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ONTOLOGY REPORT - ANNOTATIONS

Term:outflow tract morphogenesis
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Accession:GO:0003151 term browser browse the term
Definition:The process in which the anatomical structures of the outflow tract are generated and organized. The outflow tract is the portion of the heart through which blood flows into the arteries.

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outflow tract morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atf2 activating transcription factor 2 acts_upstream_of_or_within ISO MGI:1857283 (MGI:3759355|PMID:17767158) RGD PMID:17767158 MGI:3759355 NCBI chr 3:60,721,137...60,795,951
Ensembl chr 3:60,721,135...60,795,951 		JBrowse link
G Bmp4 bone morphogenetic protein 4 involved_in ISO RNAcentral:URS00002075FA_10090|RNAcentral:URS0000574A2C_10090|RNAcentral:URS000075EEC2_10090 (MGI:4939577|PMID:21145505) RGD PMID:21145505 MGI:4939577 NCBI chr15:20,776,060...20,791,013
Ensembl chr15:20,776,054...20,822,740 		JBrowse link
G Bmpr1a bone morphogenetic protein receptor type 1A involved_in ISO (MGI:3040576|PMID:15073157) RGD PMID:15073157 MGI:3040576 NCBI chr16:10,758,278...10,852,170
Ensembl chr16:10,758,527...10,802,512 		JBrowse link
G Bmpr2 bone morphogenetic protein receptor type 2 involved_in ISO (MGI:3851675|PMID:19409885) RGD PMID:19409885 MGI:3851675 NCBI chr 9:66,568,074...66,683,019
Ensembl chr 9:66,568,074...66,676,494 		JBrowse link
G Cited2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 involved_in
acts_upstream_of_or_within		 ISO (MGI:3054669|PMID:15475956)
MGI:2179740 (MGI:2179743|PMID:11694877)		 RGD PMID:11694877 PMID:15475956 MGI:2179743 MGI:3054669 NCBI chr 1:12,823,363...12,825,806
Ensembl chr 1:12,823,363...12,825,786 		JBrowse link
G Crkl CRK like proto-oncogene, adaptor protein acts_upstream_of_or_within ISO MGI:5763397|MGI:5763398 (MGI:5755897|PMID:25658046) RGD PMID:25658046 MGI:5755897 NCBI chr11:87,338,606...87,356,644
Ensembl chr11:87,778,312...87,815,043 		JBrowse link
G Dhrs3 dehydrogenase/reductase 3 acts_upstream_of_or_within ISO MGI:5007106 (MGI:5528782|PMID:24005908) RGD PMID:24005908 MGI:5528782 NCBI chr 5:162,809,090...162,843,385
Ensembl chr 5:162,808,646...162,843,383 		JBrowse link
G Dvl2 dishevelled segment polarity protein 2 involved_in ISO (MGI:2446944|PMID:12464179) RGD PMID:12464179 MGI:2446944 NCBI chr10:56,609,810...56,619,269
Ensembl chr10:56,610,051...56,619,269 		JBrowse link
G Eln elastin involved_in ISO
IEA		 (PMID:8132745)
GO_REF:0000107		 RGD
Ensembl		 PMID:8132745 GO_REF:0000107 NCBI chr12:24,978,478...25,021,864
Ensembl chr12:24,978,483...25,021,863 		JBrowse link
G Eya1 EYA transcriptional coactivator and phosphatase 1 acts_upstream_of_or_within ISO MGI:102780|MGI:98493|MGI:99604 (MGI:5002778|PMID:21364285) RGD PMID:21364285 MGI:5002778 NCBI chr 5:4,275,728...4,495,525
Ensembl chr 5:4,373,626...4,513,142 		JBrowse link
G Fgf8 fibroblast growth factor 8 acts_upstream_of_or_within ISO MGI:102780|MGI:109344|MGI:98493 (MGI:5002778|PMID:21364285) RGD PMID:21364285 MGI:5002778 NCBI chr 1:265,492,949...265,498,965
Ensembl chr 1:265,493,124...265,498,831 		JBrowse link
G Foxh1 forkhead box H1 involved_in ISO (MGI:3055632|PMID:15363409) RGD PMID:15363409 MGI:3055632 NCBI chr 7:117,730,307...117,733,076
Ensembl chr 7:117,730,307...117,732,387 		JBrowse link
G Fzd1 frizzled class receptor 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:1888513 (MGI:4837757|PMID:20940229)		 Ensembl
RGD		 PMID:20940229 GO_REF:0000107 MGI:4837757 NCBI chr 4:26,470,864...26,475,262
Ensembl chr 4:26,470,864...26,475,262 		JBrowse link
G Fzd2 frizzled class receptor 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:1196625 (MGI:4837757|PMID:20940229)		 Ensembl
RGD		 PMID:20940229 GO_REF:0000107 MGI:4837757 NCBI chr10:90,550,147...90,552,057
Ensembl chr10:90,550,147...90,552,057 		JBrowse link
G Gja5 gap junction protein, alpha 5 involved_in ISO (PMID:22199024) RGD PMID:22199024 NCBI chr 2:199,162,745...199,184,942
Ensembl chr 2:199,162,745...199,184,939 		JBrowse link
G Hes1 hes family bHLH transcription factor 1 involved_in
acts_upstream_of_or_within		 ISO (MGI:4453944|PMID:20122914)
(MGI:4354447|PMID:19609448)		 RGD PMID:19609448 PMID:20122914 MGI:4354447 MGI:4453944 NCBI chr11:74,312,837...74,315,249
Ensembl chr11:74,312,806...74,315,248 		JBrowse link
G Hey1 hes-related family bHLH transcription factor with YRPW motif 1 involved_in ISO UniProtKB:Q9DBX7 (MGI:3783952|PMID:17303760) RGD PMID:17303760 MGI:3783952 NCBI chr 2:95,320,147...95,322,701
Ensembl chr 2:95,320,283...95,322,696 		JBrowse link
G Hey2 hes-related family bHLH transcription factor with YRPW motif 2 involved_in ISO (MGI:2386835|PMID:12372254) RGD PMID:12372254 MGI:2386835 NCBI chr 1:29,191,170...29,201,257
Ensembl chr 1:29,191,192...29,201,531 		JBrowse link
G Heyl hes-related family bHLH transcription factor with YRPW motif-like involved_in ISO UniProtKB:Q9WV93 (MGI:3783952|PMID:17303760) RGD PMID:17303760 MGI:3783952 NCBI chr 5:140,923,914...140,940,905
Ensembl chr 5:140,923,914...140,940,905 		JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:1857719 (MGI:1195604|PMID:9436976)		 Ensembl
RGD		 PMID:9436976 GO_REF:0000107 MGI:1195604 NCBI chr 6:96,810,868...96,856,303
Ensembl chr 6:96,810,907...96,856,052 		JBrowse link
G Ilk integrin-linked kinase involved_in ISO (MGI:5619428|PMID:24131868) RGD PMID:24131868 MGI:5619428 NCBI chr 1:170,578,941...170,585,192
Ensembl chr 1:170,578,889...170,585,189 		JBrowse link
G Isl1 ISL LIM homeobox 1 involved_in ISO UniProtKB:Q02248 (MGI:3829137|PMID:17519333) RGD PMID:17519333 MGI:3829137 NCBI chr 2:48,488,911...48,501,217
Ensembl chr 2:48,487,736...48,501,436 		JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit acts_upstream_of_or_within ISO MGI:2149630 (MGI:1338596|PMID:10352021) RGD PMID:10352021 MGI:1338596 NCBI chr 5:114,011,184...114,014,277
Ensembl chr 5:114,011,189...114,014,277 		JBrowse link
G Mef2c myocyte enhancer factor 2C acts_upstream_of_or_within ISO MGI:97350 (MGI:3820390|PMID:19035347) RGD PMID:19035347 MGI:3820390 NCBI chr 2:11,658,534...11,822,788
Ensembl chr 2:11,658,568...11,822,787 		JBrowse link
G Msx2 msh homeobox 2 acts_upstream_of_or_within ISO MGI:97168 (MGI:3720542|PMID:17601530) RGD PMID:17601530 MGI:3720542 NCBI chr17:11,683,862...11,689,527
Ensembl chr17:11,683,862...11,689,527 		JBrowse link
G Nedd4 NEDD4 E3 ubiquitin protein ligase acts_upstream_of_or_within ISO MGI:3799317|MGI:98737 (MGI:4452597|PMID:20026598) RGD PMID:20026598 MGI:4452597 NCBI chr 8:79,323,408...79,408,842
Ensembl chr 8:79,323,408...79,408,833 		JBrowse link
G Nipbl NIPBL, cohesin loading factor involved_in ISO (PMID:19242925) RGD PMID:19242925 NCBI chr 2:57,508,830...57,676,197
Ensembl chr 2:57,509,428...57,600,820 		JBrowse link
G Nkx2-5 NK2 homeobox 5 acts_upstream_of_or_within ISO MGI:99458 (MGI:3773736|PMID:16510504), (MGI:3820390|PMID:19035347) RGD PMID:16510504 PMID:19035347 MGI:3773736 MGI:3820390 NCBI chr10:16,635,989...16,638,758
Ensembl chr10:16,635,989...16,638,764 		JBrowse link
G Nog noggin involved_in IEA
ISO		 GO_REF:0000107
(MGI:3783944|PMID:17218603)		 Ensembl
RGD		 PMID:17218603 GO_REF:0000107 MGI:3783944 NCBI chr10:76,811,759...76,813,386
Ensembl chr10:76,811,759...76,813,386 		JBrowse link
G Notch1 notch receptor 1 involved_in ISO (PMID:18593716) RGD PMID:18593716 NCBI chr 3:3,905,562...3,951,015
Ensembl chr 3:3,905,453...3,951,025 		JBrowse link
G Npy1r neuropeptide Y receptor Y1 involved_in IEA
ISO		 GO_REF:0000107
(PMID:19593212)		 Ensembl
RGD		 PMID:19593212 GO_REF:0000107 NCBI chr16:24,779,480...24,789,131
Ensembl chr16:24,779,477...24,788,740 		JBrowse link
G Npy2r neuropeptide Y receptor Y2 involved_in ISO (PMID:19593212) RGD PMID:19593212 NCBI chr 2:181,528,949...181,538,145
Ensembl chr 2:181,530,832...181,531,978 		JBrowse link
G Npy5r neuropeptide Y receptor Y5 involved_in ISO (PMID:19593212) RGD PMID:19593212 NCBI chr16:24,796,685...24,805,730
Ensembl chr16:24,797,124...24,805,079 		JBrowse link
G Plxnd1 plexin D1 acts_upstream_of_or_within ISO MGI:5544786 (MGI:5509072|PMID:23918385) RGD PMID:23918385 MGI:5509072 NCBI chr 4:147,854,309...147,894,170
Ensembl chr 4:147,854,309...147,893,992 		JBrowse link
G Rbpj recombination signal binding protein for immunoglobulin kappa J region involved_in ISO (MGI:3027664|PMID:14701881) RGD PMID:14701881 MGI:3027664 NCBI chr14:59,657,738...59,865,427
Ensembl chr14:59,658,935...59,735,450 		JBrowse link
G Ryr1 ryanodine receptor 1 involved_in ISS
ISO		 GO_REF:0000024
(MGI:3764002|PMID:18003898)		 UniProt
RGD		 PMID:18003898 GO_REF:0000024 MGI:3764002 NCBI chr 1:87,959,596...88,066,252
Ensembl chr 1:87,959,712...88,066,101 		JBrowse link
G Sec24b SEC24 homolog B, COPII coat complex component acts_upstream_of_or_within ISO MGI:4440621 (MGI:4439427|PMID:20215345) RGD PMID:20215345 MGI:4439427 NCBI chr 2:230,286,886...230,356,887
Ensembl chr 2:230,287,296...230,356,919 		JBrowse link
G Sema3c semaphorin 3C acts_upstream_of_or_within ISO (PMID:19666519) RGD PMID:19666519 NCBI chr 4:14,318,276...14,490,438
Ensembl chr 4:14,318,274...14,490,446 		JBrowse link
G Sfrp2 secreted frizzled-related protein 2 involved_in ISO (PMID:19593212) RGD PMID:19593212 NCBI chr 2:182,723,732...182,731,277
Ensembl chr 2:182,723,854...182,731,764 		JBrowse link
G Six1 SIX homeobox 1 acts_upstream_of_or_within ISO MGI:109344|MGI:98493|MGI:99604 (MGI:5002778|PMID:21364285) RGD PMID:21364285 MGI:5002778 NCBI chr 6:95,929,060...95,934,296
Ensembl chr 6:95,929,060...95,934,296 		JBrowse link
G Smarca4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 acts_upstream_of_or_within ISO MGI:3605892 (MGI:5469230|PMID:23319608) RGD PMID:23319608 MGI:5469230 NCBI chr 8:22,648,323...22,739,468
Ensembl chr 8:22,648,323...22,739,468 		JBrowse link
G Sox11 SRY-box transcription factor 11 involved_in ISS
ISO		 GO_REF:0000024
(MGI:3052265|PMID:15254231)		 UniProt
RGD		 PMID:15254231 GO_REF:0000024 MGI:3052265 NCBI chr 6:46,629,967...46,631,988
Ensembl chr 6:46,629,974...46,631,983 		JBrowse link
G Sox17 SRY-box transcription factor 17 involved_in ISO UniProtKB:P43680 (MGI:3716256|PMID:17610846) RGD PMID:17610846 MGI:3716256 NCBI chr 5:14,890,318...14,895,907
Ensembl chr 5:14,890,408...14,895,907 		JBrowse link
G Tbx1 T-box transcription factor 1 involved_in
acts_upstream_of_or_within		 ISS
ISO		 GO_REF:0000024
MGI:102780|MGI:109344|MGI:2179190|MGI:3664784|MGI:99604 (MGI:3770747|PMID:17916582), (MGI:4353596|PMID:18583714), (MGI:5002778|PMID:21364285)		 UniProt
RGD		 PMID:17916582 PMID:18583714 PMID:21364285 GO_REF:0000024 MGI:3770747 MGI:4353596 MGI:5002778 NCBI chr11:86,552,022...86,561,647
Ensembl chr11:86,552,022...86,560,969 		JBrowse link
G Tbx2 T-box transcription factor 2 involved_in ISO (MGI:3039059|PMID:15042700), (MGI:3487212|PMID:15459098) RGD PMID:15042700 PMID:15459098 MGI:3039059 MGI:3487212 NCBI chr10:73,278,932...73,290,764
Ensembl chr10:73,279,119...73,289,921 		JBrowse link
G Tbx20 T-box transcription factor 20 involved_in ISO (MGI:3604925|PMID:15843409) RGD PMID:15843409 MGI:3604925 NCBI chr 8:25,849,394...25,904,570
Ensembl chr 8:25,850,962...25,904,570 		JBrowse link
G Tbx3 T-box transcription factor 3 acts_upstream_of_or_within ISO MGI:2655214 (MGI:4412356|PMID:18723448) RGD PMID:18723448 MGI:4412356 NCBI chr12:42,479,518...42,494,588
Ensembl chr12:42,480,560...42,492,526 		JBrowse link
G Tfap2a transcription factor AP-2 alpha acts_upstream_of_or_within ISO MGI:2176682 (MGI:2156913|PMID:11744375) RGD PMID:11744375 MGI:2156913 NCBI chr17:24,653,342...24,670,457
Ensembl chr17:24,654,902...24,670,457 		JBrowse link
G Tgfbr2 transforming growth factor, beta receptor 2 involved_in ISO (MGI:3801267|PMID:17050629) RGD PMID:17050629 MGI:3801267 NCBI chr 8:124,310,288...124,399,345
Ensembl chr 8:124,312,754...124,399,494 		JBrowse link
G Tgfbr3 transforming growth factor beta receptor 3 involved_in ISO (MGI:3818140|PMID:17704211) RGD PMID:17704211 MGI:3818140 NCBI chr14:3,506,416...3,680,508
Ensembl chr14:3,506,339...3,682,545 		JBrowse link
G Thbs1 thrombospondin 1 acts_upstream_of_or_within ISO MGI:97297 (MGI:4452597|PMID:20026598) RGD PMID:20026598 MGI:4452597 NCBI chr 3:109,862,120...109,873,466
Ensembl chr 3:109,862,117...109,873,466 		JBrowse link
G Vegfa vascular endothelial growth factor A involved_in ISO (MGI:4461879|PMID:18093989) RGD PMID:18093989 MGI:4461879 NCBI chr 9:17,340,341...17,355,681
Ensembl chr 9:17,340,341...17,355,681 		JBrowse link
G Wnt11 Wnt family member 11 acts_upstream_of_or_within ISO MGI:2665014 (MGI:3759355|PMID:17767158) RGD PMID:17767158 MGI:3759355 NCBI chr 1:163,794,136...163,813,756
Ensembl chr 1:163,797,660...163,813,756 		JBrowse link
G Zfpm1 zinc finger protein, multitype 1 involved_in ISO (MGI:3583527|PMID:14614148) RGD PMID:14614148 MGI:3583527 NCBI chr19:55,094,585...55,150,994
Ensembl chr19:55,094,585...55,150,686 		JBrowse link
canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ctnnb1 catenin beta 1 involved_in IEA
ISO		 GO_REF:0000107
(MGI:2446944|PMID:12464179)		 Ensembl
RGD		 PMID:12464179 GO_REF:0000107 MGI:2446944 NCBI chr 8:129,601,511...129,628,378
Ensembl chr 8:129,617,812...129,627,372 		JBrowse link
G Lrp6 LDL receptor related protein 6 acts_upstream_of_or_within ISO MGI:2156191 (MGI:4413394|PMID:19705442) RGD PMID:19705442 MGI:4413394 NCBI chr 4:168,194,054...168,323,962
Ensembl chr 4:168,194,927...168,323,751 		JBrowse link
cardiac neural crest cell development involved in outflow tract morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dicer1 dicer 1 ribonuclease III acts_upstream_of_or_within ISO MGI:3589208 (MGI:4849577|PMID:21098571) RGD PMID:21098571 MGI:4849577 NCBI chr 6:128,388,084...128,453,234
Ensembl chr 6:128,388,053...128,434,183 		JBrowse link
G Hand2 heart and neural crest derivatives expressed 2 involved_in ISO (MGI:4413411|PMID:19008477) RGD PMID:19008477 MGI:4413411 NCBI chr16:36,371,489...36,373,551
Ensembl chr16:36,371,489...36,373,546 		JBrowse link
G Hes1 hes family bHLH transcription factor 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(MGI:4354447|PMID:19609448)		 Ensembl
RGD		 PMID:19609448 GO_REF:0000107 MGI:4354447 NCBI chr11:74,312,837...74,315,249
Ensembl chr11:74,312,806...74,315,248 		JBrowse link
G Jag1 jagged canonical Notch ligand 1 involved_in IEA
ISO		 GO_REF:0000107
(MGI:4359139|PMID:19509466)		 Ensembl
RGD		 PMID:19509466 GO_REF:0000107 MGI:4359139 NCBI chr 3:130,079,361...130,114,781
Ensembl chr 3:130,079,361...130,114,770 		JBrowse link
G Twist1 twist family bHLH transcription factor 1 acts_upstream_of_or_within ISO MGI:1857265 (MGI:3805126|PMID:18539270) RGD PMID:18539270 MGI:3805126 NCBI chr 6:53,401,241...53,403,235
Ensembl chr 6:53,401,109...53,403,214 		JBrowse link
cardiac neural crest cell migration involved in outflow tract morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Folr1 folate receptor alpha involved_in ISO (MGI:3721767|PMID:17286298) RGD PMID:17286298 MGI:3721767 NCBI chr 1:166,934,457...166,945,864
Ensembl chr 1:166,934,460...166,943,592 		JBrowse link
G Hand2 heart and neural crest derivatives expressed 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:2386570|MGI:3803647 (MGI:4453274|PMID:20144608)		 Ensembl
RGD		 PMID:20144608 GO_REF:0000107 MGI:4453274 NCBI chr16:36,371,489...36,373,551
Ensembl chr16:36,371,489...36,373,546 		JBrowse link
G Nrp1 neuropilin 1 NOT|involved_in ISO (MGI:5693177|PMID:26053665) RGD PMID:26053665 MGI:5693177 NCBI chr19:61,332,351...61,486,166
Ensembl chr19:61,332,351...61,485,858 		JBrowse link
G Pitx2 paired-like homeodomain 2 involved_in ISO (MGI:2446944|PMID:12464179) RGD PMID:12464179 MGI:2446944 NCBI chr 2:233,602,732...233,621,059
Ensembl chr 2:233,602,732...233,621,129 		JBrowse link
G Twist1 twist family bHLH transcription factor 1 acts_upstream_of_or_within ISO MGI:1857265 (MGI:3805126|PMID:18539270) RGD PMID:18539270 MGI:3805126 NCBI chr 6:53,401,241...53,403,235
Ensembl chr 6:53,401,109...53,403,214 		JBrowse link
cell proliferation involved in outflow tract morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hand2 heart and neural crest derivatives expressed 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:2386570|MGI:3803647 (MGI:4453274|PMID:20144608)		 Ensembl
RGD		 PMID:20144608 GO_REF:0000107 MGI:4453274 NCBI chr16:36,371,489...36,373,551
Ensembl chr16:36,371,489...36,373,546 		JBrowse link
G Pitx2 paired-like homeodomain 2 involved_in
acts_upstream_of_or_within		 ISO (MGI:2446944|PMID:12464179)
MGI:1857844|MGI:2445429 (MGI:3701739|PMID:16836994)		 RGD PMID:12464179 PMID:16836994 MGI:2446944 MGI:3701739 NCBI chr 2:233,602,732...233,621,059
Ensembl chr 2:233,602,732...233,621,129 		JBrowse link
negative regulation of apoptotic process involved in outflow tract morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Foxc1 forkhead box C1 acts_upstream_of_or_within ISO MGI:1347481 (MGI:3701735|PMID:16839542) RGD PMID:16839542 MGI:3701735 NCBI chr17:33,947,501...33,951,484
Ensembl chr17:33,947,506...33,951,484 		JBrowse link
G Foxc2 forkhead box C2 acts_upstream_of_or_within ISO MGI:1347466 (MGI:3701735|PMID:16839542) RGD PMID:16839542 MGI:3701735 NCBI chr19:53,044,379...53,047,081
Ensembl chr19:53,044,379...53,047,081 		JBrowse link
negative regulation of planar cell polarity pathway involved in outflow tract morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lrp6 LDL receptor related protein 6 acts_upstream_of_or_within ISO MGI:98958 (MGI:4830282|PMID:19056682) RGD PMID:19056682 MGI:4830282 NCBI chr 4:168,194,054...168,323,962
Ensembl chr 4:168,194,927...168,323,751 		JBrowse link
outflow tract septum morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acvr1 activin A receptor type 1 NOT|involved_in ISO (MGI:3610266|PMID:16140292) RGD PMID:16140292 MGI:3610266 NCBI chr 3:44,432,476...44,539,680
Ensembl chr 3:44,432,471...44,522,930 		JBrowse link
G Bmp4 bone morphogenetic protein 4 involved_in IEA
ISO		 GO_REF:0000107
(MGI:3039210|PMID:15070745), (MGI:3814273|PMID:18924235)		 Ensembl
RGD		 PMID:15070745 PMID:18924235 GO_REF:0000107 MGI:3039210 MGI:3814273 NCBI chr15:20,776,060...20,791,013
Ensembl chr15:20,776,054...20,822,740 		JBrowse link
G Bmpr1a bone morphogenetic protein receptor type 1A involved_in ISO (MGI:3040576|PMID:15073157) RGD PMID:15073157 MGI:3040576 NCBI chr16:10,758,278...10,852,170
Ensembl chr16:10,758,527...10,802,512 		JBrowse link
G Bmpr2 bone morphogenetic protein receptor type 2 NOT|involved_in ISO (MGI:3851675|PMID:19409885)
(MGI:2429424|PMID:12441304)		 RGD PMID:12441304 PMID:19409885 MGI:2429424 MGI:3851675 NCBI chr 9:66,568,074...66,683,019
Ensembl chr 9:66,568,074...66,676,494 		JBrowse link
G Dvl3 dishevelled segment polarity protein 3 acts_upstream_of_or_within ISO MGI:3831892 (MGI:3821448|PMID:19008950) RGD PMID:19008950 MGI:3821448 NCBI chr11:84,051,177...84,068,479
Ensembl chr11:84,051,078...84,068,302 		JBrowse link
G Eng endoglin involved_in ISO UniProtKB:P97471 (MGI:3721185|PMID:17628518) RGD PMID:17628518 MGI:3721185 NCBI chr 3:11,679,530...11,717,486
Ensembl chr 3:11,679,530...11,717,485 		JBrowse link
G Fgf8 fibroblast growth factor 8 involved_in ISS
ISO		 GO_REF:0000024
UniProtKB:P70323 (MGI:5285152|PMID:20807544)		 UniProt
RGD		 PMID:20807544 GO_REF:0000024 MGI:5285152 NCBI chr 1:265,492,949...265,498,965
Ensembl chr 1:265,493,124...265,498,831 		JBrowse link
G Fgfr2 fibroblast growth factor receptor 2 acts_upstream_of_or_within ISO MGI:2153818 (MGI:3653131|PMID:16687131) RGD PMID:16687131 MGI:3653131 NCBI chr 1:200,590,951...200,696,946
Ensembl chr 1:200,590,953...200,696,928 		JBrowse link
G Gata6 GATA binding protein 6 involved_in ISO
IEA		 (PMID:19666519)
GO_REF:0000107		 RGD
Ensembl		 PMID:19666519 GO_REF:0000107 NCBI chr18:2,415,821...2,447,087
Ensembl chr18:2,416,552...2,446,338 		JBrowse link
G Isl1 ISL LIM homeobox 1 involved_in ISO UniProtKB:Q02248 (MGI:3829137|PMID:17519333) RGD PMID:17519333 MGI:3829137 NCBI chr 2:48,488,911...48,501,217
Ensembl chr 2:48,487,736...48,501,436 		JBrowse link
G Lrp2 LDL receptor related protein 2 involved_in IEA
ISO
ISS		 GO_REF:0000107
(MGI:5770180|PMID:26822476)
GO_REF:0000024		 Ensembl
RGD
UniProt		 PMID:26822476 GO_REF:0000024 GO_REF:0000107 MGI:5770180 NCBI chr 3:55,665,153...55,822,484
Ensembl chr 3:55,665,145...55,822,551 		JBrowse link
G Msx2 msh homeobox 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:97168 (MGI:3720542|PMID:17601530)		 Ensembl
RGD		 PMID:17601530 GO_REF:0000107 MGI:3720542 NCBI chr17:11,683,862...11,689,527
Ensembl chr17:11,683,862...11,689,527 		JBrowse link
G Nkx2-5 NK2 homeobox 5 involved_in IEA
ISO		 GO_REF:0000107
(PMID:20807224)		 Ensembl
RGD		 PMID:20807224 GO_REF:0000107 NCBI chr10:16,635,989...16,638,758
Ensembl chr10:16,635,989...16,638,764 		JBrowse link
G Nrp1 neuropilin 1 involved_in ISO (MGI:5693177|PMID:26053665) RGD PMID:26053665 MGI:5693177 NCBI chr19:61,332,351...61,486,166
Ensembl chr19:61,332,351...61,485,858 		JBrowse link
G Nrp2 neuropilin 2 involved_in ISO UniProtKB:Q62181 (MGI:5693177|PMID:26053665) RGD PMID:26053665 MGI:5693177 NCBI chr 9:69,496,875...69,609,802
Ensembl chr 9:69,497,121...69,612,087 		JBrowse link
G Parva parvin, alpha involved_in ISS
ISO
IEA		 GO_REF:0000024
(MGI:4368016|PMID:19798050)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:19798050 GO_REF:0000024 GO_REF:0000107 MGI:4368016 NCBI chr 1:177,249,302...177,408,160
Ensembl chr 1:177,249,226...177,408,205 		JBrowse link
G Rara retinoic acid receptor, alpha acts_upstream_of_or_within ISO MGI:97857 (MGI:1270092|PMID:9659935) RGD PMID:9659935 MGI:1270092 NCBI chr10:86,838,819...86,884,224
Ensembl chr10:86,860,685...86,884,210 		JBrowse link
G Rarb retinoic acid receptor, beta acts_upstream_of_or_within ISO MGI:97856 (MGI:1270092|PMID:9659935) RGD PMID:9659935 MGI:1270092 NCBI chr15:9,915,223...10,262,599
Ensembl chr15:10,120,206...10,262,599 		JBrowse link
G Robo1 roundabout guidance receptor 1 involved_in ISO UniProtKB:Q7TPD3 (MGI:5913048|PMID:25691540) RGD PMID:25691540 MGI:5913048 NCBI chr11:9,079,291...10,146,302
Ensembl chr11:9,642,365...10,143,317 		JBrowse link
G Robo2 roundabout guidance receptor 2 involved_in ISO UniProtKB:O89026 (MGI:5913048|PMID:25691540) RGD PMID:25691540 MGI:5913048 NCBI chr11:11,062,866...12,618,793
Ensembl chr11:11,062,790...11,585,765 		JBrowse link
G Sema3c semaphorin 3C involved_in ISO UniProtKB:O35375|UniProtKB:P97333 (MGI:5693177|PMID:26053665) RGD PMID:26053665 MGI:5693177 NCBI chr 4:14,318,276...14,490,438
Ensembl chr 4:14,318,274...14,490,446 		JBrowse link
G Smad4 SMAD family member 4 involved_in IEA
ISO		 GO_REF:0000107
UniProtKB:Q63961 (MGI:3721185|PMID:17628518)		 Ensembl
RGD		 PMID:17628518 GO_REF:0000107 MGI:3721185 NCBI chr18:69,626,682...69,657,373
Ensembl chr18:69,627,757...69,671,199 		JBrowse link
G Smad6 SMAD family member 6 involved_in ISO (MGI:1352979|PMID:10655064) RGD PMID:10655064 MGI:1352979 NCBI chr 8:68,897,746...68,967,221
Ensembl chr 8:68,898,296...68,966,108 		JBrowse link
G Tbx1 T-box transcription factor 1 involved_in ISS
ISO		 GO_REF:0000024
(MGI:5285152|PMID:20807544)		 UniProt
RGD		 PMID:20807544 GO_REF:0000024 MGI:5285152 NCBI chr11:86,552,022...86,561,647
Ensembl chr11:86,552,022...86,560,969 		JBrowse link
G Tbx2 T-box transcription factor 2 involved_in ISO (MGI:3487212|PMID:15459098) RGD PMID:15459098 MGI:3487212 NCBI chr10:73,278,932...73,290,764
Ensembl chr10:73,279,119...73,289,921 		JBrowse link
G Tbx20 T-box transcription factor 20 involved_in ISO (PMID:18275040), (PMID:18834961)
(MGI:3604925|PMID:15843409)		 RGD PMID:15843409 PMID:18275040 PMID:18834961 MGI:3604925 NCBI chr 8:25,849,394...25,904,570
Ensembl chr 8:25,850,962...25,904,570 		JBrowse link
G Tgfb2 transforming growth factor, beta 2 involved_in ISO (MGI:3609313|PMID:11390347), (MGI:894212|PMID:9217007) RGD PMID:9217007 PMID:11390347 MGI:3609313 MGI:894212 NCBI chr13:105,039,639...105,142,010
Ensembl chr13:105,039,853...105,141,030 		JBrowse link
G Tgfbr2 transforming growth factor, beta receptor 2 involved_in ISO (MGI:4821522|PMID:20652948) RGD PMID:20652948 MGI:4821522 NCBI chr 8:124,310,288...124,399,345
Ensembl chr 8:124,312,754...124,399,494 		JBrowse link
G Zfpm2 zinc finger protein, multitype 2 involved_in ISO (PMID:20807224) RGD PMID:20807224 NCBI chr 7:79,471,277...79,964,405
Ensembl chr 7:79,638,046...79,964,405 		JBrowse link
planar cell polarity pathway involved in outflow tract morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Wnt5a Wnt family member 5A involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:1857617 (MGI:4830282|PMID:19056682)		 Ensembl
RGD		 PMID:19056682 GO_REF:0000107 MGI:4830282 NCBI chr16:4,469,451...4,490,271
Ensembl chr16:4,469,468...4,489,860 		JBrowse link
positive regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp4 bone morphogenetic protein 4 involved_in IEA
ISO		 GO_REF:0000107
UniProtKB:P23359 (MGI:5502250|PMID:23863481)		 Ensembl
RGD		 PMID:23863481 GO_REF:0000107 MGI:5502250 NCBI chr15:20,776,060...20,791,013
Ensembl chr15:20,776,054...20,822,740 		JBrowse link
G Bmp7 bone morphogenetic protein 7 involved_in ISO UniProtKB:P21275 (MGI:5502250|PMID:23863481) RGD PMID:23863481 MGI:5502250 NCBI chr 3:170,879,972...170,955,820
Ensembl chr 3:170,879,973...170,955,399 		JBrowse link
G Sema3c semaphorin 3C involved_in ISO (MGI:5693177|PMID:26053665) RGD PMID:26053665 MGI:5693177 NCBI chr 4:14,318,276...14,490,438
Ensembl chr 4:14,318,274...14,490,446 		JBrowse link
positive regulation of cell proliferation involved in outflow tract morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp4 bone morphogenetic protein 4 involved_in IEA
ISO		 GO_REF:0000107
(MGI:3039210|PMID:15070745)		 Ensembl
RGD		 PMID:15070745 GO_REF:0000107 MGI:3039210 NCBI chr15:20,776,060...20,791,013
Ensembl chr15:20,776,054...20,822,740 		JBrowse link
positive regulation of semaphorin-plexin signaling pathway involved in outflow tract morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hand2 heart and neural crest derivatives expressed 2 involved_in IEA
ISO		 GO_REF:0000107
(MGI:4413411|PMID:19008477)		 Ensembl
RGD		 PMID:19008477 GO_REF:0000107 MGI:4413411 NCBI chr16:36,371,489...36,373,551
Ensembl chr16:36,371,489...36,373,546 		JBrowse link
regulation of apoptotic process involved in outflow tract morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tgfb2 transforming growth factor, beta 2 involved_in ISO (MGI:3609313|PMID:11390347) RGD PMID:11390347 MGI:3609313 NCBI chr13:105,039,639...105,142,010
Ensembl chr13:105,039,853...105,141,030 		JBrowse link
regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Eng endoglin NOT|involved_in ISO (MGI:3721185|PMID:17628518) RGD PMID:17628518 MGI:3721185 NCBI chr 3:11,679,530...11,717,486
Ensembl chr 3:11,679,530...11,717,485 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19599
    developmental process 6753
      anatomical structure morphogenesis 2879
        outflow tract morphogenesis 83
          apoptotic process involved in outflow tract morphogenesis + 3
          cardiac neural crest cell delamination involved in outflow tract morphogenesis 0
          cardiac neural crest cell development involved in outflow tract morphogenesis + 12
          cell proliferation involved in outflow tract morphogenesis + 5
          outflow tract septum morphogenesis 29
          planar cell polarity pathway involved in outflow tract morphogenesis + 2
          semaphorin-plexin signaling pathway involved in outflow tract morphogenesis + 1
Path 2
Term Annotations click to browse term
  biological_process 19599
    developmental process 6753
      anatomical structure development 6178
        multicellular organism development 5617
          system development 5288
            circulatory system development 1230
              heart development 693
                heart morphogenesis 281
                  outflow tract morphogenesis 83
                    apoptotic process involved in outflow tract morphogenesis + 3
                    cardiac neural crest cell delamination involved in outflow tract morphogenesis 0
                    cardiac neural crest cell development involved in outflow tract morphogenesis + 12
                    cell proliferation involved in outflow tract morphogenesis + 5
                    outflow tract septum morphogenesis 29
                    planar cell polarity pathway involved in outflow tract morphogenesis + 2
                    semaphorin-plexin signaling pathway involved in outflow tract morphogenesis + 1
paths to the root