream_of_or_within ISO MGI:98958 (MGI:4830282|PMID:19056682) RGD PMID:19056682 MGI:4830282 NCBI chr 4:167,266,581...167,400,155
Ensembl chr 4:167,270,353...167,400,497 		JBrowse link
outflow tract septum morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acvr1 activin A receptor type 1 NOT|involved_in ISO (MGI:3610266|PMID:16140292) RGD PMID:16140292 MGI:3610266 NCBI chr 3:42,978,558...43,097,892
Ensembl chr 3:42,978,561...43,098,241 		JBrowse link
G Bmp4 bone morphogenetic protein 4 involved_in IEA
ISO		 GO_REF:0000107
(MGI:3039210|PMID:15070745), (MGI:3814273|PMID:18924235)		 Ensembl
RGD		 PMID:15070745 PMID:18924235 GO_REF:0000107 MGI:3039210 MGI:3814273 NCBI chr15:19,618,538...19,633,494
Ensembl chr15:19,618,542...19,623,306 		JBrowse link
G Bmpr1a bone morphogenetic protein receptor type 1A involved_in ISO (MGI:3040576|PMID:15073157) RGD PMID:15073157 MGI:3040576 NCBI chr16:9,736,390...9,829,825
Ensembl chr16:9,736,630...9,780,616 		JBrowse link
G Bmpr2 bone morphogenetic protein receptor type 2 NOT|involved_in ISO (MGI:3851675|PMID:19409885)
(MGI:2429424|PMID:12441304)		 RGD PMID:12441304 PMID:19409885 MGI:2429424 MGI:3851675 NCBI chr 9:61,192,718...61,307,280
Ensembl chr 9:61,190,566...61,301,809 		JBrowse link
G Dvl3 dishevelled segment polarity protein 3 acts_upstream_of_or_within ISO MGI:3831892 (MGI:3821448|PMID:19008950) RGD PMID:19008950 MGI:3821448 NCBI chr11:80,365,446...80,382,641
Ensembl chr11:80,366,117...80,382,462 		JBrowse link
G Eng endoglin involved_in ISO UniProtKB:P97471 (MGI:3721185|PMID:17628518) RGD PMID:17628518 MGI:3721185 NCBI chr 3:15,934,566...15,972,618
Ensembl chr 3:15,934,518...15,973,230 		JBrowse link
G Fgf8 fibroblast growth factor 8 involved_in ISO UniProtKB:P70323 (MGI:5285152|PMID:20807544) RGD PMID:20807544 MGI:5285152 NCBI chr 1:244,584,477...244,590,359
Ensembl chr 1:244,584,652...244,590,359 		JBrowse link
G Fgfr2 fibroblast growth factor receptor 2 acts_upstream_of_or_within ISO MGI:2153818 (MGI:3653131|PMID:16687131) RGD PMID:16687131 MGI:3653131 NCBI chr 1:184,745,418...184,850,655
Ensembl chr 1:184,745,420...184,850,626 		JBrowse link
G Gata6 GATA binding protein 6 involved_in ISO
IEA		 (PMID:19666519)
GO_REF:0000107		 RGD
Ensembl		 PMID:19666519 GO_REF:0000107 NCBI chr18:2,188,121...2,219,532
Ensembl chr18:2,188,121...2,219,532 		JBrowse link
G Isl1 ISL LIM homeobox 1 involved_in ISO UniProtKB:Q02248 (MGI:3829137|PMID:17519333) RGD PMID:17519333 MGI:3829137 NCBI chr 2:48,079,412...48,090,704
Ensembl chr 2:48,080,522...48,095,584 		JBrowse link
G Lrp2 LDL receptor related protein 2 involved_in ISS
ISO		 GO_REF:0000024
(MGI:5770180|PMID:26822476)		 UniProt
RGD		 PMID:26822476 GO_REF:0000024 MGI:5770180 NCBI chr 3:54,189,305...54,346,769
Ensembl chr 3:54,189,308...54,346,708 		JBrowse link
G Msx2 msh homeobox 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:97168 (MGI:3720542|PMID:17601530)		 Ensembl
RGD		 PMID:17601530 GO_REF:0000107 MGI:3720542 NCBI chr17:11,097,214...11,102,879
Ensembl chr17:11,097,103...11,102,879 		JBrowse link
G Nkx2-5 NK2 homeobox 5 involved_in IEA
ISO		 GO_REF:0000107
(PMID:20807224)		 Ensembl
RGD		 PMID:20807224 GO_REF:0000107 NCBI chr10:16,340,428...16,347,004
Ensembl chr10:16,344,159...16,346,934 		JBrowse link
G Nrp1 neuropilin 1 involved_in ISO (MGI:5693177|PMID:26053665) RGD PMID:26053665 MGI:5693177 NCBI chr19:56,359,455...56,514,628
Ensembl chr19:56,359,455...56,513,633 		JBrowse link
G Nrp2 neuropilin 2 involved_in ISO UniProtKB:Q62181 (MGI:5693177|PMID:26053665) RGD PMID:26053665 MGI:5693177 NCBI chr 9:64,122,815...64,238,007
Ensembl chr 9:64,123,132...64,237,958 		JBrowse link
G Parva parvin, alpha involved_in ISS
ISO
IEA		 GO_REF:0000024
(MGI:4368016|PMID:19798050)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:19798050 GO_REF:0000024 GO_REF:0000107 MGI:4368016 NCBI chr 1:166,547,202...166,704,958
Ensembl chr 1:166,547,132...166,704,950 		JBrowse link
G Rara retinoic acid receptor, alpha acts_upstream_of_or_within ISO MGI:97857 (MGI:1270092|PMID:9659935) RGD PMID:9659935 MGI:1270092 NCBI chr10:83,883,490...83,928,932
Ensembl chr10:83,893,384...83,928,142 		JBrowse link
G Rarb retinoic acid receptor, beta acts_upstream_of_or_within ISO MGI:97856 (MGI:1270092|PMID:9659935) RGD PMID:9659935 MGI:1270092 NCBI chr15:8,700,533...9,051,288
Ensembl chr15:8,406,492...9,051,288 		JBrowse link
G Robo1 roundabout guidance receptor 1 involved_in ISO UniProtKB:Q7TPD3 (MGI:5913048|PMID:25691540) RGD PMID:25691540 MGI:5913048 NCBI chr11:10,580,863...11,621,672
Ensembl chr11:10,580,908...11,620,203 		JBrowse link
G Robo2 roundabout guidance receptor 2 involved_in ISO UniProtKB:O89026 (MGI:5913048|PMID:25691540) RGD PMID:25691540 MGI:5913048 NCBI chr11:12,528,949...14,096,726
Ensembl chr11:12,528,951...13,041,536 		JBrowse link
G Sema3c semaphorin 3C involved_in ISO UniProtKB:O35375|UniProtKB:P97333 (MGI:5693177|PMID:26053665) RGD PMID:26053665 MGI:5693177 NCBI chr 4:17,583,212...17,747,234
Ensembl chr 4:17,583,212...17,746,534 		JBrowse link
G Smad4 SMAD family member 4 involved_in IEA
ISO		 GO_REF:0000107
UniProtKB:Q63961 (MGI:3721185|PMID:17628518)		 Ensembl
RGD		 PMID:17628518 GO_REF:0000107 MGI:3721185 NCBI chr18:67,243,742...67,274,438
Ensembl chr18:67,243,742...67,274,438 		JBrowse link
G Smad6 SMAD family member 6 involved_in ISO (MGI:1352979|PMID:10655064) RGD PMID:10655064 MGI:1352979 NCBI chr 8:64,450,114...64,519,673
Ensembl chr 8:64,450,114...64,519,763 		JBrowse link
G Tbx1 T-box transcription factor 1 involved_in ISS
ISO		 GO_REF:0000024
(MGI:5285152|PMID:20807544)		 UniProt
RGD		 PMID:20807544 GO_REF:0000024 MGI:5285152 NCBI chr11:82,409,275...82,419,058
Ensembl chr11:82,409,275...82,418,380 		JBrowse link
G Tbx2 T-box transcription factor 2 involved_in ISO (MGI:3487212|PMID:15459098) RGD PMID:15459098 MGI:3487212 NCBI chr10:70,679,670...70,688,868
Ensembl chr10:70,679,518...70,688,529 		JBrowse link
G Tbx20 T-box transcription factor 20 involved_in ISO (PMID:18275040), (PMID:18834961)
(MGI:3604925|PMID:15843409)		 RGD PMID:15843409 PMID:18275040 PMID:18834961 MGI:3604925 NCBI chr 8:23,200,104...23,258,218
Ensembl chr 8:23,204,507...23,258,175 		JBrowse link
G Tgfb2 transforming growth factor, beta 2 involved_in ISO (MGI:3609313|PMID:11390347), (MGI:894212|PMID:9217007) RGD PMID:9217007 PMID:11390347 MGI:3609313 MGI:894212 NCBI chr13:98,160,075...98,261,771
Ensembl chr13:98,160,087...98,261,405 		JBrowse link
G Tgfbr2 transforming growth factor, beta receptor 2 involved_in ISO (MGI:4821522|PMID:20652948) RGD PMID:20652948 MGI:4821522 NCBI chr 8:115,794,537...115,883,615
Ensembl chr 8:115,794,537...115,883,228 		JBrowse link
G Zfpm2 zinc finger protein, multitype 2 involved_in ISO (PMID:20807224) RGD PMID:20807224 NCBI chr 7:71,678,658...72,116,209
Ensembl chr 7:71,678,880...72,116,205 		JBrowse link
planar cell polarity pathway involved in outflow tract morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lrp6 LDL receptor related protein 6 acts_upstream_of ISO MGI:98958 (MGI:4830282|PMID:19056682) RGD PMID:19056682 MGI:4830282 NCBI chr 4:167,266,581...167,400,155
Ensembl chr 4:167,270,353...167,400,497 		JBrowse link
G Wnt5a Wnt family member 5A acts_upstream_of_or_within ISO MGI:1857617 (MGI:4830282|PMID:19056682) RGD PMID:19056682 MGI:4830282 NCBI chr16:3,695,667...3,718,234
Ensembl chr16:3,697,032...3,718,234 		JBrowse link
positive regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp4 bone morphogenetic protein 4 involved_in IEA
ISO		 GO_REF:0000107
UniProtKB:P23359 (MGI:5502250|PMID:23863481)		 Ensembl
RGD		 PMID:23863481 GO_REF:0000107 MGI:5502250 NCBI chr15:19,618,538...19,633,494
Ensembl chr15:19,618,542...19,623,306 		JBrowse link
G Bmp7 bone morphogenetic protein 7 involved_in ISO UniProtKB:P21275 (MGI:5502250|PMID:23863481) RGD PMID:23863481 MGI:5502250 NCBI chr 3:161,639,915...161,716,938
Ensembl chr 3:161,516,462...161,716,788 		JBrowse link
G Sema3c semaphorin 3C involved_in ISO (MGI:5693177|PMID:26053665) RGD PMID:26053665 MGI:5693177 NCBI chr 4:17,583,212...17,747,234
Ensembl chr 4:17,583,212...17,746,534 		JBrowse link
positive regulation of cell proliferation involved in outflow tract morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp4 bone morphogenetic protein 4 involved_in IEA
ISO		 GO_REF:0000107
(MGI:3039210|PMID:15070745)		 Ensembl
RGD		 PMID:15070745 GO_REF:0000107 MGI:3039210 NCBI chr15:19,618,538...19,633,494
Ensembl chr15:19,618,542...19,623,306 		JBrowse link
positive regulation of semaphorin-plexin signaling pathway involved in outflow tract morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hand2 heart and neural crest derivatives expressed 2 involved_in IEA
ISO		 GO_REF:0000107
(MGI:4413411|PMID:19008477)		 Ensembl
RGD		 PMID:19008477 GO_REF:0000107 MGI:4413411 NCBI chr16:32,917,826...32,919,880
Ensembl chr16:32,917,823...32,919,891 		JBrowse link
regulation of apoptotic process involved in outflow tract morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tgfb2 transforming growth factor, beta 2 involved_in ISO (MGI:3609313|PMID:11390347) RGD PMID:11390347 MGI:3609313 NCBI chr13:98,160,075...98,261,771
Ensembl chr13:98,160,087...98,261,405 		JBrowse link
regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Eng endoglin NOT|involved_in ISO (MGI:3721185|PMID:17628518) RGD PMID:17628518 MGI:3721185 NCBI chr 3:15,934,566...15,972,618
Ensembl chr 3:15,934,518...15,973,230 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18877
    developmental process 6926
      anatomical structure morphogenesis 2992
        outflow tract morphogenesis 86
          apoptotic process involved in outflow tract morphogenesis + 3
          cardiac neural crest cell delamination involved in outflow tract morphogenesis 0
          cardiac neural crest cell development involved in outflow tract morphogenesis + 15
          cell proliferation involved in outflow tract morphogenesis + 5
          outflow tract septum morphogenesis 29
          planar cell polarity pathway involved in outflow tract morphogenesis + 2
          semaphorin-plexin signaling pathway involved in outflow tract morphogenesis + 1
Path 2
Term Annotations click to browse term
  biological_process 18877
    developmental process 6926
      anatomical structure development 6400
        multicellular organism development 5454
          system development 4923
            circulatory system development 1325
              heart development 718
                heart morphogenesis 288
                  outflow tract morphogenesis 86
                    apoptotic process involved in outflow tract morphogenesis + 3
                    cardiac neural crest cell delamination involved in outflow tract morphogenesis 0
                    cardiac neural crest cell development involved in outflow tract morphogenesis + 15
                    cell proliferation involved in outflow tract morphogenesis + 5
                    outflow tract septum morphogenesis 29
                    planar cell polarity pathway involved in outflow tract morphogenesis + 2
                    semaphorin-plexin signaling pathway involved in outflow tract morphogenesis + 1
paths to the root